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Octagon Capital Advisors Lp Top Holdings and 13F Report (2025)

About Octagon Capital Advisors Lp

Investment Activity

  • Octagon Capital Advisors Lp has $455.63 million in total holdings as of June 30, 2025.
  • Octagon Capital Advisors Lp owns shares of 30 different stocks, but just 16 companies or ETFs make up 80% of its holdings.
  • Approximately 13.58% of the portfolio was purchased this quarter.
  • About 37.62% of the portfolio was sold this quarter.
  • This quarter, Octagon Capital Advisors Lp has purchased 34 new stocks and bought additional shares in 7 stocks.
  • Octagon Capital Advisors Lp sold shares of 12 stocks and completely divested from 7 stocks this quarter.

Largest Holdings

DIANTHUS THERAPEUTICS INC
$43,625,256
ARRIVENT BIOPHARMA INC
$42,365,596

Largest New Holdings this Quarter

501575104 - Kymera Therapeutics
$11,608,240 Holding
23306J309 - DBV TECHNOLOGIES S A
$9,314,892 Holding
90466Y202 - UNICYCIVE THERAPEUTICS INC
$4,770,000 Holding

Largest Purchases this Quarter

ARS Pharmaceuticals
725,000 shares (about $12.65M)
Kymera Therapeutics
266,000 shares (about $11.61M)
Verona Pharma PLC American Depositary Share
119,736 shares (about $11.32M)
DBV TECHNOLOGIES S A
1,018,021 shares (about $9.31M)
UNICYCIVE THERAPEUTICS INC
1,000,000 shares (about $4.77M)

Largest Sales this Quarter

NUVATION BIO INC
27,176,688 shares (about $52.99M)
Apellis Pharmaceuticals
1,190,500 shares (about $20.61M)
Centessa Pharmaceuticals
995,000 shares (about $13.07M)
MoonLake Immunotherapeutics
148,000 shares (about $6.99M)
Mind Medicine (MindMed)
888,000 shares (about $5.76M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofOctagon Capital Advisors Lp

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
DIANTHUS THERAPEUTICS INC
$43,625,2560.0%2,341,6679.6%COM
ARRIVENT BIOPHARMA INC
$42,365,596$2,467,259 -5.5%1,946,0549.3%COM
Verona Pharma PLC American Depositary Share stock logo
VRNA
Verona Pharma PLC American Depositary Share
$31,873,460$11,324,631 55.1%337,0007.0%Medical
Taysha Gene Therapies, Inc. stock logo
TSHA
Taysha Gene Therapies
$29,088,675$4,371,675 17.7%12,592,5006.4%Medical
ARS Pharmaceuticals, Inc. stock logo
SPRY
ARS Pharmaceuticals
$23,557,500$12,651,250 116.0%1,350,0005.2%Medical
Gossamer Bio, Inc. stock logo
GOSS
Gossamer Bio
$22,570,5000.0%18,350,0005.0%Medical
Ocular Therapeutix, Inc. stock logo
OCUL
Ocular Therapeutix
$22,504,0000.0%2,425,0004.9%Medical
Merus N.V. stock logo
MRUS
Merus
$20,461,400$4,260,600 26.3%389,0004.5%Medical
Trevi Therapeutics, Inc. stock logo
TRVI
Trevi Therapeutics
$20,085,840$1,914,500 10.5%3,672,0004.4%Medical
Cogent Biosciences, Inc. stock logo
COGT
Cogent Biosciences
$19,838,3400.0%2,763,0004.4%Medical
aTyr Pharma, Inc. stock logo
LIFE
aTyr Pharma
$19,367,400$1,358,760 7.5%3,820,0004.3%Medical
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
$15,639,585$20,607,555 -56.9%903,5003.4%Medical
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
$14,998,101$406,899 -2.6%7,691,3343.3%Medical
TOURMALINE BIO INC
$14,470,9500.0%905,0003.2%COM
KalVista Pharmaceuticals, Inc. stock logo
KALV
KalVista Pharmaceuticals
$14,395,030$1,092,820 -7.1%1,273,3333.2%Medical
Mind Medicine (MindMed) Inc. stock logo
MNMD
Mind Medicine (MindMed)
$13,823,700$5,763,120 -29.4%2,130,0003.0%Medical
Centessa Pharmaceuticals PLC Sponsored ADR stock logo
CNTA
Centessa Pharmaceuticals
$13,534,200$13,074,300 -49.1%1,030,0003.0%Medical
Pharvaris N.V. stock logo
PHVS
Pharvaris
$11,837,672$1,711,072 -12.6%672,5952.6%Medical
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
$11,608,240$11,608,240 New Holding266,0002.5%Medical
ABIVAX SA
$9,692,550$283,050 3.0%1,267,0002.1%SPONSORED ADS
DBV TECHNOLOGIES S A
$9,314,892$9,314,892 New Holding1,018,0212.0%SPONSORED ADS
Corbus Pharmaceuticals Holdings, Inc. stock logo
CRBP
Corbus Pharmaceuticals
$7,693,5000.0%1,115,0001.7%Medical
MoonLake Immunotherapeutics stock logo
MLTX
MoonLake Immunotherapeutics
$6,985,600$6,985,600 -50.0%148,0001.5%Medical
UNICYCIVE THERAPEUTICS INC
$4,770,000$4,770,000 New Holding1,000,0001.0%COM NEW
NEUROGENE INC
$4,529,8500.0%303,0001.0%COM
HELIX ACQUISITION CORP II
$2,662,5000.0%250,0000.6%CL A ORD SHS
MAZE THERAPEUTICS INC
$2,179,974$3,562,386 -62.0%177,6670.5%COM
KALARIS THERAPEUTICS INC
$961,200$323,070 -25.2%360,0000.2%COM
Erasca, Inc. stock logo
ERAS
Erasca
$889,000$5,634,730 -86.4%700,0000.2%Medical
NUVATION BIO INC
$300,518$52,994,471 -99.4%154,1120.1%*W EXP 02/10/202
Syndax Pharmaceuticals, Inc. stock logo
SNDX
Syndax Pharmaceuticals
$0$11,105,640 -100.0%00.0%Medical
Scholar Rock Holding Corporation stock logo
SRRK
Scholar Rock
$0$10,577,350 -100.0%00.0%Medical
Verastem, Inc. stock logo
VSTM
Verastem
$0$10,371,600 -100.0%00.0%Medical
Regulus Therapeutics Inc. stock logo
RGLS
Regulus Therapeutics
$0$8,114,883 -100.0%00.0%Medical
Viridian Therapeutics, Inc. stock logo
VRDN
Viridian Therapeutics
$0$6,066,000 -100.0%00.0%Medical
Unicycive Therapeutics, Inc. stock logo
UNCY
Unicycive Therapeutics
$0$5,749,000 -100.0%00.0%Medical
PERSPECTIVE THERAPEUTICS INC
$0$4,792,500 -100.0%00.0%COM NEW

Showing largest 100 holdings. View all holdings.
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