Samsara Biocapital, LLC Top Holdings and 13F Report (2025) About Samsara Biocapital, LLCInvestment ActivitySamsara Biocapital, LLC has $488.95 million in total holdings as of June 30, 2025.Samsara Biocapital, LLC owns shares of 29 different stocks, but just 7 companies or ETFs make up 80% of its holdings.Approximately 3.37% of the portfolio was purchased this quarter.About 10.91% of the portfolio was sold this quarter.This quarter, Samsara Biocapital, LLC has purchased 37 new stocks and bought additional shares in 1 stock.Samsara Biocapital, LLC sold shares of 8 stocks and completely divested from 11 stocks this quarter.Largest Holdings Scholar Rock $198,808,776Mineralys Therapeutics $76,781,613SEPTERNA INC $33,286,283KALARIS THERAPEUTICS INC $30,566,376NEUROGENE INC $25,671,049 Largest New Holdings this Quarter 05153U107 - Aura Biosciences $6,260,000 Holding008064206 - JADE BIOSCIENCES INC $5,306,318 Holding097702203 - BOLT BIOTHERAPEUTICS INC $302,671 Holding Largest Purchases this Quarter Aura Biosciences 1,000,000 shares (about $6.26M)JADE BIOSCIENCES INC 531,163 shares (about $5.31M)ALUMIS INC 1,534,872 shares (about $4.60M)BOLT BIOTHERAPEUTICS INC 52,456 shares (about $302.67K) Largest Sales this Quarter PALVELLA THERAPEUTICS INC NE 339,743 shares (about $7.66M)UPSTREAM BIO INC 623,915 shares (about $6.85M)Rhythm Pharmaceuticals 87,642 shares (about $5.54M)LENZ THERAPEUTICS INC 183,378 shares (about $5.37M)Zymeworks 356,367 shares (about $4.47M) Sector Allocation Over TimeMap of 500 Largest Holdings ofSamsara Biocapital, LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorSRRKScholar Rock$198,808,7760.0%5,612,89640.7%MedicalMLYSMineralys Therapeutics$76,781,6130.0%5,674,91615.7%MedicalSEPTERNA INC$33,286,2830.0%3,149,1286.8%COMKALARIS THERAPEUTICS INC$30,566,3760.0%11,448,0816.3%COMNEUROGENE INC$25,671,0490.0%1,717,1275.3%COMCARGO THERAPEUTICS INC$18,192,6390.0%4,415,6893.7%COMUPSTREAM BIO INC$15,846,676$6,850,587 ▼-30.2%1,443,2313.2%COMALUMIS INC$14,404,110$4,604,616 ▲47.0%4,801,3702.9%COMLENZ THERAPEUTICS INC$10,053,682$5,374,809 ▼-34.8%343,0122.1%COMPALVELLA THERAPEUTICS INC NE$7,657,807$7,657,807 ▼-50.0%339,7431.6%COMGOSSGossamer Bio$7,540,2300.0%6,130,2681.5%MedicalACLXArcellx$6,680,943$2,226,981 ▼-25.0%101,4571.4%MedicalAURAAura Biosciences$6,260,000$6,260,000 ▲New Holding1,000,0001.3%MedicalNKTXNkarta$6,254,9380.0%3,768,0351.3%MedicalAVADEL PHARMACEUTICALS PLC$5,978,210$2,584,403 ▼-30.2%675,5041.2%COM SHSJADE BIOSCIENCES INC$5,306,318$5,306,318 ▲New Holding531,1631.1%COM NEWZYMEZymeworks$3,894,265$4,472,406 ▼-53.5%310,3000.8%MedicalRYTMRhythm Pharmaceuticals$3,189,578$5,538,097 ▼-63.5%50,4760.7%MedicalVTV THERAPEUTICS INC$3,101,7600.0%206,7840.6%CL A NEWCONTINEUM THERAPEUTICS INC$2,337,6000.0%588,8160.5%CL ASURROZEN INC$2,158,1160.0%241,4000.4%COM NEWSTROSutro Biopharma$1,568,3060.0%2,196,8140.3%MedicalTNGXTango Therapeutics$1,075,200$2,150,400 ▼-66.7%210,0000.2%MedicalHLVXHilleVax$795,2780.0%399,6370.2%MedicalTERNTerns Pharmaceuticals$754,7580.0%202,3480.2%MedicalARTIVA BIOTHERAPEUTICS INC$440,4160.0%291,6660.1%COMBOLT BIOTHERAPEUTICS INC$302,671$302,671 ▲New Holding52,4560.1%COM NEWNUVATION BIO INC$35,9870.0%133,3330.0%*W EXP 02/10/202SRZNWSurrozen$1,8100.0%99,9990.0%MedicalSLRNAcelyrin$0$6,231,864 ▼-100.0%00.0%MedicalONKURE THERAPEUTICS INC$0$3,543,867 ▼-100.0%00.0%COM CL AABIVAX SA$0$2,656,250 ▼-100.0%00.0%SPONSORED ADSINZYInozyme Pharma$0$1,421,875 ▼-100.0%00.0%MedicalPRMEPrime Medicine$0$806,404 ▼-100.0%00.0%MedicalLPTXLeap Therapeutics$0$745,162 ▼-100.0%00.0%MedicalBOLTBolt Biotherapeutics$0$419,661 ▼-100.0%00.0%MedicalCURIS INC$0$390,480 ▼-100.0%00.0%COMLYRALyra Therapeutics$0$175,573 ▼-100.0%00.0%MedicalKRONKronos Bio$0$64,458 ▼-100.0%00.0%MedicalALLKAllakos$0$39,167 ▼-100.0%00.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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