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Arch Venture Management, LLC Top Holdings and 13F Report (2026)

About Arch Venture Management, LLC

Investment Activity

  • Arch Venture Management, LLC has $677.09 million in total holdings as of March 31, 2026.
  • Arch Venture Management, LLC owns shares of 10 different stocks, but just 5 companies or ETFs make up 80% of its holdings.
  • Approximately 5.04% of the portfolio was purchased this quarter.
  • About 11.10% of the portfolio was sold this quarter.
  • This quarter, Arch Venture Management, LLC has purchased 9 new stocks and bought additional shares in 1 stock.
  • Arch Venture Management, LLC sold shares of 2 stocks and completely divested from 0 stocks this quarter.

Largest Holdings

MAZE THERAPEUTICS INC
$122,983,582
RAPPORT THERAPEUTICS INC
$116,672,212
Vir Biotechnology
$115,733,300
Erasca
$114,741,392
Beam Therapeutics
$108,191,346

Largest New Holdings this Quarter

370920100 - GENERATE BIOMEDICINES INC
$24,305,325 Holding

Largest Purchases this Quarter

GENERATE BIOMEDICINES INC
1,944,426 shares (about $24.31M)
LYELL IMMUNOPHARMA INC
488,090 shares (about $9.79M)

Largest Sales this Quarter

Erasca
3,963,997 shares (about $64.14M)
10x Genomics
519,705 shares (about $11.03M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofArch Venture Management, LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
MAZE THERAPEUTICS INC
$122,983,5820.0%4,120,05318.2%COM
RAPPORT THERAPEUTICS INC
$116,672,2120.0%3,728,73817.2%COM
Vir Biotechnology, Inc. stock logo
VIR
Vir Biotechnology
$115,733,3000.0%12,916,66317.1%Medical
Erasca, Inc. stock logo
ERAS
Erasca
$114,741,392$64,137,471 â–¼-35.9%7,091,55716.9%Medical
Beam Therapeutics Inc. stock logo
BEAM
Beam Therapeutics
$108,191,3460.0%4,540,13216.0%Medical
LYELL IMMUNOPHARMA INC
$65,138,070$9,791,085 â–²17.7%3,247,1629.6%COM NEW
GENERATE BIOMEDICINES INC
$24,305,325$24,305,325 â–²New Holding1,944,4263.6%COM SHS
10x Genomics stock logo
TXG
10x Genomics
$4,624,616$11,033,338 â–¼-70.5%217,8340.7%Medical
Gossamer Bio, Inc. stock logo
GOSS
Gossamer Bio
$2,646,3680.0%8,055,9160.4%Medical
Q32 BIO INC
$2,057,4940.0%320,4820.3%COM

Showing largest 100 holdings. View all holdings.
SEC Filings and Trading Data