| 06/25/2026 5:08 PM | MCGIRR DAVID W J (1219023) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/25/2026 5:09 PM | JEAN CHRISTOPHE (1378435) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/25/2026 5:01 PM | GOOD JENNIFER L (1229245) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/25/2026 5:03 PM | Arbuckle Stuart A (1557290) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/25/2026 5:06 PM | Rhythm Pharmaceuticals (1649904) Issuer TETRAULT LYNN A. (1645512) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/25/2026 3:46 PM | Rhythm Pharmaceuticals (1649904) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 06/24/2026 3:15 PM | Rhythm Pharmaceuticals (1649904) Issuer TETRAULT LYNN A. (1645512) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/22/2026 3:49 PM | Rhythm Pharmaceuticals (1649904) Subject TETRAULT LYNN A. (1645512) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 06/15/2026 3:07 PM | Rhythm Pharmaceuticals (1649904) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 05/20/2026 3:15 PM | Rhythm Pharmaceuticals (1649904) Issuer Smith Hunter C (1636385) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 05/05/2026 3:18 PM | Rhythm Pharmaceuticals (1649904) Filer | Form DEFA14A | |
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| 05/05/2026 6:48 AM | Rhythm Pharmaceuticals (1649904) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 04/30/2026 11:56 AM | Rhythm Pharmaceuticals (1649904) Subject VANGUARD CAPITAL MANAGEMENT LLC (2100119) Filed by | Form SCHEDULE 13G | |
| 04/03/2026 4:34 PM | Popovits Kimberly J (1333482) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 3 Initial statement of beneficial ownership of securities | |
| 04/03/2026 4:35 PM | Popovits Kimberly J (1333482) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/03/2026 4:36 PM | Mazabraud Yann (1774702) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/03/2026 2:06 PM | Rhythm Pharmaceuticals (1649904) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 03/27/2026 10:33 AM | Rhythm Pharmaceuticals (1649904) Subject VANGUARD GROUP INC (102909) Filed by | Form SCHEDULE 13G/A | |
| 03/20/2026 8:20 AM | Rhythm Pharmaceuticals (1649904) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 03/16/2026 3:11 PM | Mathers Edward T (1328625) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/06/2026 3:51 PM | German Christopher Paul (1260835) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/04/2026 7:22 PM | Mazabraud Yann (1774702) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/04/2026 3:40 PM | Mathers Edward T (1328625) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/03/2026 6:45 PM | German Christopher Paul (1260835) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/02/2026 7:56 PM | Rhythm Pharmaceuticals (1649904) Issuer Smith Hunter C (1636385) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/02/2026 5:01 AM | Rhythm Pharmaceuticals (1649904) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 02/26/2026 4:37 PM | Rhythm Pharmaceuticals (1649904) Filer | Form S-3ASR | |
| 02/26/2026 4:16 PM | Rhythm Pharmaceuticals (1649904) Filer | Form S-8 Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans | |
| 02/26/2026 6:30 AM | Rhythm Pharmaceuticals (1649904) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 02/19/2026 8:02 PM | Rhythm Pharmaceuticals (1649904) Issuer Smith Hunter C (1636385) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/13/2026 4:48 PM | German Christopher Paul (1260835) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/13/2026 4:49 PM | Lee Jennifer Kayden (1801372) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/13/2026 4:50 PM | Mazabraud Yann (1774702) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/13/2026 4:52 PM | Meeker David P (1385155) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/13/2026 4:53 PM | Rhythm Pharmaceuticals (1649904) Issuer Shulman Joseph (1909855) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/13/2026 4:47 PM | Garfield Alastair (2027261) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/13/2026 4:45 PM | Cramer Pamela J. (1873517) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/12/2026 7:56 PM | Rhythm Pharmaceuticals (1649904) Issuer Smith Hunter C (1636385) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/06/2026 5:38 PM | Rhythm Pharmaceuticals (1649904) Issuer Smith Hunter C (1636385) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/03/2026 3:35 PM | Rhythm Pharmaceuticals (1649904) Issuer Shulman Joseph (1909855) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/03/2026 3:36 PM | Rhythm Pharmaceuticals (1649904) Issuer Smith Hunter C (1636385) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
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| 02/03/2026 3:38 PM | Mazabraud Yann (1774702) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 01/30/2026 1:43 PM | Rhythm Pharmaceuticals (1649904) Subject VANGUARD GROUP INC (102909) Filed by | Form SCHEDULE 13G/A | |
| 01/16/2026 6:50 AM | Rhythm Pharmaceuticals (1649904) Filer | Form S-8 Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans | |
| 01/09/2026 8:06 AM | Rhythm Pharmaceuticals (1649904) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 12/19/2025 3:05 PM | Rhythm Pharmaceuticals (1649904) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 12/11/2025 3:25 PM | Cramer Pamela J. (1873517) Reporting Rhythm Pharmaceuticals (1649904) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 12/11/2025 6:50 AM | Rhythm Pharmaceuticals (1649904) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 11/24/2025 3:15 PM | Cramer Pamela J. (1873517) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 11/20/2025 3:23 PM | Cramer Pamela J. (1873517) Reporting Rhythm Pharmaceuticals (1649904) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/12/2025 3:30 PM | Cramer Pamela J. (1873517) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 11/07/2025 3:38 PM | Cramer Pamela J. (1873517) Reporting Rhythm Pharmaceuticals (1649904) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/07/2025 7:09 AM | Rhythm Pharmaceuticals (1649904) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 11/04/2025 6:05 AM | Rhythm Pharmaceuticals (1649904) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 11/03/2025 3:30 PM | Rhythm Pharmaceuticals (1649904) Issuer Shulman Joseph (1909855) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 10/30/2025 3:44 PM | Rhythm Pharmaceuticals (1649904) Issuer Shulman Joseph (1909855) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 10/30/2025 3:16 PM | Rhythm Pharmaceuticals (1649904) Subject Shulman Joseph (1909855) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/30/2025 2:50 PM | Rhythm Pharmaceuticals (1649904) Subject VANGUARD GROUP INC (102909) Filed by | Form SCHEDULE 13G/A | |
| 10/28/2025 3:17 PM | Rhythm Pharmaceuticals (1649904) Subject Shulman Joseph (1909855) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/16/2025 3:20 PM | Rhythm Pharmaceuticals (1649904) Subject Shulman Joseph (1909855) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 09/04/2025 3:30 PM | Rhythm Pharmaceuticals (1649904) Issuer Shulman Joseph (1909855) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 09/02/2025 3:41 PM | Rhythm Pharmaceuticals (1649904) Subject Shulman Joseph (1909855) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 08/25/2025 7:59 PM | Rhythm Pharmaceuticals (1649904) Issuer Shulman Joseph (1909855) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 08/21/2025 3:45 PM | Rhythm Pharmaceuticals (1649904) Subject Shulman Joseph (1909855) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 08/14/2025 5:47 PM | German Christopher Paul (1260835) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 08/14/2025 5:48 PM | Rhythm Pharmaceuticals (1649904) Issuer Smith Hunter C (1636385) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 08/14/2025 5:04 PM | RA CAPITAL MANAGEMENT, L.P. (1346824) Filed by Rhythm Pharmaceuticals (1649904) Subject | Form SCHEDULE 13G/A | |
| 08/14/2025 12:28 PM | PRIMECAP MANAGEMENT CO/CA/ (763212) Filed by Rhythm Pharmaceuticals (1649904) Subject | Form SCHEDULE 13G/A | |
| 08/13/2025 5:32 PM | Rhythm Pharmaceuticals (1649904) Issuer Shulman Joseph (1909855) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 08/11/2025 3:22 PM | Rhythm Pharmaceuticals (1649904) Subject Shulman Joseph (1909855) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 08/05/2025 6:05 AM | Rhythm Pharmaceuticals (1649904) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 07/29/2025 5:56 PM | Cramer Pamela J. (1873517) Reporting Rhythm Pharmaceuticals (1649904) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |