Tcg Crossover Management, LLC Top Holdings and 13F Report (2026)

About Tcg Crossover Management, LLC

Investment Activity

Tcg Crossover Management, LLC has $4.16 billion in total holdings as of June 30, 2026.
Tcg Crossover Management, LLC owns shares of 54 different stocks, but just 21 companies or ETFs make up 80% of its holdings.
Approximately 11.42% of the portfolio was purchased this quarter.
About 11.84% of the portfolio was sold this quarter.
This quarter, Tcg Crossover Management, LLC has purchased 49 new stocks and bought additional shares in 2 stocks.
Tcg Crossover Management, LLC sold shares of 9 stocks and completely divested from 7 stocks this quarter.

Largest Holdings

ABIVAX SA AMERICAN DEPOSITARY SHARES: $800,603,959
Tango Therapeutics: $283,878,343
CG ONCOLOGY INC: $260,768,136
Cogent Biosciences: $187,866,673
Immunovant: $171,766,278

Largest New Holdings this Quarter

98887Q104 - Zai Lab: $116,614,913 Holding
05153U107 - Aura Biosciences: $67,686,664 Holding
337185102 - FIRST TRACKS BIOTHERAPEUTICS: $58,253,516 Holding
28106W103 - Editas Medicine: $36,000,000 Holding
N69605108 - Pharvaris: $34,864,559 Holding

Largest Purchases this Quarter

Zai Lab: 6,137,627 shares (about $116.61M)
Aura Biosciences: 9,533,333 shares (about $67.69M)
FIRST TRACKS BIOTHERAPEUTICS: 2,895,304 shares (about $58.25M)
AVALO THERAPEUTICS INC: 2,278,737 shares (about $42.11M)
Editas Medicine: 11,111,111 shares (about $36M)

Largest Sales this Quarter

ABIVAX SA AMERICAN DEPOSITARY SHARES: 473,251 shares (about $63.07M)
Tango Therapeutics: 1,449,870 shares (about $45.32M)
Revolution Medicines: 235,574 shares (about $44.12M)
Biohaven: 2,851,365 shares (about $42.43M)
ALX Oncology: 7,356,362 shares (about $15.23M)

Sector Allocation Over Time

Selling

Neutral

Buying

Latest 13F Holdings and Changes Since Previous Quarterly Filing

Issuer Name	Holdings Value	Approximate Purchase/Sale	Change in Shares	Shares Held	% of Portfolio	Sector
ABIVAX SA AMERICAN DEPOSITARY SHARES	$800,603,959	$63,065,428 â–¼	-7.3%	6,007,834	19.2%	COMM
TNGX Tango Therapeutics	$283,878,343	$45,322,936 â–¼	-13.8%	9,081,201	6.8%	Healthcare
CG ONCOLOGY INC	$260,768,136		0.0%	3,670,206	6.3%	COMM
COGT Cogent Biosciences	$187,866,673	$3,578,125 â–¼	-1.9%	4,854,436	4.5%	Healthcare
IMVT Immunovant	$171,766,278		0.0%	4,457,988	4.1%	Healthcare
SPYRE THERAPEUTICS INC	$168,733,670		0.0%	1,900,582	4.1%	COMM
DIANTHUS THERAPEUTICS INC	$163,437,308		0.0%	1,676,624	3.9%	COMM
MIRM Mirum Pharmaceuticals	$124,334,076		0.0%	1,062,049	3.0%	Healthcare
ZLAB Zai Lab	$116,614,913	$116,614,913 â–²	New Holding	6,137,627	2.8%	Healthcare
AMLX Amylyx Pharmaceuticals	$112,138,864		0.0%	6,243,812	2.7%	Healthcare
GLUE Monte Rosa Therapeutics	$111,856,054		0.0%	4,622,151	2.7%	Healthcare
BCRX BioCryst Pharmaceuticals	$110,209,680		0.0%	11,020,968	2.6%	Healthcare
VOR BIOPHARMA INC	$104,441,366		0.0%	5,673,078	2.5%	COMM
TYRA Tyra Biosciences	$103,772,421		0.0%	3,248,980	2.5%	Healthcare
DYNE THERAPEUTICS INC	$102,502,348		0.0%	4,615,144	2.5%	COMM
IRON Disc Medicine	$98,143,787		0.0%	1,341,862	2.4%	Healthcare
RLAY Relay Therapeutics	$79,954,491		0.0%	4,273,356	1.9%	Healthcare
SVRA Savara	$76,151,183		0.0%	12,362,205	1.8%	Healthcare
AURA Aura Biosciences	$67,686,664	$67,686,664 â–²	New Holding	9,533,333	1.6%	Healthcare
RVMD Revolution Medicines	$63,843,565	$44,118,299 â–¼	-40.9%	340,899	1.5%	Healthcare
FIRST TRACKS BIOTHERAPEUTICS	$58,253,516	$58,253,516 â–²	New Holding	2,895,304	1.4%	COMM
KOD Kodiak Sciences	$56,318,161		0.0%	1,445,538	1.4%	Healthcare
AVALO THERAPEUTICS INC	$55,756,378	$42,111,060 â–²	308.6%	3,017,120	1.3%	COMM
LB PHARMACEUTICALS INC	$46,972,446	$12,728,169 â–¼	-21.3%	1,447,310	1.1%	COMM
IPSC Century Therapeutics	$43,401,690		0.0%	17,754,430	1.0%	Healthcare
TECTONIC THERAPEUTIC INC	$41,418,128		0.0%	1,204,891	1.0%	COMM
XNCR Xencor	$39,479,422		0.0%	2,452,138	0.9%	Healthcare
SURROZEN INC	$38,226,971		0.0%	1,473,101	0.9%	COMM
EDIT Editas Medicine	$36,000,000	$36,000,000 â–²	New Holding	11,111,111	0.9%	Healthcare
MBX BIOSCIENCES INC	$35,880,000		0.0%	650,000	0.9%	COMM
PHVS Pharvaris	$34,864,559	$34,864,559 â–²	New Holding	1,008,229	0.8%	Healthcare
SLN Silence Therapeutics	$33,308,489		0.0%	3,033,560	0.8%	Healthcare
IFRX InflaRx	$32,480,000	$32,480,000 â–²	New Holding	14,500,000	0.8%	Healthcare
ALT Altimmune	$30,400,000	$30,400,000 â–²	New Holding	10,000,000	0.7%	Healthcare
JANX Janux Therapeutics	$27,488,517		0.0%	1,789,617	0.7%	Healthcare
PERSPECTIVE THERAPEUTICS INC	$26,992,083		0.0%	7,915,567	0.6%	COMM
AGOMAB THERAPEUTICS NV	$26,650,964		0.0%	2,053,233	0.6%	ADRS
BHVN Biohaven	$26,485,686	$42,428,312 â–¼	-61.6%	1,779,952	0.6%	Healthcare
AKTIS ONCOLOGY INC	$22,450,129	$22,450,129 â–²	New Holding	696,560	0.5%	COMM
ALEC Alector	$20,100,000		0.0%	10,000,000	0.5%	Healthcare
FORTE BIOSCIENCES INC	$19,550,000	$19,550,000 â–²	New Holding	920,000	0.5%	COMM
MONOPAR THERAPEUTICS INC	$18,826,047	$6,594,630 â–²	53.9%	203,327	0.5%	COMM
OCUL Ocular Therapeutix	$16,180,925		0.0%	1,647,752	0.4%	Healthcare
ADCT ADC Therapeutics	$12,187,487		0.0%	11,390,175	0.3%	Healthcare
ALXO ALX Oncology	$11,706,858	$15,227,669 â–¼	-56.5%	5,655,487	0.3%	Healthcare
TRDA Entrada Therapeutics	$7,803,293	$9,032,707 â–¼	-53.7%	1,060,230	0.2%	Healthcare
CGEM Cullinan Therapeutics	$7,407,573		0.0%	406,786	0.2%	Healthcare
ARVN Arvinas	$5,875,984	$13,963,816 â–¼	-70.4%	707,098	0.1%	Healthcare
KORRO BIO INC	$5,486,847		0.0%	416,301	0.1%	COMM
RESEARCH ALLIANCE CORP CL A	$5,350,000	$5,350,000 â–²	New Holding	500,000	0.1%	COMM
LEONABIO INC	$4,267,818		0.0%	464,398	0.1%	COMM
JATT II ACQUISITION CORP	$2,272,000	$2,272,000 â–²	New Holding	200,000	0.1%	COMM
CNTX Context Therapeutics	$1,485,945		0.0%	2,682,696	0.0%	Healthcare
EIKON THERAPEUTICS INC	$494,621	$494,621 â–²	New Holding	37,902	0.0%	COMM
CNTA Centessa Pharmaceuticals	$0	$170,258,986 â–¼	-100.0%	0	0.0%	Healthcare
FULC Fulcrum Therapeutics	$0	$40,267,500 â–¼	-100.0%	0	0.0%	Healthcare
LQDA Liquidia	$0	$15,211,032 â–¼	-100.0%	0	0.0%	Healthcare
URGN Urogen Pharma	$0	$7,288,463 â–¼	-100.0%	0	0.0%	Healthcare
GPCR Structure Therapeutics	$0	$6,767,810 â–¼	-100.0%	0	0.0%	Healthcare
UPSTREAM BIO INC	$0	$1,629,567 â–¼	-100.0%	0	0.0%	COMM
VTGN VistaGen Therapeutics	$0	$1,529,665 â–¼	-100.0%	0	0.0%	Healthcare

Showing largest 100 holdings. View all holdings.

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Tcg Crossover Management, LLC Top Holdings and 13F Report (2026)

About Tcg Crossover Management, LLC

Investment Activity

Largest Holdings

Largest New Holdings this Quarter

Largest Purchases this Quarter

Largest Sales this Quarter

Sector Allocation Over Time

Latest 13F Holdings and Changes Since Previous Quarterly Filing

More Institutional Buying and Selling Information

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Tcg Crossover Management, LLC Top Holdings and 13F Report (2026)

About Tcg Crossover Management, LLC

Investment Activity

Largest Holdings

Largest New Holdings this Quarter

Largest Purchases this Quarter

Largest Sales this Quarter

Sector Allocation Over Time

Map of 500 Largest Holdings ofTcg Crossover Management, LLC

Latest 13F Holdings and Changes Since Previous Quarterly Filing

More Institutional Buying and Selling Information

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools