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Rhythm Pharmaceuticals (RYTM) Competitors

Rhythm Pharmaceuticals logo
$97.71 -1.31 (-1.32%)
Closing price 09/18/2026 04:00 PM Eastern
Extended Trading
$97.74 +0.03 (+0.03%)
As of 09/18/2026 07:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

RYTM vs. INSM, BNTX, INCY, ROIV, and GMAB

Should you buy Rhythm Pharmaceuticals stock or one of its competitors? Rhythm Pharmaceuticals's main competitors and comparable companies include Insmed (INSM), BioNTech (BNTX), Incyte (INCY), Roivant Sciences (ROIV), and Genmab A/S (GMAB). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Rhythm Pharmaceuticals compare to Insmed?

Insmed (NASDAQ:INSM) and Rhythm Pharmaceuticals (NASDAQ:RYTM) are both healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their earnings, institutional ownership, dividends, risk, valuation, profitability, analyst recommendations and media sentiment.

In the previous week, Rhythm Pharmaceuticals had 11 more articles in the media than Insmed. MarketBeat recorded 17 mentions for Rhythm Pharmaceuticals and 6 mentions for Insmed. Insmed's average media sentiment score of 0.84 beat Rhythm Pharmaceuticals' score of 0.38 indicating that Insmed is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Insmed
3 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Rhythm Pharmaceuticals
3 Very Positive mention(s)
3 Positive mention(s)
8 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Rhythm Pharmaceuticals has lower revenue, but higher earnings than Insmed. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Insmed, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Insmed$606.42M43.21-$1.28B-$4.11N/A
Rhythm Pharmaceuticals$189.76M35.29-$196.54M-$3.11N/A

Insmed presently has a consensus target price of $204.91, indicating a potential upside of 70.76%. Rhythm Pharmaceuticals has a consensus target price of $140.67, indicating a potential upside of 43.96%. Given Insmed's stronger consensus rating and higher possible upside, equities research analysts clearly believe Insmed is more favorable than Rhythm Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Insmed
1 Sell rating(s)
0 Hold rating(s)
22 Buy rating(s)
2 Strong Buy rating(s)
3.00
Rhythm Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
17 Buy rating(s)
0 Strong Buy rating(s)
2.76

Insmed has a net margin of -76.94% compared to Rhythm Pharmaceuticals' net margin of -85.59%. Insmed's return on equity of -123.94% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Insmed-76.94% -123.94% -44.30%
Rhythm Pharmaceuticals -85.59%-159.87%-44.00%

Insmed has a beta of 0.82, meaning that its share price is 18% less volatile than the broader market. Comparatively, Rhythm Pharmaceuticals has a beta of 1.97, meaning that its share price is 97% more volatile than the broader market.

Summary

Insmed beats Rhythm Pharmaceuticals on 10 of the 15 factors compared between the two stocks.

How does Rhythm Pharmaceuticals compare to BioNTech?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and BioNTech (NASDAQ:BNTX) are both healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their institutional ownership, earnings, media sentiment, valuation, dividends, profitability, risk and analyst recommendations.

In the previous week, BioNTech had 12 more articles in the media than Rhythm Pharmaceuticals. MarketBeat recorded 29 mentions for BioNTech and 17 mentions for Rhythm Pharmaceuticals. Rhythm Pharmaceuticals' average media sentiment score of 0.38 beat BioNTech's score of 0.14 indicating that Rhythm Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rhythm Pharmaceuticals
3 Very Positive mention(s)
3 Positive mention(s)
8 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
BioNTech
12 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Neutral

Rhythm Pharmaceuticals has a beta of 1.97, indicating that its share price is 97% more volatile than the broader market. Comparatively, BioNTech has a beta of 1.29, indicating that its share price is 29% more volatile than the broader market.

Rhythm Pharmaceuticals currently has a consensus target price of $140.67, suggesting a potential upside of 43.96%. BioNTech has a consensus target price of $126.00, suggesting a potential upside of 31.17%. Given Rhythm Pharmaceuticals' stronger consensus rating and higher probable upside, equities research analysts plainly believe Rhythm Pharmaceuticals is more favorable than BioNTech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
17 Buy rating(s)
0 Strong Buy rating(s)
2.76
BioNTech
1 Sell rating(s)
5 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.68

Rhythm Pharmaceuticals has higher earnings, but lower revenue than BioNTech. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than BioNTech, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$189.76M35.29-$196.54M-$3.11N/A
BioNTech$3.25B7.48-$1.29B-$7.83N/A

BioNTech has a net margin of -63.54% compared to Rhythm Pharmaceuticals' net margin of -85.59%. BioNTech's return on equity of -6.86% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-85.59% -159.87% -44.00%
BioNTech -63.54%-6.86%-6.00%

15.5% of BioNTech shares are held by institutional investors. 5.9% of Rhythm Pharmaceuticals shares are held by company insiders. Comparatively, 19.2% of BioNTech shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Summary

BioNTech beats Rhythm Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Rhythm Pharmaceuticals compare to Incyte?

Incyte (NASDAQ:INCY) and Rhythm Pharmaceuticals (NASDAQ:RYTM) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their earnings, dividends, profitability, analyst recommendations, institutional ownership, media sentiment, risk and valuation.

Incyte presently has a consensus target price of $124.05, indicating a potential downside of 1.01%. Rhythm Pharmaceuticals has a consensus target price of $140.67, indicating a potential upside of 43.96%. Given Rhythm Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Rhythm Pharmaceuticals is more favorable than Incyte.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Incyte
0 Sell rating(s)
13 Hold rating(s)
11 Buy rating(s)
1 Strong Buy rating(s)
2.52
Rhythm Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
17 Buy rating(s)
0 Strong Buy rating(s)
2.76

Incyte has a net margin of 27.71% compared to Rhythm Pharmaceuticals' net margin of -85.59%. Incyte's return on equity of 29.93% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Incyte27.71% 29.93% 22.88%
Rhythm Pharmaceuticals -85.59%-159.87%-44.00%

97.0% of Incyte shares are held by institutional investors. 16.2% of Incyte shares are held by company insiders. Comparatively, 5.9% of Rhythm Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Incyte has higher revenue and earnings than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Incyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Incyte$5.14B4.94$1.29B$7.8515.96
Rhythm Pharmaceuticals$189.76M35.29-$196.54M-$3.11N/A

Incyte has a beta of 0.77, indicating that its stock price is 23% less volatile than the broader market. Comparatively, Rhythm Pharmaceuticals has a beta of 1.97, indicating that its stock price is 97% more volatile than the broader market.

In the previous week, Rhythm Pharmaceuticals had 8 more articles in the media than Incyte. MarketBeat recorded 17 mentions for Rhythm Pharmaceuticals and 9 mentions for Incyte. Incyte's average media sentiment score of 0.75 beat Rhythm Pharmaceuticals' score of 0.38 indicating that Incyte is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Incyte
3 Very Positive mention(s)
3 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Rhythm Pharmaceuticals
3 Very Positive mention(s)
3 Positive mention(s)
8 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Incyte beats Rhythm Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

How does Rhythm Pharmaceuticals compare to Roivant Sciences?

Roivant Sciences (NASDAQ:ROIV) and Rhythm Pharmaceuticals (NASDAQ:RYTM) are both healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their dividends, valuation, analyst recommendations, media sentiment, profitability, institutional ownership, earnings and risk.

Roivant Sciences presently has a consensus target price of $45.64, indicating a potential upside of 14.75%. Rhythm Pharmaceuticals has a consensus target price of $140.67, indicating a potential upside of 43.96%. Given Rhythm Pharmaceuticals' higher probable upside, analysts plainly believe Rhythm Pharmaceuticals is more favorable than Roivant Sciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Roivant Sciences
1 Sell rating(s)
1 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.85
Rhythm Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
17 Buy rating(s)
0 Strong Buy rating(s)
2.76

In the previous week, Rhythm Pharmaceuticals had 8 more articles in the media than Roivant Sciences. MarketBeat recorded 17 mentions for Rhythm Pharmaceuticals and 9 mentions for Roivant Sciences. Roivant Sciences' average media sentiment score of 0.85 beat Rhythm Pharmaceuticals' score of 0.38 indicating that Roivant Sciences is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Roivant Sciences
5 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Rhythm Pharmaceuticals
3 Very Positive mention(s)
3 Positive mention(s)
8 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Rhythm Pharmaceuticals has a net margin of -85.59% compared to Roivant Sciences' net margin of -3,534.96%. Roivant Sciences' return on equity of -22.94% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Roivant Sciences-3,534.96% -22.94% -21.53%
Rhythm Pharmaceuticals -85.59%-159.87%-44.00%

64.8% of Roivant Sciences shares are owned by institutional investors. 8.8% of Roivant Sciences shares are owned by insiders. Comparatively, 5.9% of Rhythm Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Roivant Sciences has a beta of 1.12, meaning that its share price is 12% more volatile than the broader market. Comparatively, Rhythm Pharmaceuticals has a beta of 1.97, meaning that its share price is 97% more volatile than the broader market.

Rhythm Pharmaceuticals has higher revenue and earnings than Roivant Sciences. Roivant Sciences is trading at a lower price-to-earnings ratio than Rhythm Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Roivant Sciences$8.26M3,477.80-$299.77M-$0.53N/A
Rhythm Pharmaceuticals$189.76M35.29-$196.54M-$3.11N/A

Summary

Roivant Sciences beats Rhythm Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Rhythm Pharmaceuticals compare to Genmab A/S?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and Genmab A/S (NASDAQ:GMAB) are both healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their dividends, risk, profitability, institutional ownership, media sentiment, valuation, earnings and analyst recommendations.

Rhythm Pharmaceuticals presently has a consensus price target of $140.67, indicating a potential upside of 43.96%. Genmab A/S has a consensus price target of $39.50, indicating a potential upside of 13.70%. Given Rhythm Pharmaceuticals' higher possible upside, equities research analysts plainly believe Rhythm Pharmaceuticals is more favorable than Genmab A/S.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
17 Buy rating(s)
0 Strong Buy rating(s)
2.76
Genmab A/S
0 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.85

Genmab A/S has higher revenue and earnings than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Genmab A/S, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$189.76M35.29-$196.54M-$3.11N/A
Genmab A/S$3.72B5.83$963M$1.2727.35

In the previous week, Rhythm Pharmaceuticals had 5 more articles in the media than Genmab A/S. MarketBeat recorded 17 mentions for Rhythm Pharmaceuticals and 12 mentions for Genmab A/S. Genmab A/S's average media sentiment score of 0.64 beat Rhythm Pharmaceuticals' score of 0.38 indicating that Genmab A/S is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rhythm Pharmaceuticals
3 Very Positive mention(s)
3 Positive mention(s)
8 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Genmab A/S
2 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Genmab A/S has a net margin of 19.08% compared to Rhythm Pharmaceuticals' net margin of -85.59%. Genmab A/S's return on equity of 14.89% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-85.59% -159.87% -44.00%
Genmab A/S 19.08%14.89%7.73%

Rhythm Pharmaceuticals has a beta of 1.97, meaning that its share price is 97% more volatile than the broader market. Comparatively, Genmab A/S has a beta of 0.84, meaning that its share price is 16% less volatile than the broader market.

7.1% of Genmab A/S shares are owned by institutional investors. 5.9% of Rhythm Pharmaceuticals shares are owned by company insiders. Comparatively, 1.5% of Genmab A/S shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Summary

Genmab A/S beats Rhythm Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding RYTM and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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RYTM vs. The Competition

MetricRhythm PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$6.79B$3.91B$7.25B$13.13B
Dividend YieldN/A3.65%2.57%12.94%
P/E Ratio-31.4214.08273.8125.39
Price / Sales35.291,407.75692.78109.00
Price / CashN/A110.7577.4251.66
Price / Book46.9815.4510.456.33
Net Income-$196.54M-$22.78M$3.48B$358.24M
7 Day Performance-6.69%-1.22%0.88%1.17%
1 Month Performance-15.57%-4.44%-1.59%-2.59%
1 Year Performance1.72%37.78%18.08%5.97%

Rhythm Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
RYTM
Rhythm Pharmaceuticals
2.7797 of 5 stars
$97.71
-1.3%
$140.67
+44.0%
-0.8%$6.79B$189.76MN/A414
INSM
Insmed
3.0533 of 5 stars
$126.29
flat
$205.52
+62.7%
-17.7%$27.58B$606.42MN/A1,664
BNTX
BioNTech
4.3424 of 5 stars
$103.76
flat
$126.00
+21.4%
-0.3%$26.24B$3.25BN/A7,807
INCY
Incyte
3.3476 of 5 stars
$126.75
flat
$124.05
-2.1%
+45.7%$25.69B$5.14B16.152,844
ROIV
Roivant Sciences
2.8404 of 5 stars
$34.93
flat
$35.14
+0.6%
+163.6%$25.23B$8.26MN/A860

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This page (NASDAQ:RYTM) was last updated on 9/19/2026 by MarketBeat.com Staff.
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