Spruce Street Capital Lp Top Holdings and 13F Report (2026) About Spruce Street Capital LpInvestment ActivitySpruce Street Capital Lp has $509.68 million in total holdings as of June 30, 2026.Spruce Street Capital Lp owns shares of 30 different stocks, but just 14 companies or ETFs make up 80% of its holdings.Approximately 12.29% of the portfolio was purchased this quarter.About 8.89% of the portfolio was sold this quarter.This quarter, Spruce Street Capital Lp has purchased 28 new stocks and bought additional shares in 8 stocks.Spruce Street Capital Lp sold shares of 1 stock and completely divested from 3 stocks this quarter.Largest Holdings KINIKSA PHARMACEUTICALS INTL $58,710,577Relay Therapeutics $55,832,979LB PHARMACEUTICALS INC $44,663,240Relmada Therapeutics $44,227,990ALTO NEUROSCIENCE INC $35,706,910 Largest New Holdings this Quarter N44821101 - InflaRx $11,988,924 HoldingG75226103 - RESEARCH ALLIANCE CORP III $5,350,000 Holding98887Q104 - Zai Lab $5,303,090 Holding004468500 - Achieve Life Sciences $4,810,240 HoldingG50765109 - JATT II ACQUISITION CORP $1,817,600 Holding Largest Purchases this Quarter InflaRx 5,352,198 shares (about $11.99M)Alkermes 225,884 shares (about $11.84M)KINIKSA PHARMACEUTICALS INTL 157,007 shares (about $10.04M)RESEARCH ALLIANCE CORP III 500,000 shares (about $5.35M)Zai Lab 279,110 shares (about $5.30M) Largest Sales this Quarter DIANTHUS THERAPEUTICS INC 18,458 shares (about $1.80M) Sector Allocation Over TimeMap of 500 Largest Holdings ofSpruce Street Capital Lp Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorKINIKSA PHARMACEUTICALS INTL$58,710,577$10,040,598 â–²20.6%918,07011.5%ORD SHS CL ARLAYRelay Therapeutics$55,832,9790.0%2,984,12511.0%HealthcareLB PHARMACEUTICALS INC$44,663,2400.0%1,376,1598.8%COM SHSRLMDRelmada Therapeutics$44,227,990$894,161 â–²2.1%6,391,3288.7%HealthcareALTO NEUROSCIENCE INC$35,706,910$734,618 â–²2.1%1,353,0477.0%COM SHSDIANTHUS THERAPEUTICS INC$34,587,464$1,799,286 â–¼-4.9%354,8166.8%COMALKSAlkermes$28,496,383$11,835,192 â–²71.0%543,8765.6%HealthcareSVRASavara$21,267,868$427,510 â–²2.1%3,452,5764.2%HealthcarePCVXVaxcyte$17,790,512$3,507,448 â–²24.6%306,0473.5%HealthcareELVNEnliven Therapeutics$16,697,0550.0%329,0063.3%HealthcareENTAEnanta Pharmaceuticals$15,873,698$2,276,419 â–²16.7%1,088,7313.1%HealthcarePERSPECTIVE THERAPEUTICS INC$12,596,305$3,637,870 â–²40.6%3,693,9312.5%COM NEWIFRXInflaRx$11,988,924$11,988,924 â–²New Holding5,352,1982.4%HealthcareSURROZEN INC$11,211,4380.0%432,0402.2%COM NEWALUMIS INC$11,047,0320.0%392,5742.2%COMIPSCCentury Therapeutics$9,944,6820.0%4,059,0542.0%HealthcareNERVMinerva Neurosciences$9,188,0250.0%1,655,5001.8%HealthcareSAB BIOTHERAPEUTICS INC$8,574,1580.0%2,198,5021.7%COM NEWAN2 THERAPEUTICS INC$8,039,5930.0%1,661,0731.6%COMERASErasca$7,740,9880.0%422,5431.5%HealthcareINHIBIKASE THERAPEUTICS INC$7,270,6540.0%3,581,6031.4%COM NEWRESEARCH ALLIANCE CORP III$5,350,000$5,350,000 â–²New Holding500,0001.0%ORD SHS CL AHELIX ACQUISITION CORP III$5,320,0000.0%500,0001.0%USD CL A ORD SHSZLABZai Lab$5,303,090$5,303,090 â–²New Holding279,1101.0%HealthcareACHVAchieve Life Sciences$4,810,240$4,810,240 â–²New Holding736,6370.9%HealthcareLEXEO THERAPEUTICS INC$4,322,6000.0%928,5930.8%COMALECAlector$4,223,1470.0%2,101,0680.8%HealthcareLEONABIO INC$3,618,1120.0%393,7010.7%COMCRVSCorvus Pharmaceuticals$3,459,8800.0%231,5850.7%HealthcareJATT II ACQUISITION CORP$1,817,600$1,817,600 â–²New Holding160,0000.4%ORD SHSCNTACentessa Pharmaceuticals$0$19,456,802 â–¼-100.0%00.0%HealthcareKALVKalVista Pharmaceuticals$0$18,070,319 â–¼-100.0%00.0%HealthcareMAZE THERAPEUTICS INC$0$5,970,000 â–¼-100.0%00.0%COMShowing largest 100 holdings. 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