Samsara Biocapital, LLC Top Holdings and 13F Report (2025) About Samsara Biocapital, LLCInvestment ActivitySamsara Biocapital, LLC has $560.81 million in total holdings as of March 31, 2025.Samsara Biocapital, LLC owns shares of 37 different stocks, but just 8 companies or ETFs make up 80% of its holdings.Approximately 18.99% of the portfolio was purchased this quarter.About 10.81% of the portfolio was sold this quarter.This quarter, Samsara Biocapital, LLC has purchased 43 new stocks and bought additional shares in 2 stocks.Samsara Biocapital, LLC sold shares of 8 stocks and completely divested from 8 stocks this quarter.Largest Holdings Scholar Rock $180,454,606KALARIS THERAPEUTICS INC $91,928,090Mineralys Therapeutics $90,117,666NEUROGENE INC $20,107,557ALUMIS INC $20,056,298 Largest New Holdings this Quarter 482929106 - KALARIS THERAPEUTICS INC $91,928,090 Holding86889P208 - SURROZEN INC $2,814,724 Holding Largest Purchases this Quarter KALARIS THERAPEUTICS INC 11,448,081 shares (about $91.93M)Mineralys Therapeutics 600,000 shares (about $9.53M)SURROZEN INC 241,400 shares (about $2.81M)SEPTERNA INC 380,608 shares (about $2.20M) Largest Sales this Quarter LENZ THERAPEUTICS INC 460,591 shares (about $11.84M)Arcellx 118,365 shares (about $7.76M)Zymeworks 333,333 shares (about $3.97M)ABIVAX SA 425,000 shares (about $2.66M)Rhythm Pharmaceuticals 34,529 shares (about $1.83M) Sector Allocation Over TimeMap of 500 Largest Holdings ofSamsara Biocapital, LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorSRRKScholar Rock$180,454,6060.0%5,612,89632.2%MedicalKALARIS THERAPEUTICS INC$91,928,090$91,928,090 ▲New Holding11,448,08116.4%COMMLYSMineralys Therapeutics$90,117,666$9,528,000 ▲11.8%5,674,91616.1%MedicalNEUROGENE INC$20,107,5570.0%1,717,1273.6%COMALUMIS INC$20,056,2980.0%3,266,4983.6%COMPALVELLA THERAPEUTICS INC NE$19,018,8130.0%679,4863.4%COMSEPTERNA INC$18,233,451$2,203,720 ▲13.7%3,149,1283.3%COMCARGO THERAPEUTICS INC$17,971,8540.0%4,415,6893.2%COMLENZ THERAPEUTICS INC$13,533,487$11,841,795 ▼-46.7%526,3902.4%COMUPSTREAM BIO INC$12,650,934$918,000 ▼-6.8%2,067,1462.3%COMACLXArcellx$8,874,106$7,764,744 ▼-46.7%135,2761.6%MedicalZYMEZymeworks$7,940,004$3,969,996 ▼-33.3%666,6671.4%MedicalAVADEL PHARMACEUTICALS PLC$7,575,7360.0%967,5271.4%COM SHSRYTMRhythm Pharmaceuticals$7,316,110$1,829,001 ▼-20.0%138,1181.3%MedicalNKTXNkarta$6,933,1840.0%3,768,0351.2%MedicalGOSSGossamer Bio$6,743,2950.0%6,130,2681.2%MedicalSLRNAcelyrin$6,231,8640.0%2,523,0221.1%MedicalCONTINEUM THERAPEUTICS INC$4,109,9360.0%588,8160.7%CL AVTV THERAPEUTICS INC$3,581,4990.0%206,7840.6%CL A NEWONKURE THERAPEUTICS INC$3,543,8670.0%824,1550.6%COM CL ASURROZEN INC$2,814,724$2,814,724 ▲New Holding241,4000.5%COM NEWABIVAX SA$2,656,250$2,656,250 ▼-50.0%425,0000.5%SPONSORED ADSSTROSutro Biopharma$1,429,2470.0%2,196,8140.3%MedicalINZYInozyme Pharma$1,421,8750.0%1,562,5000.3%MedicalARTIVA BIOTHERAPEUTICS INC$874,9980.0%291,6660.2%COMTNGXTango Therapeutics$863,1000.0%630,0000.2%MedicalPRMEPrime Medicine$806,4040.0%405,2280.1%MedicalLPTXLeap Therapeutics$745,1620.0%2,442,3520.1%MedicalHLVXHilleVax$579,4740.0%399,6370.1%MedicalTERNTerns Pharmaceuticals$558,4800.0%202,3480.1%MedicalBOLTBolt Biotherapeutics$419,6610.0%1,049,1530.1%MedicalCURIS INC$390,480$25,773 ▼-6.2%185,9430.1%COMLYRALyra Therapeutics$175,573$72,693 ▼-29.3%1,390,1300.0%MedicalKRONKronos Bio$64,4580.0%78,1310.0%MedicalNUVATION BIO INC$42,6670.0%133,3330.0%*W EXP 02/10/202ALLKAllakos$39,1670.0%172,0890.0%MedicalSRZNWSurrozen$3,0000.0%99,9990.0%MedicalJASPER THERAPEUTICS INC$0$12,499,646 ▼-100.0%00.0%COM NEWACRSAclaris Therapeutics$0$5,914,949 ▼-100.0%00.0%MedicalELYMEliem Therapeutics$0$4,696,405 ▼-100.0%00.0%MedicalVRNAVerona Pharma$0$4,533,705 ▼-100.0%00.0%MedicalDAWNDay One Biopharmaceuticals$0$1,866,532 ▼-100.0%00.0%MedicalIMTXImmatics$0$1,407,780 ▼-100.0%00.0%MedicalJANXJanux Therapeutics$0$603,021 ▼-100.0%00.0%MedicalALVRAlloVir$0$34,581 ▼-100.0%00.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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