NASDAQ:TNGX Tango Therapeutics (TNGX) Stock Price, News & Analysis $21.62 +0.54 (+2.56%) Closing price 04:00 PM EasternExtended Trading$21.14 -0.48 (-2.22%) As of 04:42 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Tango Therapeutics Stock (NASDAQ:TNGX) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Tango Therapeutics alerts:Sign Up Key Stats Today's Range$20.67▼$22.2450-Day Range$16.50▼$27.7752-Week Range$1.72▼$28.41Volume2.58 million shsAverage Volume3.28 million shsMarket Capitalization$3.13 billionP/E RatioN/ADividend YieldN/APrice Target$32.27Consensus RatingModerate Buy Company Overview Tango Therapeutics is a clinical-stage biotechnology company dedicated to developing precision medicines that exploit genetic vulnerabilities in cancer cells. Leveraging a proprietary synthetic lethality platform, the company identifies and targets tumor-specific dependencies in DNA damage response and related pathways. By focusing on tumor cell collateral sensitivities, Tango aims to bring differentiated small-molecule therapies to patients with genetic alterations that confer increased susceptibility to targeted inhibition. The company’s lead pipeline comprises several early-stage programs, including inhibitors designed to selectively disable DNA repair proteins in tumor cells while sparing normal tissues. Tango has entered strategic collaborations with major pharmaceutical partners to advance these programs, most notably a multi-asset agreement with GSK to discover and develop DNA damage response inhibitors and a partnership with Merck focused on novel synthetic lethal targets in oncology. These alliances provide access to additional computational tools, screening libraries and global development expertise. Founded in 2019 as a spin-out from Dana-Farber Cancer Institute and Harvard Medical School, Tango Therapeutics is headquartered in Cambridge, Massachusetts, near one of the world’s leading biopharma clusters. The management team combines scientific founders with broad drug development experience, enabling the company to rapidly translate genetic insights into translational programs. Tango has assembled an advisory board of academic and industry experts to guide target selection and clinical strategy. With its concentrated focus on synthetic lethality, Tango Therapeutics seeks to address unmet needs in solid tumors and hematologic cancers driven by specific genetic lesions. The company is advancing its pipeline through IND-enabling studies and early clinical trials, aiming to validate its approach of pairing genomic profiling with highly selective therapies. Tango’s platform is designed to uncover novel treatment modalities that could extend the benefits of precision oncology to patient populations beyond those served by current standard-of-care agents.AI Generated. May Contain Errors. Read More Tango Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks54th Percentile Overall ScoreTNGX MarketRank™: Tango Therapeutics scored higher than 54% of companies evaluated by MarketBeat, and ranked 452nd out of 856 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.3 / 5Analyst RatingModerate Buy Consensus RatingTango Therapeutics has received a consensus rating of Moderate Buy. The company's average rating score is 2.64, and is based on no strong buy ratings, 10 buy ratings, 3 hold ratings, and 1 sell rating.Upside PotentialTango Therapeutics has a consensus price target of $32.27, representing about 49.3% upside from its current price of $21.62.Amount of Analyst CoverageTango Therapeutics has been the subject of 12 research reports in the past 90 days, demonstrating strong analyst interest in this stock.Read more about Tango Therapeutics' stock forecast and price target. Earnings and Valuation0.0 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Tango Therapeutics are expected to decrease in the coming year, from ($1.34) to ($1.51) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Tango Therapeutics is -26.05, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Tango Therapeutics is -26.05, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioTango Therapeutics has a P/B Ratio of 7.98. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Tango Therapeutics' valuation and earnings. Short Interest1.0 / 5Short Interest LevelBearish Percentage of Shares Shorted28.36% of the float of Tango Therapeutics has been sold short.Short Interest Ratio / Days to CoverTango Therapeutics has a short interest ratio ("days to cover") of 12.51, which indicates bearish sentiment.Change versus previous monthShort interest in Tango Therapeutics has recently decreased by 4.96%, indicating that investor sentiment is improving. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldTango Therapeutics does not currently pay a dividend.Dividend GrowthTango Therapeutics does not have a long track record of dividend growth. News and Social Media2.7 / 5News Sentiment0.38 News SentimentTango Therapeutics has a news sentiment score of 0.38. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This news sentiment score is similar to the average news sentiment of Medical companies.News Coverage This WeekMarketBeat has tracked 9 news articles for Tango Therapeutics this week, compared to 3 articles on an average week.Search Interest12 people have searched for TNGX on MarketBeat in the last 30 days. This is an increase of 71% compared to the previous 30 days. Company Ownership1.7 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Tango Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $3,346,181.00 in company stock.Percentage Held by Insiders6.50% of the stock of Tango Therapeutics is held by insiders.Percentage Held by Institutions78.99% of the stock of Tango Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Tango Therapeutics' insider trading history. 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Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. TNGX Stock News HeadlinesTango Therapeutics, Inc. (NASDAQ:TNGX) Receives Consensus Rating of "Moderate Buy" from BrokeragesMay 20 at 4:19 AM | americanbankingnews.comPiper Sandler downgrades Tango Therapeutics (TNGX)May 17, 2026 | msn.comI was right about SpaceXJeff Brown predicted Bitcoin before it climbed as high as 52,400%, Tesla before 2,150%, and Nvidia before 32,000%. Now he says SpaceX is shaping up to be the biggest IPO of the decade - and three key milestones just confirmed it. In the past 21 days: SpaceX crossed 10,000 active satellites, Elon filed confidential IPO paperwork with the SEC, and another rocket launched 25 more satellites. Two-thirds of every satellite in orbit now belongs to one company. The public filing could drop any day.May 21 at 1:00 AM | Brownstone Research (Ad)Tango Therapeutics (NASDAQ:TNGX) Stock Price Down 14.4% - What's Next?May 17, 2026 | americanbankingnews.comTNGX stock crashes 20% after reporting $0 revenue in Q1 — but analysts still see massive upsideMay 15, 2026 | msn.comJefferies downgrades Tango Therapeutics (TNGX)May 15, 2026 | msn.comTango Therapeutics (NASDAQ:TNGX) Given New $33.00 Price Target at WedbushMay 15, 2026 | americanbankingnews.comTango Therapeutics (NASDAQ:TNGX) Insider Adam Crystal Sells 27,000 SharesMay 6, 2026 | insidertrades.comSee More Headlines TNGX Stock Analysis - Frequently Asked Questions How have TNGX shares performed this year? Tango Therapeutics' stock was trading at $8.86 at the beginning of 2026. Since then, TNGX stock has increased by 144.0% and is now trading at $21.62. How were Tango Therapeutics' earnings last quarter? Tango Therapeutics, Inc. (NASDAQ:TNGX) issued its earnings results on Wednesday, May, 13th. The company reported ($0.32) EPS for the quarter, hitting the consensus estimate of ($0.32). Tango Therapeutics had a negative trailing twelve-month return on equity of 41.54% and a negative net margin of 151.15%. When did Tango Therapeutics IPO? Tango Therapeutics (TNGX) raised $145 million in an IPO on Thursday, September 3rd 2020. The company issued 14,500,000 shares at a price of $10.00 per share. Who are Tango Therapeutics' major shareholders? Tango Therapeutics' top institutional investors include TRV GP IV LLC (4.42%), Siren L.L.C. (3.92%), Janus Henderson Group PLC (1.66%) and Candriam S.C.A. (0.88%). Insiders that own company stock include Rock Ventures Iv LP Third, Boxer Capital, Llc, Boxer Capital Management, Llc, Barbara Weber, Mva Investors, Llc, Daniella Beckman, Adam Crystal, Douglas Barry and Mace Rothenberg. View institutional ownership trends. How do I buy shares of Tango Therapeutics? Shares of TNGX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Tango Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Tango Therapeutics investors own include NVIDIA (NVDA), Meta Platforms (META), Advanced Micro Devices (AMD), Broadcom (AVGO), Palo Alto Networks (PANW), Adobe (ADBE) and ServiceNow (NOW). Company Calendar Last Earnings5/13/2026Today5/21/2026Next Earnings (Estimated)8/04/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (10m+) 1-Year History May 25 Aug 25 Nov 25 Feb 26 May 26 TNGX's financial health is in the Green zone, according to TradeSmith. TNGX has been in this zone for over 10 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:TNGX CIK1819133 Webwww.tangotx.com Phone857-320-4900FaxN/AEmployees90Year Founded2017Price Target and Rating Average Price Target for Tango Therapeutics$32.27 High Price Target$55.00 Low Price Target$14.00 Potential Upside/Downside+49.3%Consensus RatingModerate Buy Rating Score (0-4)2.64 Research Coverage14 Analysts Profitability EPS (Trailing Twelve Months)($0.83) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$101.59 million Net Margins-151.15% Pretax Margin-188.20% Return on Equity-41.54% Return on Assets-33.44% Debt Debt-to-Equity RatioN/A Current Ratio27.38 Quick Ratio27.38 Sales & Book Value Annual Sales$62.38 million Price / Sales50.13 Cash FlowN/A Price / Cash FlowN/A Book Value$2.71 per share Price / Book7.98Miscellaneous Outstanding Shares144,650,000Free Float135,246,000Market Cap$3.13 billion OptionableOptionable Beta1.22 Social Links The Best Nuclear Energy Stocks to BuyNuclear energy is entering a new growth cycle as rising power demand, expanding data centers, and renewed policy support bring the sector back into focus. 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