NASDAQ:ME 23andMe Q2 2025 Earnings Report $0.50 -0.27 (-35.32%) Closing price 03/28/2025Extended Trading$0.50 0.00 (0.00%) As of 03/28/2025 08:00 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Earnings HistoryForecast 23andMe EPS ResultsActual EPS-$2.32Consensus EPS N/ABeat/MissN/AOne Year Ago EPSN/A23andMe Revenue ResultsActual Revenue$44.07 millionExpected Revenue$50.30 millionBeat/MissMissed by -$6.23 millionYoY Revenue GrowthN/A23andMe Announcement DetailsQuarterQ2 2025Date11/12/2024TimeN/AConference Call DateTuesday, November 12, 2024Conference Call Time8:00AM ETConference Call ResourcesConference Call AudioConference Call TranscriptPress Release (8-K)Quarterly Report (10-Q)Earnings HistoryCompany ProfilePowered by 23andMe Q2 2025 Earnings Call TranscriptProvided by QuartrNovember 12, 2024 ShareLink copied to clipboard.There are 4 speakers on the call. Operator00:00:00Good day and thank you for standing by. Welcome to the 23 andMe Fiscal Year 2025 Second Quarter Earnings Call. At this time, all participants are in a listen only mode. Please be advised that this call is being recorded. I would now like to turn the conference over to your speaker for today, Katie Watson, Vice President of Communications. Operator00:00:21Please go ahead. Speaker 100:00:27Thank you. Before we begin, I encourage everyone to go to investors. 23me.com to find the press release we issued earlier today reporting our financial results for the Q2 of fiscal 2025. A replay of today's webcast will also be available on our website. Please note that certain statements made during this call regarding matters that are not historical facts, including but not limited to management's outlook or predictions for future periods are forward looking statements. Speaker 100:00:58These statements are based solely on information that is now available to us. We encourage you to review the section entitled Forward Looking Statements in our press release, which applies to this call. Also, please refer to our SEC filings, which can be found on our website and the SEC's website for a discussion of numerous factors that may impact our future performance. We also discuss certain non GAAP measures. Important information on our use of these measures and reconciliations to U. Speaker 100:01:27S. GAAP may be found in our earnings release. Joining us on our call today are Ann Wojcicki, our Chief Executive Officer and Co Founder and Jo Selzavage, our Chief Financial and Accounting Officer. I'd now like to turn the call over to Anne. Speaker 200:01:43Thanks, Katie. Hello, everyone. I'd like to start today's call by addressing recent developments at the company and then we'll get into the Q2. In late October, 23andme reconstituted our Board of Directors with the appointment of 3 new independent directors. We are pleased that these accomplished and experienced executives who are committed to our mission could jump in immediately. Speaker 200:02:07We have fulfilled our obligations as a public company and regain compliance with the NASDAQ listing standards by reconstituting our Board and executing a reverse stock split. In addition, yesterday, we announced that 23. Me is undertaking a business restructuring to streamline operations, reduce costs and position the company for long term success. Under this restructuring, we are discontinuing further development of all therapeutic programs and reducing our workforce by approximately 40%. Joe will discuss the financial impact of the restructuring in his prepared remarks. Speaker 200:02:45We continue to believe in the promise shown by our clinical stage oncology assets and our preclinical immunology pipeline. As we immediately start the wind down process for the therapeutics division, we will be actively exploring a range of strategic alternatives for our therapeutics pipeline that will enable their continued development outside of 23andme. We intend to continue supporting the collection of data and monitoring of patients in our clinical trials, while the strategic alternative process and wind down are completed. These are difficult but necessary actions that we believe begin putting 23andme on a more sustainable path and positioning the company for the future. We appreciate the dedication and contributions of our team to our mission and are committed to supporting the impact of employees through this transition. Speaker 200:03:37We also remain deeply grateful to the patients, investigators and study staff for their participation in our clinical trials and will work to ensure development efforts can continue for the benefit of patients. Now I'll turn to the Q2 of our fiscal year 2025. We made considerable strides in our key objective of becoming a sustainable cash flow positive company, while remaining committed to our goal of helping millions of people live longer healthier lives. The team continues to leverage the full spectrum of 23 andMe platform to deliver integrated preventive health services and genetic insights. We made our Speaker 300:04:17total health membership service a comprehensive longevity Speaker 200:04:17platform combining advanced exome sequencing, a comprehensive longevity platform combining advanced exome sequencing, lab tests and guidance from clinicians specifically trained in genetics available to our entire customer base. We believe the future of preventive health is understanding your complete health picture, including genetics, lab testing, family health history and other data to help derive a truly personalized health plan. 23andme made significant progress in Q2, bringing the power of our research, genetic insight and telehealth platform to serve critical consumer needs. As part of our focus on prevention and longevity, we launched a number of weight management initiatives in Q2. Studies estimate that BMI is 40% to 70% influenced by genetics and that elevated BMI is associated with up to 9 fewer years lived in good health. Speaker 200:05:14A few highlights. We launched and enrolled thousands of participants in a new study to understand how genetics can impact GLP-one efficacy, side effects and length of treatment. We launched a new genetic report on emotional eating utilizing 23andme's polygenic riskScore technology for 23andme plus premium subscribers. Emotional eating impacts up to 60% of people with a high BMI and knowing this can inform weight management approaches. We also launched a GLP-one weight loss telehealth membership on the Lemonade Health platform that enables members to be prescribed and receive brand name or compounded semaglutide medications. Speaker 200:06:01These medications can be life changing and an important tool for prevention and longevity and offering our customers access to them in a convenient cost effective manner is consistent with our mission. We continue to improve and add to 23. Me's market leading ancestry composition and historical matches features with new regions for Germanic Europe, Scandinavia and Japan and new historical matches, our subscription only feature, with historical figures from the medieval Swahili Coast, medieval Avars and Otzi the Iceman. We also launched the first AI assistant available to 23.me plus premium customers, Dana, to help find and understand Ancestry and Health reports. These developments continue to result in increased growth and improved retention rates for the 23.me subscription services, In line with our focus on shifting to higher margin recurring revenue streams, we were able to more than double the percentage of revenue that is recurring, with more than 21% of total revenue in Q2 versus only 9% in the prior year quarter. Speaker 200:07:14On the research front, we presented a new study using 23.me research data that builds on previous research and indicates that drug targets supported by human genetics are 2 to 3 times more likely to succeed. With the scale of our data and using proprietary gene mapping algorithms, we not only find many novel insights, but can also increase the relative rate of success even further. We also published one of the largest and most diverse genetic studies of sickle cell traits in collaboration with the National Institute of Health and Johns Hopkins University School of Medicine. Important research such as these and the caliber of research organizations we are working with demonstrate the value of 23. Me database to continue discovering new insights into disease that benefit the entire population. Speaker 200:08:04Turning to therapeutics. In Q2, we presented data on our 23andme61023andme1473 clinical stage immuno oncology programs at the European Society For Medical Oncology Annual Meeting. The data show that 23me 610 monotherapy demonstrates preliminary evidence of clinical benefit in clear cell renal cell carcinoma with one confirmed partial patient response. Further, the data show higher tumor expression of CD200 and human genetics correlated with increased clinical benefit indicating CD200 could be a promising biomarker. We also saw 23me1473 inhibit tumor growth in a patient derived mouse model of non small cell lung cancer. Speaker 200:08:55While we are winding down this part of our business, we will continue to leverage 23.me's unmatched genetic community with over 15,000,000 customers to pursue collaborations with pharmaceutical and biotech companies as part of our mission to help people benefit from the human genome. These collaborations run across several areas, including drug target discovery and validation, clinical trial recruitment efforts and disease awareness among others. 23me Therapeutics was established to improve people's health by harnessing the power of human germline genetic data at scale. Over the last 9 years, we have taken major step forward leveraging the 23me database to identify a large number of potential therapeutic targets and to develop unique and valuable insights. We have engaged in a highly productive 6 year collaboration with a major pharmaceutical collaborator, GSK, and have advanced 2 in house immuno oncology assets into the clinic with positive results. Speaker 200:09:53We are proud of the work we've done and we look forward to advancing it further with collaborative efforts. And with that, I will turn it over to Joe to walk through the numbers. Speaker 300:10:03Thank you, Anne. During the quarter, we continued to make strides towards our goal of operating a cash flow positive consumer business, improving our GAAP net loss by 21% and adjusted EBITDA by 26% for the same period in the prior year. Revenue for the quarter was $44,000,000 a decrease of approximately 12% over the same period in the prior year. This is due to lower consumer services revenue, driven mainly by lower PGS kit sales volume and telehealth orders, as well as lower research services revenue as the GSK collaboration exclusive discovery term concluded in July 2023. These decreases were partially mitigated by growth in membership services revenue, driven by increased upgrades from other tiers of PGS kits and sustained growth in our customer renewal rates. Speaker 300:10:58Revenue from consumer services, which includes PGS, telehealth and membership services, represented approximately 99% of total revenue for fiscal year 2025 Q2. Research services revenue accounted for approximately 1% of total revenue for fiscal year 2025q2. As a reminder, we expect to begin recognizing revenue in the second half of the fiscal year twenty twenty five from the GSK data license announced last October. Our gross profit for the quarter was $22,000,000 representing a 3% increase over the same period in the prior year. The increase was driven primarily by growth in our high margin membership services, which more than offset the lower consumer and research services revenue mentioned previously. Speaker 300:11:50Operating expenses for fiscal 2025Q2 were $84,000,000 compared to $101,000,000 for the same period in the prior year. The decrease in operating expenses for the quarter was driven by lower personnel related expenses, including non cash stock based compensation expenses, following workforce reductions in the current and prior quarters and the disposition of Lemonade Health Limited in the UK in August 2023. The improvement also reflects lower therapeutics related R and D spend as we opted for royalty on several GSK partner programs, resulting in a significant reduction of GSK collaboration expenses compared to the prior year quarter, while retaining upside in those programs. Looking at the bottom line, net loss for the quarter was $59,000,000 compared to a net loss of $75,000,000 for the same period in the prior year. The improvement in 2nd quarter net loss was driven mainly by savings and operating expenses as just discussed. Speaker 300:12:55Next, our adjusted EBITDA. For details on how we define adjusted EBITDA, as well as the corresponding reconciliations to GAAP, please see our earnings press release. Total adjusted EBITDA deficit for the 2nd quarter was a loss of $33,000,000 compared to a loss of $45,000,000 for the same period in the prior year. The improvement in adjusted EBITDA was primarily due to lower R and D and personnel related expenses and improvements in our consumer services gross profit, partially offset by lower research services gross profit. We ended the quarter with cash and cash equivalents of $127,000,000 compared to $216,000,000 as of March 31, 2024. Speaker 300:13:43Our financial statements for this quarter include a going concern disclosure. The company will need additional liquidity to fund its necessary expenditures and financial commitments for the 12 months after the date our 10 Q was filed, resulting in the going concern disclosure. To improve our financial condition and liquidity position, the company is working to execute its business plan, managing ongoing operational expenses and implementing cost cutting measures, as well as considering raising additional capital. The business restructuring we announced yesterday is expected to substantially reduce our operating expenses. We expect annualized cost savings of at least $35,000,000 per year and we expect to incur approximately $12,000,000 in costs and expenses primarily related to one time severance, transition and termination related costs. Speaker 300:14:41We believe these efforts will help improve our financial condition and liquidity position to extend our cash runway. Before I conclude, I also want to mention that we recently regained NASDAQ listing compliance with the minimum closing bid price and the majority independent board and various board committee requirements. Looking ahead, we are focused on getting 23andme on a more sustainable path towards positioning the company for the future. We'll now turn the call to Q and A. Speaker 100:15:11Thank you, Joe. We have a few questions from investors and shareholders that came in through our Q and A platform that we use through SAVE Technology. The first question is for Anne. What is the plan for recovery? Speaker 200:15:27Thanks, Katie. Good question. So a number of different areas I want to chat about. So first, what Joe referenced, regaining compliance was a top priority for us. So we did that with the new Board, the share price, reverse stock split. Speaker 200:15:43So regaining compliance was a high priority for us. 2nd, on becoming more sustainable, has been a top priority. And that was really achieved with now deprioritizing therapeutics and committing to we are going to either shut down or out license those assets, as well as cutting expenses, so dramatically reducing all of our costs. 3rd was, as I mentioned, was, out licensing our therapeutics programs and focusing there. And 4th is now on growing our business. Speaker 200:16:18And the areas that we're focused on growing the business are really on subscriptions and continuing to really encourage our customers to take advantage of all the value that we are putting into the subscription products, like the additional health reports, the additional fun features like historical matches, getting more and more customers, recognizing the value that are in a subscription product, as well as now really focusing on the database opportunities. And we see an increasing interest from the therapeutics world on using genetics in discovery and in clinical trials. And we are focused on making sure that we are front and center there and are the leading opportunity for the pharmaceutical industry and clinical trials that they are leveraging 23 andMe and those opportunities. Speaker 100:17:07Great. Thanks, Ann. The second question is for you, Joe. Why was the 1.20 reverse stock split necessary? Speaker 300:17:17Thank you, Katie. We completed the reverse stock split transaction in October of this year to regain compliance with the NASDAQ listing requirement that 23 and me have a bid price of at least $1 per share. The reverse stock split was approved by the stockholders at our most recent annual meeting of stockholders. And the good news is we've subsequently received notification from NASDAQ after the reverse stock split that we are now in compliance with this listing requirement. Speaker 100:17:47Great. Thank you, Joe. The third question, due to the nature of the industry and your current business model, what steps are being taken to make it profitable? I'll hand that to you, Joe. Speaker 300:17:59Thank you again, Katie. We are continuing to prioritize our subscription products with recurring revenue to reflect the ongoing value that we provide our customers and growing our research partnerships and collaborations. We are also continuing to look at reducing our cost base. And as we announced the restructuring yesterday of headcount and pausing on our therapeutic assets that we have in clinical trials, all of which will result in significant annual cost savings. Speaker 100:18:29Great. And the last question, I'll direct to Anne. What goals are you looking to complete in 2025? Speaker 200:18:37Well, after getting through today and some of the restructuring plans that we have announced with therapeutics as well as with cutting costs, the three areas that we're really focused on is, as I mentioned, growing subscriptions and really continuing to provide value for our customers in the subscription product and more and more, enabling customers to recognize the value that's there and encouraging them to be part of the subscription. 2nd is the database business. And as I said, there's increasing evidence showing that genetic utilization in the clinical trial and the drug discovery process is going to increase outcomes or increase the likelihood of success. So focusing on developing those products so that we can serve the industry. And last is out licensing our therapeutic program so that they can continue to be developed and eventually really be great products that could benefit customers. Speaker 100:19:35Great. Thank you. That completes the top questions we'll be answering. I'm going to hand it back to the operator now. Operator00:19:45Thank you all for joining today's conference. You may all disconnect.Read morePowered by Conference Call Audio Live Call not available Earnings Conference Call23andMe Q2 202500:00 / 00:00Speed:1x1.25x1.5x2x Earnings DocumentsPress Release(8-K)Quarterly report(10-Q) 23andMe Earnings Headlines23andMe to close San Francisco office, warns 250 employees of possible layoffsMay 7 at 2:19 AM | msn.com23andMe to close San Francisco office, warns 250 employees of possible layoffsMay 7 at 2:19 AM | msn.comThink NVDA’s run was epic? You ain’t seen nothin’ yetAsk most investors and they’ll probably tell you Nvidia is the undisputed AI stock of the decade. In 2023, it surged 239%. And in 2024, it soared another 171% on the year… But what if I told you there was a way to target those types of “peak Nvidia” profit opportunities in 24 hours or less?May 7, 2025 | Timothy Sykes (Ad)23andMe Expects Multiple Bids for Genetic Data, Lawyer SaysMay 7 at 2:19 AM | bloomberg.com23andMe Expects Multiple Bids for Genetic Data, Lawyer SaysMay 7 at 2:19 AM | bloomberg.comTech Talk: What happens to your data when 23andMe sells it to the highest bidder?May 3, 2025 | msn.comSee More 23andMe Headlines Get Earnings Announcements in your inboxWant to stay updated on the latest earnings announcements and upcoming reports for companies like 23andMe? Sign up for Earnings360's daily newsletter to receive timely earnings updates on 23andMe and other key companies, straight to your email. Email Address About 23andMe23andMe (NASDAQ:ME) Holding Co. operates as a consumer genetics testing company. The company operates in two segments, Consumer & Research Services and Therapeutics. The Consumer & Research Services segment provides a suite of genetic reports, including information on customers' genetic ancestral origins, personal genetic health risks, and chances of passing on certain rare carrier conditions to their children, as well as reports on how genetics can impact responses to medications. This segments also operates Lemonaid telehealth platform to access affiliated licensed healthcare professionals for medical consultation and treatment for various common conditions; and offers research services. The Therapeutics segment focuses on the drug development; and discovery and development of novel therapies to enhance patient lives across various therapeutic areas, including oncology, respiratory, and cardiovascular diseases, as well as offers out-licensing intellectual property associated with identified drug targets related to drug candidates under clinical development. The company's therapeutics product portfolio comprises 23ME-00610 (P006), a humanized monoclonal antibody, which is in phase 1/2a clinical trials to interfere with the ability of CD200R1 to interact with CD200 in cancer cells; and GSK6097608, an antibody that targets CD96 for attenuating T and NK cell anti-tumor immune responses. The company was incorporated in 2006 and is headquartered in South San Francisco, California.View 23andMe ProfileRead more More Earnings Resources from MarketBeat Earnings Tools Today's Earnings Tomorrow's Earnings Next Week's Earnings Upcoming Earnings Calls Earnings Newsletter Earnings Call Transcripts Earnings Beats & Misses Corporate Guidance Earnings Screener Earnings By Country U.S. Earnings Reports Canadian Earnings Reports U.K. Earnings Reports Latest Articles Archer Stock Eyes Q1 Earnings After UAE UpdatesFord Motor Stock Rises After Earnings, But Momentum May Not Last Broadcom Stock Gets a Lift on Hyperscaler Earnings & CapEx BoostPalantir Stock Drops Despite Stellar Earnings: What's Next?Is Eli Lilly a Buy After Weak Earnings and CVS-Novo Partnership?Is Reddit Stock a Buy, Sell, or Hold After Earnings Release?Warning or Opportunity After Super Micro Computer's Earnings Upcoming Earnings Coinbase Global (5/8/2025)Monster Beverage (5/8/2025)Brookfield (5/8/2025)Anheuser-Busch InBev SA/NV (5/8/2025)ConocoPhillips (5/8/2025)Cheniere Energy (5/8/2025)McKesson (5/8/2025)Shopify (5/8/2025)Enbridge (5/9/2025)Petróleo Brasileiro S.A. - Petrobras (5/12/2025) Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. 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There are 4 speakers on the call. Operator00:00:00Good day and thank you for standing by. Welcome to the 23 andMe Fiscal Year 2025 Second Quarter Earnings Call. At this time, all participants are in a listen only mode. Please be advised that this call is being recorded. I would now like to turn the conference over to your speaker for today, Katie Watson, Vice President of Communications. Operator00:00:21Please go ahead. Speaker 100:00:27Thank you. Before we begin, I encourage everyone to go to investors. 23me.com to find the press release we issued earlier today reporting our financial results for the Q2 of fiscal 2025. A replay of today's webcast will also be available on our website. Please note that certain statements made during this call regarding matters that are not historical facts, including but not limited to management's outlook or predictions for future periods are forward looking statements. Speaker 100:00:58These statements are based solely on information that is now available to us. We encourage you to review the section entitled Forward Looking Statements in our press release, which applies to this call. Also, please refer to our SEC filings, which can be found on our website and the SEC's website for a discussion of numerous factors that may impact our future performance. We also discuss certain non GAAP measures. Important information on our use of these measures and reconciliations to U. Speaker 100:01:27S. GAAP may be found in our earnings release. Joining us on our call today are Ann Wojcicki, our Chief Executive Officer and Co Founder and Jo Selzavage, our Chief Financial and Accounting Officer. I'd now like to turn the call over to Anne. Speaker 200:01:43Thanks, Katie. Hello, everyone. I'd like to start today's call by addressing recent developments at the company and then we'll get into the Q2. In late October, 23andme reconstituted our Board of Directors with the appointment of 3 new independent directors. We are pleased that these accomplished and experienced executives who are committed to our mission could jump in immediately. Speaker 200:02:07We have fulfilled our obligations as a public company and regain compliance with the NASDAQ listing standards by reconstituting our Board and executing a reverse stock split. In addition, yesterday, we announced that 23. Me is undertaking a business restructuring to streamline operations, reduce costs and position the company for long term success. Under this restructuring, we are discontinuing further development of all therapeutic programs and reducing our workforce by approximately 40%. Joe will discuss the financial impact of the restructuring in his prepared remarks. Speaker 200:02:45We continue to believe in the promise shown by our clinical stage oncology assets and our preclinical immunology pipeline. As we immediately start the wind down process for the therapeutics division, we will be actively exploring a range of strategic alternatives for our therapeutics pipeline that will enable their continued development outside of 23andme. We intend to continue supporting the collection of data and monitoring of patients in our clinical trials, while the strategic alternative process and wind down are completed. These are difficult but necessary actions that we believe begin putting 23andme on a more sustainable path and positioning the company for the future. We appreciate the dedication and contributions of our team to our mission and are committed to supporting the impact of employees through this transition. Speaker 200:03:37We also remain deeply grateful to the patients, investigators and study staff for their participation in our clinical trials and will work to ensure development efforts can continue for the benefit of patients. Now I'll turn to the Q2 of our fiscal year 2025. We made considerable strides in our key objective of becoming a sustainable cash flow positive company, while remaining committed to our goal of helping millions of people live longer healthier lives. The team continues to leverage the full spectrum of 23 andMe platform to deliver integrated preventive health services and genetic insights. We made our Speaker 300:04:17total health membership service a comprehensive longevity Speaker 200:04:17platform combining advanced exome sequencing, a comprehensive longevity platform combining advanced exome sequencing, lab tests and guidance from clinicians specifically trained in genetics available to our entire customer base. We believe the future of preventive health is understanding your complete health picture, including genetics, lab testing, family health history and other data to help derive a truly personalized health plan. 23andme made significant progress in Q2, bringing the power of our research, genetic insight and telehealth platform to serve critical consumer needs. As part of our focus on prevention and longevity, we launched a number of weight management initiatives in Q2. Studies estimate that BMI is 40% to 70% influenced by genetics and that elevated BMI is associated with up to 9 fewer years lived in good health. Speaker 200:05:14A few highlights. We launched and enrolled thousands of participants in a new study to understand how genetics can impact GLP-one efficacy, side effects and length of treatment. We launched a new genetic report on emotional eating utilizing 23andme's polygenic riskScore technology for 23andme plus premium subscribers. Emotional eating impacts up to 60% of people with a high BMI and knowing this can inform weight management approaches. We also launched a GLP-one weight loss telehealth membership on the Lemonade Health platform that enables members to be prescribed and receive brand name or compounded semaglutide medications. Speaker 200:06:01These medications can be life changing and an important tool for prevention and longevity and offering our customers access to them in a convenient cost effective manner is consistent with our mission. We continue to improve and add to 23. Me's market leading ancestry composition and historical matches features with new regions for Germanic Europe, Scandinavia and Japan and new historical matches, our subscription only feature, with historical figures from the medieval Swahili Coast, medieval Avars and Otzi the Iceman. We also launched the first AI assistant available to 23.me plus premium customers, Dana, to help find and understand Ancestry and Health reports. These developments continue to result in increased growth and improved retention rates for the 23.me subscription services, In line with our focus on shifting to higher margin recurring revenue streams, we were able to more than double the percentage of revenue that is recurring, with more than 21% of total revenue in Q2 versus only 9% in the prior year quarter. Speaker 200:07:14On the research front, we presented a new study using 23.me research data that builds on previous research and indicates that drug targets supported by human genetics are 2 to 3 times more likely to succeed. With the scale of our data and using proprietary gene mapping algorithms, we not only find many novel insights, but can also increase the relative rate of success even further. We also published one of the largest and most diverse genetic studies of sickle cell traits in collaboration with the National Institute of Health and Johns Hopkins University School of Medicine. Important research such as these and the caliber of research organizations we are working with demonstrate the value of 23. Me database to continue discovering new insights into disease that benefit the entire population. Speaker 200:08:04Turning to therapeutics. In Q2, we presented data on our 23andme61023andme1473 clinical stage immuno oncology programs at the European Society For Medical Oncology Annual Meeting. The data show that 23me 610 monotherapy demonstrates preliminary evidence of clinical benefit in clear cell renal cell carcinoma with one confirmed partial patient response. Further, the data show higher tumor expression of CD200 and human genetics correlated with increased clinical benefit indicating CD200 could be a promising biomarker. We also saw 23me1473 inhibit tumor growth in a patient derived mouse model of non small cell lung cancer. Speaker 200:08:55While we are winding down this part of our business, we will continue to leverage 23.me's unmatched genetic community with over 15,000,000 customers to pursue collaborations with pharmaceutical and biotech companies as part of our mission to help people benefit from the human genome. These collaborations run across several areas, including drug target discovery and validation, clinical trial recruitment efforts and disease awareness among others. 23me Therapeutics was established to improve people's health by harnessing the power of human germline genetic data at scale. Over the last 9 years, we have taken major step forward leveraging the 23me database to identify a large number of potential therapeutic targets and to develop unique and valuable insights. We have engaged in a highly productive 6 year collaboration with a major pharmaceutical collaborator, GSK, and have advanced 2 in house immuno oncology assets into the clinic with positive results. Speaker 200:09:53We are proud of the work we've done and we look forward to advancing it further with collaborative efforts. And with that, I will turn it over to Joe to walk through the numbers. Speaker 300:10:03Thank you, Anne. During the quarter, we continued to make strides towards our goal of operating a cash flow positive consumer business, improving our GAAP net loss by 21% and adjusted EBITDA by 26% for the same period in the prior year. Revenue for the quarter was $44,000,000 a decrease of approximately 12% over the same period in the prior year. This is due to lower consumer services revenue, driven mainly by lower PGS kit sales volume and telehealth orders, as well as lower research services revenue as the GSK collaboration exclusive discovery term concluded in July 2023. These decreases were partially mitigated by growth in membership services revenue, driven by increased upgrades from other tiers of PGS kits and sustained growth in our customer renewal rates. Speaker 300:10:58Revenue from consumer services, which includes PGS, telehealth and membership services, represented approximately 99% of total revenue for fiscal year 2025 Q2. Research services revenue accounted for approximately 1% of total revenue for fiscal year 2025q2. As a reminder, we expect to begin recognizing revenue in the second half of the fiscal year twenty twenty five from the GSK data license announced last October. Our gross profit for the quarter was $22,000,000 representing a 3% increase over the same period in the prior year. The increase was driven primarily by growth in our high margin membership services, which more than offset the lower consumer and research services revenue mentioned previously. Speaker 300:11:50Operating expenses for fiscal 2025Q2 were $84,000,000 compared to $101,000,000 for the same period in the prior year. The decrease in operating expenses for the quarter was driven by lower personnel related expenses, including non cash stock based compensation expenses, following workforce reductions in the current and prior quarters and the disposition of Lemonade Health Limited in the UK in August 2023. The improvement also reflects lower therapeutics related R and D spend as we opted for royalty on several GSK partner programs, resulting in a significant reduction of GSK collaboration expenses compared to the prior year quarter, while retaining upside in those programs. Looking at the bottom line, net loss for the quarter was $59,000,000 compared to a net loss of $75,000,000 for the same period in the prior year. The improvement in 2nd quarter net loss was driven mainly by savings and operating expenses as just discussed. Speaker 300:12:55Next, our adjusted EBITDA. For details on how we define adjusted EBITDA, as well as the corresponding reconciliations to GAAP, please see our earnings press release. Total adjusted EBITDA deficit for the 2nd quarter was a loss of $33,000,000 compared to a loss of $45,000,000 for the same period in the prior year. The improvement in adjusted EBITDA was primarily due to lower R and D and personnel related expenses and improvements in our consumer services gross profit, partially offset by lower research services gross profit. We ended the quarter with cash and cash equivalents of $127,000,000 compared to $216,000,000 as of March 31, 2024. Speaker 300:13:43Our financial statements for this quarter include a going concern disclosure. The company will need additional liquidity to fund its necessary expenditures and financial commitments for the 12 months after the date our 10 Q was filed, resulting in the going concern disclosure. To improve our financial condition and liquidity position, the company is working to execute its business plan, managing ongoing operational expenses and implementing cost cutting measures, as well as considering raising additional capital. The business restructuring we announced yesterday is expected to substantially reduce our operating expenses. We expect annualized cost savings of at least $35,000,000 per year and we expect to incur approximately $12,000,000 in costs and expenses primarily related to one time severance, transition and termination related costs. Speaker 300:14:41We believe these efforts will help improve our financial condition and liquidity position to extend our cash runway. Before I conclude, I also want to mention that we recently regained NASDAQ listing compliance with the minimum closing bid price and the majority independent board and various board committee requirements. Looking ahead, we are focused on getting 23andme on a more sustainable path towards positioning the company for the future. We'll now turn the call to Q and A. Speaker 100:15:11Thank you, Joe. We have a few questions from investors and shareholders that came in through our Q and A platform that we use through SAVE Technology. The first question is for Anne. What is the plan for recovery? Speaker 200:15:27Thanks, Katie. Good question. So a number of different areas I want to chat about. So first, what Joe referenced, regaining compliance was a top priority for us. So we did that with the new Board, the share price, reverse stock split. Speaker 200:15:43So regaining compliance was a high priority for us. 2nd, on becoming more sustainable, has been a top priority. And that was really achieved with now deprioritizing therapeutics and committing to we are going to either shut down or out license those assets, as well as cutting expenses, so dramatically reducing all of our costs. 3rd was, as I mentioned, was, out licensing our therapeutics programs and focusing there. And 4th is now on growing our business. Speaker 200:16:18And the areas that we're focused on growing the business are really on subscriptions and continuing to really encourage our customers to take advantage of all the value that we are putting into the subscription products, like the additional health reports, the additional fun features like historical matches, getting more and more customers, recognizing the value that are in a subscription product, as well as now really focusing on the database opportunities. And we see an increasing interest from the therapeutics world on using genetics in discovery and in clinical trials. And we are focused on making sure that we are front and center there and are the leading opportunity for the pharmaceutical industry and clinical trials that they are leveraging 23 andMe and those opportunities. Speaker 100:17:07Great. Thanks, Ann. The second question is for you, Joe. Why was the 1.20 reverse stock split necessary? Speaker 300:17:17Thank you, Katie. We completed the reverse stock split transaction in October of this year to regain compliance with the NASDAQ listing requirement that 23 and me have a bid price of at least $1 per share. The reverse stock split was approved by the stockholders at our most recent annual meeting of stockholders. And the good news is we've subsequently received notification from NASDAQ after the reverse stock split that we are now in compliance with this listing requirement. Speaker 100:17:47Great. Thank you, Joe. The third question, due to the nature of the industry and your current business model, what steps are being taken to make it profitable? I'll hand that to you, Joe. Speaker 300:17:59Thank you again, Katie. We are continuing to prioritize our subscription products with recurring revenue to reflect the ongoing value that we provide our customers and growing our research partnerships and collaborations. We are also continuing to look at reducing our cost base. And as we announced the restructuring yesterday of headcount and pausing on our therapeutic assets that we have in clinical trials, all of which will result in significant annual cost savings. Speaker 100:18:29Great. And the last question, I'll direct to Anne. What goals are you looking to complete in 2025? Speaker 200:18:37Well, after getting through today and some of the restructuring plans that we have announced with therapeutics as well as with cutting costs, the three areas that we're really focused on is, as I mentioned, growing subscriptions and really continuing to provide value for our customers in the subscription product and more and more, enabling customers to recognize the value that's there and encouraging them to be part of the subscription. 2nd is the database business. And as I said, there's increasing evidence showing that genetic utilization in the clinical trial and the drug discovery process is going to increase outcomes or increase the likelihood of success. So focusing on developing those products so that we can serve the industry. And last is out licensing our therapeutic program so that they can continue to be developed and eventually really be great products that could benefit customers. Speaker 100:19:35Great. Thank you. That completes the top questions we'll be answering. I'm going to hand it back to the operator now. Operator00:19:45Thank you all for joining today's conference. You may all disconnect.Read morePowered by