NASDAQ:BRKR Bruker Q1 2025 Earnings Report $36.33 -0.13 (-0.34%) As of 02:33 PM Eastern This is a fair market value price provided by Polygon.io. Learn more. Earnings HistoryForecast Bruker EPS ResultsActual EPS$0.47Consensus EPS $0.46Beat/MissBeat by +$0.01One Year Ago EPS$0.53Bruker Revenue ResultsActual Revenue$801.40 millionExpected Revenue$763.83 millionBeat/MissBeat by +$37.57 millionYoY Revenue Growth+11.00%Bruker Announcement DetailsQuarterQ1 2025Date5/7/2025TimeBefore Market OpensConference Call DateWednesday, May 7, 2025Conference Call Time8:30AM ETUpcoming EarningsBruker's Q2 2025 earnings is scheduled for Tuesday, August 5, 2025, with a conference call scheduled at 8:30 AM ET. Check back for transcripts, audio, and key financial metrics as they become available.Conference Call ResourcesConference Call AudioConference Call TranscriptSlide DeckPress Release (8-K)Quarterly Report (10-Q)Earnings HistoryCompany ProfileSlide DeckFull Screen Slide DeckPowered by Bruker Q1 2025 Earnings Call TranscriptProvided by QuartrMay 7, 2025 ShareLink copied to clipboard.PresentationSkip to Participants Operator00:00:00Good day, and welcome to the Bruker Corporation First Quarter twenty twenty five Earnings Conference Call. All participants will be in listen only mode. After today's presentation, there will be an opportunity to ask questions. Please note this event is being recorded. I would now like to turn the conference over to Joe Director of Investor Relations. Operator00:00:46Please go ahead. Joe KostkaDirector, Head of Investor Relations at Bruker00:00:50Good morning. I would like to welcome everyone to Bruker Corporation's first quarter twenty twenty five earnings conference call. My name is Joe Koska, and I am the Director of Bruker Investor Relations. Joining me on today's call are Frank Laukien, our President and CEO and Gerald Herman, our EVP and CFO. In addition to the earnings release we issued earlier today, during today's conference call, we will be referencing a slide presentation that can be downloaded from the Events and Presentations section of Bruker's Investor Relations website. Joe KostkaDirector, Head of Investor Relations at Bruker00:01:23During today's call, we will be highlighting non GAAP financial information. Reconciliations of our non GAAP to GAAP financial measures are included in our earnings release and are posted on our website at ir.bruker.com. Before we begin, I would like to reference Bruker's Safe Harbor statement, which is shown on Slide two of the presentation. During this conference call, we will make forward looking statements regarding future events and the financial and operational performance of the company that involve risks and uncertainties, including those related to our recent acquisitions, geopolitical risks, tariffs, market demand or supply chains. The company's actual results may differ materially from such statements. Joe KostkaDirector, Head of Investor Relations at Bruker00:02:06Factors that might cause such differences include, but are not limited to, those discussed in today's earnings release and in our Form 10 ks for the period ending 12/31/2024, as updated by our other SEC filings, which are available on our website and on the SEC's website. Also, please note that the following information is based on current business conditions and to our outlook as of today, 05/07/2025. We do not intend to update our forward looking statements based on new information, future events or for other reasons, except as may be required by law, prior to the release of our second quarter twenty twenty five financial results expected in early August twenty twenty five. You should not rely on these forward looking statements as necessarily representing our views or outlook as of any date after today. We will begin today's call with Frank providing an overview of our business progress and of the expected impacts from U. Joe KostkaDirector, Head of Investor Relations at Bruker00:03:03S. Policy changes and new tariffs. Gerald will then cover the financials for the first quarter of twenty twenty five in more detail and share our updated full year 2025 financial outlook. Now I'd like to turn the call over to Bruker's CEO, Frank Laukien. Frank LaukienChairman, CEO & President at Bruker00:03:21Thanks, Joe. Good morning, everyone, and thank you for joining us on today's first quarter twenty twenty five earnings call. Bruker had a solid start to 2025 with double digit reported and constant exchange rate or CER revenue growth. We also had 5.1% organic revenue growth in our Bruker Scientific Instruments segment and better operating margin performance than expected. In short, our teams executed very well under significant uncertainties in key markets. Frank LaukienChairman, CEO & President at Bruker00:03:53In the first quarter and in April at the important AGBT, E and C, ESKMET and AACR conferences at the Alphabet Soup, we launched a number of very innovative performance leading new products in spatial biology, cellular analysis, NMR, microbiology and molecular diagnostics, all strengthening our high value offerings in key areas of our strategic focus. I'll cover several of these important new products in a few moments, but the key message here is that in times of funding uncertainties and in particularly it is particularly important to enable our customers with unique and highly relevant new research and clinical capabilities. We also expect these meaningful post genomic innovations to drive continued higher revenue CAGR differentiation for Bruker beyond the present AKAgov headwinds in The U. S. And China. Frank LaukienChairman, CEO & President at Bruker00:04:53Let's begin on Slide four. With the performance of the business in Q1 twenty twenty five, then I'll walk you through the impact of recent U. S. Policy changes and the new tariff regime, how we anticipate it will impact Bruker and how we intend to mitigate the resulting headwinds to our margins slightly more than half in 2025 and then completely by 2026. On Q1 twenty twenty five performance, we delivered a stronger than expected first quarter. Frank LaukienChairman, CEO & President at Bruker00:05:23Bruker's Q1 '20 '20 '5 reported revenues increased 11% year over year to $801,400,000 above our preannounced range of $795,000,000 to $800,000,000 and significantly above prior expectations. Our constant exchange rate CER revenue growth was 12.5% year over year, including organic growth of 2.9% with, as I said earlier, a reasonably strong 5.1% organic growth delivered by our BSI segment and a 9.6% contribution to revenue growth from acquisitions. If you recall, we did some of our larger acquisitions last year in the second quarter. Notably, performance in the biopharma end markets strengthened in the quarter and grew in the mid single digits percentage. Our first quarter twenty twenty five non GAAP operating margin was 12.7%, which was down year over year due to the expected M and A dilution from the strategic acquisitions I just mentioned that we completed in Q2 twenty twenty four. Frank LaukienChairman, CEO & President at Bruker00:06:32However, underneath we again posted strong organic operating profit margin expansion of about 100 basis points year over year in the quarter. Our first quarter twenty twenty five diluted non GAAP EPS was $0.47 down from $0.53 in Q1 twenty twenty four due to expected and more recent FX currency headwinds. Please turn to slides five and six, where we highlight the first quarter CER performance of our three Scientific Instruments groups and of our BEST segment year over year. In Q1, BioSpin revenue was $2.00 $8,000,000 with mid teens percentage CER growth. BioSpin growth was driven by strong ACCA gov revenue including an ultra high field NMR system in The UK, by industrial research and food safety markets and a strengthening biopharma environment, as well as strong contributions from preclinical imaging and lab automation, the new ChemSpeed business. Frank LaukienChairman, CEO & President at Bruker00:07:38In Q1, our CALID group had revenue of €280,000,000 with mid-20s percentage CER growth. CALID growth was led, as you might expect, by microbiology and infection diagnostics, including the acquired ElliTech molecular diagnostics business as well as double digit plus growth in life science mass spectrometry driven by strength in the timsTOF platform. CALID saw robust growth in Europe and The Americas and strength in clinical, industrial and biopharma applications, while agarGalp performance was moderate. Turning to slide six. In Q1, Bruker Nano revenue was $257,000,000 with CER revenue growth up high single digits percentage. Frank LaukienChairman, CEO & President at Bruker00:08:30Growth was supported by inorganic revenue growth from NanoString, which was not yet included in Q1 of twenty twenty four, the year over year comparison. Strength in APAC ex China, Biopharma and agagav markets were partially offset by softness in Europe and China as well as in X-ray and nanoanalysis tools. Finally, first quarter BEST CER revenues declined in the high teens percentage net of intercompany eliminations as our Research Instruments business saw weaker performance in the quarter. They had a very strong prior year comparison. And that also was combined with continued softness in the superconductor market for clinical MRI. Frank LaukienChairman, CEO & President at Bruker00:09:18Moving to slide seven, we highlight the recent innovations underscoring Bruker's leading commitment to advancing spatial biology announced first at AGBT and then expanded further at AACR in Chicago in late April. There's a lot of information on slide seven. Don't worry, I won't read it all. But it gives you a highlight it gives you an idea about the breadth and depth and best in class performance of each platform, each significantly enhanced in terms of content or sensitivity or throughput and of course the completely unique paintscape. Maybe one theme that comes here throughout is that Spatial is going multi omics. Frank LaukienChairman, CEO & President at Bruker00:10:07Both our GeoMx platform now allows HyFlex transcriptomics, of course, that's what we're known for, but also tissue proteomics. And that's also, by the way, true for our non spatial nCounter system that you may recall from the NanoString days. CosMiX with the old transcriptome panel now that is ready for orders where we can really get 19,000 protein encoding genes at the transcriptome level is an unmatched research tool. And importantly, we've increased our detection efficiency by a factor of 2x, one of the areas that was that the customers were waiting for. Too much detail, let me move on to Slide eight. Frank LaukienChairman, CEO & President at Bruker00:10:56Eight is an important acquisition, gets us into a different branch of Diagnostics. This is not microbiology, infectious disease and it very much fits with our triple quadrupole mass spec strategy, which of course is very differentiated with our particular claim to fame and focus to chromatography free or chrome free point of need mass spectrometry using triple quad targeted technology. This gives us the crucial assays and kits and consumables business. Recife is based in Munich, been in business for over forty years. Revenue is a little greater than €15,000,000 very profitable. Frank LaukienChairman, CEO & President at Bruker00:11:37And for the European market, it gives us the therapeutic drug monitoring and other kits for IBD and other things that we don't need to go into detail. This combination kits, assays, contents with a diagnostic focus for therapeutic drug monitoring and also by the way eventually drugs of abuse because it cannot be so fast and inexpensive with the DART chrome free approach is actually strategically quite exciting to us. And we think these two instruments plus assays and diagnostics coming together is a nice is an important additional growth trajectory for the company. But we know you want to hear about the macro and ACOGov, so let's go into it. Let me make sure I'm on the right slide. Frank LaukienChairman, CEO & President at Bruker00:12:24Yes, I will now review our assessment and anticipated impact from U. S. Policy changes regarding federal funding for academic research and the current tariff regime on Bruker for the remainder of 2025. Moreover, I will provide an overview of our additional cost initiatives, new pricing actions and already ongoing and now accelerating supply network reengineering to partially mitigate at least half of the new headwinds in this year fiscal twenty twenty five and then more fully in fiscal twenty twenty six. So here we go. Frank LaukienChairman, CEO & President at Bruker00:13:03Our initial estimates are that U. S. Policy changes to federal research funding, lower China stimulus funding release and some temporary revenue impact of new China tariffs on revenue will amount to an approximately €100,000,000 gross headwind to our organic fiscal year twenty twenty five revenues before some mitigation. You cannot mitigate that much on the revenue side, but a little bit. Anyway, this €100,000,000 fiscal year 20 20 5 revenue headwind is broken into three buckets. Frank LaukienChairman, CEO & President at Bruker00:13:41First, and that's a smaller and transient one, some fiscal year twenty twenty five China revenues that were to be shipped from The U. S. May be delayed are delayed by customers or may be partially canceled due to the current 125% Chinese import tariffs on U. S. Goods. Frank LaukienChairman, CEO & President at Bruker00:14:00We're working with our customers to partially mitigate this impact with supply chain alternatives, tariff extensions or delivery delays with the largest transient impact now expected in the second quarter of twenty twenty five. Then second, the strongest, but by far the strongest revenue headwind this year not surprisingly is related to U. S. Aga Gov markets as a result of research funding policy changes. For Bruker, we now expect U. Frank LaukienChairman, CEO & President at Bruker00:14:31S. Aga gov revenue to be down 20% to 25% for this year. U. S. Agagav in fiscal year twenty twenty four had grown to about 10% of overall Bruker revenues. Frank LaukienChairman, CEO & President at Bruker00:14:45And in the updated guidance, we assume that the current academic funding uncertainty continues even though we acknowledge there's some potential upside in the second half of twenty twenty five if NIH and NSF and DOE R and D grants begin to flow again without further delays. Anyway, we have not baked those in. So hopefully this is a floor. Finally, we do not think that the President's initial budget request for NIH and NSF will be passed by Congress as is without an improvement. We expect it to be down, but not as much as the opening bid. Frank LaukienChairman, CEO & President at Bruker00:15:22Third, a headwind related to anticipated China AGAGRAPH revenue as funding of the stimulus programs China has been slow to be released by the provinces. Many shovel readying projects, lot of them with our instrumentation, high end Accagov, but slow to release as they're probably watching tariff and trade wars. This may improve throughout 2025, but at the moment timing and amounts are uncertain. So there are a number of moving parts that could provide additional upside such as release of China stimulus funding, German and South Korean stimulus funding, European defense and security investments, we see some of that, and further semiconductor metrology strength due to the AI machine learning trends, which we which are very profitable for us. So these factors could add upside, but we have not built them into our guide assumptions, hoping to provide a floor for 2025 with upside in any case more likely to benefit fiscal twenty twenty six. Frank LaukienChairman, CEO & President at Bruker00:16:30We also note that uncertainty around potential U. S. Tariffs on pharma products could slow the encouraging recovery that we have seen in drug discovery and development markets in the last two quarters. And again, we have tried to take that into account in our guidance. So that was the revenue piece. Frank LaukienChairman, CEO & President at Bruker00:16:47Let's move to operating profit or margins. So with respect to 25,000,000 operating profit, the gross headwinds before our mitigation actions are pretty meaningful. So first of all, the roughly $100,000,000 of produced organic revenue previously noted is expected to lead to about a $50,000,000 reduction in $25,000,000 operating profit. Moreover, Bruker imports about 75% of our U. S. Frank LaukienChairman, CEO & President at Bruker00:17:14Product revenue, obviously not the services revenue, there's another piece to it. But of our product revenue, 75% is imported largely from the European Union and Switzerland, but also from Israel and Malaysia. The current U. S. Import tariff rate of 10% from those countries would result in an additional headwind of at most of about $40,000,000 to operating profit for the remainder of $2,025,000,000 again before our ongoing mitigation actions. Frank LaukienChairman, CEO & President at Bruker00:17:44That's a gross headwind. U. S. Tariffs on imports from China for Bruker have a negligible effect on Bruker excluding some secondary supply chain inflationary effects, but we basically don't import any products from China. So in total, we therefore estimate gross headwinds for our twenty five percent operating profit primarily from U. Frank LaukienChairman, CEO & President at Bruker00:18:08S. Aga gov disruption and new tariffs to be about $90,000,000 altogether before our mitigation actions. Now deploying our Bruker management process and strong leadership team that as you've seen has been really excellent executing very well not only this year, but for many years. We have already taken and are taking numerous actions to offset more than half of these margin headwinds this year with the remainder expected to be fully effective next year in 2026. Our mitigation actions include new pricing actions, additional cost cutting initiatives and supply network and manufacturing reengineering. Frank LaukienChairman, CEO & President at Bruker00:18:50We estimate these mitigation measures will offset slightly more than half of the operating profit headwind for 2025. We then expect to fully offset these headwinds through price, cost and supply network and manufacturing reengineering by 2026. Fortunately, we're a very international company with a lot of flexibility, but it takes a little bit of time. Anyway, factoring in U. S. Frank LaukienChairman, CEO & President at Bruker00:19:15Agagav and tariff headwinds as well as the recent weakening of the U. S. Dollar, a significant effect as well as our mitigation actions and taking it all into our updated fiscal year twenty twenty five non GAAP EPS projections leads us to a new guidance range for EPS of $2.4 to $2.48 So in summary, Bruker delivered strong CER growth and organic operating margin expansion in the first quarter of twenty twenty five. We're experiencing new headwinds as a result of ACAGOL policy changes and tariffs. As always, we remain agile in responding to the evolving dynamics. Frank LaukienChairman, CEO & President at Bruker00:19:56Our management process is navigating us through these headwinds in 2025 and setting us up for resuming margin expansion and strong EPS growth in 2026 and beyond. So with that, let me turn the call over to Gerald, our CFO, who will review our financial performance in more detail and provide further color on our updated outlook for 2025. Gerald, go ahead please. Gerald HermanExecutive VP & CFO at Bruker00:20:21Thank you, Frank, and thank you everyone for joining us today. Pleased to provide more detail on Bruker's first quarter twenty twenty five financial performance, starting on Slide 10. In the first quarter of twenty twenty five, we had another quarter of excellent execution, delivering a strong first quarter above our earlier expectations and the color provided to the investor community. In the first quarter of twenty twenty five, Bruker's reported revenue increased 11% to $801,400,000 which reflects an organic revenue increase of 2.9% year over year. Acquisitions added 9.6% to our top line, while foreign exchange was a 1.5% headwind, resulting in constant exchange rate revenue growth of 12.5% year over year. Gerald HermanExecutive VP & CFO at Bruker00:21:08Geographically and on a year over year organic basis in the first quarter of twenty twenty five, our Americas revenue declined in the low single digits percentage. European revenue grew in the mid single digits percentage, while Asia Pacific revenue grew in the low single digits percentage despite a 10% decline in China. For our EMEA region, revenue was up mid teens percentage. We delivered strong BSI organic revenue growth in the first quarter of twenty twenty five at 5.1%, driven by strength in our bBio and CALID groups. BSI Systems grew in the mid single digit range and BSI Aftermarket revenue grew in the high single digit range organically year over year. Gerald HermanExecutive VP & CFO at Bruker00:21:55Our order book performance in our BSI segment was down slightly compared to the prior year first quarter with softer academic government orders in The U. S. And in China. Non GAAP gross margin increased 10 basis points to 51.3%. In Q1 twenty twenty five, non GAAP operating margin was 12.7, which included 100 basis points of organic operating margin expansion on better mix and cost control, more than offset by planned M and A dilution as Q1 twenty twenty four did not include two of our largest strategic acquisitions that closed in the second quarter of twenty twenty four. Gerald HermanExecutive VP & CFO at Bruker00:22:38On a non GAAP basis, Q1 of twenty twenty five diluted EPS was $0.47 down 11.3% from the $0.53 we posted in the first quarter of twenty twenty four, which did not yet include our key acquisitions last year. Our non GAAP effective tax rate was 27.7% compared to 26.7% in the first quarter of twenty twenty four, with the increase driven mostly by an unfavorable discrete item. On a GAAP basis, we reported diluted EPS of zero one one dollars compared to $0.35 in the first quarter twenty twenty four. Weighted average diluted shares outstanding in the first quarter twenty twenty five were 151,900,000.0, an increase of 6,000,000 shares or 4.1% from the first quarter of twenty twenty four, resulting from our follow on equity offering in May of twenty twenty four. Turning now to slide 11. Gerald HermanExecutive VP & CFO at Bruker00:23:36We generated $65,000,000 of operating cash flow in the first quarter of twenty twenty five. Our capital expenditure investments were $26,000,000 resulting in free cash flow of $39,000,000 in the first quarter of twenty twenty five. This reflects an improvement in free cash flow of about $39,000,000 over the first quarter of twenty twenty four, driven by better working capital performance in the quarter. We finished the first quarter with cash, cash equivalent and short term investments of approximately $184,000,000 During the first quarter, we used cash to fund capital expenditures, select Project Accelerate two point zero initiatives and debt repayments. Turning now to slide 13. Gerald HermanExecutive VP & CFO at Bruker00:24:20As Frank noted earlier, we're updating our fiscal year twenty twenty five outlook to reflect a strong first quarter and the impact of recent policy changes and tariffs. We now expect reported revenues of 3,480,000,000.00 to $3,550,000,000 representing reported growth of 3.5% to 5.5%. This guidance assumes organic revenue growth of 0% to 2%, an estimated tailwind from foreign exchange of about 1% and acquisitions to contribute approximately 2.5% to revenue growth. This implies constant exchange rates ER revenue growth of 2.5 to 4.5% all year over year. The revenue guidance includes an organic revenue gross headwind of approximately $100,000,000 from recent policy changes and tariffs, partially offset by pricing and other mitigation actions of about $20,000,000 for a net headwind of about $80,000,000 We now expect our fiscal year twenty twenty five operating margin to be roughly flat year over year with organic improvement of greater than 70 basis points including mitigation actions to be roughly offset by headwinds from M and A and foreign exchange. Gerald HermanExecutive VP & CFO at Bruker00:25:41Recent policy changes, academic government market weakness in The U. S. And China, together with the current level of U. S. And China import tariffs are assumed to be a $90,000,000 gross headwind to operating profit in fiscal year twenty twenty five. Gerald HermanExecutive VP & CFO at Bruker00:25:58We anticipate over half of this impact to be offset through our mitigation actions, including pricing about £10,000,000 cost management about £30,000,000 and supply chain reengineering about 10,000,000 already in fiscal year twenty twenty five. On the bottom line, we're now guiding to non GAAP EPS for 2025 in a range of $2.4 to $2.48 This translates to roughly non GAAP EPS growth of 0% to 3% compared to 2024. Given the recent weakening of the U. S. Dollar against major currencies, foreign exchange is now a 5% headwind to our non GAAP EPS, implying constant exchange rate non GAAP EPS growth of 5% to 8% for fiscal year twenty twenty five. Gerald HermanExecutive VP & CFO at Bruker00:26:48Other guidance assumptions are listed on the slide. Please note our fiscal year twenty twenty five ranges have been updated for foreign currency rates and tariff rates as of 04/30/2025. While there are other policy and macroeconomic risks that could further impact our fiscal year twenty twenty five financial performance, with this updated guidance, we hope to have established a floor based on current headwinds and our robust mitigation actions. Given the lower base years of 2024 and 2025, it's now become clear that our previously communicated medium term outlook targets are not likely to be realized under our originally planned cadence. We intend to provide updated medium term outlook targets when we have a clear line of sight on U. Gerald HermanExecutive VP & CFO at Bruker00:27:36S. Federal research policy and funding and stabilized tariffs. Fundamentally, we remain optimistic that we've transformed Bruker's portfolio for above market revenue growth, rapid margin expansion towards the mid-twenty percent operating margins and mid high teens EPS growth once new headwinds abate. Finally, to add color on the second quarter of twenty twenty five, given softer U. S. Gerald HermanExecutive VP & CFO at Bruker00:28:05And China academic government market conditions and some U. S. Produced China revenue likely delayed from the second quarter, we expect our second quarter twenty twenty five organic revenue to decline in the low single digits, while constant exchange rate revenue is expected to increase in the low single digits percentage both year over year. In the second quarter of twenty twenty five, we also expect to see a transient year over year decrease in non GAAP operating margin and non GAAP EPS performance, with significant improvements in both metrics expected in the second half of this year. To wrap up, Bruker delivered a solid BSI organic revenue growth and organic operating margin expansion in the first quarter twenty twenty five under uncertain conditions. Gerald HermanExecutive VP & CFO at Bruker00:28:57Moving forward, we remain confident in our ability to continue to execute well under a challenging environment. And with that, I'd like to turn the call over to Joe. Thank you very much. Joe KostkaDirector, Head of Investor Relations at Bruker00:29:09Thanks, Gerald. I'd now like to turn the call over to the operator to begin the Q and A portion of the call. Operator00:29:24We will now begin the question and answer session. Our first question comes from Puneet Souda of Leerink Partners. Go ahead please. Puneet SoudaSenior MD at Leerink Partners00:30:09Frank. Thanks for the questions here and thanks for all the details on the tariffs for quantifying that. Could you elaborate if there was any pull forward in the quarter because of the tariffs worries or any other worries in the market that the customers might have had? And are you baking any impact from that as a result of that pull forward? And then in China, I appreciate you mentioned cancellations, but are you seeing any cancellations in The U. Puneet SoudaSenior MD at Leerink Partners00:30:42S. Or European markets, specifically maybe around UHF gigahertz magnet? I didn't hear guidance on that for the year. Frank LaukienChairman, CEO & President at Bruker00:30:53Okay, Puneet. Thank you. So there really wasn't any pull forward that's being talked about due to tariffs or AGA gap. We didn't see that. However, we acknowledge that The U. Frank LaukienChairman, CEO & President at Bruker00:31:07K. One Point Two gigahertz system that we had expected for Q2, It just technically, it just went in easily and so it got in Q1. That wasn't a pull forward. That was just a really smooth installation. So that helped Q1 a little bit and of course I wouldn't call it a pull forward. Frank LaukienChairman, CEO & President at Bruker00:31:30It was not a market driven pull forward. To cancellations, we don't really see any China cancellations yet. Customers who don't have the budget to pay the extra 125% for which they according to the terms would be mostly we think would be on them, but they just don't they presently right now are a little bit in this holding pattern. Hey, don't ship yet. We can't accept it because we can't pay the import duties. Frank LaukienChairman, CEO & President at Bruker00:32:01It's not a big effect, but of course in Q2 it's going to be noticeable as Gerald explained. We do not see any cancellations. We see lots of uncertainties and delays in The U. S. And AGAGOV. Frank LaukienChairman, CEO & President at Bruker00:32:13We haven't seen any cancellations because of that. No cancellations yet in China, but delays. And in some cases, we are also simply rerouting and maybe building some of these systems in Europe or Malaysia. So hopefully, we can mitigate, but sort of typically with a quarter's delay. Puneet SoudaSenior MD at Leerink Partners00:32:37That's helpful. Frank LaukienChairman, CEO & President at Bruker00:32:38Hopefully, are two questions. Yes. Puneet SoudaSenior MD at Leerink Partners00:32:40Yes. Puneet SoudaSenior MD at Leerink Partners00:32:41Thank you. And then when we think about the offsets, obviously, a lot of challenges in the market today. But when we think about the offsets, the AI chips, onshoring of that, the funding initiatives in Germany, maybe lower interest rates. Can you walk us through how are you thinking about some of those offsets potentially sort of mitigating the impact maybe into the second half? Frank LaukienChairman, CEO & President at Bruker00:33:13Yes. In terms of orders, they may I mean AI remains very strong in our tools. I mean of course, there's more important partners. But without us, the AI revolution also wouldn't work, right? TMSC absolutely needs our tools. Frank LaukienChairman, CEO & President at Bruker00:33:30I think they are single largest customer in the world at this point. Of course, they're doing a lot of work both in Japan and in The U. S. They're upgrading and investing in Taiwan. So that remains strong and has remained strong. Frank LaukienChairman, CEO & President at Bruker00:33:43In fact, for AI driven bookings in Q1 were quite strong. So that's strong. And a lot of the delivery times for these things are longer. When their fab is ready middle of next year, you can't really ship it earlier. German and Korean and similar stimulus funding or European defense fund spending. Frank LaukienChairman, CEO & President at Bruker00:34:04The timelines, these are all good trends. Some of them are beginning to turn into orders. Some of them just are very encouraging in Germany, would say. That's nearly 10% of our revenue in typical years. But I don't think they'll make much of a difference anymore in revenue and in our P and L this year. Frank LaukienChairman, CEO & President at Bruker00:34:25They are, however, welcome tailwinds for 'twenty six and even into 'twenty seven, 'twenty eight. So AI will help us also this year. Although if I take an order today, it's probably for next year, but I have orders that I can ship this year and that continues to be strong demand. And yes, the onshoring in Japan, in The U. S, also in Europe plays a role, but that's also very significant continued investments by the leading technologically leading companies in Taiwan and in Korea. Frank LaukienChairman, CEO & President at Bruker00:35:01So that's actually quite good. Puneet SoudaSenior MD at Leerink Partners00:35:05Helpful. I'll hop back into the queue. Thank you. Frank LaukienChairman, CEO & President at Bruker00:35:08Thank you, Puneet. Operator00:35:12The next question comes from Michael Ryskin of BoA. Go ahead please. Michael RyskinManaging Director at Bank of America Merrill Lynch00:35:18Great. Thanks for taking the question. Frank, I want to talk about a comment you made towards the end of the prepared remarks in terms of medium term guide being a little bit unrealistic in the current environment. So if we just focus on The U. S. Michael RyskinManaging Director at Bank of America Merrill Lynch00:35:30Policy changes, you mentioned Trump's initial proposal is 40% cut. You don't think that will happen because Congress will offset. But let's say it's 20%, twenty five % cut to next year's budget, to pick a number similar to what your assumption is for this year. How does Bruker offset that next year? Could you talk about how you would respond? Michael RyskinManaging Director at Bank of America Merrill Lynch00:35:51What different levers you are? How we should think about possible ways to get around that, whether it's pharma biotech, whether it's Puneet just asked on AI and some of that, some of the more industrial tech parts of the business. Just sort of what steps would you take to offset that U. S. A and G cut that would be a little bit more medium term? Frank LaukienChairman, CEO & President at Bruker00:36:13Yes. No, you listed most of them. So I'll as you've seen our twenty four mid-twenty four medium term outlook, '24, '20 '5 to '2 base years have obviously changed. That's what we're talking about. So therefore, we'll look we are very committed to resuming very significant margin expansion this year. Frank LaukienChairman, CEO & President at Bruker00:36:38All that we had a lot more than the 140 bps lined up, and we're hoping to do much better than that. Turns out this year, we're kind of moving sideways because we're using all of these improvements plus new cost and pricing and supply chain actions to just deal with the headwinds this year. So but assuming no new, new headwinds by 2026 and beyond, think this operating model, operational excellence integration that all still works, but it kind of takes with a one year shift because this year we're playing defense quite honestly. Right. I think all these trends that you did mention, biopharma has been picking up nicely. Frank LaukienChairman, CEO & President at Bruker00:37:19Our tools for biopharma, including those from spatial biology and beacon cellular analysis, You've seen we've not just done cost cuts, we've done incredible fantastic fast product development to resume growth in these businesses when the headwinds abate, right? We're doing very well with AI. Then we just discussed that with Puneet and you asked about it, that's doing well. European security and defense spending, European investment quite honestly, infusion research, other clean energy projects are all helping us. So there's a lot of good growth drivers that are a little bit overshadowed this year, but that I think will play a bigger role next year. Frank LaukienChairman, CEO & President at Bruker00:38:02There's also some transient effects that we've explained a little bit that just go away. Your estimate that I don't know where NIH and NSF funding comes out once it gets through Congress. I'm pretty sure it's not the opening bid. Would it be but I think it will be down. I agree with you, it will be down. Frank LaukienChairman, CEO & President at Bruker00:38:20Maybe just not as deeply as proposed by the White House initially. But there are many other. I mean, Germany is not only looking at defense, they're really looking at significant R and D and innovation infrastructure and tools investments and other the weakness of the America academic system. There will be other countries that try to, well, quite honestly exploit that a little bit and say, oh, great, we can get some researchers. Let's give them a start up budget. Frank LaukienChairman, CEO & President at Bruker00:38:49So you see some of that dynamics. There's a lot of growth drivers that just most we're not baking them in this year even if they help us a little bit in the second half. Mostly I think it will be on orders And we're just trying to set ourselves up for giving a baseline for 25,000,000 moving sideways a little bit with some organic growth and a little bit of EPS growth. Actually EPS growth excluding currency is reasonable for us this year and what we're projecting and then really fully resuming fast margin expansion EPS growth etcetera next year. Michael RyskinManaging Director at Bank of America Merrill Lynch00:39:25Okay. That's all really helpful. Michael RyskinManaging Director at Bank of America Merrill Lynch00:39:27And then Gerald if I could squeeze in a follow-up for you. You mentioned the comments in your prepared remarks about order book and BSI down year over year on ANGI in U. S. And China. Obviously, makes sense given what's going on there. Michael RyskinManaging Director at Bank of America Merrill Lynch00:39:39Anyway, you could quantify that either via book to bill or just an order growth number? And then could touch on your backlog, your existing backlog ability to offset maybe a lower order book in 1Q, 2Q this year, just sort Michael RyskinManaging Director at Bank of America Merrill Lynch00:39:56of what that buffer gives you? Michael RyskinManaging Director at Bank of America Merrill Lynch00:39:58Thanks. Gerald HermanExecutive VP & CFO at Bruker00:40:01With respect to the order performance in the first quarter, was actually just slightly under the first quarter of twenty twenty four. The general composition of that was while we did see a slightly weaker performance in academic and government research sectors in both China and The U. S, we saw strength actually in biopharma and in some of the industrial markets, including semi of course. So I think generally speaking, right now, we are reasonably well positioned on the order book in order for us to continue to these orders, of course, benefit as you march into the second half of twenty twenty five and further into 2026. So I think generally speaking, our general position is we're feeling pretty good about that. Gerald HermanExecutive VP & CFO at Bruker00:40:49I would say on the backlog, we are still at seven months on a backlog level. So we do have some remaining backlog to be able to pull on in some of these quarters. We didn't see much decrease in the backlog drawdown level in the first quarter. So we'll see how this all plays out over the next couple of quarters. But fundamentally, we still have quite a bit of backlog to be able to pull on. Gerald HermanExecutive VP & CFO at Bruker00:41:15So I think that's the high level view, Brian. Frank LaukienChairman, CEO & President at Bruker00:41:18And BSI book to bill just below 0.95, not great, a little weaker in March as you would have expected, which is fits the overall pictures as expected, not great, not bad. Great. Thanks a lot guys. I'll leave it there. Appreciate it. Gerald HermanExecutive VP & CFO at Bruker00:41:36Sure. Operator00:41:40The next question comes from Patrick Donnelly of Citi. Go ahead please. Patrick DonnellyManaging Director at Citi00:41:47Hey, good morning guys. Maybe one more on the tariff side, encouraging to hear you guys offsetting that for 2026. Can you just talk through it sounds like pricing, cost initiatives, moving to manufacturing around, supply chain management. Can you just talk through, I guess, the new pricing assumptions, what you're doing on the manufacturing side? Just want to talk through that confidence level of offsetting it into 2026 and preserving that number and again kind of moving into 2026 with a clean slate on the tariff offsets. Patrick DonnellyManaging Director at Citi00:42:16If you could just talk through pricing, manufacturing cost initiatives that you're using to offset it. Frank LaukienChairman, CEO & President at Bruker00:42:23Yes. Patrick, thank you. Good questions. So pricing, yes, we're taking some U. S. Frank LaukienChairman, CEO & President at Bruker00:42:31But also some worldwide additional pricing action. I think for competitive reasons, we'd like to not go into that. It's not across the board, right? You kind of do it in a way that's smart and like all other companies. In terms of supply chain, yes, certainly the usual things that you do as an international company, I mean, are some products that you can do the final assembly and systems test. Frank LaukienChairman, CEO & President at Bruker00:42:59We can do it in The U. S. Or we can do it in Europe or we can do it in our Malaysia, Penang Malaysia major manufacturing centers. And we're exploring all of that and looking at all of that. Vice versa, we used to do X-ray and mass spec and NMR final assembly and systems test in The U. Frank LaukienChairman, CEO & President at Bruker00:43:20S. We're talking to third party trusted contract manufacturers that are international that we're already using either in Malaysia or in Europe quite honestly. And they have one of them has a facility here in New Hampshire and others have other U. S. Facilities about onshoring parts of our production even. Frank LaukienChairman, CEO & President at Bruker00:43:44And for that, of course, we also need a little bit more visibility about where transatlantic tariffs or respect to Israel and Malaysia end up. Right now, we assume existing tariff rates, which may not be a bad assumption for where things end up, but then again nobody is entirely sure. And yes, cost actions, think, Gerald mentioned those. The additional cost actions, We expect this year to amount to about $30,000,000 so pretty aggressive. And by the way, we didn't wait for that. Frank LaukienChairman, CEO & President at Bruker00:44:17That has started actually that started some of it has started right at the beginning of the year because we wanted to overperform our initial guidance. And then more of that has been significantly accelerated as more clouds moved in. And so yes. And so here, that's the cost actions are significant. The supply chain, you don't see such a big number, 10,000,000 this year, but that has a little bit more of a delayed effect. Frank LaukienChairman, CEO & President at Bruker00:44:48That will be a much bigger effect next year. Patrick DonnellyManaging Director at Citi00:44:53Okay. That's helpful. And then maybe a bit of a follow-up on Mike's question there. When you think about the academic market, Frank, I know you're talking about academic government, think, down 20%, twenty five % this year. I guess when you look forward, Gerald mentioned that mid- high teens earnings once these headwinds are absorbed, are you thinking that the academic market one of the big questions we get is, is this structural for the next few years, right, where this declines every year for the next few years? Patrick DonnellyManaging Director at Citi00:45:19Or is it you rebase this year and then have opportunity for that piece to grow? How do you think about the academic government exposure here? And is this, again, with the new administration in office, is this structural until things change on that front over the next few years? Frank LaukienChairman, CEO & President at Bruker00:45:35Yes. We still assume that U. S. Aga gov will be weak on the weaker side next year. Of course, we don't have straight visibility about some of the budget negotiations. Frank LaukienChairman, CEO & President at Bruker00:45:47I know they'll be negotiated, but I don't think that Congress will then say, hey, never mind, Mr. President, we're going to have an NIH budget increase. But probably hopefully a lesser decrease. Other things, of course, I mean, ACA gov 75% of the ACA gov market for us worldwide is outside The U. S. Frank LaukienChairman, CEO & President at Bruker00:46:13That's doing well. There's even some stimulus funding. There is some that's actually one of the better pieces of our demand. In The U. S, we also expect it to be weak, but probably growing compared to this year's more disrupted aga gov market, where there's also been the delays and the arguments over what's allowable overhead and indirect cost and then certain universities being in political fights with and some of them are big, right? Frank LaukienChairman, CEO & President at Bruker00:46:44Some of them that's not insignificant. So I think some of that we believe will be somewhat temporary, although temporary not one or two quarters, but for this year. And we still expect some weakness next year, although probably growth year over year compared to this year in The U. S. Like I got. Frank LaukienChairman, CEO & President at Bruker00:47:04Right? Understood. Thanks. Thank you, Patrick. Operator00:47:11The next question comes from Tycho Peterson of Jefferies. Go ahead please. Tycho PetersonManaging Director, Global Equities at Jefferies Financial Group00:47:17Hey. Thanks. Frank, I wanna dig into your pharma comments. You mentioned strengthening biopharma a few times. So did it get better as the quarter progressed? Tycho PetersonManaging Director, Global Equities at Jefferies Financial Group00:47:25Anything you can say in April? Is that mostly timsTOF? And in your guidance you alluded to maybe baking in some pharma slowdown. Maybe just talk about the gives and takes. Frank LaukienChairman, CEO & President at Bruker00:47:37Yes. Biopharma as you know we're partly in the late regulated but mostly in the drug discovery and development. Yes, biopharma has been increasing from a weak base last year or before that even. Biopharma has been had trended very nicely for us in Q4 already and in Q1. I don't really for us because we're not primarily consumables April, I can't comment. Frank LaukienChairman, CEO & President at Bruker00:48:02Taking that in and knowing that there's a threat of biopharma tariffs, we have put in a moderated recovery, a dampened recovery in biopharma, but not it falling back into a hole as it was maybe a year ago or so. TimsTOF NMR, but also a little bit of spatial, of course, our cellular analysis, beacon tools now that we have the new benchtop discovery system. There is a we're having more and more we're not a one trick pony or a two trick pony in biopharma anymore. So there's a lot of tools, including some process analytical tools and things like that, ProcessRama and some of the automation things from our ChemSpeed acquisition, some of the software that all supports efficiency and productivity and investments in pharma towards the digital lab and maybe eventually the lights out lab and things like that. So we have a bunch of things that are driving It's not only a one or two product story anymore, and that's all been reasonably healthy. Frank LaukienChairman, CEO & President at Bruker00:49:13Actually, it's been quite healthy the last two quarters. Tycho PetersonManaging Director, Global Equities at Jefferies Financial Group00:49:17That's helpful. And then follow-up on m and a. You know, you're adding the the Rossipee deal just over 15,000,000 or so in revenues, but you're not really changing your contributions here. It was two to three before, and now it's two and a half. So maybe just talk a little bit about, you know, what what the offsets are, on m and a. Tycho PetersonManaging Director, Global Equities at Jefferies Financial Group00:49:33And are you kind of more optimistic on revenue synergies from some of the deals, maybe just a scorecard now that we're kind of a year into Frank LaukienChairman, CEO & President at Bruker00:49:43ChemSpeed is doing great, better than expected with its automation demand in pharma So very happy with that. Elitech, my god, the most predictable business ever and they're doing well. And in fact, they did well again in Q1. So that's a good space and they're doing a little better than our acquisition model. Frank LaukienChairman, CEO & President at Bruker00:50:02They also did better last year in getting more platforms out that then over the first year of the deployment that's when the consumables pull through grows as they add more and more assays. Spatial biology and cellular analysis, they both suffered from weak pharma this year and they're both suffering a little bit from weak academic this year. And of course, it gets harder to export things to China when there's 125% increase. So there we're making great progress on taking cost out on efficiency, on putting in a new management process, amazing progress in new competitive products from cellular analysis and spatial biology, but they're both somewhat weaker than what we had expected because of course the U. S. Frank LaukienChairman, CEO & President at Bruker00:50:50ACOGARF this year they both noticed that even as biopharma which was weaker last year is recovering. So that's sort of muted, but I think we're still on track there for looking at a 26 breakeven for these two businesses. Was a quick rundown Tycho. Operator00:51:15The next question comes from Rachel Bedstow of JPMorgan. Go ahead please. Rachel VatnsdalSenior Equity Research Analyst, Healthcare at JPMorgan Chase00:51:22Perfect. Good morning. Thanks so much for taking the questions. So I wanted to follow-up on Mike's earlier question around order book trends. Appreciate all the color you gave us on orders in the quarter and book to bill as well. Rachel VatnsdalSenior Equity Research Analyst, Healthcare at JPMorgan Chase00:51:32But can you talk to us about your expectations for bookings going forward? Do you think we've kind of hit the bottom on orders? Are you expecting it to get worse as we get into the second, third quarter given some of the headlines on NIH budget proposals? And then where are you expecting to exit this year on backlog given you said you still have the seven months of backlog that you're working with? Frank LaukienChairman, CEO & President at Bruker00:51:53I think the academic order weakness I think is just beginning. Q1 or maybe March we saw just a little bit of that. But so U. S. Academic orders and a lot of that headwind this year I think you'll see that in weak U. Frank LaukienChairman, CEO & President at Bruker00:52:09S. Academic government orders in The U. S. In Q2, probably in Q3. And yes, we'll see whether there is some budget flush and grants moving through finally with much delay. Frank LaukienChairman, CEO & President at Bruker00:52:24So but so I think the brunt of that is now coming in Q2 and Q3, hence the revenue headwind that we've taken into account in this new guidance and that we've explained. We have enough other strength in our forecast that we still think will come out at the end of the year with a six point five to seven months backlog. So I know we're all focused on U. S. Aga gov and every day there's a usually not very nice headline. Frank LaukienChairman, CEO & President at Bruker00:52:53But there is other stuff that we do and we are so diversified and so international that we actually still we think our long term normalized backlog should be around 5x now that we have much more consumables and aftermarket that's a little lower than historically when we would have said 5.5x. And I think at this end of this year we'll almost certainly be at 6.5% possibly still at 7%. So that's stubbornly high which is a good thing of course. And you see, I mean, we've outperformed in Q4. We've outperformed in Q1. Frank LaukienChairman, CEO & President at Bruker00:53:25Q2 will be tougher because of some of the transient effects. But I hope that helps your modeling and gives you some additional insights on the timing. Rachel VatnsdalSenior Equity Research Analyst, Healthcare at JPMorgan Chase00:53:35Yes. No, that was great color. Thank you, Frank. And then just my follow-up, I wanted to dig into some of the China stimulus comments. You called out that being a little bit slower in light of the tariff situation and provinces just being slower to release those funds. Rachel VatnsdalSenior Equity Research Analyst, Healthcare at JPMorgan Chase00:53:47So can you unpack that for us a little bit more? How much stimulus revenues did you guys recognize in China in the first quarter? And then are you assuming any China stimulus revenues for the rest of the year? Thanks. Frank LaukienChairman, CEO & President at Bruker00:53:59I know it's more about orders. It was low. It was very little less than $10,000,000 certainly in Q1 as I would think most of the provinces are hanging on to the money if they have it. So it's been deferred while China is trying to figure out what's, you know, what's going on with tariffs and trade war, I assume. So it's it's yeah. Frank LaukienChairman, CEO & President at Bruker00:54:26It's been delayed, essentially. And as I said earlier, we have not baked in by now, you know, now it's May. We have not until that gets even if it got released and then turned into order as well, most of these orders then would might come in in Q3. And by that time, because there that's a lot of high big ticket, cutting edge and leading edge performance things that they order on these stimulus packages, most of that would go into '26 for our revenue. So we don't expect China stimulus to be significant in our P and L in 2025. Rachel VatnsdalSenior Equity Research Analyst, Healthcare at JPMorgan Chase00:55:11Thanks, Frank. Frank LaukienChairman, CEO & President at Bruker00:55:14You're welcome, Rachel. Operator00:55:18The next question comes from Luke Saragotte of Barclays. Go ahead, please. Luke SergottDirector - Healthcare Equity Research at Barclays Capital00:55:24Great. Thanks, guys. I just wanted to dig in a little bit on the 2Q, get some cleanup modeling. Can you just help us with the guide assumptions by the segment for BSI and BEST? What's embedded there for that low single digit constant currency growth, FX, M and A? Luke SergottDirector - Healthcare Equity Research at Barclays Capital00:55:42And then on the operating profit, I understand that the cost outs for that $90,000,000 or the mitigation efforts for that $90,000,000 turned into 45,000,000 Like how much of that 45,000,000 net are you guys looking to hit in that 2Q? Frank LaukienChairman, CEO & President at Bruker00:56:02In Q2? Gerald, that's a Luke SergottDirector - Healthcare Equity Research at Barclays Capital00:56:07long term Frank LaukienChairman, CEO & President at Bruker00:56:08Well, we get the question. Yes. I appreciate it. Probably more of that in Q3 and Q4, right? Gerald HermanExecutive VP & CFO at Bruker00:56:17Yes. Some of the mitigation actions that we've already put in place, around pricing and supply chain items are not going to fall into the second quarter for sure. It's really more about our cost management elements that we're pushing hard on for sure and that will have some modest impact in the second quarter, which is why I think we've triggered a more significant reset on the second quarter expectations. But once those elements kick in, specifically around the third Gerald HermanExecutive VP & CFO at Bruker00:56:52and Gerald HermanExecutive VP & CFO at Bruker00:56:52the fourth quarter, I think there's an expectation that our performance financial performance at the EPS line will improve sharply in the second I mean, sorry, the third and the fourth quarter and the second half of the year. Sort of the big picture. Frank LaukienChairman, CEO & President at Bruker00:57:06So as we've been already slowing hiring and using retirement and attrition and so on, we've been doing that for but some things we can actually implement relatively flexibly. I'll give you an example. In Switzerland and if needed also in Germany, in certain businesses, we can pretty quickly turn down our production capacity by almost about 20% with this short term work mechanisms where basically people end up working 20% less and they're still paid like 95%, ninety eight % because the government kicks in for up to two years. That's a great way of keeping your highly trained workforce and then ramping them back up six months or twelve months later, whatever it will be. We're already doing that. Frank LaukienChairman, CEO & President at Bruker00:57:52So we've announced that in Switzerland, for instance. So it's a very smooth and fast mechanism. And it doesn't require it doesn't cost you as much on the GAAP side in terms of restructuring and cash. And you can also implement it very quickly. But very quickly means still it's mostly going to have a Q3 and Q4 effect and maybe just a tiny bit of an effect. Frank LaukienChairman, CEO & President at Bruker00:58:13It will be effective as of Q2, but it won't move the needle financially yet in Q2. Luke SergottDirector - Healthcare Equity Research at Barclays Capital00:58:20Okay. Thanks. Then I Of Frank LaukienChairman, CEO & President at Bruker00:58:22course, things I'm sorry. There are things like discretionary spending and hiring and we're doing all of these things. Also things that you do on pricing until you put them in the price list and get a new order until you that then works out and pricing also has always a time delay. That's why these things do have effect more into the second half and then much more significant annualized effect next year. Luke SergottDirector - Healthcare Equity Research at Barclays Capital00:58:45Yes. Okay, understood. And then I guess when you talk about the other regions that are doing stimulus like South Korea and Germany and Japan, like I understand that this is more of an out year dynamic and potential tailwind, but with a little context for what those countries have done in the past from a stimulus perspective, have you done any work or have any insight there of what this could look like? Would this look like something like China stimulus in the past where you just get a huge bolus, or is this more infrastructure and more secular? Frank LaukienChairman, CEO & President at Bruker00:59:20Yeah. And I think in Korea, a number is known. And then there was also, I forget, was over three years or something like that, and it was Joe, do you have the number? 46,000,000,000 Of what currency? U. Frank LaukienChairman, CEO & President at Bruker00:59:32S. Dollars? Yes. Okay. So over three years or so, so meaningful. Frank LaukienChairman, CEO & President at Bruker00:59:37Germany is huge, but it will pay for a lot of other stuff. So it's kind of $50,000,000,000 per year over the next ten years. Some of that goes into defense, right? We do have some detection equipment that on the margin goes there. So that's a good trend for us in one of our little niches. Frank LaukienChairman, CEO & President at Bruker00:59:55A lot of it is supposed to go into innovation and technology regaining or expanding where they have a technology leadership. So there's some we're pretty optimistic that a fair that but I can't quantify because it's also as you know the new government was elected yesterday finally. And so they have some really big numbers. Some of that will build bridges. Some of that will build tanks that won't really help us although it may be good for the economy in general. Frank LaukienChairman, CEO & President at Bruker01:00:24But a lot of that probably will also go into innovation including into life science tools. So can't quantify it yet and it will almost certainly be 2026 and beyond. But could be not just the bolus, but a little bit of a longer term trend. Luke SergottDirector - Healthcare Equity Research at Barclays Capital01:00:43Great. Luke SergottDirector - Healthcare Equity Research at Barclays Capital01:00:43Thanks. Frank LaukienChairman, CEO & President at Bruker01:00:43So we'll probably get going for another five minutes or so, going over a little bit. For those who want to stay, we'll try to get to a Frank LaukienChairman, CEO & President at Bruker01:00:49few more a couple more people on questions. Frank LaukienChairman, CEO & President at Bruker01:00:54All right. We move on to the extent they're still on. Operator01:01:00Okay. The next question comes from Subbu Namdi of Guggenheim. Go ahead please. Subbu NambiManaging Director at Guggenheim Securities01:01:08Hey, guys. Good morning. Thank you for taking my question. Agreed BEST is only 10 of the revenue, but do you expect the clinical MRI SUPERCON to eventually improve for Bruker given that it's taking some time for time for AI trends to impact your revenue. One of the things is Bruker's strength is the diversified product portfolio, and therefore, not seeing strength in one of these segment when active government is down always remains a question. Subbu NambiManaging Director at Guggenheim Securities01:01:35Like your the diversified portfolio is supposed to offset all these weaknesses. That's why I'm asking about it. Frank LaukienChairman, CEO & President at Bruker01:01:43So you're talking about the best portfolio. Did I understand that correctly, Google? Subbu NambiManaging Director at Guggenheim Securities01:01:48That's right. Frank LaukienChairman, CEO & President at Bruker01:01:50Yes. Subbu NambiManaging Director at Guggenheim Securities01:01:51Yes. Frank LaukienChairman, CEO & President at Bruker01:01:51I think that's going to be a slower recovery in the MRI market. Obviously, these are other big healthcare companies that you're all familiar with. And the trends there don't fluctuate all that much. So we expect that to be a weak year for BEST. And a reasonably better year for the nearly €100,000,000 RI research instruments component. Frank LaukienChairman, CEO & President at Bruker01:02:22They just had a tough comparison in Q1 year over year. They had an incredible Q1 of last year. So the RI business I think will be not growing fast, but be steady. And the superconducting materials business this year will be weaker probably for the full year, but not as pronounced in a percentage as you would year over year as you've seen in Q1. It will be much more it will stick out less. Frank LaukienChairman, CEO & President at Bruker01:02:55All right. We have one more question for us. Thank you. Thank you, Subbu. One more question, if the next person is on there. Operator01:03:05Okay. Okay. The next question comes from Doug Schenkel of Wolfe Research. Go ahead, please. Doug SchenkelManaging Director at Wolfe Research LLC01:03:13Hey, good morning. Doug SchenkelManaging Director at Wolfe Research LLC01:03:15One question, I guess what I would call portfolio evolution and then just a follow-up on China. So portfolio evolution, some of your bigger acquisitions over the past couple of years ostensibly served to move your revenue mix away from China, and into areas outside of academic research. I'm not saying those were the primary motivations, but, you know, they they're certainly features of a lot of those deals. So China seems like a complete black box right now, and it seems like it plausibly could be structural. Academic government funding, as we've talked about extensively, is at risk globally. Doug SchenkelManaging Director at Wolfe Research LLC01:03:51So I guess what I'm wondering is when would you expect the deals you did in '23 and '24 to grow year over year on a same store sales basis? Is is is that gonna happen in '25 and '26? Are we kind of in the background starting to see the benefits of portfolio evolution? So that's that's Oh, absolutely. Frank LaukienChairman, CEO & President at Bruker01:04:10Yeah. Frank LaukienChairman, CEO & President at Bruker01:04:12Why don't why don't I And yeah. Go ahead, Zach. Doug SchenkelManaging Director at Wolfe Research LLC01:04:17Why don't we answer that and we'll come back to China in a second. Frank LaukienChairman, CEO & President at Bruker01:04:21Okay. And then we'll wrap it up. Frank LaukienChairman, CEO & President at Bruker01:04:23So yes, absolutely. The portfolio evolution is already visible. I mean, is steady and as can be. And when other things are weaker, steady high single digit growth in diagnostics, molecular microbiology is awesome. Of course, a lot of consumables, so that works. Frank LaukienChairman, CEO & President at Bruker01:04:43The automation and multiple smaller software, scientific software acquisitions, I kind of take them a little bit together because they feed each other towards the digitized lab, more automated lab. That's all working really nicely. And even as people are a little people biopharma and other industries, clean tech and fine chemicals, love to invest in that because can't either can't find the staffing or they're prepared to do it with more productivity and less hands on time. So those are all good trends. The investments of the old Berkeley Lights, which is cellular analysis, the beacon platform, as many of you know it, and about that third of spatial biology that does go into biopharma. Frank LaukienChairman, CEO & President at Bruker01:05:34Yes, they're helping us in the biopharma recovery. So that a lot of these things are already active and are offsetting some of the AGAW weakness. Without the portfolio evolution, including the pretty rapid evolution with our acquisitions in the last five, six quarters or so, this would be a tougher call and maybe we wouldn't maybe we'd go down organically this year. We think we'll still grow a little bit despite all of the headwinds. Thank you for China is hard to read. Frank LaukienChairman, CEO & President at Bruker01:06:10I agree. Doug SchenkelManaging Director at Wolfe Research LLC01:06:11Yes. My question there was just going to be and I know I'll keep it tight. If we think about even what you guys were saying a month, month and a half ago about orders related to China stimulus. You know, it it obviously sounds different today, and a lot has changed in that period. My my question is really, you know, do you think, in general, your visibility on what's going on in China and what's going to happen in China is just a lot lower than it has been for the last decade? Doug SchenkelManaging Director at Wolfe Research LLC01:06:48And do you think you have that adequately captured in guidance at this point? Frank LaukienChairman, CEO & President at Bruker01:06:54It is lower. And I hope we've got it captured because we're not built. There is stimulus plans. It's amazing when some of our executives are over there. The projects that are ready approved by the university, maybe even approved locally, just no funding yet, would be quite favorable for us in NMR, mass spec and other fields. Frank LaukienChairman, CEO & President at Bruker01:07:18But the funding doesn't get released. And I don't know whether it gets released ever or in Q2 or Q3 or Q4. And I don't think they know. However, unlike past China stimulus programs, which were sort of one or two quarter wonders, this one seems to be much more sustained. And so some of the professors or PIs of large consortia for academic medical research, they say, yeah, yeah, this will get funded. Frank LaukienChairman, CEO & President at Bruker01:07:47We just don't know whether this year or next year, and worst case in three years. But this will get funded. This is a priority. So it's more that but the timing is really there is no visibility into timing, and they don't have it either. It could be next quarter. Frank LaukienChairman, CEO & President at Bruker01:08:06It could be next year. They're all pretty confident they'll they'll get it. That's the answer. Wish I knew the timing. But that's how it works right now. Frank LaukienChairman, CEO & President at Bruker01:08:18Yeah. All right. Nine forty. So we have ten minutes over. Yeah. Operator01:08:24Okay. This concludes our question and answer session. I would like to turn the conference back over to Joe Kostka for any closing remarks. Joe KostkaDirector, Head of Investor Relations at Bruker01:08:35Thank you for joining us today. Bruker's leadership team looks forward to meeting with you at an event or speaking with you directly during the second quarter. Feel free to reach out to me to arrange any follow ups, and have a good day. Thank you. Operator01:08:51The conference has now concluded. Thank you for attending today's presentation. You may now disconnect.Read moreParticipantsExecutivesJoe KostkaDirector, Head of Investor RelationsFrank LaukienChairman, CEO & PresidentGerald HermanExecutive VP & CFOAnalystsPuneet SoudaSenior MD at Leerink PartnersMichael RyskinManaging Director at Bank of America Merrill LynchPatrick DonnellyManaging Director at CitiTycho PetersonManaging Director, Global Equities at Jefferies Financial GroupRachel VatnsdalSenior Equity Research Analyst, Healthcare at JPMorgan ChaseLuke SergottDirector - Healthcare Equity Research at Barclays CapitalSubbu NambiManaging Director at Guggenheim SecuritiesDoug SchenkelManaging Director at Wolfe Research LLCPowered by Key Takeaways Q1 performance: Revenue rose 11% year-over-year to $801.4 million (12.5% CER), with 5.1% organic growth in the Bruker Scientific Instruments segment and improved operating margins. Innovative product launches: Introduced new spatial biology, cellular analysis, NMR, microbiology, and molecular diagnostics offerings to strengthen high-value strategic portfolios and drive future differentiated growth. Macro headwinds: Anticipates a ~$100 million FY25 organic revenue impact from U.S. academic funding cuts, delayed China stimulus, and 125% China import tariffs, plus ~$90 million in operating profit headwinds before mitigation. Mitigation strategy: Implementing new pricing actions, ~$30 million in cost savings, and supply-chain/manufacturing reengineering to offset over half of FY25 headwinds and fully neutralize them by FY26. Updated FY25 outlook: Guiding $3.48–$3.55 billion in revenue (3.5%–5.5% growth) with 0%–2% organic, and non-GAAP EPS of $2.40–$2.48, implying 0%–3% reported EPS growth (5%–8% CER). A.I. generated. May contain errors.Conference Call Audio Live Call not available Earnings Conference CallBruker Q1 202500:00 / 00:00Speed:1x1.25x1.5x2xTranscript SectionsPresentationParticipants Earnings DocumentsSlide DeckPress Release(8-K)Quarterly report(10-Q) Bruker Earnings HeadlinesMichael Burry's Scion lightens up on healthcare portfolio, in Q1 movesMay 16, 2025 | msn.comBruker Corporation (BRKR) Declined Amid NIH Funding and Tariff UncertaintyMay 14, 2025 | finance.yahoo.comTrump Exec Order 14179 is wealth “gift” to good Americans?Is President Trump’s Executive Order 14179… A secret way to restore wealth for good citizens? If you’ve suffered financial hardship…Our President may have solved everything.May 22, 2025 | Paradigm Press (Ad)Investors Can Find Comfort In Bruker's (NASDAQ:BRKR) Earnings QualityMay 14, 2025 | finance.yahoo.comBruker and 10x Genomics Reach Global Settlement of Patent Litigation | BRKR Stock NewsMay 14, 2025 | gurufocus.comBruker (BRKR) and 10x Genomics Settle Patent Dispute with Cross-License Agreement | BRKR Stock NewsMay 14, 2025 | gurufocus.comSee More Bruker Headlines Get Earnings Announcements in your inboxWant to stay updated on the latest earnings announcements and upcoming reports for companies like Bruker? Sign up for Earnings360's daily newsletter to receive timely earnings updates on Bruker and other key companies, straight to your email. Email Address About BrukerBruker (NASDAQ:BRKR), together with its subsidiaries, develops, manufactures, and distributes scientific instruments, and analytical and diagnostic solutions in the United States, Europe, the Asia Pacific, and internationally. The company operates through four segments: Bruker Scientific Instruments (BSI) BioSpin, BSI CALID, BSI Nano, and Bruker Energy & Supercon Technologies. It offers life science tools, and single and multiple modality systems; life science mass spectrometry; MALDI Biotyper rapid pathogen identification platform and related test kits, DNA test strips, and fluorescence-based polymerase chain reaction technology; genotype and fluorotype molecular diagnostics kits; research, analytical, and process analysis instruments and solutions; SARS-CoV 2 testing for the diagnosis of COVID-19 infection; and Fluorotyper-SARS-CoV 2 plus kits. It also provides range of portable analytical and bioanalytical detection systems, and related products; X-ray instruments; analytical tools for electron microscopes, as well as handheld, portable, and mobile X-ray fluorescence spectrometry instruments; atomic force microscopy instrumentation; non-contact nanometer resolution solution topography; and automated X-ray metrology, automated AFM defect-detection, and photomask repair and cleaning equipment. In addition, the company offers advanced optical fluorescence microscopy instruments; products and services to support the multi-omics needs of researchers in translational research, drug, and biomarker discovery; superconducting materials, such as metallic low temperature superconductors; devices and complex tools based on metallic low temperature superconductors; and non-superconducting high technology tools, such as synchrotron and beamline instrumentation. The company was incorporated in 1991 and is headquartered in Billerica, Massachusetts.View Bruker ProfileRead more More Earnings Resources from MarketBeat Earnings Tools Today's Earnings Tomorrow's Earnings Next Week's Earnings Upcoming Earnings Calls Earnings Newsletter Earnings Call Transcripts Earnings Beats & Misses Corporate Guidance Earnings Screener Earnings By Country U.S. Earnings Reports Canadian Earnings Reports U.K. Earnings Reports Latest Articles Alibaba's Earnings Just Changed Everything for the StockCisco Stock Eyes New Highs in 2025 on AI, Earnings, UpgradesSymbotic Gets Big Earnings Lift: Is the Stock Investable Again?D-Wave Pushes Back on Short Seller Case With Strong EarningsAppLovin Surges on Earnings: What's Next for This Tech Standout?Can Shopify Stock Make a Comeback After an Earnings Sell-Off?Rocket Lab: Earnings Miss But Neutron Momentum Holds Upcoming Earnings PDD (5/27/2025)AutoZone (5/27/2025)Bank of Nova Scotia (5/27/2025)NVIDIA (5/28/2025)Synopsys (5/28/2025)Bank of Montreal (5/28/2025)Salesforce (5/28/2025)Costco Wholesale (5/29/2025)Marvell Technology (5/29/2025)Canadian Imperial Bank of Commerce (5/29/2025) Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. 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PresentationSkip to Participants Operator00:00:00Good day, and welcome to the Bruker Corporation First Quarter twenty twenty five Earnings Conference Call. All participants will be in listen only mode. After today's presentation, there will be an opportunity to ask questions. Please note this event is being recorded. I would now like to turn the conference over to Joe Director of Investor Relations. Operator00:00:46Please go ahead. Joe KostkaDirector, Head of Investor Relations at Bruker00:00:50Good morning. I would like to welcome everyone to Bruker Corporation's first quarter twenty twenty five earnings conference call. My name is Joe Koska, and I am the Director of Bruker Investor Relations. Joining me on today's call are Frank Laukien, our President and CEO and Gerald Herman, our EVP and CFO. In addition to the earnings release we issued earlier today, during today's conference call, we will be referencing a slide presentation that can be downloaded from the Events and Presentations section of Bruker's Investor Relations website. Joe KostkaDirector, Head of Investor Relations at Bruker00:01:23During today's call, we will be highlighting non GAAP financial information. Reconciliations of our non GAAP to GAAP financial measures are included in our earnings release and are posted on our website at ir.bruker.com. Before we begin, I would like to reference Bruker's Safe Harbor statement, which is shown on Slide two of the presentation. During this conference call, we will make forward looking statements regarding future events and the financial and operational performance of the company that involve risks and uncertainties, including those related to our recent acquisitions, geopolitical risks, tariffs, market demand or supply chains. The company's actual results may differ materially from such statements. Joe KostkaDirector, Head of Investor Relations at Bruker00:02:06Factors that might cause such differences include, but are not limited to, those discussed in today's earnings release and in our Form 10 ks for the period ending 12/31/2024, as updated by our other SEC filings, which are available on our website and on the SEC's website. Also, please note that the following information is based on current business conditions and to our outlook as of today, 05/07/2025. We do not intend to update our forward looking statements based on new information, future events or for other reasons, except as may be required by law, prior to the release of our second quarter twenty twenty five financial results expected in early August twenty twenty five. You should not rely on these forward looking statements as necessarily representing our views or outlook as of any date after today. We will begin today's call with Frank providing an overview of our business progress and of the expected impacts from U. Joe KostkaDirector, Head of Investor Relations at Bruker00:03:03S. Policy changes and new tariffs. Gerald will then cover the financials for the first quarter of twenty twenty five in more detail and share our updated full year 2025 financial outlook. Now I'd like to turn the call over to Bruker's CEO, Frank Laukien. Frank LaukienChairman, CEO & President at Bruker00:03:21Thanks, Joe. Good morning, everyone, and thank you for joining us on today's first quarter twenty twenty five earnings call. Bruker had a solid start to 2025 with double digit reported and constant exchange rate or CER revenue growth. We also had 5.1% organic revenue growth in our Bruker Scientific Instruments segment and better operating margin performance than expected. In short, our teams executed very well under significant uncertainties in key markets. Frank LaukienChairman, CEO & President at Bruker00:03:53In the first quarter and in April at the important AGBT, E and C, ESKMET and AACR conferences at the Alphabet Soup, we launched a number of very innovative performance leading new products in spatial biology, cellular analysis, NMR, microbiology and molecular diagnostics, all strengthening our high value offerings in key areas of our strategic focus. I'll cover several of these important new products in a few moments, but the key message here is that in times of funding uncertainties and in particularly it is particularly important to enable our customers with unique and highly relevant new research and clinical capabilities. We also expect these meaningful post genomic innovations to drive continued higher revenue CAGR differentiation for Bruker beyond the present AKAgov headwinds in The U. S. And China. Frank LaukienChairman, CEO & President at Bruker00:04:53Let's begin on Slide four. With the performance of the business in Q1 twenty twenty five, then I'll walk you through the impact of recent U. S. Policy changes and the new tariff regime, how we anticipate it will impact Bruker and how we intend to mitigate the resulting headwinds to our margins slightly more than half in 2025 and then completely by 2026. On Q1 twenty twenty five performance, we delivered a stronger than expected first quarter. Frank LaukienChairman, CEO & President at Bruker00:05:23Bruker's Q1 '20 '20 '5 reported revenues increased 11% year over year to $801,400,000 above our preannounced range of $795,000,000 to $800,000,000 and significantly above prior expectations. Our constant exchange rate CER revenue growth was 12.5% year over year, including organic growth of 2.9% with, as I said earlier, a reasonably strong 5.1% organic growth delivered by our BSI segment and a 9.6% contribution to revenue growth from acquisitions. If you recall, we did some of our larger acquisitions last year in the second quarter. Notably, performance in the biopharma end markets strengthened in the quarter and grew in the mid single digits percentage. Our first quarter twenty twenty five non GAAP operating margin was 12.7%, which was down year over year due to the expected M and A dilution from the strategic acquisitions I just mentioned that we completed in Q2 twenty twenty four. Frank LaukienChairman, CEO & President at Bruker00:06:32However, underneath we again posted strong organic operating profit margin expansion of about 100 basis points year over year in the quarter. Our first quarter twenty twenty five diluted non GAAP EPS was $0.47 down from $0.53 in Q1 twenty twenty four due to expected and more recent FX currency headwinds. Please turn to slides five and six, where we highlight the first quarter CER performance of our three Scientific Instruments groups and of our BEST segment year over year. In Q1, BioSpin revenue was $2.00 $8,000,000 with mid teens percentage CER growth. BioSpin growth was driven by strong ACCA gov revenue including an ultra high field NMR system in The UK, by industrial research and food safety markets and a strengthening biopharma environment, as well as strong contributions from preclinical imaging and lab automation, the new ChemSpeed business. Frank LaukienChairman, CEO & President at Bruker00:07:38In Q1, our CALID group had revenue of €280,000,000 with mid-20s percentage CER growth. CALID growth was led, as you might expect, by microbiology and infection diagnostics, including the acquired ElliTech molecular diagnostics business as well as double digit plus growth in life science mass spectrometry driven by strength in the timsTOF platform. CALID saw robust growth in Europe and The Americas and strength in clinical, industrial and biopharma applications, while agarGalp performance was moderate. Turning to slide six. In Q1, Bruker Nano revenue was $257,000,000 with CER revenue growth up high single digits percentage. Frank LaukienChairman, CEO & President at Bruker00:08:30Growth was supported by inorganic revenue growth from NanoString, which was not yet included in Q1 of twenty twenty four, the year over year comparison. Strength in APAC ex China, Biopharma and agagav markets were partially offset by softness in Europe and China as well as in X-ray and nanoanalysis tools. Finally, first quarter BEST CER revenues declined in the high teens percentage net of intercompany eliminations as our Research Instruments business saw weaker performance in the quarter. They had a very strong prior year comparison. And that also was combined with continued softness in the superconductor market for clinical MRI. Frank LaukienChairman, CEO & President at Bruker00:09:18Moving to slide seven, we highlight the recent innovations underscoring Bruker's leading commitment to advancing spatial biology announced first at AGBT and then expanded further at AACR in Chicago in late April. There's a lot of information on slide seven. Don't worry, I won't read it all. But it gives you a highlight it gives you an idea about the breadth and depth and best in class performance of each platform, each significantly enhanced in terms of content or sensitivity or throughput and of course the completely unique paintscape. Maybe one theme that comes here throughout is that Spatial is going multi omics. Frank LaukienChairman, CEO & President at Bruker00:10:07Both our GeoMx platform now allows HyFlex transcriptomics, of course, that's what we're known for, but also tissue proteomics. And that's also, by the way, true for our non spatial nCounter system that you may recall from the NanoString days. CosMiX with the old transcriptome panel now that is ready for orders where we can really get 19,000 protein encoding genes at the transcriptome level is an unmatched research tool. And importantly, we've increased our detection efficiency by a factor of 2x, one of the areas that was that the customers were waiting for. Too much detail, let me move on to Slide eight. Frank LaukienChairman, CEO & President at Bruker00:10:56Eight is an important acquisition, gets us into a different branch of Diagnostics. This is not microbiology, infectious disease and it very much fits with our triple quadrupole mass spec strategy, which of course is very differentiated with our particular claim to fame and focus to chromatography free or chrome free point of need mass spectrometry using triple quad targeted technology. This gives us the crucial assays and kits and consumables business. Recife is based in Munich, been in business for over forty years. Revenue is a little greater than €15,000,000 very profitable. Frank LaukienChairman, CEO & President at Bruker00:11:37And for the European market, it gives us the therapeutic drug monitoring and other kits for IBD and other things that we don't need to go into detail. This combination kits, assays, contents with a diagnostic focus for therapeutic drug monitoring and also by the way eventually drugs of abuse because it cannot be so fast and inexpensive with the DART chrome free approach is actually strategically quite exciting to us. And we think these two instruments plus assays and diagnostics coming together is a nice is an important additional growth trajectory for the company. But we know you want to hear about the macro and ACOGov, so let's go into it. Let me make sure I'm on the right slide. Frank LaukienChairman, CEO & President at Bruker00:12:24Yes, I will now review our assessment and anticipated impact from U. S. Policy changes regarding federal funding for academic research and the current tariff regime on Bruker for the remainder of 2025. Moreover, I will provide an overview of our additional cost initiatives, new pricing actions and already ongoing and now accelerating supply network reengineering to partially mitigate at least half of the new headwinds in this year fiscal twenty twenty five and then more fully in fiscal twenty twenty six. So here we go. Frank LaukienChairman, CEO & President at Bruker00:13:03Our initial estimates are that U. S. Policy changes to federal research funding, lower China stimulus funding release and some temporary revenue impact of new China tariffs on revenue will amount to an approximately €100,000,000 gross headwind to our organic fiscal year twenty twenty five revenues before some mitigation. You cannot mitigate that much on the revenue side, but a little bit. Anyway, this €100,000,000 fiscal year 20 20 5 revenue headwind is broken into three buckets. Frank LaukienChairman, CEO & President at Bruker00:13:41First, and that's a smaller and transient one, some fiscal year twenty twenty five China revenues that were to be shipped from The U. S. May be delayed are delayed by customers or may be partially canceled due to the current 125% Chinese import tariffs on U. S. Goods. Frank LaukienChairman, CEO & President at Bruker00:14:00We're working with our customers to partially mitigate this impact with supply chain alternatives, tariff extensions or delivery delays with the largest transient impact now expected in the second quarter of twenty twenty five. Then second, the strongest, but by far the strongest revenue headwind this year not surprisingly is related to U. S. Aga Gov markets as a result of research funding policy changes. For Bruker, we now expect U. Frank LaukienChairman, CEO & President at Bruker00:14:31S. Aga gov revenue to be down 20% to 25% for this year. U. S. Agagav in fiscal year twenty twenty four had grown to about 10% of overall Bruker revenues. Frank LaukienChairman, CEO & President at Bruker00:14:45And in the updated guidance, we assume that the current academic funding uncertainty continues even though we acknowledge there's some potential upside in the second half of twenty twenty five if NIH and NSF and DOE R and D grants begin to flow again without further delays. Anyway, we have not baked those in. So hopefully this is a floor. Finally, we do not think that the President's initial budget request for NIH and NSF will be passed by Congress as is without an improvement. We expect it to be down, but not as much as the opening bid. Frank LaukienChairman, CEO & President at Bruker00:15:22Third, a headwind related to anticipated China AGAGRAPH revenue as funding of the stimulus programs China has been slow to be released by the provinces. Many shovel readying projects, lot of them with our instrumentation, high end Accagov, but slow to release as they're probably watching tariff and trade wars. This may improve throughout 2025, but at the moment timing and amounts are uncertain. So there are a number of moving parts that could provide additional upside such as release of China stimulus funding, German and South Korean stimulus funding, European defense and security investments, we see some of that, and further semiconductor metrology strength due to the AI machine learning trends, which we which are very profitable for us. So these factors could add upside, but we have not built them into our guide assumptions, hoping to provide a floor for 2025 with upside in any case more likely to benefit fiscal twenty twenty six. Frank LaukienChairman, CEO & President at Bruker00:16:30We also note that uncertainty around potential U. S. Tariffs on pharma products could slow the encouraging recovery that we have seen in drug discovery and development markets in the last two quarters. And again, we have tried to take that into account in our guidance. So that was the revenue piece. Frank LaukienChairman, CEO & President at Bruker00:16:47Let's move to operating profit or margins. So with respect to 25,000,000 operating profit, the gross headwinds before our mitigation actions are pretty meaningful. So first of all, the roughly $100,000,000 of produced organic revenue previously noted is expected to lead to about a $50,000,000 reduction in $25,000,000 operating profit. Moreover, Bruker imports about 75% of our U. S. Frank LaukienChairman, CEO & President at Bruker00:17:14Product revenue, obviously not the services revenue, there's another piece to it. But of our product revenue, 75% is imported largely from the European Union and Switzerland, but also from Israel and Malaysia. The current U. S. Import tariff rate of 10% from those countries would result in an additional headwind of at most of about $40,000,000 to operating profit for the remainder of $2,025,000,000 again before our ongoing mitigation actions. Frank LaukienChairman, CEO & President at Bruker00:17:44That's a gross headwind. U. S. Tariffs on imports from China for Bruker have a negligible effect on Bruker excluding some secondary supply chain inflationary effects, but we basically don't import any products from China. So in total, we therefore estimate gross headwinds for our twenty five percent operating profit primarily from U. Frank LaukienChairman, CEO & President at Bruker00:18:08S. Aga gov disruption and new tariffs to be about $90,000,000 altogether before our mitigation actions. Now deploying our Bruker management process and strong leadership team that as you've seen has been really excellent executing very well not only this year, but for many years. We have already taken and are taking numerous actions to offset more than half of these margin headwinds this year with the remainder expected to be fully effective next year in 2026. Our mitigation actions include new pricing actions, additional cost cutting initiatives and supply network and manufacturing reengineering. Frank LaukienChairman, CEO & President at Bruker00:18:50We estimate these mitigation measures will offset slightly more than half of the operating profit headwind for 2025. We then expect to fully offset these headwinds through price, cost and supply network and manufacturing reengineering by 2026. Fortunately, we're a very international company with a lot of flexibility, but it takes a little bit of time. Anyway, factoring in U. S. Frank LaukienChairman, CEO & President at Bruker00:19:15Agagav and tariff headwinds as well as the recent weakening of the U. S. Dollar, a significant effect as well as our mitigation actions and taking it all into our updated fiscal year twenty twenty five non GAAP EPS projections leads us to a new guidance range for EPS of $2.4 to $2.48 So in summary, Bruker delivered strong CER growth and organic operating margin expansion in the first quarter of twenty twenty five. We're experiencing new headwinds as a result of ACAGOL policy changes and tariffs. As always, we remain agile in responding to the evolving dynamics. Frank LaukienChairman, CEO & President at Bruker00:19:56Our management process is navigating us through these headwinds in 2025 and setting us up for resuming margin expansion and strong EPS growth in 2026 and beyond. So with that, let me turn the call over to Gerald, our CFO, who will review our financial performance in more detail and provide further color on our updated outlook for 2025. Gerald, go ahead please. Gerald HermanExecutive VP & CFO at Bruker00:20:21Thank you, Frank, and thank you everyone for joining us today. Pleased to provide more detail on Bruker's first quarter twenty twenty five financial performance, starting on Slide 10. In the first quarter of twenty twenty five, we had another quarter of excellent execution, delivering a strong first quarter above our earlier expectations and the color provided to the investor community. In the first quarter of twenty twenty five, Bruker's reported revenue increased 11% to $801,400,000 which reflects an organic revenue increase of 2.9% year over year. Acquisitions added 9.6% to our top line, while foreign exchange was a 1.5% headwind, resulting in constant exchange rate revenue growth of 12.5% year over year. Gerald HermanExecutive VP & CFO at Bruker00:21:08Geographically and on a year over year organic basis in the first quarter of twenty twenty five, our Americas revenue declined in the low single digits percentage. European revenue grew in the mid single digits percentage, while Asia Pacific revenue grew in the low single digits percentage despite a 10% decline in China. For our EMEA region, revenue was up mid teens percentage. We delivered strong BSI organic revenue growth in the first quarter of twenty twenty five at 5.1%, driven by strength in our bBio and CALID groups. BSI Systems grew in the mid single digit range and BSI Aftermarket revenue grew in the high single digit range organically year over year. Gerald HermanExecutive VP & CFO at Bruker00:21:55Our order book performance in our BSI segment was down slightly compared to the prior year first quarter with softer academic government orders in The U. S. And in China. Non GAAP gross margin increased 10 basis points to 51.3%. In Q1 twenty twenty five, non GAAP operating margin was 12.7, which included 100 basis points of organic operating margin expansion on better mix and cost control, more than offset by planned M and A dilution as Q1 twenty twenty four did not include two of our largest strategic acquisitions that closed in the second quarter of twenty twenty four. Gerald HermanExecutive VP & CFO at Bruker00:22:38On a non GAAP basis, Q1 of twenty twenty five diluted EPS was $0.47 down 11.3% from the $0.53 we posted in the first quarter of twenty twenty four, which did not yet include our key acquisitions last year. Our non GAAP effective tax rate was 27.7% compared to 26.7% in the first quarter of twenty twenty four, with the increase driven mostly by an unfavorable discrete item. On a GAAP basis, we reported diluted EPS of zero one one dollars compared to $0.35 in the first quarter twenty twenty four. Weighted average diluted shares outstanding in the first quarter twenty twenty five were 151,900,000.0, an increase of 6,000,000 shares or 4.1% from the first quarter of twenty twenty four, resulting from our follow on equity offering in May of twenty twenty four. Turning now to slide 11. Gerald HermanExecutive VP & CFO at Bruker00:23:36We generated $65,000,000 of operating cash flow in the first quarter of twenty twenty five. Our capital expenditure investments were $26,000,000 resulting in free cash flow of $39,000,000 in the first quarter of twenty twenty five. This reflects an improvement in free cash flow of about $39,000,000 over the first quarter of twenty twenty four, driven by better working capital performance in the quarter. We finished the first quarter with cash, cash equivalent and short term investments of approximately $184,000,000 During the first quarter, we used cash to fund capital expenditures, select Project Accelerate two point zero initiatives and debt repayments. Turning now to slide 13. Gerald HermanExecutive VP & CFO at Bruker00:24:20As Frank noted earlier, we're updating our fiscal year twenty twenty five outlook to reflect a strong first quarter and the impact of recent policy changes and tariffs. We now expect reported revenues of 3,480,000,000.00 to $3,550,000,000 representing reported growth of 3.5% to 5.5%. This guidance assumes organic revenue growth of 0% to 2%, an estimated tailwind from foreign exchange of about 1% and acquisitions to contribute approximately 2.5% to revenue growth. This implies constant exchange rates ER revenue growth of 2.5 to 4.5% all year over year. The revenue guidance includes an organic revenue gross headwind of approximately $100,000,000 from recent policy changes and tariffs, partially offset by pricing and other mitigation actions of about $20,000,000 for a net headwind of about $80,000,000 We now expect our fiscal year twenty twenty five operating margin to be roughly flat year over year with organic improvement of greater than 70 basis points including mitigation actions to be roughly offset by headwinds from M and A and foreign exchange. Gerald HermanExecutive VP & CFO at Bruker00:25:41Recent policy changes, academic government market weakness in The U. S. And China, together with the current level of U. S. And China import tariffs are assumed to be a $90,000,000 gross headwind to operating profit in fiscal year twenty twenty five. Gerald HermanExecutive VP & CFO at Bruker00:25:58We anticipate over half of this impact to be offset through our mitigation actions, including pricing about £10,000,000 cost management about £30,000,000 and supply chain reengineering about 10,000,000 already in fiscal year twenty twenty five. On the bottom line, we're now guiding to non GAAP EPS for 2025 in a range of $2.4 to $2.48 This translates to roughly non GAAP EPS growth of 0% to 3% compared to 2024. Given the recent weakening of the U. S. Dollar against major currencies, foreign exchange is now a 5% headwind to our non GAAP EPS, implying constant exchange rate non GAAP EPS growth of 5% to 8% for fiscal year twenty twenty five. Gerald HermanExecutive VP & CFO at Bruker00:26:48Other guidance assumptions are listed on the slide. Please note our fiscal year twenty twenty five ranges have been updated for foreign currency rates and tariff rates as of 04/30/2025. While there are other policy and macroeconomic risks that could further impact our fiscal year twenty twenty five financial performance, with this updated guidance, we hope to have established a floor based on current headwinds and our robust mitigation actions. Given the lower base years of 2024 and 2025, it's now become clear that our previously communicated medium term outlook targets are not likely to be realized under our originally planned cadence. We intend to provide updated medium term outlook targets when we have a clear line of sight on U. Gerald HermanExecutive VP & CFO at Bruker00:27:36S. Federal research policy and funding and stabilized tariffs. Fundamentally, we remain optimistic that we've transformed Bruker's portfolio for above market revenue growth, rapid margin expansion towards the mid-twenty percent operating margins and mid high teens EPS growth once new headwinds abate. Finally, to add color on the second quarter of twenty twenty five, given softer U. S. Gerald HermanExecutive VP & CFO at Bruker00:28:05And China academic government market conditions and some U. S. Produced China revenue likely delayed from the second quarter, we expect our second quarter twenty twenty five organic revenue to decline in the low single digits, while constant exchange rate revenue is expected to increase in the low single digits percentage both year over year. In the second quarter of twenty twenty five, we also expect to see a transient year over year decrease in non GAAP operating margin and non GAAP EPS performance, with significant improvements in both metrics expected in the second half of this year. To wrap up, Bruker delivered a solid BSI organic revenue growth and organic operating margin expansion in the first quarter twenty twenty five under uncertain conditions. Gerald HermanExecutive VP & CFO at Bruker00:28:57Moving forward, we remain confident in our ability to continue to execute well under a challenging environment. And with that, I'd like to turn the call over to Joe. Thank you very much. Joe KostkaDirector, Head of Investor Relations at Bruker00:29:09Thanks, Gerald. I'd now like to turn the call over to the operator to begin the Q and A portion of the call. Operator00:29:24We will now begin the question and answer session. Our first question comes from Puneet Souda of Leerink Partners. Go ahead please. Puneet SoudaSenior MD at Leerink Partners00:30:09Frank. Thanks for the questions here and thanks for all the details on the tariffs for quantifying that. Could you elaborate if there was any pull forward in the quarter because of the tariffs worries or any other worries in the market that the customers might have had? And are you baking any impact from that as a result of that pull forward? And then in China, I appreciate you mentioned cancellations, but are you seeing any cancellations in The U. Puneet SoudaSenior MD at Leerink Partners00:30:42S. Or European markets, specifically maybe around UHF gigahertz magnet? I didn't hear guidance on that for the year. Frank LaukienChairman, CEO & President at Bruker00:30:53Okay, Puneet. Thank you. So there really wasn't any pull forward that's being talked about due to tariffs or AGA gap. We didn't see that. However, we acknowledge that The U. Frank LaukienChairman, CEO & President at Bruker00:31:07K. One Point Two gigahertz system that we had expected for Q2, It just technically, it just went in easily and so it got in Q1. That wasn't a pull forward. That was just a really smooth installation. So that helped Q1 a little bit and of course I wouldn't call it a pull forward. Frank LaukienChairman, CEO & President at Bruker00:31:30It was not a market driven pull forward. To cancellations, we don't really see any China cancellations yet. Customers who don't have the budget to pay the extra 125% for which they according to the terms would be mostly we think would be on them, but they just don't they presently right now are a little bit in this holding pattern. Hey, don't ship yet. We can't accept it because we can't pay the import duties. Frank LaukienChairman, CEO & President at Bruker00:32:01It's not a big effect, but of course in Q2 it's going to be noticeable as Gerald explained. We do not see any cancellations. We see lots of uncertainties and delays in The U. S. And AGAGOV. Frank LaukienChairman, CEO & President at Bruker00:32:13We haven't seen any cancellations because of that. No cancellations yet in China, but delays. And in some cases, we are also simply rerouting and maybe building some of these systems in Europe or Malaysia. So hopefully, we can mitigate, but sort of typically with a quarter's delay. Puneet SoudaSenior MD at Leerink Partners00:32:37That's helpful. Frank LaukienChairman, CEO & President at Bruker00:32:38Hopefully, are two questions. Yes. Puneet SoudaSenior MD at Leerink Partners00:32:40Yes. Puneet SoudaSenior MD at Leerink Partners00:32:41Thank you. And then when we think about the offsets, obviously, a lot of challenges in the market today. But when we think about the offsets, the AI chips, onshoring of that, the funding initiatives in Germany, maybe lower interest rates. Can you walk us through how are you thinking about some of those offsets potentially sort of mitigating the impact maybe into the second half? Frank LaukienChairman, CEO & President at Bruker00:33:13Yes. In terms of orders, they may I mean AI remains very strong in our tools. I mean of course, there's more important partners. But without us, the AI revolution also wouldn't work, right? TMSC absolutely needs our tools. Frank LaukienChairman, CEO & President at Bruker00:33:30I think they are single largest customer in the world at this point. Of course, they're doing a lot of work both in Japan and in The U. S. They're upgrading and investing in Taiwan. So that remains strong and has remained strong. Frank LaukienChairman, CEO & President at Bruker00:33:43In fact, for AI driven bookings in Q1 were quite strong. So that's strong. And a lot of the delivery times for these things are longer. When their fab is ready middle of next year, you can't really ship it earlier. German and Korean and similar stimulus funding or European defense fund spending. Frank LaukienChairman, CEO & President at Bruker00:34:04The timelines, these are all good trends. Some of them are beginning to turn into orders. Some of them just are very encouraging in Germany, would say. That's nearly 10% of our revenue in typical years. But I don't think they'll make much of a difference anymore in revenue and in our P and L this year. Frank LaukienChairman, CEO & President at Bruker00:34:25They are, however, welcome tailwinds for 'twenty six and even into 'twenty seven, 'twenty eight. So AI will help us also this year. Although if I take an order today, it's probably for next year, but I have orders that I can ship this year and that continues to be strong demand. And yes, the onshoring in Japan, in The U. S, also in Europe plays a role, but that's also very significant continued investments by the leading technologically leading companies in Taiwan and in Korea. Frank LaukienChairman, CEO & President at Bruker00:35:01So that's actually quite good. Puneet SoudaSenior MD at Leerink Partners00:35:05Helpful. I'll hop back into the queue. Thank you. Frank LaukienChairman, CEO & President at Bruker00:35:08Thank you, Puneet. Operator00:35:12The next question comes from Michael Ryskin of BoA. Go ahead please. Michael RyskinManaging Director at Bank of America Merrill Lynch00:35:18Great. Thanks for taking the question. Frank, I want to talk about a comment you made towards the end of the prepared remarks in terms of medium term guide being a little bit unrealistic in the current environment. So if we just focus on The U. S. Michael RyskinManaging Director at Bank of America Merrill Lynch00:35:30Policy changes, you mentioned Trump's initial proposal is 40% cut. You don't think that will happen because Congress will offset. But let's say it's 20%, twenty five % cut to next year's budget, to pick a number similar to what your assumption is for this year. How does Bruker offset that next year? Could you talk about how you would respond? Michael RyskinManaging Director at Bank of America Merrill Lynch00:35:51What different levers you are? How we should think about possible ways to get around that, whether it's pharma biotech, whether it's Puneet just asked on AI and some of that, some of the more industrial tech parts of the business. Just sort of what steps would you take to offset that U. S. A and G cut that would be a little bit more medium term? Frank LaukienChairman, CEO & President at Bruker00:36:13Yes. No, you listed most of them. So I'll as you've seen our twenty four mid-twenty four medium term outlook, '24, '20 '5 to '2 base years have obviously changed. That's what we're talking about. So therefore, we'll look we are very committed to resuming very significant margin expansion this year. Frank LaukienChairman, CEO & President at Bruker00:36:38All that we had a lot more than the 140 bps lined up, and we're hoping to do much better than that. Turns out this year, we're kind of moving sideways because we're using all of these improvements plus new cost and pricing and supply chain actions to just deal with the headwinds this year. So but assuming no new, new headwinds by 2026 and beyond, think this operating model, operational excellence integration that all still works, but it kind of takes with a one year shift because this year we're playing defense quite honestly. Right. I think all these trends that you did mention, biopharma has been picking up nicely. Frank LaukienChairman, CEO & President at Bruker00:37:19Our tools for biopharma, including those from spatial biology and beacon cellular analysis, You've seen we've not just done cost cuts, we've done incredible fantastic fast product development to resume growth in these businesses when the headwinds abate, right? We're doing very well with AI. Then we just discussed that with Puneet and you asked about it, that's doing well. European security and defense spending, European investment quite honestly, infusion research, other clean energy projects are all helping us. So there's a lot of good growth drivers that are a little bit overshadowed this year, but that I think will play a bigger role next year. Frank LaukienChairman, CEO & President at Bruker00:38:02There's also some transient effects that we've explained a little bit that just go away. Your estimate that I don't know where NIH and NSF funding comes out once it gets through Congress. I'm pretty sure it's not the opening bid. Would it be but I think it will be down. I agree with you, it will be down. Frank LaukienChairman, CEO & President at Bruker00:38:20Maybe just not as deeply as proposed by the White House initially. But there are many other. I mean, Germany is not only looking at defense, they're really looking at significant R and D and innovation infrastructure and tools investments and other the weakness of the America academic system. There will be other countries that try to, well, quite honestly exploit that a little bit and say, oh, great, we can get some researchers. Let's give them a start up budget. Frank LaukienChairman, CEO & President at Bruker00:38:49So you see some of that dynamics. There's a lot of growth drivers that just most we're not baking them in this year even if they help us a little bit in the second half. Mostly I think it will be on orders And we're just trying to set ourselves up for giving a baseline for 25,000,000 moving sideways a little bit with some organic growth and a little bit of EPS growth. Actually EPS growth excluding currency is reasonable for us this year and what we're projecting and then really fully resuming fast margin expansion EPS growth etcetera next year. Michael RyskinManaging Director at Bank of America Merrill Lynch00:39:25Okay. That's all really helpful. Michael RyskinManaging Director at Bank of America Merrill Lynch00:39:27And then Gerald if I could squeeze in a follow-up for you. You mentioned the comments in your prepared remarks about order book and BSI down year over year on ANGI in U. S. And China. Obviously, makes sense given what's going on there. Michael RyskinManaging Director at Bank of America Merrill Lynch00:39:39Anyway, you could quantify that either via book to bill or just an order growth number? And then could touch on your backlog, your existing backlog ability to offset maybe a lower order book in 1Q, 2Q this year, just sort Michael RyskinManaging Director at Bank of America Merrill Lynch00:39:56of what that buffer gives you? Michael RyskinManaging Director at Bank of America Merrill Lynch00:39:58Thanks. Gerald HermanExecutive VP & CFO at Bruker00:40:01With respect to the order performance in the first quarter, was actually just slightly under the first quarter of twenty twenty four. The general composition of that was while we did see a slightly weaker performance in academic and government research sectors in both China and The U. S, we saw strength actually in biopharma and in some of the industrial markets, including semi of course. So I think generally speaking, right now, we are reasonably well positioned on the order book in order for us to continue to these orders, of course, benefit as you march into the second half of twenty twenty five and further into 2026. So I think generally speaking, our general position is we're feeling pretty good about that. Gerald HermanExecutive VP & CFO at Bruker00:40:49I would say on the backlog, we are still at seven months on a backlog level. So we do have some remaining backlog to be able to pull on in some of these quarters. We didn't see much decrease in the backlog drawdown level in the first quarter. So we'll see how this all plays out over the next couple of quarters. But fundamentally, we still have quite a bit of backlog to be able to pull on. Gerald HermanExecutive VP & CFO at Bruker00:41:15So I think that's the high level view, Brian. Frank LaukienChairman, CEO & President at Bruker00:41:18And BSI book to bill just below 0.95, not great, a little weaker in March as you would have expected, which is fits the overall pictures as expected, not great, not bad. Great. Thanks a lot guys. I'll leave it there. Appreciate it. Gerald HermanExecutive VP & CFO at Bruker00:41:36Sure. Operator00:41:40The next question comes from Patrick Donnelly of Citi. Go ahead please. Patrick DonnellyManaging Director at Citi00:41:47Hey, good morning guys. Maybe one more on the tariff side, encouraging to hear you guys offsetting that for 2026. Can you just talk through it sounds like pricing, cost initiatives, moving to manufacturing around, supply chain management. Can you just talk through, I guess, the new pricing assumptions, what you're doing on the manufacturing side? Just want to talk through that confidence level of offsetting it into 2026 and preserving that number and again kind of moving into 2026 with a clean slate on the tariff offsets. Patrick DonnellyManaging Director at Citi00:42:16If you could just talk through pricing, manufacturing cost initiatives that you're using to offset it. Frank LaukienChairman, CEO & President at Bruker00:42:23Yes. Patrick, thank you. Good questions. So pricing, yes, we're taking some U. S. Frank LaukienChairman, CEO & President at Bruker00:42:31But also some worldwide additional pricing action. I think for competitive reasons, we'd like to not go into that. It's not across the board, right? You kind of do it in a way that's smart and like all other companies. In terms of supply chain, yes, certainly the usual things that you do as an international company, I mean, are some products that you can do the final assembly and systems test. Frank LaukienChairman, CEO & President at Bruker00:42:59We can do it in The U. S. Or we can do it in Europe or we can do it in our Malaysia, Penang Malaysia major manufacturing centers. And we're exploring all of that and looking at all of that. Vice versa, we used to do X-ray and mass spec and NMR final assembly and systems test in The U. Frank LaukienChairman, CEO & President at Bruker00:43:20S. We're talking to third party trusted contract manufacturers that are international that we're already using either in Malaysia or in Europe quite honestly. And they have one of them has a facility here in New Hampshire and others have other U. S. Facilities about onshoring parts of our production even. Frank LaukienChairman, CEO & President at Bruker00:43:44And for that, of course, we also need a little bit more visibility about where transatlantic tariffs or respect to Israel and Malaysia end up. Right now, we assume existing tariff rates, which may not be a bad assumption for where things end up, but then again nobody is entirely sure. And yes, cost actions, think, Gerald mentioned those. The additional cost actions, We expect this year to amount to about $30,000,000 so pretty aggressive. And by the way, we didn't wait for that. Frank LaukienChairman, CEO & President at Bruker00:44:17That has started actually that started some of it has started right at the beginning of the year because we wanted to overperform our initial guidance. And then more of that has been significantly accelerated as more clouds moved in. And so yes. And so here, that's the cost actions are significant. The supply chain, you don't see such a big number, 10,000,000 this year, but that has a little bit more of a delayed effect. Frank LaukienChairman, CEO & President at Bruker00:44:48That will be a much bigger effect next year. Patrick DonnellyManaging Director at Citi00:44:53Okay. That's helpful. And then maybe a bit of a follow-up on Mike's question there. When you think about the academic market, Frank, I know you're talking about academic government, think, down 20%, twenty five % this year. I guess when you look forward, Gerald mentioned that mid- high teens earnings once these headwinds are absorbed, are you thinking that the academic market one of the big questions we get is, is this structural for the next few years, right, where this declines every year for the next few years? Patrick DonnellyManaging Director at Citi00:45:19Or is it you rebase this year and then have opportunity for that piece to grow? How do you think about the academic government exposure here? And is this, again, with the new administration in office, is this structural until things change on that front over the next few years? Frank LaukienChairman, CEO & President at Bruker00:45:35Yes. We still assume that U. S. Aga gov will be weak on the weaker side next year. Of course, we don't have straight visibility about some of the budget negotiations. Frank LaukienChairman, CEO & President at Bruker00:45:47I know they'll be negotiated, but I don't think that Congress will then say, hey, never mind, Mr. President, we're going to have an NIH budget increase. But probably hopefully a lesser decrease. Other things, of course, I mean, ACA gov 75% of the ACA gov market for us worldwide is outside The U. S. Frank LaukienChairman, CEO & President at Bruker00:46:13That's doing well. There's even some stimulus funding. There is some that's actually one of the better pieces of our demand. In The U. S, we also expect it to be weak, but probably growing compared to this year's more disrupted aga gov market, where there's also been the delays and the arguments over what's allowable overhead and indirect cost and then certain universities being in political fights with and some of them are big, right? Frank LaukienChairman, CEO & President at Bruker00:46:44Some of them that's not insignificant. So I think some of that we believe will be somewhat temporary, although temporary not one or two quarters, but for this year. And we still expect some weakness next year, although probably growth year over year compared to this year in The U. S. Like I got. Frank LaukienChairman, CEO & President at Bruker00:47:04Right? Understood. Thanks. Thank you, Patrick. Operator00:47:11The next question comes from Tycho Peterson of Jefferies. Go ahead please. Tycho PetersonManaging Director, Global Equities at Jefferies Financial Group00:47:17Hey. Thanks. Frank, I wanna dig into your pharma comments. You mentioned strengthening biopharma a few times. So did it get better as the quarter progressed? Tycho PetersonManaging Director, Global Equities at Jefferies Financial Group00:47:25Anything you can say in April? Is that mostly timsTOF? And in your guidance you alluded to maybe baking in some pharma slowdown. Maybe just talk about the gives and takes. Frank LaukienChairman, CEO & President at Bruker00:47:37Yes. Biopharma as you know we're partly in the late regulated but mostly in the drug discovery and development. Yes, biopharma has been increasing from a weak base last year or before that even. Biopharma has been had trended very nicely for us in Q4 already and in Q1. I don't really for us because we're not primarily consumables April, I can't comment. Frank LaukienChairman, CEO & President at Bruker00:48:02Taking that in and knowing that there's a threat of biopharma tariffs, we have put in a moderated recovery, a dampened recovery in biopharma, but not it falling back into a hole as it was maybe a year ago or so. TimsTOF NMR, but also a little bit of spatial, of course, our cellular analysis, beacon tools now that we have the new benchtop discovery system. There is a we're having more and more we're not a one trick pony or a two trick pony in biopharma anymore. So there's a lot of tools, including some process analytical tools and things like that, ProcessRama and some of the automation things from our ChemSpeed acquisition, some of the software that all supports efficiency and productivity and investments in pharma towards the digital lab and maybe eventually the lights out lab and things like that. So we have a bunch of things that are driving It's not only a one or two product story anymore, and that's all been reasonably healthy. Frank LaukienChairman, CEO & President at Bruker00:49:13Actually, it's been quite healthy the last two quarters. Tycho PetersonManaging Director, Global Equities at Jefferies Financial Group00:49:17That's helpful. And then follow-up on m and a. You know, you're adding the the Rossipee deal just over 15,000,000 or so in revenues, but you're not really changing your contributions here. It was two to three before, and now it's two and a half. So maybe just talk a little bit about, you know, what what the offsets are, on m and a. Tycho PetersonManaging Director, Global Equities at Jefferies Financial Group00:49:33And are you kind of more optimistic on revenue synergies from some of the deals, maybe just a scorecard now that we're kind of a year into Frank LaukienChairman, CEO & President at Bruker00:49:43ChemSpeed is doing great, better than expected with its automation demand in pharma So very happy with that. Elitech, my god, the most predictable business ever and they're doing well. And in fact, they did well again in Q1. So that's a good space and they're doing a little better than our acquisition model. Frank LaukienChairman, CEO & President at Bruker00:50:02They also did better last year in getting more platforms out that then over the first year of the deployment that's when the consumables pull through grows as they add more and more assays. Spatial biology and cellular analysis, they both suffered from weak pharma this year and they're both suffering a little bit from weak academic this year. And of course, it gets harder to export things to China when there's 125% increase. So there we're making great progress on taking cost out on efficiency, on putting in a new management process, amazing progress in new competitive products from cellular analysis and spatial biology, but they're both somewhat weaker than what we had expected because of course the U. S. Frank LaukienChairman, CEO & President at Bruker00:50:50ACOGARF this year they both noticed that even as biopharma which was weaker last year is recovering. So that's sort of muted, but I think we're still on track there for looking at a 26 breakeven for these two businesses. Was a quick rundown Tycho. Operator00:51:15The next question comes from Rachel Bedstow of JPMorgan. Go ahead please. Rachel VatnsdalSenior Equity Research Analyst, Healthcare at JPMorgan Chase00:51:22Perfect. Good morning. Thanks so much for taking the questions. So I wanted to follow-up on Mike's earlier question around order book trends. Appreciate all the color you gave us on orders in the quarter and book to bill as well. Rachel VatnsdalSenior Equity Research Analyst, Healthcare at JPMorgan Chase00:51:32But can you talk to us about your expectations for bookings going forward? Do you think we've kind of hit the bottom on orders? Are you expecting it to get worse as we get into the second, third quarter given some of the headlines on NIH budget proposals? And then where are you expecting to exit this year on backlog given you said you still have the seven months of backlog that you're working with? Frank LaukienChairman, CEO & President at Bruker00:51:53I think the academic order weakness I think is just beginning. Q1 or maybe March we saw just a little bit of that. But so U. S. Academic orders and a lot of that headwind this year I think you'll see that in weak U. Frank LaukienChairman, CEO & President at Bruker00:52:09S. Academic government orders in The U. S. In Q2, probably in Q3. And yes, we'll see whether there is some budget flush and grants moving through finally with much delay. Frank LaukienChairman, CEO & President at Bruker00:52:24So but so I think the brunt of that is now coming in Q2 and Q3, hence the revenue headwind that we've taken into account in this new guidance and that we've explained. We have enough other strength in our forecast that we still think will come out at the end of the year with a six point five to seven months backlog. So I know we're all focused on U. S. Aga gov and every day there's a usually not very nice headline. Frank LaukienChairman, CEO & President at Bruker00:52:53But there is other stuff that we do and we are so diversified and so international that we actually still we think our long term normalized backlog should be around 5x now that we have much more consumables and aftermarket that's a little lower than historically when we would have said 5.5x. And I think at this end of this year we'll almost certainly be at 6.5% possibly still at 7%. So that's stubbornly high which is a good thing of course. And you see, I mean, we've outperformed in Q4. We've outperformed in Q1. Frank LaukienChairman, CEO & President at Bruker00:53:25Q2 will be tougher because of some of the transient effects. But I hope that helps your modeling and gives you some additional insights on the timing. Rachel VatnsdalSenior Equity Research Analyst, Healthcare at JPMorgan Chase00:53:35Yes. No, that was great color. Thank you, Frank. And then just my follow-up, I wanted to dig into some of the China stimulus comments. You called out that being a little bit slower in light of the tariff situation and provinces just being slower to release those funds. Rachel VatnsdalSenior Equity Research Analyst, Healthcare at JPMorgan Chase00:53:47So can you unpack that for us a little bit more? How much stimulus revenues did you guys recognize in China in the first quarter? And then are you assuming any China stimulus revenues for the rest of the year? Thanks. Frank LaukienChairman, CEO & President at Bruker00:53:59I know it's more about orders. It was low. It was very little less than $10,000,000 certainly in Q1 as I would think most of the provinces are hanging on to the money if they have it. So it's been deferred while China is trying to figure out what's, you know, what's going on with tariffs and trade war, I assume. So it's it's yeah. Frank LaukienChairman, CEO & President at Bruker00:54:26It's been delayed, essentially. And as I said earlier, we have not baked in by now, you know, now it's May. We have not until that gets even if it got released and then turned into order as well, most of these orders then would might come in in Q3. And by that time, because there that's a lot of high big ticket, cutting edge and leading edge performance things that they order on these stimulus packages, most of that would go into '26 for our revenue. So we don't expect China stimulus to be significant in our P and L in 2025. Rachel VatnsdalSenior Equity Research Analyst, Healthcare at JPMorgan Chase00:55:11Thanks, Frank. Frank LaukienChairman, CEO & President at Bruker00:55:14You're welcome, Rachel. Operator00:55:18The next question comes from Luke Saragotte of Barclays. Go ahead, please. Luke SergottDirector - Healthcare Equity Research at Barclays Capital00:55:24Great. Thanks, guys. I just wanted to dig in a little bit on the 2Q, get some cleanup modeling. Can you just help us with the guide assumptions by the segment for BSI and BEST? What's embedded there for that low single digit constant currency growth, FX, M and A? Luke SergottDirector - Healthcare Equity Research at Barclays Capital00:55:42And then on the operating profit, I understand that the cost outs for that $90,000,000 or the mitigation efforts for that $90,000,000 turned into 45,000,000 Like how much of that 45,000,000 net are you guys looking to hit in that 2Q? Frank LaukienChairman, CEO & President at Bruker00:56:02In Q2? Gerald, that's a Luke SergottDirector - Healthcare Equity Research at Barclays Capital00:56:07long term Frank LaukienChairman, CEO & President at Bruker00:56:08Well, we get the question. Yes. I appreciate it. Probably more of that in Q3 and Q4, right? Gerald HermanExecutive VP & CFO at Bruker00:56:17Yes. Some of the mitigation actions that we've already put in place, around pricing and supply chain items are not going to fall into the second quarter for sure. It's really more about our cost management elements that we're pushing hard on for sure and that will have some modest impact in the second quarter, which is why I think we've triggered a more significant reset on the second quarter expectations. But once those elements kick in, specifically around the third Gerald HermanExecutive VP & CFO at Bruker00:56:52and Gerald HermanExecutive VP & CFO at Bruker00:56:52the fourth quarter, I think there's an expectation that our performance financial performance at the EPS line will improve sharply in the second I mean, sorry, the third and the fourth quarter and the second half of the year. Sort of the big picture. Frank LaukienChairman, CEO & President at Bruker00:57:06So as we've been already slowing hiring and using retirement and attrition and so on, we've been doing that for but some things we can actually implement relatively flexibly. I'll give you an example. In Switzerland and if needed also in Germany, in certain businesses, we can pretty quickly turn down our production capacity by almost about 20% with this short term work mechanisms where basically people end up working 20% less and they're still paid like 95%, ninety eight % because the government kicks in for up to two years. That's a great way of keeping your highly trained workforce and then ramping them back up six months or twelve months later, whatever it will be. We're already doing that. Frank LaukienChairman, CEO & President at Bruker00:57:52So we've announced that in Switzerland, for instance. So it's a very smooth and fast mechanism. And it doesn't require it doesn't cost you as much on the GAAP side in terms of restructuring and cash. And you can also implement it very quickly. But very quickly means still it's mostly going to have a Q3 and Q4 effect and maybe just a tiny bit of an effect. Frank LaukienChairman, CEO & President at Bruker00:58:13It will be effective as of Q2, but it won't move the needle financially yet in Q2. Luke SergottDirector - Healthcare Equity Research at Barclays Capital00:58:20Okay. Thanks. Then I Of Frank LaukienChairman, CEO & President at Bruker00:58:22course, things I'm sorry. There are things like discretionary spending and hiring and we're doing all of these things. Also things that you do on pricing until you put them in the price list and get a new order until you that then works out and pricing also has always a time delay. That's why these things do have effect more into the second half and then much more significant annualized effect next year. Luke SergottDirector - Healthcare Equity Research at Barclays Capital00:58:45Yes. Okay, understood. And then I guess when you talk about the other regions that are doing stimulus like South Korea and Germany and Japan, like I understand that this is more of an out year dynamic and potential tailwind, but with a little context for what those countries have done in the past from a stimulus perspective, have you done any work or have any insight there of what this could look like? Would this look like something like China stimulus in the past where you just get a huge bolus, or is this more infrastructure and more secular? Frank LaukienChairman, CEO & President at Bruker00:59:20Yeah. And I think in Korea, a number is known. And then there was also, I forget, was over three years or something like that, and it was Joe, do you have the number? 46,000,000,000 Of what currency? U. Frank LaukienChairman, CEO & President at Bruker00:59:32S. Dollars? Yes. Okay. So over three years or so, so meaningful. Frank LaukienChairman, CEO & President at Bruker00:59:37Germany is huge, but it will pay for a lot of other stuff. So it's kind of $50,000,000,000 per year over the next ten years. Some of that goes into defense, right? We do have some detection equipment that on the margin goes there. So that's a good trend for us in one of our little niches. Frank LaukienChairman, CEO & President at Bruker00:59:55A lot of it is supposed to go into innovation and technology regaining or expanding where they have a technology leadership. So there's some we're pretty optimistic that a fair that but I can't quantify because it's also as you know the new government was elected yesterday finally. And so they have some really big numbers. Some of that will build bridges. Some of that will build tanks that won't really help us although it may be good for the economy in general. Frank LaukienChairman, CEO & President at Bruker01:00:24But a lot of that probably will also go into innovation including into life science tools. So can't quantify it yet and it will almost certainly be 2026 and beyond. But could be not just the bolus, but a little bit of a longer term trend. Luke SergottDirector - Healthcare Equity Research at Barclays Capital01:00:43Great. Luke SergottDirector - Healthcare Equity Research at Barclays Capital01:00:43Thanks. Frank LaukienChairman, CEO & President at Bruker01:00:43So we'll probably get going for another five minutes or so, going over a little bit. For those who want to stay, we'll try to get to a Frank LaukienChairman, CEO & President at Bruker01:00:49few more a couple more people on questions. Frank LaukienChairman, CEO & President at Bruker01:00:54All right. We move on to the extent they're still on. Operator01:01:00Okay. The next question comes from Subbu Namdi of Guggenheim. Go ahead please. Subbu NambiManaging Director at Guggenheim Securities01:01:08Hey, guys. Good morning. Thank you for taking my question. Agreed BEST is only 10 of the revenue, but do you expect the clinical MRI SUPERCON to eventually improve for Bruker given that it's taking some time for time for AI trends to impact your revenue. One of the things is Bruker's strength is the diversified product portfolio, and therefore, not seeing strength in one of these segment when active government is down always remains a question. Subbu NambiManaging Director at Guggenheim Securities01:01:35Like your the diversified portfolio is supposed to offset all these weaknesses. That's why I'm asking about it. Frank LaukienChairman, CEO & President at Bruker01:01:43So you're talking about the best portfolio. Did I understand that correctly, Google? Subbu NambiManaging Director at Guggenheim Securities01:01:48That's right. Frank LaukienChairman, CEO & President at Bruker01:01:50Yes. Subbu NambiManaging Director at Guggenheim Securities01:01:51Yes. Frank LaukienChairman, CEO & President at Bruker01:01:51I think that's going to be a slower recovery in the MRI market. Obviously, these are other big healthcare companies that you're all familiar with. And the trends there don't fluctuate all that much. So we expect that to be a weak year for BEST. And a reasonably better year for the nearly €100,000,000 RI research instruments component. Frank LaukienChairman, CEO & President at Bruker01:02:22They just had a tough comparison in Q1 year over year. They had an incredible Q1 of last year. So the RI business I think will be not growing fast, but be steady. And the superconducting materials business this year will be weaker probably for the full year, but not as pronounced in a percentage as you would year over year as you've seen in Q1. It will be much more it will stick out less. Frank LaukienChairman, CEO & President at Bruker01:02:55All right. We have one more question for us. Thank you. Thank you, Subbu. One more question, if the next person is on there. Operator01:03:05Okay. Okay. The next question comes from Doug Schenkel of Wolfe Research. Go ahead, please. Doug SchenkelManaging Director at Wolfe Research LLC01:03:13Hey, good morning. Doug SchenkelManaging Director at Wolfe Research LLC01:03:15One question, I guess what I would call portfolio evolution and then just a follow-up on China. So portfolio evolution, some of your bigger acquisitions over the past couple of years ostensibly served to move your revenue mix away from China, and into areas outside of academic research. I'm not saying those were the primary motivations, but, you know, they they're certainly features of a lot of those deals. So China seems like a complete black box right now, and it seems like it plausibly could be structural. Academic government funding, as we've talked about extensively, is at risk globally. Doug SchenkelManaging Director at Wolfe Research LLC01:03:51So I guess what I'm wondering is when would you expect the deals you did in '23 and '24 to grow year over year on a same store sales basis? Is is is that gonna happen in '25 and '26? Are we kind of in the background starting to see the benefits of portfolio evolution? So that's that's Oh, absolutely. Frank LaukienChairman, CEO & President at Bruker01:04:10Yeah. Frank LaukienChairman, CEO & President at Bruker01:04:12Why don't why don't I And yeah. Go ahead, Zach. Doug SchenkelManaging Director at Wolfe Research LLC01:04:17Why don't we answer that and we'll come back to China in a second. Frank LaukienChairman, CEO & President at Bruker01:04:21Okay. And then we'll wrap it up. Frank LaukienChairman, CEO & President at Bruker01:04:23So yes, absolutely. The portfolio evolution is already visible. I mean, is steady and as can be. And when other things are weaker, steady high single digit growth in diagnostics, molecular microbiology is awesome. Of course, a lot of consumables, so that works. Frank LaukienChairman, CEO & President at Bruker01:04:43The automation and multiple smaller software, scientific software acquisitions, I kind of take them a little bit together because they feed each other towards the digitized lab, more automated lab. That's all working really nicely. And even as people are a little people biopharma and other industries, clean tech and fine chemicals, love to invest in that because can't either can't find the staffing or they're prepared to do it with more productivity and less hands on time. So those are all good trends. The investments of the old Berkeley Lights, which is cellular analysis, the beacon platform, as many of you know it, and about that third of spatial biology that does go into biopharma. Frank LaukienChairman, CEO & President at Bruker01:05:34Yes, they're helping us in the biopharma recovery. So that a lot of these things are already active and are offsetting some of the AGAW weakness. Without the portfolio evolution, including the pretty rapid evolution with our acquisitions in the last five, six quarters or so, this would be a tougher call and maybe we wouldn't maybe we'd go down organically this year. We think we'll still grow a little bit despite all of the headwinds. Thank you for China is hard to read. Frank LaukienChairman, CEO & President at Bruker01:06:10I agree. Doug SchenkelManaging Director at Wolfe Research LLC01:06:11Yes. My question there was just going to be and I know I'll keep it tight. If we think about even what you guys were saying a month, month and a half ago about orders related to China stimulus. You know, it it obviously sounds different today, and a lot has changed in that period. My my question is really, you know, do you think, in general, your visibility on what's going on in China and what's going to happen in China is just a lot lower than it has been for the last decade? Doug SchenkelManaging Director at Wolfe Research LLC01:06:48And do you think you have that adequately captured in guidance at this point? Frank LaukienChairman, CEO & President at Bruker01:06:54It is lower. And I hope we've got it captured because we're not built. There is stimulus plans. It's amazing when some of our executives are over there. The projects that are ready approved by the university, maybe even approved locally, just no funding yet, would be quite favorable for us in NMR, mass spec and other fields. Frank LaukienChairman, CEO & President at Bruker01:07:18But the funding doesn't get released. And I don't know whether it gets released ever or in Q2 or Q3 or Q4. And I don't think they know. However, unlike past China stimulus programs, which were sort of one or two quarter wonders, this one seems to be much more sustained. And so some of the professors or PIs of large consortia for academic medical research, they say, yeah, yeah, this will get funded. Frank LaukienChairman, CEO & President at Bruker01:07:47We just don't know whether this year or next year, and worst case in three years. But this will get funded. This is a priority. So it's more that but the timing is really there is no visibility into timing, and they don't have it either. It could be next quarter. Frank LaukienChairman, CEO & President at Bruker01:08:06It could be next year. They're all pretty confident they'll they'll get it. That's the answer. Wish I knew the timing. But that's how it works right now. Frank LaukienChairman, CEO & President at Bruker01:08:18Yeah. All right. Nine forty. So we have ten minutes over. Yeah. Operator01:08:24Okay. This concludes our question and answer session. I would like to turn the conference back over to Joe Kostka for any closing remarks. Joe KostkaDirector, Head of Investor Relations at Bruker01:08:35Thank you for joining us today. Bruker's leadership team looks forward to meeting with you at an event or speaking with you directly during the second quarter. Feel free to reach out to me to arrange any follow ups, and have a good day. Thank you. Operator01:08:51The conference has now concluded. Thank you for attending today's presentation. You may now disconnect.Read moreParticipantsExecutivesJoe KostkaDirector, Head of Investor RelationsFrank LaukienChairman, CEO & PresidentGerald HermanExecutive VP & CFOAnalystsPuneet SoudaSenior MD at Leerink PartnersMichael RyskinManaging Director at Bank of America Merrill LynchPatrick DonnellyManaging Director at CitiTycho PetersonManaging Director, Global Equities at Jefferies Financial GroupRachel VatnsdalSenior Equity Research Analyst, Healthcare at JPMorgan ChaseLuke SergottDirector - Healthcare Equity Research at Barclays CapitalSubbu NambiManaging Director at Guggenheim SecuritiesDoug SchenkelManaging Director at Wolfe Research LLCPowered by