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Rhythm Pharmaceuticals (RYTM) Competitors

Rhythm Pharmaceuticals logo
$107.17 -5.36 (-4.76%)
As of 08/28/2026 04:00 PM Eastern

RYTM vs. BNTX, INSM, ROIV, INCY, and UTHR

Should you buy Rhythm Pharmaceuticals stock or one of its competitors? Rhythm Pharmaceuticals's main competitors and comparable companies include BioNTech (BNTX), Insmed (INSM), Roivant Sciences (ROIV), Incyte (INCY), and United Therapeutics (UTHR). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Rhythm Pharmaceuticals compare to BioNTech?

BioNTech (NASDAQ:BNTX) and Rhythm Pharmaceuticals (NASDAQ:RYTM) are both healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their valuation, risk, dividends, earnings, media sentiment, analyst recommendations, institutional ownership and profitability.

BioNTech has a beta of 1.27, suggesting that its stock price is 27% more volatile than the broader market. Comparatively, Rhythm Pharmaceuticals has a beta of 1.92, suggesting that its stock price is 92% more volatile than the broader market.

Rhythm Pharmaceuticals has lower revenue, but higher earnings than BioNTech. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than BioNTech, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BioNTech$3.25B7.95-$1.29B-$7.83N/A
Rhythm Pharmaceuticals$239.92M30.61-$196.54M-$3.11N/A

In the previous week, BioNTech had 5 more articles in the media than Rhythm Pharmaceuticals. MarketBeat recorded 20 mentions for BioNTech and 15 mentions for Rhythm Pharmaceuticals. Rhythm Pharmaceuticals' average media sentiment score of 1.42 beat BioNTech's score of -0.10 indicating that Rhythm Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
BioNTech
5 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
4 Negative mention(s)
4 Very Negative mention(s)
Neutral
Rhythm Pharmaceuticals
11 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

BioNTech currently has a consensus target price of $127.81, suggesting a potential upside of 25.22%. Rhythm Pharmaceuticals has a consensus target price of $141.12, suggesting a potential upside of 31.68%. Given Rhythm Pharmaceuticals' higher possible upside, analysts plainly believe Rhythm Pharmaceuticals is more favorable than BioNTech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioNTech
1 Sell rating(s)
4 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.74
Rhythm Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
15 Buy rating(s)
0 Strong Buy rating(s)
2.74

15.5% of BioNTech shares are held by institutional investors. 19.2% of BioNTech shares are held by insiders. Comparatively, 5.9% of Rhythm Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

BioNTech has a net margin of -63.54% compared to Rhythm Pharmaceuticals' net margin of -85.59%. BioNTech's return on equity of -6.86% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
BioNTech-63.54% -6.86% -6.00%
Rhythm Pharmaceuticals -85.59%-159.87%-44.00%

Summary

BioNTech beats Rhythm Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

How does Rhythm Pharmaceuticals compare to Insmed?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and Insmed (NASDAQ:INSM) are both healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their institutional ownership, analyst recommendations, media sentiment, risk, profitability, earnings, valuation and dividends.

Rhythm Pharmaceuticals has higher earnings, but lower revenue than Insmed. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Insmed, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$239.92M30.61-$196.54M-$3.11N/A
Insmed$606.42M42.69-$1.28B-$4.11N/A

Insmed has a net margin of -76.94% compared to Rhythm Pharmaceuticals' net margin of -85.59%. Insmed's return on equity of -123.94% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-85.59% -159.87% -44.00%
Insmed -76.94%-123.94%-44.30%

Rhythm Pharmaceuticals currently has a consensus price target of $141.12, indicating a potential upside of 31.68%. Insmed has a consensus price target of $205.52, indicating a potential upside of 73.38%. Given Insmed's stronger consensus rating and higher probable upside, analysts plainly believe Insmed is more favorable than Rhythm Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
15 Buy rating(s)
0 Strong Buy rating(s)
2.74
Insmed
1 Sell rating(s)
0 Hold rating(s)
22 Buy rating(s)
2 Strong Buy rating(s)
3.00

In the previous week, Rhythm Pharmaceuticals had 8 more articles in the media than Insmed. MarketBeat recorded 15 mentions for Rhythm Pharmaceuticals and 7 mentions for Insmed. Rhythm Pharmaceuticals' average media sentiment score of 1.42 beat Insmed's score of 0.90 indicating that Rhythm Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rhythm Pharmaceuticals
11 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Insmed
2 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Rhythm Pharmaceuticals has a beta of 1.92, indicating that its stock price is 92% more volatile than the broader market. Comparatively, Insmed has a beta of 0.81, indicating that its stock price is 19% less volatile than the broader market.

Summary

Insmed beats Rhythm Pharmaceuticals on 9 of the 15 factors compared between the two stocks.

How does Rhythm Pharmaceuticals compare to Roivant Sciences?

Roivant Sciences (NASDAQ:ROIV) and Rhythm Pharmaceuticals (NASDAQ:RYTM) are both healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their analyst recommendations, media sentiment, earnings, institutional ownership, valuation, profitability, risk and dividends.

Roivant Sciences presently has a consensus price target of $35.14, indicating a potential upside of 1.23%. Rhythm Pharmaceuticals has a consensus price target of $141.12, indicating a potential upside of 31.68%. Given Rhythm Pharmaceuticals' higher probable upside, analysts clearly believe Rhythm Pharmaceuticals is more favorable than Roivant Sciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Roivant Sciences
1 Sell rating(s)
1 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.85
Rhythm Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
15 Buy rating(s)
0 Strong Buy rating(s)
2.74

Rhythm Pharmaceuticals has a net margin of -85.59% compared to Roivant Sciences' net margin of -3,534.96%. Roivant Sciences' return on equity of -22.94% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Roivant Sciences-3,534.96% -22.94% -21.53%
Rhythm Pharmaceuticals -85.59%-159.87%-44.00%

Roivant Sciences has a beta of 1.12, indicating that its stock price is 12% more volatile than the broader market. Comparatively, Rhythm Pharmaceuticals has a beta of 1.92, indicating that its stock price is 92% more volatile than the broader market.

In the previous week, Roivant Sciences had 6 more articles in the media than Rhythm Pharmaceuticals. MarketBeat recorded 21 mentions for Roivant Sciences and 15 mentions for Rhythm Pharmaceuticals. Rhythm Pharmaceuticals' average media sentiment score of 1.42 beat Roivant Sciences' score of 0.74 indicating that Rhythm Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Roivant Sciences
7 Very Positive mention(s)
3 Positive mention(s)
9 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Rhythm Pharmaceuticals
11 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

64.8% of Roivant Sciences shares are owned by institutional investors. 8.8% of Roivant Sciences shares are owned by company insiders. Comparatively, 5.9% of Rhythm Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Rhythm Pharmaceuticals has higher revenue and earnings than Roivant Sciences. Roivant Sciences is trading at a lower price-to-earnings ratio than Rhythm Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Roivant Sciences$8.26M3,035.32-$299.77M-$0.53N/A
Rhythm Pharmaceuticals$239.92M30.61-$196.54M-$3.11N/A

Summary

Roivant Sciences beats Rhythm Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Rhythm Pharmaceuticals compare to Incyte?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and Incyte (NASDAQ:INCY) are both healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their institutional ownership, earnings, media sentiment, analyst recommendations, valuation, profitability, dividends and risk.

In the previous week, Incyte had 25 more articles in the media than Rhythm Pharmaceuticals. MarketBeat recorded 40 mentions for Incyte and 15 mentions for Rhythm Pharmaceuticals. Rhythm Pharmaceuticals' average media sentiment score of 1.42 beat Incyte's score of 1.34 indicating that Rhythm Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rhythm Pharmaceuticals
11 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Incyte
31 Very Positive mention(s)
3 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Positive

97.0% of Incyte shares are held by institutional investors. 5.9% of Rhythm Pharmaceuticals shares are held by company insiders. Comparatively, 16.2% of Incyte shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Rhythm Pharmaceuticals has a beta of 1.92, suggesting that its share price is 92% more volatile than the broader market. Comparatively, Incyte has a beta of 0.76, suggesting that its share price is 24% less volatile than the broader market.

Incyte has higher revenue and earnings than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Incyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$239.92M30.61-$196.54M-$3.11N/A
Incyte$5.14B4.90$1.29B$7.8515.84

Incyte has a net margin of 27.71% compared to Rhythm Pharmaceuticals' net margin of -85.59%. Incyte's return on equity of 29.93% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-85.59% -159.87% -44.00%
Incyte 27.71%29.93%22.88%

Rhythm Pharmaceuticals currently has a consensus target price of $141.12, indicating a potential upside of 31.68%. Incyte has a consensus target price of $123.10, indicating a potential downside of 1.02%. Given Rhythm Pharmaceuticals' stronger consensus rating and higher probable upside, research analysts plainly believe Rhythm Pharmaceuticals is more favorable than Incyte.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
15 Buy rating(s)
0 Strong Buy rating(s)
2.74
Incyte
0 Sell rating(s)
12 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.56

Summary

Incyte beats Rhythm Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

How does Rhythm Pharmaceuticals compare to United Therapeutics?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and United Therapeutics (NASDAQ:UTHR) are both healthcare companies, but which is the superior investment? We will contrast the two companies based on the strength of their risk, earnings, media sentiment, analyst recommendations, dividends, valuation, profitability and institutional ownership.

United Therapeutics has higher revenue and earnings than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than United Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$239.92M30.61-$196.54M-$3.11N/A
United Therapeutics$3.18B6.95$1.33B$27.9518.44

94.1% of United Therapeutics shares are held by institutional investors. 5.9% of Rhythm Pharmaceuticals shares are held by company insiders. Comparatively, 8.6% of United Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Rhythm Pharmaceuticals has a beta of 1.92, indicating that its share price is 92% more volatile than the broader market. Comparatively, United Therapeutics has a beta of 0.59, indicating that its share price is 41% less volatile than the broader market.

United Therapeutics has a net margin of 41.56% compared to Rhythm Pharmaceuticals' net margin of -85.59%. United Therapeutics' return on equity of 20.18% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-85.59% -159.87% -44.00%
United Therapeutics 41.56%20.18%17.98%

In the previous week, United Therapeutics had 28 more articles in the media than Rhythm Pharmaceuticals. MarketBeat recorded 43 mentions for United Therapeutics and 15 mentions for Rhythm Pharmaceuticals. United Therapeutics' average media sentiment score of 1.47 beat Rhythm Pharmaceuticals' score of 1.42 indicating that United Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rhythm Pharmaceuticals
11 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
United Therapeutics
34 Very Positive mention(s)
5 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Rhythm Pharmaceuticals currently has a consensus price target of $141.12, suggesting a potential upside of 31.68%. United Therapeutics has a consensus price target of $646.00, suggesting a potential upside of 25.32%. Given Rhythm Pharmaceuticals' higher probable upside, research analysts plainly believe Rhythm Pharmaceuticals is more favorable than United Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
15 Buy rating(s)
0 Strong Buy rating(s)
2.74
United Therapeutics
0 Sell rating(s)
2 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.85

Summary

United Therapeutics beats Rhythm Pharmaceuticals on 12 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding RYTM and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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RYTM vs. The Competition

MetricRhythm PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$7.34B$3.94B$7.21B$12.91B
Dividend YieldN/A3.61%2.54%11.28%
P/E Ratio-34.4611.62273.1625.45
Price / Sales30.611,315.05614.8186.98
Price / CashN/A106.3976.7453.00
Price / Book71.4516.5312.986.14
Net Income-$196.54M-$22.80M$3.48B$348.86M
7 Day Performance-2.57%-0.31%0.13%-0.80%
1 Month Performance1.35%9.80%7.08%4.13%
1 Year Performance3.90%55.66%24.67%15.17%

Rhythm Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
RYTM
Rhythm Pharmaceuticals
2.874 of 5 stars
$107.17
-4.8%
$141.12
+31.7%
+3.9%$7.34B$239.92MN/A140
BNTX
BioNTech
3.29 of 5 stars
$112.82
-3.2%
$127.81
+13.3%
+2.1%$29.48B$3.25BN/A7,807
INSM
Insmed
3.3825 of 5 stars
$123.98
-1.4%
$205.52
+65.8%
-12.9%$27.47B$1.14BN/A1,664
ROIV
Roivant Sciences
2.0218 of 5 stars
$36.36
+0.2%
$35.14
-3.4%
+190.9%$26.22B$7.53MN/A860
INCY
Incyte
3.6811 of 5 stars
$127.98
+0.1%
$123.10
-3.8%
+47.0%$25.91B$5.14B16.302,844

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This page (NASDAQ:RYTM) was last updated on 8/30/2026 by MarketBeat.com Staff.
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