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Octagon Capital Advisors Lp Top Holdings and 13F Report (2025)

About Octagon Capital Advisors Lp

Investment Activity

  • Octagon Capital Advisors Lp has $516.80 million in total holdings as of March 31, 2025.
  • Octagon Capital Advisors Lp owns shares of 34 different stocks, but just 19 companies or ETFs make up 80% of its holdings.
  • Approximately 27.34% of the portfolio was purchased this quarter.
  • About 25.55% of the portfolio was sold this quarter.
  • This quarter, Octagon Capital Advisors Lp has purchased 31 new stocks and bought additional shares in 4 stocks.
  • Octagon Capital Advisors Lp sold shares of 9 stocks and completely divested from 5 stocks this quarter.

Largest Holdings

NUVATION BIO INC
$48,102,208
DIANTHUS THERAPEUTICS INC
$42,477,839
ARRIVENT BIOPHARMA INC
$38,078,066

Largest New Holdings this Quarter

89532M101 - Trevi Therapeutics
$20,895,380 Holding
89157D105 - TOURMALINE BIO INC
$13,765,050 Holding
61559X104 - MoonLake Immunotherapeutics
$11,564,720 Holding
92337C203 - Verastem
$10,371,600 Holding
82835W108 - ARS Pharmaceuticals
$7,862,500 Holding

Largest Purchases this Quarter

NUVATION BIO INC
27,018,464 shares (about $47.55M)
Trevi Therapeutics
3,322,000 shares (about $20.90M)
TOURMALINE BIO INC
905,000 shares (about $13.77M)
MoonLake Immunotherapeutics
296,000 shares (about $11.56M)
Verastem
1,720,000 shares (about $10.37M)

Largest Sales this Quarter

Verona Pharma
354,000 shares (about $22.48M)
Apellis Pharmaceuticals
912,980 shares (about $19.97M)
Viridian Therapeutics
420,000 shares (about $5.66M)
Scholar Rock
159,000 shares (about $5.11M)
Nuvation Bio
1,302,907 shares (about $2.29M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofOctagon Capital Advisors Lp

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
NUVATION BIO INC
$48,102,208$47,552,497 8,650.4%27,330,8009.3%*W EXP 02/10/202
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
$45,795,780$19,966,873 -30.4%2,094,0008.9%Medical
DIANTHUS THERAPEUTICS INC
$42,477,839$4,199,410 11.0%2,341,6678.2%COM
ARRIVENT BIOPHARMA INC
$38,078,0660.0%2,059,3877.4%COM
Centessa Pharmaceuticals plc stock logo
CNTA
Centessa Pharmaceuticals
$29,119,500$1,726,348 -5.6%2,025,0005.6%Medical
Trevi Therapeutics, Inc. stock logo
TRVI
Trevi Therapeutics
$20,895,380$20,895,380 New Holding3,322,0004.0%Medical
Gossamer Bio, Inc. stock logo
GOSS
Gossamer Bio
$20,185,0000.0%18,350,0003.9%Medical
Ocular Therapeutix, Inc. stock logo
OCUL
Ocular Therapeutix
$17,775,2500.0%2,425,0003.4%Medical
Mind Medicine (MindMed) Inc. stock logo
MNMD
Mind Medicine (MindMed)
$17,655,3000.0%3,018,0003.4%Medical
Cogent Biosciences, Inc. stock logo
COGT
Cogent Biosciences
$16,550,3700.0%2,763,0003.2%Medical
KalVista Pharmaceuticals, Inc. stock logo
KALV
KalVista Pharmaceuticals
$15,809,8000.0%1,370,0003.1%Medical
Taysha Gene Therapies, Inc. stock logo
TSHA
Taysha Gene Therapies
$14,873,000$347,500 2.4%10,700,0002.9%Medical
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
$13,904,000$2,293,116 -14.2%7,900,0002.7%Medical
Verona Pharma plc stock logo
VRNA
Verona Pharma
$13,794,091$22,475,459 -62.0%217,2642.7%Medical
TOURMALINE BIO INC
$13,765,050$13,765,050 New Holding905,0002.7%COM
Merus stock logo
MRUS
Merus
$12,963,7200.0%308,0002.5%Medical
Pharvaris stock logo
PHVS
Pharvaris
$12,086,096$128,505 -1.1%769,8152.3%Medical
MoonLake Immunotherapeutics stock logo
MLTX
MoonLake Immunotherapeutics
$11,564,720$11,564,720 New Holding296,0002.2%Medical
Syndax Pharmaceuticals, Inc. stock logo
SNDX
Syndax Pharmaceuticals
$11,105,6400.0%904,0002.1%Medical
aTyr Pharma, Inc. stock logo
LIFE
aTyr Pharma
$10,727,040$8,009,040 294.7%3,552,0002.1%Medical
Scholar Rock Holding Co. stock logo
SRRK
Scholar Rock
$10,577,350$5,111,850 -32.6%329,0002.0%Medical
Verastem, Inc. stock logo
VSTM
Verastem
$10,371,600$10,371,600 New Holding1,720,0002.0%Medical
Regulus Therapeutics Inc. stock logo
RGLS
Regulus Therapeutics
$8,114,883$370,521 -4.4%4,637,0761.6%Medical
ARS Pharmaceuticals, Inc. stock logo
SPRY
ARS Pharmaceuticals
$7,862,500$7,862,500 New Holding625,0001.5%Medical
ABIVAX SA
$7,687,500$7,687,500 New Holding1,230,0001.5%SPONSORED ADS
Erasca, Inc. stock logo
ERAS
Erasca
$7,037,4090.0%5,136,7951.4%Medical
Viridian Therapeutics, Inc. stock logo
VRDN
Viridian Therapeutics
$6,066,000$5,661,600 -48.3%450,0001.2%Medical
Corbus Pharmaceuticals Holdings, Inc. stock logo
CRBP
Corbus Pharmaceuticals
$5,920,6500.0%1,115,0001.1%Medical
Unicycive Therapeutics, Inc. stock logo
UNCY
Unicycive Therapeutics
$5,749,0000.0%10,000,0001.1%Medical
MAZE THERAPEUTICS INC
$5,152,680$5,152,680 New Holding468,0001.0%COM
PERSPECTIVE THERAPEUTICS INC
$4,792,500$116,622 -2.4%2,250,0000.9%COM NEW
KALARIS THERAPEUTICS INC
$3,862,430$3,862,430 New Holding481,0000.7%COM
NEUROGENE INC
$3,548,1300.0%303,0000.7%COM
HELIX ACQUISITION CORP II
$2,825,0000.0%250,0000.5%CL A ORD SHS
Insmed Incorporated stock logo
INSM
Insmed
$0$40,181,280 -100.0%00.0%Medical
DYNE THERAPEUTICS INC
$0$15,738,080 -100.0%00.0%COM
BridgeBio Pharma, Inc. stock logo
BBIO
BridgeBio Pharma
$0$12,117,504 -100.0%00.0%Medical
ALLOVIR INC
$0$4,710,300 -100.0%00.0%COM
Mersana Therapeutics, Inc. stock logo
MRSN
Mersana Therapeutics
$0$1,418,560 -100.0%00.0%Medical

Showing largest 100 holdings. View all holdings.
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