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Rhythm Pharmaceuticals (RYTM) Institutional Ownership

Rhythm Pharmaceuticals logo
$90.78 +1.14 (+1.27%)
Closing price 04:00 PM Eastern
Extended Trading
$90.80 +0.02 (+0.02%)
As of 05:26 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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Institutional Ownership Changes (13F Filings) for Rhythm Pharmaceuticals (NASDAQ:RYTM)

Number of
Institutional Buyers
(last 12 months)
176
Total
Institutional Inflows
(last 12 months)
$2.81B
Number of
Institutional Sellers
(last 12 months)
95
Total
Institutional Outflows
(last 12 months)
$45.22B
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RYTM Institutional Buying and Selling by Quarter

Rhythm Pharmaceuticals Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
10/9/2026GAMMA Investing LLC492$47K0.0%+35.2%0.001%
9/29/2026Cim Investment Management Inc.3,209$356K0.1%+7.2%0.005%
9/9/2026Opaleye Management Inc.122,500$13.60M1.2%-0.4%0.179%
9/9/2026First Light Asset Management LLC85,765$9.52M0.6%-1.6%0.125%
9/9/2026Squarepoint Ops LLC422,921$46.96M0.1%+60.8%0.617%
9/8/2026Arizona State Retirement System15,073$1.67M0.0%-3.3%0.022%
9/8/2026Nykredit A S2,525$280K0.0%N/A0.004%
8/26/2026Amundi3,422$380K0.0%-14.8%0.005%
8/25/2026VIRGINIA RETIREMENT SYSTEMS ET Al3,700$411K0.0%N/A0.005%
8/21/2026Braidwell LP381,128$42.32M1.6%+22.7%0.556%
8/21/2026Nykredit A S2,525$280K0.0%N/A0.004%
8/19/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC514,850$57.16M0.0%-4.9%0.751%
8/19/2026Toth Financial Advisory Corp7,800$866K0.1%-22.0%0.011%
8/19/2026Wellington Management Group LLP488,747$54.27M0.0%+78.5%0.713%
8/18/2026Centaurus Financial Inc.2,454$272K0.0%N/A0.004%
8/17/2026Capstone Investment Advisors LLC3,005$334K0.0%N/A0.004%
8/17/2026Bank of America Corp DE325,470$36.14M0.0%N/A0.475%
8/15/2026Man Group plc50,788$5.64M0.0%N/A0.074%
8/15/2026Jupiter Topco LLC925,490$102.75M0.0%N/A1.350%
8/14/2026ADAR1 Capital Management LLC136,158$15.12M0.7%N/A0.199%
8/14/2026EFG International AG33,577$3.73M0.1%N/A0.049%
8/14/2026Primecap Management Co. CA3,168,853$351.84M0.2%N/A4.624%
8/14/2026Canada Pension Plan Investment Board47,400$5.26M0.0%N/A0.069%
8/14/2026Nicholas Investment Partners LP139,270$15.46M0.9%N/A0.203%
8/14/2026Legal & General Group Plc43,908$4.88M0.0%N/A0.064%
8/14/2026The Manufacturers Life Insurance Company57,170$6.35M0.0%N/A0.083%
8/14/2026Nan Fung Group Holdings Ltd49,120$5.45M0.0%N/A0.072%
8/14/2026Algert Global LLC83,431$9.26M0.1%+42.6%0.122%
8/13/2026Connor Clark & Lunn Investment Management Ltd.135,867$15.09M0.0%N/A0.198%
8/11/2026Blue Owl Capital Holdings LP61,455$6.82M1.0%N/A0.090%
8/11/2026E Fund Management Co. Ltd.4,751$528K0.0%N/A0.007%
8/7/2026BlackRock Inc.6,156,902$683.60M0.0%N/A8.984%
8/7/2026Deutsche Bank AG115,232$12.79M0.0%N/A0.168%
8/6/2026Global Retirement Partners LLC460$51K0.0%N/A0.001%
8/6/2026Bank of New York Mellon Corp394,044$43.75M0.0%N/A0.575%
8/6/2026State of Wyoming6,354$705K0.1%N/A0.009%
8/3/2026Walleye Capital LLC5,996$666K0.0%N/A0.009%
7/10/2026Wedge Capital Management L L P NC23,422$2.60M0.0%-4.5%0.034%
7/10/2026E. Ohman J or Asset Management AB5,523$613K0.0%+25.3%0.008%
7/10/2026Handelsbanken Fonder AB18,921$2.10M0.0%+8.0%0.028%
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7/8/2026Assenagon Asset Management S.A.186,491$20.71M0.0%N/A0.272%
7/7/2026GAMMA Investing LLC364$40K0.0%+36.3%0.001%
7/7/2026Avior Wealth Management LLC5,440$604K0.0%+17.0%0.008%
5/29/2026Perceptive Advisors LLC2,373,795$206.45M4.0%-6.8%3.464%
5/19/2026Bank of America Corp DE628,667$54.68M0.0%+180.0%0.917%
5/19/2026Janus Henderson Group PLC918,153$79.89M0.0%-18.5%1.340%
5/18/2026ADAR1 Capital Management LLC211,450$18.39M1.1%+311.8%0.309%
5/18/2026Amundi4,017$349K0.0%N/A0.006%
5/18/2026EverSource Wealth Advisors LLC549$48K0.0%+106.4%0.001%
5/18/2026California State Teachers Retirement System65,806$5.72M0.0%+22.9%0.096%
5/18/2026Rock Springs Capital Management LP689,748$59.99M3.5%-0.8%1.006%
5/18/2026Exome Asset Management LLC40,581$3.53M1.8%N/A0.059%
5/16/2026The Manufacturers Life Insurance Company50,769$4.42M0.0%-14.8%0.074%
5/16/2026First Light Asset Management LLC87,181$7.58M0.7%-70.5%0.127%
5/16/2026SummitTX Capital L.P.165,599$14.40M0.4%+105.1%0.242%
5/16/2026Lazard Asset Management LLC32,888$2.86M0.0%+28.6%0.048%
5/16/2026Castleark Management LLC52,279$4.55M0.2%-18.9%0.076%
5/16/2026Orbimed Advisors LLC314,100$27.32M0.5%+31.0%0.458%
5/15/2026Granahan Investment Management LLC77,709$6.76M0.3%+45.4%0.113%
5/15/2026Entropy Technologies LP10,318$897K0.0%+314.0%0.015%
5/14/2026Renaissance Technologies LLC258,011$22.44M0.0%-24.4%0.376%
5/14/2026Siren L.L.C.725,511$63.10M1.7%+45.1%1.059%
5/14/2026Inceptionr LLC4,379$381K0.1%N/A0.006%
5/14/2026Sei Investments Co.40,685$3.54M0.0%+8.7%0.059%
5/13/2026First Trust Advisors LP85,506$7.44M0.0%-3.4%0.125%
5/8/2026PNC Financial Services Group Inc.6,938$603K0.0%+48.9%0.010%
5/7/2026WCM Investment Management LLC80,620$7.01M0.0%+79.9%0.118%
5/7/2026Dimensional Fund Advisors LP19,151$1.67M0.0%-40.2%0.028%
5/7/2026AlphaCentric Advisors LLC9,297$809K0.8%+84.0%0.014%
5/7/2026Swiss National Bank112,200$9.76M0.0%+0.8%0.164%
5/5/2026Bank of New York Mellon Corp293,298$25.51M0.0%-2.6%0.428%
5/5/2026Hillsdale Investment Management Inc.40,300$3.51M0.1%-4.7%0.059%
5/4/2026Principal Financial Group Inc.5,637$490K0.0%-9.1%0.008%
5/4/2026Chicago Partners Investment Group LLC3,125$266K0.0%+14.1%0.005%
5/1/2026Fifth Third Bancorp5,260$457K0.0%N/A0.008%
5/1/2026Candriam S.C.A.464,340$40.38M0.2%+61.3%0.680%
4/30/2026Hsbc Holdings PLC14,307$1.23M0.0%N/A0.021%
4/28/2026Abel Hall LLC4,015$349K0.1%+87.6%0.006%
4/25/2026Strs Ohio28,914$2.52M0.0%+141.0%0.042%
4/22/2026Pictet Asset Management Holding SA667,046$57.33M0.1%+8.5%0.977%
4/16/2026SG Americas Securities LLC18,760$1.63M0.0%+59.8%0.027%
4/16/2026E. Ohman J or Asset Management AB4,409$383K0.0%-33.1%0.006%
3/17/2026Rockefeller Capital Management L.P.11,771$1.26M0.0%+32.7%0.017%
2/19/2026Invesco Ltd.291,150$31.17M0.0%+102.8%0.436%
2/18/2026Empowered Funds LLC4,164$446K0.0%+94.1%0.006%
2/18/2026XTX Topco Ltd10,433$1.12M0.0%N/A0.016%
2/18/2026Voloridge Investment Management LLC60,575$6.48M0.0%-83.6%0.091%
2/18/2026Virtus Investment Advisers LLC6,017$644K0.2%-14.7%0.009%
2/18/2026Wellington Management Group LLP250,156$26.78M0.0%+922.0%0.375%
2/18/2026SummitTX Capital L.P.80,729$8.64M0.3%+580.2%0.121%
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2/18/2026Orbimed Advisors LLC239,800$25.67M0.5%+11.5%0.359%
2/18/2026Opaleye Management Inc.330,000$35.32M4.6%-28.5%0.494%
2/18/2026Perceptive Advisors LLC2,546,391$272.57M4.9%-99.4%3.816%
2/18/2026Millennium Management LLC186,709$19.99M0.0%+17.7%0.280%
2/18/2026Man Group plc9,558$1.02M0.0%-92.6%0.014%
2/18/2026Janus Henderson Group PLC1,126,125$120.59M0.1%-3.0%1.687%
2/18/2026Caption Management LLC4,614$494K0.0%-83.3%0.007%
2/18/2026Cinctive Capital Management LP3,225$345K0.0%-90.8%0.005%
2/18/2026Balyasny Asset Management L.P.72,282$7.74M0.0%-79.3%0.108%
2/17/2026Guggenheim Capital LLC12,401$1.33M0.0%+442.7%0.019%


RYTM Institutional Ownership - Frequently Asked Questions

During the previous two years, 289 institutional investors and hedge funds held shares of Rhythm Pharmaceuticals. The most heavily invested institutionals were RA Capital Management L.P. ($713.62M), BlackRock Inc. ($683.60M), Vanguard Group Inc. ($664.82M), Primecap Management Co. CA ($351.84M), Baker BROS. Advisors LP ($296.87M), State Street Corp ($235.34M), and Perceptive Advisors LLC ($206.45M).Learn more on Rhythm Pharmaceuticals' institutional investors.

Of the 253 institutional investors that purchased Rhythm Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: BlackRock Inc. ($6.16M), Primecap Management Co. CA ($3.17M), Vanguard Group Inc. ($2.62M), Westfield Capital Management Co. LP ($1.83M), JPMorgan Chase & Co. ($1.46M), RA Capital Management L.P. ($1.11M), and Capital Research Global Investors ($985.09K).

Institutional investors have bought a total of 26,331,856 shares in the last 24 months. This purchase volume represents approximately $2.81B in transactions.

Of the 94 institutional investors that sold Rhythm Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Perceptive Advisors LLC ($416.73M), Primecap Management Co. CA ($1.40M), Westfield Capital Management Co. LP ($560.46K), Voloridge Investment Management LLC ($307.69K), Comerica Bank ($297.65K), Checkpoint Capital L.P. ($296.29K), and Renaissance Technologies LLC ($288.58K).

Institutional investors have sold a total of 422,734,799 shares in the last 24 months. This volume of shares sold represents approximately $45.22B in transactions.


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Institutional ownership data for NASDAQ:RYTM is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 10/9/2026. New 13F filings are added each quarter as they're published.
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