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Amicus Therapeutics Q4 2025 Earnings Results & Report

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Amicus Therapeutics missed analyst earnings expectations but beat on revenue in its Q4 2025 results, released February 20, 2026. The company reported EPS of $0.10 versus the $0.13 consensus estimate, while revenue of $185.21 million topped the $185.00 million estimate by $0.21 million. Revenue increased 23.7% year over year.

Earnings Announcement Details

Quarter
Q4 2025
Time
Before Market Opens
Conference Call
4:00 PM ET

Amicus Therapeutics EPS Results

Actual EPS
$0.10
Consensus EPS
$0.13
Beat/Miss
Missed by -$0.03
One Year Ago EPS
$0.09
EPS Beat Rate
3 of last 8 quarters

Amicus Therapeutics Revenue Results

Actual Revenue
$185.21 million
Expected Revenue
$185.00 million
Beat/Miss
Beat by +$212.00 thousand
YoY Revenue Growth
+23.70%

Amicus Therapeutics Q4 2025 Earnings FAQ

Amicus Therapeutics (NASDAQ:FOLD) reported earnings of $0.10 per share for Q4 2025, missing the consensus estimate of $0.13. The report was announced on Friday, February 20, 2026.

Amicus Therapeutics reported revenue of $185.21 million for Q4 2025, against a consensus estimate of $185.00 million.

Amicus Therapeutics Earnings Headlines

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About Amicus Therapeutics

Amicus Therapeutics (NASDAQ:FOLD) (NASDAQ:FOLD) is a biopharmaceutical company focused on the discovery, development and commercialization of treatments for rare and orphan diseases. The company specializes in pharmacological chaperones and gene therapy approaches designed to address the underlying causes of lysosomal storage disorders. Its proprietary technology platform integrates structure‐based drug design with precision medicine to identify small molecules that stabilize misfolded proteins and restore cellular function.

The company’s lead marketed product, Galafold (migalastat), is an oral pharmacological chaperone approved in the United States, European Union and other territories for the treatment of Fabry disease in patients with amenable genetic variants. Beyond Fabry disease, Amicus is advancing a pipeline of investigational gene therapies and combination therapies, including programs targeting Pompe disease and Batten disease, with several candidates in late‐stage and mid‐stage clinical development.

Founded in 2005 and headquartered in Cranbury, New Jersey, Amicus Therapeutics completed its initial public offering on the NASDAQ in 2015. The company maintains research and development operations in multiple locations across the United States and Europe, leveraging global manufacturing and regulatory expertise to support its clinical trials and commercial supply chain.

Leadership at Amicus includes Chief Executive Officer Chirfi Guindo, who brings extensive experience in rare disease drug development, and John Crowley, co‐founder and Chairman of the Board. The company collaborates with leading pharmaceutical and academic partners to expand its platform and accelerate the development of novel therapies for underserved patient communities.

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