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NASDAQ:RYTM

Rhythm Pharmaceuticals (RYTM) Stock Price, News & Analysis

Rhythm Pharmaceuticals logo
$86.61 -3.21 (-3.57%)
Closing price 04:00 PM Eastern
Extended Trading
$86.66 +0.05 (+0.06%)
As of 07:50 PM Eastern
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About Rhythm Pharmaceuticals Stock (NASDAQ:RYTM)

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Key Stats

Today's Range
$86.35
▼
$90.51
50-Day Range
$86.61
▼
$117.60
52-Week Range
$74.50
▼
$122.20
Volume
622,979 shs
Average Volume
835,300 shs
Market Capitalization
$5.94 billion
P/E Ratio
N/A
Dividend Yield
N/A
Price Target
$142.56
Consensus Rating
Moderate Buy

Company Overview

Rhythm Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing and commercializing medicines for rare genetic diseases of obesity and other disorders involving the melanocortin-4 receptor (MC4R) pathway. The company’s research is centered on conditions in which genetic defects disrupt the body’s regulation of appetite, hunger and energy expenditure.

Rhythm’s lead product is IMCIVREE (setmelanotide), an MC4R agonist designed to restore signaling in the brain’s melanocortin pathway. The therapy is approved in the United States for chronic weight management in adults and children with obesity caused by certain genetic deficiencies, including POMC, PCSK1 and LEPR deficiencies, as well as Bardet-Biedl syndrome. Setmelanotide is also authorized in the European Union for certain patients with genetically confirmed rare forms of obesity.

Founded in 2008 and headquartered in Boston, Massachusetts, Rhythm serves patients through commercial and medical operations in the United States and international markets. The company continues to study setmelanotide in additional rare genetic obesity populations and develop other potential treatments targeting the MC4R pathway. David Meeker has served as Rhythm’s president and chief executive officer.

AI Generated. May Contain Errors.

Rhythm Pharmaceuticals Stock Analysis - MarketRank™

See Top-Rated MarketRank™ Stocks
51st Percentile Overall Score

RYTM MarketRank™: 
2.54045520326 of 5 stars

Rhythm Pharmaceuticals scored higher than 51% of companies evaluated by MarketBeat, and ranked 537th out of 877 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

  • Consensus Rating

    Rhythm Pharmaceuticals has received a consensus rating of Moderate Buy. The company's average rating score is 2.76, and is based on no strong buy ratings, 17 buy ratings, 3 hold ratings, and 1 sell rating.

  • Upside Potential

    Rhythm Pharmaceuticals has a consensus price target of $142.56, representing about 64.6% upside from its current price of $86.61.

  • Amount of Analyst Coverage

    Rhythm Pharmaceuticals has been the subject of 9 research reports in the past 90 days, demonstrating strong analyst interest in this stock.

  • Read more about Rhythm Pharmaceuticals' stock forecast and price target.
  • Earnings Growth

    Earnings for Rhythm Pharmaceuticals are expected to grow in the coming year, from ($2.86) to ($0.43) per share.

  • Price to Earnings Ratio vs. the Market

    The P/E ratio of Rhythm Pharmaceuticals is -27.85, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Earnings Ratio vs. Sector

    The P/E ratio of Rhythm Pharmaceuticals is -27.85, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Book Value per Share Ratio

    Rhythm Pharmaceuticals has a P/B Ratio of 41.64. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.

  • Read more about Rhythm Pharmaceuticals' valuation and earnings.
  • Percentage of Shares Shorted

    16.70% of the float of Rhythm Pharmaceuticals has been sold short.
  • Short Interest Ratio / Days to Cover

    Rhythm Pharmaceuticals has a short interest ratio ("days to cover") of 14.14, which indicates bearish sentiment.
  • Change versus previous month

    Short interest in Rhythm Pharmaceuticals has recently increased by 4.66%, indicating that investor sentiment is decreasing.
  • Dividend Yield

    Rhythm Pharmaceuticals does not currently pay a dividend.

  • Dividend Growth

    Rhythm Pharmaceuticals does not have a long track record of dividend growth.

  • News Sentiment

    Rhythm Pharmaceuticals has a news sentiment score of 0.79. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This news sentiment score is similar to the average news sentiment of Healthcare companies.
  • News Coverage This Week

    MarketBeat has tracked 3 news articles for Rhythm Pharmaceuticals this week, compared to 5 articles on an average week.
  • Search Interest

    2 people have searched for RYTM on MarketBeat in the last 30 days. This is an increase of 100% compared to the previous 30 days.
  • MarketBeat Follows

    3 people have added Rhythm Pharmaceuticals to their MarketBeat watchlist in the last 30 days. This is an increase of 200% compared to the previous 30 days.
  • Insider Buying vs. Insider Selling

    In the past three months, Rhythm Pharmaceuticals insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $28,796,497.00 in company stock.

  • Percentage Held by Insiders

    5.90% of the stock of Rhythm Pharmaceuticals is held by insiders.

  • Percentage Held by Institutions

    Rhythm Pharmaceuticals has minimal institutional ownership at this time.

  • Read more about Rhythm Pharmaceuticals' insider trading history.
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RYTM Stock News Headlines

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Rhythm Pops on Health Canada Nod
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RYTM Stock Analysis - Frequently Asked Questions

Rhythm Pharmaceuticals' stock was trading at $107.04 at the beginning of 2026. Since then, RYTM shares have decreased by 19.1% and is now trading at $86.61.

Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM) issued its quarterly earnings results on Tuesday, August, 4th. The company reported ($0.73) EPS for the quarter, beating analysts' consensus estimates of ($0.81) by $0.08. The business's revenue for the quarter was up 46.9% compared to the same quarter last year.
Read the conference call transcript
.

Rhythm Pharmaceuticals (RYTM) raised $106 million in an IPO on Thursday, October 5th 2017. The company issued 7,050,000 shares at a price of $14.00-$16.00 per share. Morgan Stanley, BofA Merrill Lynch and Cowen served as the underwriters for the IPO and Needham was co-manager.

Top institutional shareholders of Rhythm Pharmaceuticals include GAMMA Investing LLC. Insiders that own company stock include David P Meeker, Hunter C Smith, Yann Mazabraud, Jennifer Kayden Lee, Pamela J Cramer, Joseph Shulman, Lynn A Tetrault, Jennifer L Good, Alastair Garfield and Christopher Paul German.
View institutional ownership trends
.

Shares of RYTM stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

Based on aggregate information from My MarketBeat watchlists, some other companies that Rhythm Pharmaceuticals investors own include NVIDIA (NVDA), Advanced Micro Devices (AMD), Eli Lilly and Company (LLY), Palantir Technologies (PLTR), Tesla (TSLA), Viking Therapeutics (VKTX) and NIO (NIO).

Company Calendar

Last Earnings
8/04/2026
Today
10/13/2026
Next Earnings (Estimated)
11/03/2026
Fiscal Year End
12/31/2026

Industry, Sector and Symbol

Stock Exchange
NASDAQ
Industry
Biotechnology
Sub-Industry
Biotechnology
Current Symbol
NASDAQ:RYTM
CIK
1649904
Employees
414
Year Founded
2008

Price Target and Rating

High Price Target
$160.00
Low Price Target
$120.00
Potential Upside/Downside
+64.6%
Consensus Rating
Moderate Buy
Rating Score (0-4)
2.76
Research Coverage
21 Analysts

Profitability

EPS (Trailing Twelve Months)
($3.11)
Trailing P/E Ratio
N/A
Forward P/E Ratio
N/A
P/E Growth
N/A
Net Income
-$196.54 million
Net Margins
-85.59%
Pretax Margin
-85.14%
Return on Equity
-159.87%
Return on Assets
-44.00%

Debt

Debt-to-Equity Ratio
N/A
Current Ratio
3.45
Quick Ratio
3.20

Sales & Book Value

Annual Sales
$189.76 million
Price / Sales
31.28
Cash Flow
N/A
Price / Cash Flow
N/A
Book Value
$2.08 per share
Price / Book
41.64

Miscellaneous

Outstanding Shares
68,530,000
Free Float
64,490,000
Market Cap
$5.94 billion
Optionable
Optionable
Beta
2.01

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This page (NASDAQ:RYTM) was last updated on 10/13/2026 by MarketBeat.com Staff.
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