MediWound Q1 2025 Earnings Report

MediWound EPS Results

• Actual EPS: -$0.07
• Consensus EPS: -$0.65
• Beat/Miss: Beat by +$0.58
• One Year Ago EPS: -$1.05

MediWound Revenue Results

• Actual Revenue: $3.96 million
• Expected Revenue: $5.20 million
• Beat/Miss: Missed by -$1.24 million
• YoY Revenue Growth: N/A

MediWound Announcement Details

• Quarter: Q1 2025
• Date: 5/21/2025
• Time: Before Market Opens
• Conference Call Date: Wednesday, May 21, 2025
• Conference Call Time: 8:30AM ET

MediWound (NASDAQ:MDWD) (NASDAQ: MDWD) is a biopharmaceutical company headquartered in Yavne, Israel, specializing in the development and commercialization of innovative enzymatic therapies for burn and wound management. Since its establishment, the company has focused on advancing proteolytic enzyme technology to address critical needs in debridement and tissue repair. MediWound operates research and development facilities in Israel and maintains commercial offices in the United States to support its global market presence.

The company’s lead product, NexoBrid®, is an enzyme-based debriding agent designed to selectively remove burn eschar without harming viable tissue. NexoBrid has received regulatory approval in the European Union and by the U.S. Food and Drug Administration for use in adults with severe thermal burns. MediWound is also advancing EscharEx™, a topical therapy aimed at debriding chronic and hard-to-heal wounds, currently undergoing pivotal clinical trials to expand its therapeutic portfolio.

MediWound’s commercial reach spans North America, Europe and other international markets through a network of strategic distribution partners. In the United States, the company supports its sales efforts with a dedicated subsidiary and field-based clinical specialists, while in Europe it works with established distributors to ensure product availability and regulatory compliance. The company continues to explore additional indications and territories to broaden access to its enzymatic treatments.

Leadership at MediWound is spearheaded by Chief Executive Officer Dan Rosenwasser, who has guided the company’s strategic expansion and commercialization initiatives. Under his direction, MediWound has strengthened its manufacturing capabilities and fortified its clinical pipeline. The management team’s combined expertise in biotechnology, regulatory affairs and commercial operations underpins the company’s mission to deliver advanced wound care solutions to patients worldwide.

MediWound Q1 2025 Earnings Call Transcript

Key Takeaways

• EscharEx Phase III VALUE trial is on track with 216 patients enrolled across ~40 U.S. and European sites, targeting an interim analysis at 65% enrollment in mid-2026.
• Strategic collaborations now include nearly all major wound care companies—most recently Keresys for the diabetic foot ulcer program—and MediWound secured a €2.5 million EIC grant to support DFU clinical advancement.
• A randomized 45-patient Phase II head-to-head study versus collagenase is planned for H2 2025 to generate comparative data crucial for market access and pricing.
• NexoBrid demand surged with a 207% YOY increase in U.S. revenue and 31% sequential growth; manufacturing capacity is being expanded with a new Israel facility operational by year-end 2025 and U.S. backup plans supported by BARDA.
• Q1 revenue was $4 million (vs. $5 million prior year) driven by lower BARDA-funded services, operating loss widened to $5.2 million, net loss improved to $0.7 million, and cash totaled $38.7 million at quarter-end.

Presentation

[Operator]

Good day, and welcome to the MediWound First Quarter 2025 earnings call. All participants will be in listen-only mode. Should you need assistance, please signal a conference specialist by pressing the star key followed by zero. After today's presentation, there will be an opportunity to ask questions. To ask a question, you may press star, then one, on a touch-tone phone. To withdraw your question, please press star and then two. Please note this event is being recorded. I would now like to turn the conference over to Dan Ferry of LifeSci Advisors. Please go ahead.

[Dan Ferry, Managing Director at LifeSci Advisors]

Thank you, Operator, and welcome everyone. Earlier today, pre-market open, MediWound issued a press release announcing financial results for the first quarter ended March 31, 2025. You may access this press release on the company's website under the Investors tab. I would ask you to review the full text of our forward-looking statements within this morning's press release. Before we begin, I would like to remind everyone that statements made during this call, including the Q&A session relating to MediWound's expected future performance, future business prospects, or future events or plans, are forward-looking statements as defined under the Private Securities Litigation Reform Act of 1995. These statements may involve risks and uncertainties that could cause actual results to differ materially from expectations and are described more fully in our filings with the SEC.

[Dan Ferry, Managing Director at LifeSci Advisors]

In addition, all forward-looking statements represent our views only as of today, and MediWound assumes no obligation to update or supplement any forward-looking statements, whether a result of new information, future events, or otherwise. This conference call is the property of MediWound, and any recording or rebroadcast is expressly prohibited without the written consent of MediWound. With us today are Ofer Gonen, Chief Executive Officer of MediWound, and Hani Luxenberg, Chief Financial Officer. Barry Wolfenson, EVP of Strategy and Corporate Development, is also participating in today's call. Following our prepared remarks, we will open the call for Q&A. Now, I would like to turn the call over to Ofer Gonen, Chief Executive Officer of MediWound. Ofer?

[Ofer Gonen, CEO at MediWound]

Hey, thank you, Dan, and good morning, everyone. We entered 2025 with strong execution across our clinical, commercial, and operational priorities, maintaining the momentum we established in 2024. The value-based restudy or SCRX is on track, and the addition of a collaboration with Kerecis marked a significant milestone, actually bringing nearly all the major wound care companies into our clinical research program. Meanwhile, NexoBrid continues to gain global traction as we advance long-term manufacturing investments to support sustained growth. Let's begin with SCRX, our next-generation enzymatic debridement therapy for chronic wounds. Recruitment for the value-based restudy for venous leg ulcers is progressing as planned. The global trial will enroll 216 patients across approximately 40 sites in the United States and Europe. Most of the U.S. sites are already open, and the majority of the European sites are expected to be activated in the third quarter of 2025.

[Ofer Gonen, CEO at MediWound]

Our SCRX program is strategically de-risked, building on the strong results of our phase ll studies. If SCRX simply replicates those clinical outcomes, the phase lll trial would be considered a clear success, with results expected to support both regulatory submissions and commercial positioning. The value-based protocol also includes key enhancements designed to further increase the likelihood of success. We have a larger patient population to increase statistical power. An interim analysis assesses 65% enrollment, enabling adaptive adjustments. This assessment is anticipated in mid-2026, and we have standardized treatment protocols to minimize variability and ensure consistency across sites. Finally, it is important to note that SCRX shares the same FDA-approved active pharmaceutical ingredient as NexoBrid for nearly identical indication, eschar removal.

[Ofer Gonen, CEO at MediWound]

To further strengthen our BLA submission and to enhance commercial readiness, we are planning a 45-patient randomized prospective phase two head-to-head comparison of SCRX versus collagenase, scheduled to begin in the second half of 2025. This study will include both Santyl and the European collagenase product Iruksol, generating critical comparative data that will be instrumental in supporting our market access and pricing strategies. This quarter also marks a major milestone in our strategic research collaborations. We now have participation by almost all the leading global wound care companies across our clinical development programs. Added to the list is Kerecis, which will support our upcoming diabetic foot ulcer trial by providing its tissue product, MariGen. It is a fish skin graft for active closure. With Solventum, Molnlycke, Kerecis, MiMedx supporting our clinical programs, SCRX has received strong external validation from most of the key players in the industry.

[Ofer Gonen, CEO at MediWound]

The growing excitement around EscharEx comes from its clear clinical advantages, particularly when we compare it to Santyl, the only FDA-approved enzymatic debridement agent. This was further reinforced by recent peer-reviewed publications in wounds, which included a post-hoc analysis of our phase II chronic study in VLUs. The data there confirmed EscharEx's superiority across multiple endpoints, including faster debridement, enhanced granulation tissue formation, and improved wound closure. The company has secured the EUR 2.5 million grant component of the European Innovation Council Accelerator funding to support the clinical and regulatory advancements of EscharEx for the treatment of diabetic foot ulcers. Following a successful evaluation process, the company engaged in discussions for the EUR 13.75 million equity investment, which may not be materialized. We don't expect this to impact our timeline. The DFU study remains on track to begin in 2026, pending alignment with both the FDA and EMA on the trial protocol.

[Ofer Gonen, CEO at MediWound]

The rationale for our excitement around the DFU program was clearly demonstrated at recent major international wound care conferences, including the WHS, SAWC, and Yuma. We presented DFU-specific data from our first phase II study of SCRX. That study included patients with DFU, VLU, and with trauma wounds, and the DFU results mirrored the strong efficacy we have already seen in VLUs. I will mention a few key findings. SCRX achieved 58% complete debridement compared to just 14% with a gel vehicle. Granulation tissue was observed in 42% of SCRX-treated wounds versus only 11% with a vehicle. The median time to complete debridement was just 23 days for SCRX compared to 128 days with a gel, and the median time to wound bed preparation was 24 days for SCRX, whereas it was not achieved at all in the vehicle group.

[Ofer Gonen, CEO at MediWound]

With all this momentum and assuming positive results from the value-based restudy, we believe SCRX is well-positioned to become the global leader in enzymatic wound debridement. Now, let's turn our attention to NexoBrid, our innovative enzymatic therapy for severe burns. U.S. adoption of NexoBrid continues to expand with consistent ordering from nearly 60 burn centers. Our commercial partner, Vericel, reported a 207% year-over-year increase and a 31% sequential increase in NexoBrid revenue during the first quarter of 2025. In Japan and Europe, demand continues to exceed manufacturing capacity. We remain on track with the commissioning of our new manufacturing facility, with operational readiness expected by year-end 2025. Commercial availability will follow regulatory approvals from the FDA and EMA, and it is anticipated in 2026. This facility will significantly expand our production capabilities, enabling us to meet growing global demand and support sustained revenue growth.

[Ofer Gonen, CEO at MediWound]

NexoBrid also featured prominently in recent scientific and clinical communications. Results from a pediatric phase III study were published in the peer-reviewed journal Burns, reinforcing NexoBrid's efficacy and safety as a non-surgical eschar removal therapy for both adults and pediatric burn patients. At the American Burn Association annual meeting, new data were presented on NexoBrid's emergency use during the Israel-Hamas war. NexoBrid was used to treat patients with blast injuries and complex burns. One hospital reported treating a trauma or a burn patient every minute for 24 hours, highlighting NexoBrid's vital role in mass casualty and emergency situations. Governments around the world took note of NexoBrid's impact. In particular, the U.S. government has expressed interest in establishing a domestic backup manufacturing site. In response, we have initiated planning and site selection for a future U.S.-based facility, a project supported by BARDA.

[Ofer Gonen, CEO at MediWound]

We are also seeing increased interest in stockpiling NexoBrid as part of global emergency preparedness efforts, and we believe some of these discussions will translate into concrete opportunities once our manufacturing capacity expands. I would like to turn the call over to Hani to review our financial performance in more detail. Hani?

[Hani Luxenburg, CFO at MediWound]

Thank you, Ofer, and good morning. Total revenue for the first quarter of 2025 was $4 million compared to $5 million in the first quarter of 2024. The decline reflects lower revenue from BARDA-funded development services as the NexoBrid development program for both adult and pediatric population approaches completion. Gross profit for the quarter was $0.7 million, representing a gross margin of 19% compared to $0.6 million and a gross margin of 12% in the prior year period. This improvement reflects a favorable change in our revenue mix. R&D expenses totaled $2.9 million compared to $1.5 million in Q1 2024, reflecting continued investment in the SCRX value-based trial and associated development activities. SG&A expenses were $3.1 million compared to $2.9 million in the prior year period. Operating loss for the quarter was $5.2 million versus $3.7 million in Q1 2024.

[Hani Luxenburg, CFO at MediWound]

Net loss was $0.7 million or $0.07 per share compared to a net loss of $9.7 million or $1.05 per share last year. The improvement was primarily driven by non-cash financial income related to warrant revaluation. Adjusted EBITDA loss for the quarter was $4 million compared to $2.9 million in the prior year period. Now, turning to our balance sheet. As of March 31, 2025, we had $38.7 million in cash, cash equivalents, and deposits compared to $43.6 million at year-end 2024. We used $5.1 million to fund our operations during the quarter. That concludes my financial review, Ofer. Back to you.

[Ofer Gonen, CEO at MediWound]

Thank you, Hani. In summary, we began 2025 with strong execution and meaningful progress across our key programs. The value-based trial of SCRX remains on track, supported by growing scientific evidence and engagement of virtually all major wound care players and wound care partners. We are advancing complementary studies to support market access and future commercial success. NexoBrid continues to gain traction globally with record US sales, high demand in international markets, and new clinical data demonstrating its value in both routine and emergency care. Operationally, we remain focused on scaling our manufacturing capabilities to support long-term growth, with the new manufacturing facility progressing on schedule and the US expansion plans underway. With a solid foundation, a focused pipeline, and strong strategic alliances, we are well-positioned to deliver long-term value. With that, I will now turn back the call to the operator to open the line for questions. Operator?

[Operator]

We will now begin the question-and-answer session. To ask a question, you may press Star, then 1 on your touch-tone phone. If you are using a speakerphone, please pick up your handset before pressing the keys. If at any time your question has been addressed and you would like to withdraw your question, please press Star and then 2. Our first question comes from Chase Knickerbocker with Craig-Hallum. Please go ahead.

[Chase Knickerbocker, Analyst at Craig-Hallum Capital Group]

Good morning and good afternoon. Appreciate you taking the questions. Maybe just first on manufacturing, can you remind us what is kind of yet to be done to kind of be ready for scale-up by year-end? Any additional feedback that you've gotten from the relevant agencies around timing of those required regulatory approvals, sign-offs, particularly with the FDA? Thanks.

[Ofer Gonen, CEO at MediWound]

Hi, Chase. Great to have you with us today. Let me address the manufacturing question. As I said, the demand for NexoBrid is increasing due to several factors. We have major market launches, US-Japan, growing governmental interest, expanding of indications, the pediatric indication, the military use. We are focusing on making sure that we will be able to deliver. We completed the construction of the new facility, and we are now in the commissioning phase. Actually, we are on time, and we anticipate achieving all operational capacity by the end of 2025. After that, we are calling for inspections, EMA and FDA. EMA is easier because the inspectors are Israelis, so we expect it to be quite sooner. As for the FDA, there is quite often uncertainty about how they are doing remote inspections these days. Anyway, we are expecting that only around mid-2026, so we have time.

[Chase Knickerbocker, Analyst at Craig-Hallum Capital Group]

Got it. And then just on the potential for some U.S. capacity, any thoughts on kind of when investors should be expecting kind of movement there, when we could have seen kind of a site be identified, something formal with the U.S. government in place, etc.? Do you have any thoughts on kind of timing there?

[Ofer Gonen, CEO at MediWound]

Yeah. As you know, the U.S. government has expressed interest in establishing such a domestic backup manufacturing site. We have a project that we believe will be finished by Q3 this year. After that, we will have better understanding about the location, timing, etc. As I said, this project is fully supported by BARDA.

[Chase Knickerbocker, Analyst at Craig-Hallum Capital Group]

You had a number of posters and presentations at SAWC, and I would imagine you had an opportunity to catch up with a lot of the relevant clinicians at a lot of your sites for the VLU study. Any incremental thoughts from them? As far as enrollment goes, are things kind of to plan as far as what you expected thus far? Anything taking longer or shorter than expected? Just kind of an update on kind of initial cadence of activations and as we look for some initial enrollment progress here in the short-term?

[Ofer Gonen, CEO at MediWound]

Yeah. Since I met you at this conference, I know that you have been there. In this conference, MediWound had a very strong performance. Many, many presentations, posters, abstracts were shared. We met the majority of the PIs from the United States, and the excitement is there. This trial is the most significant and comprehensive trial in venous leg ulcer patients in the past few decades. This is why all the leading wound care companies and the top KOLs are collaborating with us in this endeavor because they know that if it is a success, this trial is going to have a huge impact on the market. As we said, the recruitment of this study is progressing as planned. We expect the next milestone, the most important milestone, is having the interim data mid-2026, and we do not see an issue in getting there.

[Chase Knickerbocker, Analyst at Craig-Hallum Capital Group]

Thanks, Ofer.

[Ofer Gonen, CEO at MediWound]

Thank you.

[Operator]

The next question comes from RK with H.C. Wainwright. Please go ahead.

[Ramakanth Swayampakula, Managing Director at H.C. Wainwright & Co]

Good afternoon, Ofer and Hani. A couple of quick questions. In your prepared remarks, you started talking a little bit about stockpiling of NexoBrid. In general terms, how are you planning for this? I know you have enough demands on you for the product. I am just trying to think in general terms, what could we even be thinking in dollar amounts worth of stockpiling that you could be expected to fill?

[Ofer Gonen, CEO at MediWound]

Hi, RK. This is great to have you on the line today. It's a great question. Currently, we have guidance regarding our revenue. Okay? We can achieve those numbers, and currently, our preference is to treat patients, not to use NexoBrid. I don't want it to be in a shelf somewhere. Even governments that we are speaking with, they are familiar with our priority, first of all, to treat real patients, and it will also support great commercial launches in specific territories. As for how much governments will buy in 2026, 2027, I can't really give you the numbers. All I can say is everything is embedded in the guidance that we are giving, generating revenue of $24 million this year and generating $30-$33 million next year. After that, we will know better.

[Ofer Gonen, CEO at MediWound]

I can just share with you that after what countries saw, what NexoBrid did during the Israeli-Hamas war, there is a growing interest around many governments, United States, Europe, and others, and we are just starting the discussions now.

[Ramakanth Swayampakula, Managing Director at H.C. Wainwright & Co]

Thank you for that. In terms of the SCRX and the ongoing SCRX phase lll trial, you were saying you have 40 centers running the trial for you. Of the 40 centers, what % is in the U.S.? Would there be any reason why the study could get completed ahead of time than what you are anticipating right now?

[Ofer Gonen, CEO at MediWound]

It's an interesting question. First of all, as for the facts, the sites, almost 50% of the sites, between 17-20, will be in the United States. We have two to three sites in Israel, and the rest will be in Europe. This is the structure of the sites. As for enrollment pace, as you can imagine, there are 1.5 million patients in the United States that are relevant to such a treatment. We chose the most performing sites to participate in the trial. We don't think that enrollment will be an issue. Having said that, we spend a lot of energies, a lot of money, and a lot of efforts making sure that we are recruiting the right patients. I don't want a healthy patient to join the study. I don't want someone that a placebo can cure his wound to join the study.

[Ofer Gonen, CEO at MediWound]

I don't want a person that by mistake, by chance, know the PI to join the study. The screening process is something which is very, very articulated. We plan half a patient per site per month. This is our track record of clinical trials in this indication. This is what we know from the previous clinical trials that our CRO, this is the track record that they have. We don't see a reason that it will be quicker. Actually, we are not in a rush. The only thing that we care about is that this trial will be a success and that it will change the treatment of chronic wounds.

[Ramakanth Swayampakula, Managing Director at H.C. Wainwright & Co]

Last question from me, Ofer. In terms of the phase 2 head-to-head study against collagenase, which you plan to start soon, would the results of that study and the phase lll study come around the same time, or the phase ll would come ahead of it? Just trying to understand so that when the whole package will be ready to be sent off to the regulators.

[Ofer Gonen, CEO at MediWound]

The plan is that the trials will finish. I think the head-to-head study, since it did not start yet, so I cannot tell for sure, but the plan is that it will be finished ahead of the phase lll study. It is a much shorter study. We are looking, there are all kinds of parameters that will impact, especially safety, market aspects, pricing aspects, etc. We do not need the long follow-up, the three-month follow-up after the study completes in the phase lll trial. This is much shorter and more simple trial. As far as we are planning now, we will get the final results before the phase lll is completed.

[Ramakanth Swayampakula, Managing Director at H.C. Wainwright & Co]

Thank you. Thank you very much for taking all my questions.

[Ofer Gonen, CEO at MediWound]

Thank you, RK.

[Operator]

The next question comes from Michael Okunewitch with Maxim Group. Please go ahead.

[Michael Okunewitch, Analyst at Maxim Group]

Hey there. Thank you so much for taking my questions today.

[Ofer Gonen, CEO at MediWound]

Thanks, Michael.

[Michael Okunewitch, Analyst at Maxim Group]

I guess I'd just like to follow up a little bit on the head-to-head study. In particular, if you could help us understand what kind of considerations might go into the pricing strategy. If you're achieving faster debridement than Santyl with fewer applications, do you then justify enhanced pricing to match cost per application? Do you also need to consider the reduced healthcare utilization with faster debridement as well? I'd just like to get a sense of what factors, the metrics, would be relevant for those pricing determinations.

[Ofer Gonen, CEO at MediWound]

Hi, Michael, and thank you for joining us today. Barry, can you please address that question?

[Barry Wolfenson, EVP of Strategy and Corporate Development at MediWound]

Sure. Absolutely. Hi, Michael. Good question. I think the model that we have out right now with our $851 price target is merely the first component that you mentioned, which is what was the cost of the product over the duration of the treatment period. And we're comparing the average cost of Santyl over a treatment period versus then what would be the anticipated premium for the average cost of SCRX. The next part is what we'll be doing. We're actually doing a full market research study on market access and pricing that will get into the second component, which is the HEOR, the health economics component of it, where we do look at what are all the downstream impacts of saving six weeks of treatment from the time that it takes to apply the drug, the nursing time, the physician time to what happens to these patients.

[Barry Wolfenson, EVP of Strategy and Corporate Development at MediWound]

Do some of them end up in the hospital? Do they have infections that are needed to be treated? Once we get all of that together, if indeed there is a good pot of dollars that the facility would save on average, we think that we have the opportunity to take a higher premium against Santyl.

[Michael Okunewitch, Analyst at Maxim Group]

All right. Thank you. I really appreciate that additional clarity. When thinking about the potential for new stockpiling programs for NexoBrid, would you expect that these would come from your expanded new manufacturing facility, or could there be more agreements similar to the US domestic program to set up a dedicated manufacturing for those?

[Ofer Gonen, CEO at MediWound]

It's a good question. We are planning to have some flexibilities here. We have the current manufacturing facility. We are going to have available the new scale-up manufacturing facility. We are planning a new manufacturing facility in the United States. We have another facility to support the Department of Defense program, another facility that will be completed by the end of 2025. Actually, it will be completed this year. For MediWound, those facilities significantly expand our manufacturing capacity. We do not want to be in the position three years from now launching SCRX, telling the analysts again, "Hey, there is huge demand, but we cannot support that." Those facilities significantly expand our manufacturing capacity and will provide us with critical support, first of all, to a successful launch of SCRX and to be able to satisfy the demands for all the countries that will be interested in stockpiling.

[Michael Okunewitch, Analyst at Maxim Group]

All right. There is an expectation that this new U.S. backup manufacturing could be used to help support demand commercially as well, not just stockpiling.

[Ofer Gonen, CEO at MediWound]

Yeah. The current facility that we are building in Israel is enough to support the demand we anticipate. Adding a facility in the United States can be not only backup, but also to expand manufacturing of NexoBrid and maybe to support us with the manufacturing of EscharEx as well.

[Michael Okunewitch, Analyst at Maxim Group]

All right. Congrats on all the great progress, and thank you for taking my questions once again.

[Ofer Gonen, CEO at MediWound]

Thank you.

[Operator]

The next question comes from Scott Henry with Alliance Global Partners. Please go ahead.

[Scott Henry, Managing Director and Senior Research Analyst at Alliance Global Partners]

Good day. First question. The NIH funding environment is certainly challenging, which could impact BARDA, Department of Defense. It seems like that revenue was down a little bit in Q1. Are you expecting that to rebound significantly in the coming quarters, or how should we think about that overhang, even though that's not a main priority? Obviously, product sales are more important. Just trying to get a sense of how to model that development services line.

[Ofer Gonen, CEO at MediWound]

Hi, Scott, and thank you. It's great to have you with us today. Maybe Hani, do you want to answer this question?

[Hani Luxenburg, CFO at MediWound]

Hi, Scott. Great to have you with us. Thank you for the question. Our guidance for 2024 remains with no change. Actually, we anticipate $24 million in total revenue. As you all are aware, the change in the U.S. administration caused a brief delay in the approval of both BARDA and DoD-funded activity during the transition. However, all programs now appear to be back on track, and we do not anticipate any material impact on our revenue, on our 2025 funding outlook. The outcome is that the revenue will not change for this year.

[Scott Henry, Managing Director and Senior Research Analyst at Alliance Global Partners]

Okay. Great. So, it sounds like we should expect that to rebound, if not the second quarter, certainly the second half of the year.

[Ofer Gonen, CEO at MediWound]

Yeah. Let me step here and clarify. In the first 60 days, the administration, they did not know what they can approve, what they cannot approve. Then it was a kind of uncertainty. The feedback that we are getting is everything, at least for our programs, is back on track, and we anticipate the $24 million guidance to remain as it is and the programs that they are funding as programs with a priority that will keep on getting the U.S. government funds.

[Scott Henry, Managing Director and Senior Research Analyst at Alliance Global Partners]

Okay. Great. Thank you for that color. Hani, since I have you there, could you talk a little bit about the below-the-line, below-the-operating income, that financial income expense line has been pretty volatile, certainly very positive in this quarter, more of an expense in the prior quarter. How should we think about that below-the-line expense, financial income expenses going forward? What's a representative number? Is there any noise in there?

[Hani Luxenburg, CFO at MediWound]

I wish I knew the representative number. If I knew it, I would not be here because it is very much influenced by our share price in the end of each quarter. Okay? The below-the-line expenses is mainly from the financial income or expenses from revaluation of our warrants. At the end of each quarter, we are doing revaluation, and it is very much depend on the share price, if it was increased or decreased from the beginning of the quarter, and this set the direction of the income or expense. Okay? At the end of this quarter, the share price was $15.52, much below what it is now. Okay? It is very much depend, and I cannot tell you what to expect. It is depend on the market.

[Hani Luxenburg, CFO at MediWound]

I hope we'll see a good transition in our share price, and it will set the opposite way because if it increases, there are expenses, financial expenses. If it decreases, there are financial income. I hope I answered.

[Scott Henry, Managing Director and Senior Research Analyst at Alliance Global Partners]

Yes. That is actually quite helpful. I'll just take a look at the filings where I'll get the greater detail. That is helpful. Thank you for that, and thank you for taking the question.

[Ofer Gonen, CEO at MediWound]

If I may add, those options expire in November 2026. These are $34 million of warrants that are way below the money. If you want to look at next quarter, you will see that there was a significant increase in the share price. Probably, there will be financial expenses related to that, but we are okay with that. Hopefully, after November 2026, this company will remain with no warrants, and this issue will disappear.

[Michael Okunewitch, Analyst at Maxim Group]

Okay. Great. Thank you for that color.

[Ofer Gonen, CEO at MediWound]

Okay. Thank you, Scott.

[Operator]

This concludes our question-and-answer session. I would like to turn the conference back over to Ofer Gonen for any closing remarks.

[Ofer Gonen, CEO at MediWound]

Okay. Thank you, everyone, for joining us today. We look forward to updating you again in our next quarterly call.

[Operator]

The conference is now concluded. Thank you for attending today's presentation. You may now disconnect.

Participants

Executives

• Barry Wolfenson, EVP of Strategy and Corporate Development
• Ofer Gonen, CEO
• Hani Luxenburg, CFO

Analysts

• Scott Henry, Managing Director and Senior Research Analyst at Alliance Global Partners
• Ramakanth Swayampakula, Managing Director at H.C. Wainwright & Co
• Michael Okunewitch, Analyst at Maxim Group
• Chase Knickerbocker, Analyst at Craig-Hallum Capital Group
• Dan Ferry, Managing Director at LifeSci Advisors