NASDAQ:RLMD Relmada Therapeutics Q1 2024 Earnings Report $7.35 -0.06 (-0.81%) Closing price 05/5/2026 04:00 PM EasternExtended Trading$7.38 +0.04 (+0.48%) As of 05/5/2026 07:53 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. ProfileEarnings HistoryForecast Relmada Therapeutics EPS ResultsActual EPS-$0.72Consensus EPS -$0.90Beat/MissBeat by +$0.18One Year Ago EPSN/ARelmada Therapeutics Revenue ResultsActual RevenueN/AExpected RevenueN/ABeat/MissN/AYoY Revenue GrowthN/ARelmada Therapeutics Announcement DetailsQuarterQ1 2024Date5/8/2024TimeN/AConference Call DateWednesday, May 8, 2024Conference Call Time4:30PM ETUpcoming EarningsRelmada Therapeutics' Q1 2026 earnings is estimated for Monday, May 11, 2026, based on past reporting schedules, with a conference call scheduled at 4:30 PM ET. Check back for transcripts, audio, and key financial metrics as they become available.Q1 2026 Earnings ReportConference Call ResourcesConference Call AudioConference Call TranscriptPress Release (8-K)Quarterly Report (10-Q)Earnings HistoryCompany ProfilePowered by Relmada Therapeutics Q1 2024 Earnings Call TranscriptProvided by QuartrMay 8, 2024 ShareLink copied to clipboard.Key Takeaways Under the revised RELIANCE 2 (Study 302) and RELITE (Study 304) Phase III programs for adjunctive MDD, Ramada is enrolling ~300 patients each, has implemented stringent screening (raising screen failure to ~80%) to curb placebo response, and expects top-line data for RELIANCE 2 in H2 2024. Ramada’s novel modified-release psilocybin program is set to initiate a single ascending dose Phase I trial in obese volunteers in H1 2024 to define PK, safety and tolerability, with Phase IIa proof-of-concept data (PLANET 2a) anticipated in H1 2025 after promising preclinical metabolic results. In Q1 2024, research & development expenses fell to $13.3 million (from $15.9 million in Q1 2023), general & administrative expenses dropped to $9.7 million (from $12.3 million), and net loss narrowed to $21.8 million ($0.72/share) versus $26.3 million ($0.87/share). As of March 31, 2024, cash, cash equivalents and short-term investments totaled $83.6 million, providing sufficient financial runway into 2025 to support ongoing clinical programs. AI Generated. May Contain Errors.Conference Call Audio Live Call not available Earnings Conference CallRelmada Therapeutics Q1 202400:00 / 00:00Speed:1x1.25x1.5x2xTranscript SectionsPresentationParticipantsPresentationSkip to Participants Operator00:00:02Good afternoon, ladies and gentlemen, and welcome to the Relmada Therapeutics Inc. first quarter 2024 financial results conference call. At this time, all lines are in listen-only mode. Following the presentation, we'll conduct a question-and-answer session. If at any time during this call you require immediate assistance, please press star zero for the operator. This call is being recorded on Wednesday, May 8th, 2024. I would now like to turn the conference over to Tim McCarthy, LifeSci Advisors. Please go ahead. Tim McCarthyManaging Director and Relationship Manager at LifeSci Advisors00:00:38Thank you, Colin, and thank you all for joining us this afternoon. With me on today's call are Chief Executive Officer Sergio Traversa and Chief Financial Officer Maged Shenouda. This afternoon, Relmada issued a press release providing a business update announcing financial results for the three months ended March 31st, 2024. Please note that certain information discussed on the call today is covered under the Safe Harbors provision of the Private Securities Litigation Reform Act. We caution listeners that during this call, Relmada's management team will be making forward-looking statements. Actual results could differ materially from those stated or implied by these forward-looking statements due to risks and uncertainties associated with the company's business. Tim McCarthyManaging Director and Relationship Manager at LifeSci Advisors00:01:15These forward-looking statements are qualified by the cautionary statements contained in Relmada's press release issued today and the company's SEC filings, including in the annual report on Form 10-K for the year ended December 31st, 2023, and subsequent filings. This conference call also contains time-sensitive information that is accurate only as of the date of this live broadcast, May 8th, 2024. Relmada undertakes no obligation to revise or update any forward-looking statements to reflect events or circumstances after the date of this conference call. Now I would like to turn the call over to Sergio. Sergio? Sergio TraversaCEO at Relmada Therapeutics00:01:53Thank you, Tim, as always, and good afternoon to everyone, and welcome to the Relmada first quarter 2024 conference call. We continue to achieve meaningful progress in the advancement of our ongoing phase 3 program for REL-1017 in Major Depressive Disorder, MDD, as well as in the promising preclinical novel psilocybin program, all of which I will briefly cover today. Following this, Maged will review our first quarter 2024 financial results, and then we will take your questions. Let's begin with an update on the late-stage phase 3 program for REL-1017. As a reminder, Relmada is focused on developing REL-1017 as an adjunctive treatment for MDD. We previously executed important revisions to Reliance II, the ongoing Study 302, which is a phase 3, two-arm, placebo-controlled pivotal study evaluating REL-1017 25 milligrams for adjunctive MDD. These modifications were aimed at controlling placebo response and improving the profile of patients enrolled. Sergio TraversaCEO at Relmada Therapeutics00:03:07The amended Study 302 protocol has been implemented across all of our clinical sites. Enrollment continues to advance, and our ability to leverage our close relationship with the study sites continues to play a critical role. Moreover, the ongoing initiative we put in place to drive trial awareness with prospective patients is also generating positive results. As we said on our last call, we are evaluating the quality and productivity of sites on a real-time basis and making tweaks as appropriate. As a reminder, we plan to enroll approximately 300 patients into Reliance II. Based on our current projection, we continue to expect Reliance II to be completed with top-line data anticipated in the second half of this year. We are also continuing to enroll those patients in our second phase 3 trial for REL-1017, Relight, or Study 304 that also has a planned enrollment of approximately 300 patients. Sergio TraversaCEO at Relmada Therapeutics00:04:11Like Reliance II, Relight is a randomized, double-blind, placebo-controlled four-week trial evaluating the efficacy and safety of REL-1017 as an adjunctive treatment of MDD in patients experiencing inadequate response to ongoing background antidepressant treatment. The primary endpoint of both studies is the same: the change in the MADRS total score from baseline to day 28 for REL-1017 as compared to placebo. I would like to emphasize again that we have made meaningful revisions to our screening and enrollment processes in order to ensure that we have patients that meet all of the qualifying criteria within our desired patient profile. To this end, we are now executing on a comprehensive adjudication process through which we require medical and pharmacy records for all patients enrolled in Reliance II and Relight. Sergio TraversaCEO at Relmada Therapeutics00:05:12Given this, the screen failure rate in this study has increased to approximately 80% versus approximately 50% in Reliance I and Reliance III, our previously completed phase 3 trials of REL-1017. However, we are highly confident that these changes will substantially enhance the probability of success of the current studies. I would also like to highlight that we have completed all of the necessary preclinical manufacturing and phase 1 studies required for a potential REL-1017 NDA filing, and our current focus is on executing the remaining 2 phase 3 studies, 302 and 304. Moving on now to the promising novel modified release psilocybin program. Sergio TraversaCEO at Relmada Therapeutics00:06:07We continue to anticipate the initiation of a single-ascending dose phase 1 trial in obese patients in the first half of this year to define the pharmacokinetic safety and tolerability profile of our modified release psilocybin formulation in this population, followed by a phase 2A trial to establish clinical proof of concept. Data from the planned 2A study is anticipated in the first half of 2025. These planned studies will build on the compelling preclinical data that were presented in a poster presentation at last November's AASLD meeting, the liver conference. These results showed the beneficial effect of low chronic dose psilocybin on multiple metabolic parameters in a rodent model of metabolic dysfunction-associated steatotic liver disease, or MASLD. Based on this data, low-dose psilocybin could improve lipids and glucose with potential for fewer side effects over other investigative treatment approaches such as GLP-1 glucagon and GIP. Sergio TraversaCEO at Relmada Therapeutics00:07:22So to summarize our multiple upcoming key milestones over the next 12-18 months, we anticipate the ongoing Reliance II study to be completed with top-line data in the second half of this year. In addition, we anticipate initiating a phase 1 clinical trial for our modified release formulation with psilocybin before the end of the current quarter. Lastly, while Maged will provide a detailed review of our financials, I would like to highlight that we continue to advance our pipeline for a position of significant financial strength with cash on hand to take us comfortably into 2025. I will now turn the call over to Maged to review our first quarter financial results. Maged? Analyst at Leerink Partners00:08:09Thank you, Sergio. Today, we issued a press release announcing our business and financial results for the three months ending March 31, 2024, which I will now review. For the first quarter ending March 31, 2024, total research and development expense was approximately $13.3 million as compared to $15.9 million for the comparable period of 2023, a decrease of approximately $2.6 million. The decrease was primarily associated with the completion of the long-term open-label study, Study 310, in the third quarter of 2023, as well as Reliance I and III. The non-cash charge related to stock-based compensation for R&D totaled $1.7 million in the most recently completed first quarter. Total general and administrative expense for the first quarter ending March 31, 2024, was approximately $9.7 million as compared to $12.3 million for the comparable period of 2022, a decrease of approximately $2.6 million. Analyst at Leerink Partners00:09:18The decrease was primarily driven by a decrease in stock-based compensation expense. The non-cash charge related to stock-based compensation for GAAP totaled $6.6 million in the most recently completed first quarter. For the first quarter ending March 31, 2024, the net loss was $21.8 million or $0.72 per basic and diluted share compared with a net loss of $26.3 million or $0.87 per basic and diluted share in the comparable period of 2023. As of March 31, 2024, we have cash, cash equivalents, and short-term investments of approximately $83.6 million compared to $96.3 million as of December 31, 2023. Cash used in operations in the first quarter of 2023 was $13 million. Based on our clinical development plan, our current cash position provides us with comfortable runway into 2025. I will now ask the operator to please open up the call for questions. Operator? Operator00:10:29Thank you. Ladies and gentlemen, we'll now begin the question-and-answer session. If you'd like to ask a question, please press star, followed by one. If you'd like to withdraw your question, please press star, followed by two. If you're using a handset, please lift the handset before pressing any keys. Your first question comes from Mark Goodman from Leerink Partners. Mark, please go ahead. Analyst at Leerink Partners00:10:55Hi, this is Basma for Mark. I had a question about the Reliance and Relight trials, the ongoing Reliance and Relight trials. You actually mentioned something that you were monitoring the trials, monitoring the looking at the blinded data before in the previous call, in the fourth Q earnings call. Can you provide some color about those kind of blinded data from what you see right now from the Reliance and Relight if you compare to the prior trial that had larger placebo response? Do you see any similarities? Do you see any difference? Just to give us some color about the strategy that you implemented to reduce the placebo response. Thank you. Sergio TraversaCEO at Relmada Therapeutics00:11:45Yeah, sure. And thanks for the question. I'll give you the top-down answer, and then we have Dr. Andrew Cutler. He's our clinical advisor on the call. We'll provide a little bit more details about this aspect. Well, first, let me say something about the blinded data, right? There is absolutely no way to guess from the blinded data the outcome of a clinical trial. And we experienced that in the last 2 trials that we had. So the help that we can get or everybody can get from monitoring the blinded data is only and exclusively to see if there is something that it's not that doesn't make—I can't find the right word, but that is not consistent, right? Sergio TraversaCEO at Relmada Therapeutics00:12:40For a given example, if there are individual patients with the MADRS scores week over week that goes up and down, or we call it zigzag, then you know that there is something that is not right. It can be the patient or it can be the site. But usually, a patient that responds is consistent over four weeks, and if it doesn't respond, it's still consistent over the four weeks. So if you see a zigzag, that's a signal that something is not consistent. And so we take a look to that, to the patients, and mostly to the site. So that's really the only help that you can get from the blinded data. But it is important, right, to continue to monitor to see that not many of these patients with this zigzag pattern get into the trial. Sergio TraversaCEO at Relmada Therapeutics00:13:28When it's in, there is nothing we can do, but we can at least revise and advise the site that something is kind of like a red flag. And Andy, you are on the call. Would you mind to provide some more details about it? Andrew CutlerClinical Advisor at Relmada Therapeutics00:13:44Yes. I absolutely agree with what Sergio said. What you look for is consistency and quality indicators. In addition to what he said about the primary, the MADRS zigzagging, you also look for consistency across different scales. The key secondary outcome, of course, being a CGI, usually that moves in the same direction as the MADRS, which is measuring depression symptoms. So you look for that. I would say also that in the previous trial, sites were allowed to enroll rather quickly without watching the quality as closely as we're doing now. And that can certainly be a problem. So we're now really being much more careful with the enrollment, not allowing a site to over-enroll patients until we've looked at the quality, monitoring the quality of each site and the trial overall. And I would say things are looking fine from that point of view at this point. Sergio TraversaCEO at Relmada Therapeutics00:14:48Thank you, And. I hope that answered your question. Analyst at Leerink Partners00:14:53Thank you. Operator00:14:56Your next question comes from Andrea Tan from Goldman Sachs. Please go ahead. Analyst at Leerink Partners00:15:02Hi, Sergio. Thanks so much for taking the question. Maybe one follow-up to your remarks right there. As you are monitoring the sites, if you do see the inconsistencies that you've just spoken about, maybe walk us through what steps then you would take to remediate those issues. And then I have 1 follow-up question. Thank you. Sergio TraversaCEO at Relmada Therapeutics00:15:23Yes. Good afternoon, Andrea. Thanks for the question. As before, I will give you the short answer, and then Andy, if you would like to provide a little bit more details. In general, well, first, do you contact the site and you discuss any details regarding patients or patients that have some inconsistency? Then you go through the whole process. Ultimately, if that becomes a pattern, you don't want to have a site that shows inconsistency enrolling 10, 20 patients because that would affect the whole trial. The ultimate measure is to close the site. Andy, I'm sure I can give you a little bit more color on this. Andrew CutlerClinical Advisor at Relmada Therapeutics00:16:13Yeah, that is well said. The most important thing is to not allow a site to continue to enroll patients and have problems like that. And so, as you know, if 1 site has too many patients, 1 or 2 sites, that can kill a trial. But also, if you do see this well, first of all, the site also knows, having run sites, the site knows now if you're looking over my shoulder and you're going to call me, it really does make them be on their best behavior, if you will, and not cut corners. But ultimately, we have closed down some sites that had quality issues. So ultimately, what you do is you just stop them from enrolling so that they don't have a chance to hurt the study. Analyst at Leerink Partners00:16:59Okay. Sergio TraversaCEO at Relmada Therapeutics00:17:00Thank you, Andrea. Analyst at Leerink Partners00:17:01Andy, can you just remind us quickly, are you planning on having an interim analysis, or is there going to be any type of mechanism in place for the DMC to recommend stopping the study early as they have in your prior trial? Sergio TraversaCEO at Relmada Therapeutics00:17:17We will have not we, but the data monitoring committee will have a look at the data at some point, very close to the end. But this is not an interim analysis because there is no statistical penalty. It's a sample reestimation. They will let us know if the sample that we have in the trial is enough to reach statistically significant or if we have to expand the trial. There is no early stop planned. Analyst at Leerink Partners00:17:52The other major function of the DMC, of course, is to monitor safety. The good news is the safety and the tolerability have looked very good. Analyst at Leerink Partners00:18:04Great. Thanks so much. Sergio TraversaCEO at Relmada Therapeutics00:18:05Thanks, And Thank you, Andrea. Operator00:18:08Your next question comes from Andrew Tsai from Jefferies. Andrew, please go ahead. Analyst at Jefferies00:18:14Hey, congrats on the progress. This is Matt calling in for Andrew. And I guess continuing with the same theme, do you have any specifics on the numbers of sites that you've had to pause, close, or been able to even reopen using your monitoring, real-time analysis? And then also, we've seen. Sergio TraversaCEO at Relmada Therapeutics00:18:35Sorry. No, maybe it's me, but I can barely hear you. Analyst at Jefferies00:18:40Okay. Can you hear me better now? Sergio TraversaCEO at Relmada Therapeutics00:18:43Oh, much better. Yeah. Thank you. Sorry for that. Analyst at Jefferies00:18:46Okay. Yeah, no problem. So yeah, I was just asking, continuing with the real-time site analysis, if you'd had any specifics on the number of sites that you've had to pause, close, or maybe even reopen? And then also, over the past year, we've seen quite a few companies that have announced delays, for instance, schizophrenia and epilepsy spaces. And are you seeing any increased level of competition in terms of funding the right MDD depression patients? And then I. Sergio TraversaCEO at Relmada Therapeutics00:19:15Well, thanks for the question. Yeah. Thank you very much for the question. So in terms of sites, right, the site selection is not like a fix that you decide 50, 60 sites at the beginning, and you finish with the same sites. It is an ongoing process. So constantly, there is a revision of sites. And some site is closed not only for quality issue, also for the competing studies or they exhausted the patient population that they can enroll into the site. So it is an ongoing. I don't have on the top of my mind a really specific number, but it's not like that at some point you do a review. It's an ongoing process. So maybe Andy, when I finish, the other answer can give you a little bit more details because he runs clinical sites. So he is more into the detail of the process. Sergio TraversaCEO at Relmada Therapeutics00:20:23The second question, would you mind to repeat it? Analyst at Jefferies00:20:27Yeah. Just the competing study. Sergio TraversaCEO at Relmada Therapeutics00:20:29The competing study, right? Analyst at Leerink Partners00:20:30Yeah, exactly. Sergio TraversaCEO at Relmada Therapeutics00:20:31Yeah. Well, there is clearly some competition out there. And mostly, I mean, usually, a site cannot or does not take on 3, 4 studies that enroll the same kind of patients. In our case, it's a little bit particular because we are doing the studies are for adjunctive treatment of depression. So that's the competition. It's much less because there are not many other programs, especially in phase 3, that enroll patients in adjunctive. We do believe there was 1 other company that finished 1sizable, big study a few weeks ago. But I do believe that the majority of their sites were outside the U.S. So there was relative competition. It was not an antidepressant anyway. We keep on hearing that the psilocybin, there are a lot of trials ongoing with psilocybin in depression. Sergio TraversaCEO at Relmada Therapeutics00:21:44That is not really a direct competitor, but still, it keeps the sites busy and is high-dose psilocybin for PTSD and MDD. So yeah, to summarize, yes, there is competition, but we are in a specific indication where the competition is much lower. Andy, would you mind to provide a little bit more color? Andrew CutlerClinical Advisor at Relmada Therapeutics00:22:12Yes. I'll answer the 2nd one first. And that is that Sergio is exactly right. At the site level, you don't want to take too many competing studies. Usually, though, the study criteria are different enough that you can do, say, two or three depression studies without significantly impairing because a patient will more clearly fit into 1 protocol than another. So as far as the first question, I don't have the exact number of sites that we've closed down offhand. But sites do close for various reasons. That's certainly true. But we have stopped enrollment at a couple of sites. I can say that. But it's not a lot, fortunately. And I think some of it is simply the process of overseeing the sites. Now, the sites know that they're being watched. They know that we're monitoring quality. Andrew CutlerClinical Advisor at Relmada Therapeutics00:23:00That often changes the behavior enough so that significant corrective action isn't necessary. Analyst at Jefferies00:23:07Got it. Yeah. That makes sense. And then I guess regarding the phase 1 Psilocybin program that you're going to be kicking off soon, can you describe the study design and what positive data would entail? Sergio TraversaCEO at Relmada Therapeutics00:23:22Yes. It's very simple. We'll start with a Phase 1, a single dose, the starting dose of Psilocybin modified release. So the interesting part is the patient population. Or technically, Phase 1, you do it in a healthy volunteer. But it's well known that Psilocybin is a relatively safe product at high dose, and we are using a dose very, very much, much lower, like 1/20th or 1/30th of the dose that is used as a psychedelic for the treatment of psychiatric diseases. So on the safety side, we feel extremely comfortable. But the indication that we'll pursue for Psilocybin is into the metabolic space, so obesity and glucose and fatty liver. So the data that we are looking for is mostly PK data in obese patients. Sergio TraversaCEO at Relmada Therapeutics00:24:25The particular is the patient population that will be obese healthy volunteers, and which we should start over the next month or 2. We said within the first half. So we are getting there. It's a short study. So the whole study will last like 3-4 months maximum. Analyst at Jefferies00:24:49Excellent. Thank you. Sergio TraversaCEO at Relmada Therapeutics00:24:51Thank you. Operator00:24:53Ladies and gentlemen, as a reminder, if you'd like to ask a question, please press star, followed by 1. Your next question comes from Louir from Mizuho. Please go ahead. Analyst at Mizuho Securities00:25:06Hi. This is Charles for Louir. I had a question about kind of the screening failure rate and if you think that's going to kind of stay at 80% throughout the study enrollment. And then also, if you could clarify if Reliance II screening failure rate was also 50% before the new protocol. Thank you. Sergio TraversaCEO at Relmada Therapeutics00:25:29Hey, Charlie. Thanks for the question. And so yeah, the screening failure, it's high, but we look at the reason for the screening failure. And there are legitimate reasons, right? Usually, it's drug-drug interaction or concomitant mostly it's concomitant medication. So yeah, these are legitimate reasons not to enroll in the study. And most of the screening failure actually come from the site. And with that said, we are in constant review, and we listen very carefully to the feedback from the sites. And there is anything that we can do to increase the enrollment rate or decrease the screening failure, but without decreasing the quality and increasing the risk of the trial, we have been doing that. So there are certain things that have been, especially on the drug-drug interaction or concomitant medication more than interaction, that have been changing over time. So that should facilitate. Sergio TraversaCEO at Relmada Therapeutics00:26:41This is a back and forth from the company and the site. So yeah, they give us the feedback, and we see patients with that characteristic that it could fit into the trial, but we cannot put it in because of the inclusion and exclusion. So we revised. And in a dialogue with the FDA, of course, we have made a few detailed revisions of the protocol over time. So we don't know what we'll do to the screening failure, but definitely, there is a chance that we could get a little better. And the second question was at the beginning. Yeah, that's a great question, but I don't have the answer on the top of my head. And the screening failure at the beginning of 3 or 2, probably there are not a lot of patients enrolled. So I don't know how much that number is meaningful. Sergio TraversaCEO at Relmada Therapeutics00:27:35But maybe Andy or Maged, if they have some more color on that, the screening failure on the Study 302 before we amended the protocol. Andrew CutlerClinical Advisor at Relmada Therapeutics00:27:47I don't believe it was quite the yeah. Go ahead, Maged. Sorry. Analyst at Leerink Partners00:27:51Go ahead, Andy. Yeah, it was certainly not quite as high. I don't want to put a number out there without confirming with our internal team. So we'll have to get back to you, so. Andrew CutlerClinical Advisor at Relmada Therapeutics00:28:03Yep. Exactly. But I would not be put off by screening failure. We're trying to find the right patients, and that's critically important. Patient selection is absolutely a source of failure in studies. Sergio TraversaCEO at Relmada Therapeutics00:28:18Okay. Thanks,. Sergio TraversaCEO at Relmada Therapeutics00:28:21Right. And sorry. Yeah. As we mentioned in some of our calls, right, 1 of the biggest changes, the amendment we made to the protocol is that there is now a requirement for medical and pharmacy records. And that's by itself increased the screening failure. But also, at the same time, you are relatively comfortable that that patient comes from a doctor that has diagnosed and prescribed medication and that the patient actually purchased the medication from the pharmacy. So the 2 things, they go together, high screening failure, but there is clearly an improvement in the risk profile of the patients enrolled. I hope that answers your question. Analyst at Mizuho Securities00:29:10Yeah. Thank you. Operator00:29:14There are no further questions at this time. I'll turn it back to Sergio for closing remarks. Sergio TraversaCEO at Relmada Therapeutics00:29:23Thank you. In summary, we continue to firmly believe that we have an approvable drug in REL-1017, and we are excited by the potential of our novel Psilocybin derivative program. We look forward to reporting on further progress with our pipeline throughout the remainder of 2024. I do remain grateful to the Relmada team for their continued hard work and dedication to executing on our mission. Also, as always, I would like to extend my sincere thanks to the patients and clinical partners involved in the REL-1017 trials for their participation in the advancement of this promising investigation on medicine through development. Thanks a lot to everyone for the attention and the interest, and looking forward to the next conference call. Operator00:30:15Ladies and gentlemen, this concludes your conference call for today. We thank you for participating and ask that you please disconnect your lines.Read moreParticipantsExecutivesAndrew CutlerClinical AdvisorSergio TraversaCEOAnalystsTim McCarthyManaging Director and Relationship Manager at LifeSci AdvisorsAnalyst at JefferiesAnalyst at Leerink PartnersAnalyst at Mizuho SecuritiesPowered by Earnings DocumentsPress Release(8-K)Quarterly report(10-Q) Relmada Therapeutics Earnings HeadlinesRelmada Therapeutics to Present NDV-01 Abstracts at AUA2026May 5 at 7:00 AM | globenewswire.comMizuho Securities Remains a Buy on Relmada Therapeutics (RLMD)April 16, 2026 | theglobeandmail.comYour book is insideThe "Sucker's Bet" Most New Options Traders Fall For Most people who try options lose money the same way. They don't know the rules. They don't know what to avoid. And they hand their account to Wall Street on a silver platter. Normally $29.97. Free today. | Profits Run (Ad)Relmada Therapeutics: 2 New Assets, 2 New 'Blockbusters'? I'd Wait And SeeMarch 30, 2026 | seekingalpha.comHere’s What Makes Mizuho Bullish on Relmada Therapeutics Inc (RLMD) StockMarch 25, 2026 | msn.comRelmada wins bullish view at Piper Sandler on cancer therapyMarch 24, 2026 | seekingalpha.comSee More Relmada Therapeutics Headlines Get Earnings Announcements in your inboxWant to stay updated on the latest earnings announcements and upcoming reports for companies like Relmada Therapeutics? Sign up for Earnings360's daily newsletter to receive timely earnings updates on Relmada Therapeutics and other key companies, straight to your email. Email Address About Relmada TherapeuticsRelmada Therapeutics (NASDAQ:RLMD) is a clinical-stage biopharmaceutical company focused on the development of novel therapies for pain and other central nervous system (CNS) disorders. The company applies a proprietary stereochemical approach to optimized drug candidates, aiming to improve safety, tolerability and efficacy profiles compared with existing treatments. Relmada’s research efforts center on modulation of NMDA receptors to address unmet needs in depression, neuropathic pain and related indications. Relmada’s lead product candidate, REL-1017 (d-methadone), is being evaluated as a potential rapid-acting and maintenance treatment for major depressive disorder, with clinical studies underway to assess its utility in both acute and long-term settings. In parallel, the company is advancing additional pipeline programs targeting neuropathic pain, including diabetic neuropathy and chemotherapy-induced peripheral neuropathy. Relmada collaborates with academic centers and contract research organizations to conduct multi-center trials across North America and Europe. Headquartered in New York, Relmada Therapeutics was incorporated in Delaware and maintains its research operations in the United States. The company is led by a management team with extensive experience in biopharmaceutical development, regulatory strategy and commercial planning. Relmada’s common stock is listed on the NASDAQ under the symbol RLMD.View Relmada Therapeutics ProfileRead more More Earnings Resources from MarketBeat Earnings Tools Today's Earnings Tomorrow's Earnings Next Week's Earnings Upcoming Earnings Calls Earnings Newsletter Earnings Call Transcripts Earnings Beats & Misses Corporate Guidance Earnings Screener Latest Articles Palantir Drops After a Blowout Q1—What Investors Should KnowShopify’s Valuation Crisis Creates Opportunity in 2026onsemi Stock Dips After Earnings: Why the Dip Is BuyableTSLA: 3 Reasons the Stock Could Hit $400 in MayNebius Breaks Out to All-Time Highs—Here's What's Driving It.3 Reasons Analysts Love DexComMonolithic Power Systems: AI Stock Beat, Raised and Upgraded Post-Earnings Upcoming Earnings AppLovin (5/6/2026)ARM (5/6/2026)DoorDash (5/6/2026)Fortinet (5/6/2026)Marriott International (5/6/2026)Warner Bros. 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PresentationSkip to Participants Operator00:00:02Good afternoon, ladies and gentlemen, and welcome to the Relmada Therapeutics Inc. first quarter 2024 financial results conference call. At this time, all lines are in listen-only mode. Following the presentation, we'll conduct a question-and-answer session. If at any time during this call you require immediate assistance, please press star zero for the operator. This call is being recorded on Wednesday, May 8th, 2024. I would now like to turn the conference over to Tim McCarthy, LifeSci Advisors. Please go ahead. Tim McCarthyManaging Director and Relationship Manager at LifeSci Advisors00:00:38Thank you, Colin, and thank you all for joining us this afternoon. With me on today's call are Chief Executive Officer Sergio Traversa and Chief Financial Officer Maged Shenouda. This afternoon, Relmada issued a press release providing a business update announcing financial results for the three months ended March 31st, 2024. Please note that certain information discussed on the call today is covered under the Safe Harbors provision of the Private Securities Litigation Reform Act. We caution listeners that during this call, Relmada's management team will be making forward-looking statements. Actual results could differ materially from those stated or implied by these forward-looking statements due to risks and uncertainties associated with the company's business. Tim McCarthyManaging Director and Relationship Manager at LifeSci Advisors00:01:15These forward-looking statements are qualified by the cautionary statements contained in Relmada's press release issued today and the company's SEC filings, including in the annual report on Form 10-K for the year ended December 31st, 2023, and subsequent filings. This conference call also contains time-sensitive information that is accurate only as of the date of this live broadcast, May 8th, 2024. Relmada undertakes no obligation to revise or update any forward-looking statements to reflect events or circumstances after the date of this conference call. Now I would like to turn the call over to Sergio. Sergio? Sergio TraversaCEO at Relmada Therapeutics00:01:53Thank you, Tim, as always, and good afternoon to everyone, and welcome to the Relmada first quarter 2024 conference call. We continue to achieve meaningful progress in the advancement of our ongoing phase 3 program for REL-1017 in Major Depressive Disorder, MDD, as well as in the promising preclinical novel psilocybin program, all of which I will briefly cover today. Following this, Maged will review our first quarter 2024 financial results, and then we will take your questions. Let's begin with an update on the late-stage phase 3 program for REL-1017. As a reminder, Relmada is focused on developing REL-1017 as an adjunctive treatment for MDD. We previously executed important revisions to Reliance II, the ongoing Study 302, which is a phase 3, two-arm, placebo-controlled pivotal study evaluating REL-1017 25 milligrams for adjunctive MDD. These modifications were aimed at controlling placebo response and improving the profile of patients enrolled. Sergio TraversaCEO at Relmada Therapeutics00:03:07The amended Study 302 protocol has been implemented across all of our clinical sites. Enrollment continues to advance, and our ability to leverage our close relationship with the study sites continues to play a critical role. Moreover, the ongoing initiative we put in place to drive trial awareness with prospective patients is also generating positive results. As we said on our last call, we are evaluating the quality and productivity of sites on a real-time basis and making tweaks as appropriate. As a reminder, we plan to enroll approximately 300 patients into Reliance II. Based on our current projection, we continue to expect Reliance II to be completed with top-line data anticipated in the second half of this year. We are also continuing to enroll those patients in our second phase 3 trial for REL-1017, Relight, or Study 304 that also has a planned enrollment of approximately 300 patients. Sergio TraversaCEO at Relmada Therapeutics00:04:11Like Reliance II, Relight is a randomized, double-blind, placebo-controlled four-week trial evaluating the efficacy and safety of REL-1017 as an adjunctive treatment of MDD in patients experiencing inadequate response to ongoing background antidepressant treatment. The primary endpoint of both studies is the same: the change in the MADRS total score from baseline to day 28 for REL-1017 as compared to placebo. I would like to emphasize again that we have made meaningful revisions to our screening and enrollment processes in order to ensure that we have patients that meet all of the qualifying criteria within our desired patient profile. To this end, we are now executing on a comprehensive adjudication process through which we require medical and pharmacy records for all patients enrolled in Reliance II and Relight. Sergio TraversaCEO at Relmada Therapeutics00:05:12Given this, the screen failure rate in this study has increased to approximately 80% versus approximately 50% in Reliance I and Reliance III, our previously completed phase 3 trials of REL-1017. However, we are highly confident that these changes will substantially enhance the probability of success of the current studies. I would also like to highlight that we have completed all of the necessary preclinical manufacturing and phase 1 studies required for a potential REL-1017 NDA filing, and our current focus is on executing the remaining 2 phase 3 studies, 302 and 304. Moving on now to the promising novel modified release psilocybin program. Sergio TraversaCEO at Relmada Therapeutics00:06:07We continue to anticipate the initiation of a single-ascending dose phase 1 trial in obese patients in the first half of this year to define the pharmacokinetic safety and tolerability profile of our modified release psilocybin formulation in this population, followed by a phase 2A trial to establish clinical proof of concept. Data from the planned 2A study is anticipated in the first half of 2025. These planned studies will build on the compelling preclinical data that were presented in a poster presentation at last November's AASLD meeting, the liver conference. These results showed the beneficial effect of low chronic dose psilocybin on multiple metabolic parameters in a rodent model of metabolic dysfunction-associated steatotic liver disease, or MASLD. Based on this data, low-dose psilocybin could improve lipids and glucose with potential for fewer side effects over other investigative treatment approaches such as GLP-1 glucagon and GIP. Sergio TraversaCEO at Relmada Therapeutics00:07:22So to summarize our multiple upcoming key milestones over the next 12-18 months, we anticipate the ongoing Reliance II study to be completed with top-line data in the second half of this year. In addition, we anticipate initiating a phase 1 clinical trial for our modified release formulation with psilocybin before the end of the current quarter. Lastly, while Maged will provide a detailed review of our financials, I would like to highlight that we continue to advance our pipeline for a position of significant financial strength with cash on hand to take us comfortably into 2025. I will now turn the call over to Maged to review our first quarter financial results. Maged? Analyst at Leerink Partners00:08:09Thank you, Sergio. Today, we issued a press release announcing our business and financial results for the three months ending March 31, 2024, which I will now review. For the first quarter ending March 31, 2024, total research and development expense was approximately $13.3 million as compared to $15.9 million for the comparable period of 2023, a decrease of approximately $2.6 million. The decrease was primarily associated with the completion of the long-term open-label study, Study 310, in the third quarter of 2023, as well as Reliance I and III. The non-cash charge related to stock-based compensation for R&D totaled $1.7 million in the most recently completed first quarter. Total general and administrative expense for the first quarter ending March 31, 2024, was approximately $9.7 million as compared to $12.3 million for the comparable period of 2022, a decrease of approximately $2.6 million. Analyst at Leerink Partners00:09:18The decrease was primarily driven by a decrease in stock-based compensation expense. The non-cash charge related to stock-based compensation for GAAP totaled $6.6 million in the most recently completed first quarter. For the first quarter ending March 31, 2024, the net loss was $21.8 million or $0.72 per basic and diluted share compared with a net loss of $26.3 million or $0.87 per basic and diluted share in the comparable period of 2023. As of March 31, 2024, we have cash, cash equivalents, and short-term investments of approximately $83.6 million compared to $96.3 million as of December 31, 2023. Cash used in operations in the first quarter of 2023 was $13 million. Based on our clinical development plan, our current cash position provides us with comfortable runway into 2025. I will now ask the operator to please open up the call for questions. Operator? Operator00:10:29Thank you. Ladies and gentlemen, we'll now begin the question-and-answer session. If you'd like to ask a question, please press star, followed by one. If you'd like to withdraw your question, please press star, followed by two. If you're using a handset, please lift the handset before pressing any keys. Your first question comes from Mark Goodman from Leerink Partners. Mark, please go ahead. Analyst at Leerink Partners00:10:55Hi, this is Basma for Mark. I had a question about the Reliance and Relight trials, the ongoing Reliance and Relight trials. You actually mentioned something that you were monitoring the trials, monitoring the looking at the blinded data before in the previous call, in the fourth Q earnings call. Can you provide some color about those kind of blinded data from what you see right now from the Reliance and Relight if you compare to the prior trial that had larger placebo response? Do you see any similarities? Do you see any difference? Just to give us some color about the strategy that you implemented to reduce the placebo response. Thank you. Sergio TraversaCEO at Relmada Therapeutics00:11:45Yeah, sure. And thanks for the question. I'll give you the top-down answer, and then we have Dr. Andrew Cutler. He's our clinical advisor on the call. We'll provide a little bit more details about this aspect. Well, first, let me say something about the blinded data, right? There is absolutely no way to guess from the blinded data the outcome of a clinical trial. And we experienced that in the last 2 trials that we had. So the help that we can get or everybody can get from monitoring the blinded data is only and exclusively to see if there is something that it's not that doesn't make—I can't find the right word, but that is not consistent, right? Sergio TraversaCEO at Relmada Therapeutics00:12:40For a given example, if there are individual patients with the MADRS scores week over week that goes up and down, or we call it zigzag, then you know that there is something that is not right. It can be the patient or it can be the site. But usually, a patient that responds is consistent over four weeks, and if it doesn't respond, it's still consistent over the four weeks. So if you see a zigzag, that's a signal that something is not consistent. And so we take a look to that, to the patients, and mostly to the site. So that's really the only help that you can get from the blinded data. But it is important, right, to continue to monitor to see that not many of these patients with this zigzag pattern get into the trial. Sergio TraversaCEO at Relmada Therapeutics00:13:28When it's in, there is nothing we can do, but we can at least revise and advise the site that something is kind of like a red flag. And Andy, you are on the call. Would you mind to provide some more details about it? Andrew CutlerClinical Advisor at Relmada Therapeutics00:13:44Yes. I absolutely agree with what Sergio said. What you look for is consistency and quality indicators. In addition to what he said about the primary, the MADRS zigzagging, you also look for consistency across different scales. The key secondary outcome, of course, being a CGI, usually that moves in the same direction as the MADRS, which is measuring depression symptoms. So you look for that. I would say also that in the previous trial, sites were allowed to enroll rather quickly without watching the quality as closely as we're doing now. And that can certainly be a problem. So we're now really being much more careful with the enrollment, not allowing a site to over-enroll patients until we've looked at the quality, monitoring the quality of each site and the trial overall. And I would say things are looking fine from that point of view at this point. Sergio TraversaCEO at Relmada Therapeutics00:14:48Thank you, And. I hope that answered your question. Analyst at Leerink Partners00:14:53Thank you. Operator00:14:56Your next question comes from Andrea Tan from Goldman Sachs. Please go ahead. Analyst at Leerink Partners00:15:02Hi, Sergio. Thanks so much for taking the question. Maybe one follow-up to your remarks right there. As you are monitoring the sites, if you do see the inconsistencies that you've just spoken about, maybe walk us through what steps then you would take to remediate those issues. And then I have 1 follow-up question. Thank you. Sergio TraversaCEO at Relmada Therapeutics00:15:23Yes. Good afternoon, Andrea. Thanks for the question. As before, I will give you the short answer, and then Andy, if you would like to provide a little bit more details. In general, well, first, do you contact the site and you discuss any details regarding patients or patients that have some inconsistency? Then you go through the whole process. Ultimately, if that becomes a pattern, you don't want to have a site that shows inconsistency enrolling 10, 20 patients because that would affect the whole trial. The ultimate measure is to close the site. Andy, I'm sure I can give you a little bit more color on this. Andrew CutlerClinical Advisor at Relmada Therapeutics00:16:13Yeah, that is well said. The most important thing is to not allow a site to continue to enroll patients and have problems like that. And so, as you know, if 1 site has too many patients, 1 or 2 sites, that can kill a trial. But also, if you do see this well, first of all, the site also knows, having run sites, the site knows now if you're looking over my shoulder and you're going to call me, it really does make them be on their best behavior, if you will, and not cut corners. But ultimately, we have closed down some sites that had quality issues. So ultimately, what you do is you just stop them from enrolling so that they don't have a chance to hurt the study. Analyst at Leerink Partners00:16:59Okay. Sergio TraversaCEO at Relmada Therapeutics00:17:00Thank you, Andrea. Analyst at Leerink Partners00:17:01Andy, can you just remind us quickly, are you planning on having an interim analysis, or is there going to be any type of mechanism in place for the DMC to recommend stopping the study early as they have in your prior trial? Sergio TraversaCEO at Relmada Therapeutics00:17:17We will have not we, but the data monitoring committee will have a look at the data at some point, very close to the end. But this is not an interim analysis because there is no statistical penalty. It's a sample reestimation. They will let us know if the sample that we have in the trial is enough to reach statistically significant or if we have to expand the trial. There is no early stop planned. Analyst at Leerink Partners00:17:52The other major function of the DMC, of course, is to monitor safety. The good news is the safety and the tolerability have looked very good. Analyst at Leerink Partners00:18:04Great. Thanks so much. Sergio TraversaCEO at Relmada Therapeutics00:18:05Thanks, And Thank you, Andrea. Operator00:18:08Your next question comes from Andrew Tsai from Jefferies. Andrew, please go ahead. Analyst at Jefferies00:18:14Hey, congrats on the progress. This is Matt calling in for Andrew. And I guess continuing with the same theme, do you have any specifics on the numbers of sites that you've had to pause, close, or been able to even reopen using your monitoring, real-time analysis? And then also, we've seen. Sergio TraversaCEO at Relmada Therapeutics00:18:35Sorry. No, maybe it's me, but I can barely hear you. Analyst at Jefferies00:18:40Okay. Can you hear me better now? Sergio TraversaCEO at Relmada Therapeutics00:18:43Oh, much better. Yeah. Thank you. Sorry for that. Analyst at Jefferies00:18:46Okay. Yeah, no problem. So yeah, I was just asking, continuing with the real-time site analysis, if you'd had any specifics on the number of sites that you've had to pause, close, or maybe even reopen? And then also, over the past year, we've seen quite a few companies that have announced delays, for instance, schizophrenia and epilepsy spaces. And are you seeing any increased level of competition in terms of funding the right MDD depression patients? And then I. Sergio TraversaCEO at Relmada Therapeutics00:19:15Well, thanks for the question. Yeah. Thank you very much for the question. So in terms of sites, right, the site selection is not like a fix that you decide 50, 60 sites at the beginning, and you finish with the same sites. It is an ongoing process. So constantly, there is a revision of sites. And some site is closed not only for quality issue, also for the competing studies or they exhausted the patient population that they can enroll into the site. So it is an ongoing. I don't have on the top of my mind a really specific number, but it's not like that at some point you do a review. It's an ongoing process. So maybe Andy, when I finish, the other answer can give you a little bit more details because he runs clinical sites. So he is more into the detail of the process. Sergio TraversaCEO at Relmada Therapeutics00:20:23The second question, would you mind to repeat it? Analyst at Jefferies00:20:27Yeah. Just the competing study. Sergio TraversaCEO at Relmada Therapeutics00:20:29The competing study, right? Analyst at Leerink Partners00:20:30Yeah, exactly. Sergio TraversaCEO at Relmada Therapeutics00:20:31Yeah. Well, there is clearly some competition out there. And mostly, I mean, usually, a site cannot or does not take on 3, 4 studies that enroll the same kind of patients. In our case, it's a little bit particular because we are doing the studies are for adjunctive treatment of depression. So that's the competition. It's much less because there are not many other programs, especially in phase 3, that enroll patients in adjunctive. We do believe there was 1 other company that finished 1sizable, big study a few weeks ago. But I do believe that the majority of their sites were outside the U.S. So there was relative competition. It was not an antidepressant anyway. We keep on hearing that the psilocybin, there are a lot of trials ongoing with psilocybin in depression. Sergio TraversaCEO at Relmada Therapeutics00:21:44That is not really a direct competitor, but still, it keeps the sites busy and is high-dose psilocybin for PTSD and MDD. So yeah, to summarize, yes, there is competition, but we are in a specific indication where the competition is much lower. Andy, would you mind to provide a little bit more color? Andrew CutlerClinical Advisor at Relmada Therapeutics00:22:12Yes. I'll answer the 2nd one first. And that is that Sergio is exactly right. At the site level, you don't want to take too many competing studies. Usually, though, the study criteria are different enough that you can do, say, two or three depression studies without significantly impairing because a patient will more clearly fit into 1 protocol than another. So as far as the first question, I don't have the exact number of sites that we've closed down offhand. But sites do close for various reasons. That's certainly true. But we have stopped enrollment at a couple of sites. I can say that. But it's not a lot, fortunately. And I think some of it is simply the process of overseeing the sites. Now, the sites know that they're being watched. They know that we're monitoring quality. Andrew CutlerClinical Advisor at Relmada Therapeutics00:23:00That often changes the behavior enough so that significant corrective action isn't necessary. Analyst at Jefferies00:23:07Got it. Yeah. That makes sense. And then I guess regarding the phase 1 Psilocybin program that you're going to be kicking off soon, can you describe the study design and what positive data would entail? Sergio TraversaCEO at Relmada Therapeutics00:23:22Yes. It's very simple. We'll start with a Phase 1, a single dose, the starting dose of Psilocybin modified release. So the interesting part is the patient population. Or technically, Phase 1, you do it in a healthy volunteer. But it's well known that Psilocybin is a relatively safe product at high dose, and we are using a dose very, very much, much lower, like 1/20th or 1/30th of the dose that is used as a psychedelic for the treatment of psychiatric diseases. So on the safety side, we feel extremely comfortable. But the indication that we'll pursue for Psilocybin is into the metabolic space, so obesity and glucose and fatty liver. So the data that we are looking for is mostly PK data in obese patients. Sergio TraversaCEO at Relmada Therapeutics00:24:25The particular is the patient population that will be obese healthy volunteers, and which we should start over the next month or 2. We said within the first half. So we are getting there. It's a short study. So the whole study will last like 3-4 months maximum. Analyst at Jefferies00:24:49Excellent. Thank you. Sergio TraversaCEO at Relmada Therapeutics00:24:51Thank you. Operator00:24:53Ladies and gentlemen, as a reminder, if you'd like to ask a question, please press star, followed by 1. Your next question comes from Louir from Mizuho. Please go ahead. Analyst at Mizuho Securities00:25:06Hi. This is Charles for Louir. I had a question about kind of the screening failure rate and if you think that's going to kind of stay at 80% throughout the study enrollment. And then also, if you could clarify if Reliance II screening failure rate was also 50% before the new protocol. Thank you. Sergio TraversaCEO at Relmada Therapeutics00:25:29Hey, Charlie. Thanks for the question. And so yeah, the screening failure, it's high, but we look at the reason for the screening failure. And there are legitimate reasons, right? Usually, it's drug-drug interaction or concomitant mostly it's concomitant medication. So yeah, these are legitimate reasons not to enroll in the study. And most of the screening failure actually come from the site. And with that said, we are in constant review, and we listen very carefully to the feedback from the sites. And there is anything that we can do to increase the enrollment rate or decrease the screening failure, but without decreasing the quality and increasing the risk of the trial, we have been doing that. So there are certain things that have been, especially on the drug-drug interaction or concomitant medication more than interaction, that have been changing over time. So that should facilitate. Sergio TraversaCEO at Relmada Therapeutics00:26:41This is a back and forth from the company and the site. So yeah, they give us the feedback, and we see patients with that characteristic that it could fit into the trial, but we cannot put it in because of the inclusion and exclusion. So we revised. And in a dialogue with the FDA, of course, we have made a few detailed revisions of the protocol over time. So we don't know what we'll do to the screening failure, but definitely, there is a chance that we could get a little better. And the second question was at the beginning. Yeah, that's a great question, but I don't have the answer on the top of my head. And the screening failure at the beginning of 3 or 2, probably there are not a lot of patients enrolled. So I don't know how much that number is meaningful. Sergio TraversaCEO at Relmada Therapeutics00:27:35But maybe Andy or Maged, if they have some more color on that, the screening failure on the Study 302 before we amended the protocol. Andrew CutlerClinical Advisor at Relmada Therapeutics00:27:47I don't believe it was quite the yeah. Go ahead, Maged. Sorry. Analyst at Leerink Partners00:27:51Go ahead, Andy. Yeah, it was certainly not quite as high. I don't want to put a number out there without confirming with our internal team. So we'll have to get back to you, so. Andrew CutlerClinical Advisor at Relmada Therapeutics00:28:03Yep. Exactly. But I would not be put off by screening failure. We're trying to find the right patients, and that's critically important. Patient selection is absolutely a source of failure in studies. Sergio TraversaCEO at Relmada Therapeutics00:28:18Okay. Thanks,. Sergio TraversaCEO at Relmada Therapeutics00:28:21Right. And sorry. Yeah. As we mentioned in some of our calls, right, 1 of the biggest changes, the amendment we made to the protocol is that there is now a requirement for medical and pharmacy records. And that's by itself increased the screening failure. But also, at the same time, you are relatively comfortable that that patient comes from a doctor that has diagnosed and prescribed medication and that the patient actually purchased the medication from the pharmacy. So the 2 things, they go together, high screening failure, but there is clearly an improvement in the risk profile of the patients enrolled. I hope that answers your question. Analyst at Mizuho Securities00:29:10Yeah. Thank you. Operator00:29:14There are no further questions at this time. I'll turn it back to Sergio for closing remarks. Sergio TraversaCEO at Relmada Therapeutics00:29:23Thank you. In summary, we continue to firmly believe that we have an approvable drug in REL-1017, and we are excited by the potential of our novel Psilocybin derivative program. We look forward to reporting on further progress with our pipeline throughout the remainder of 2024. I do remain grateful to the Relmada team for their continued hard work and dedication to executing on our mission. Also, as always, I would like to extend my sincere thanks to the patients and clinical partners involved in the REL-1017 trials for their participation in the advancement of this promising investigation on medicine through development. Thanks a lot to everyone for the attention and the interest, and looking forward to the next conference call. Operator00:30:15Ladies and gentlemen, this concludes your conference call for today. We thank you for participating and ask that you please disconnect your lines.Read moreParticipantsExecutivesAndrew CutlerClinical AdvisorSergio TraversaCEOAnalystsTim McCarthyManaging Director and Relationship Manager at LifeSci AdvisorsAnalyst at JefferiesAnalyst at Leerink PartnersAnalyst at Mizuho SecuritiesPowered by