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NASDAQ:DNLI

Denali Therapeutics Q4 2025 Earnings Results & Report

Denali Therapeutics logo
$17.61 -0.73 (-3.98%)
Closing price 10/16/2026 04:00 PM Eastern
Extended Trading
$17.92 +0.32 (+1.79%)
As of 10/16/2026 07:30 PM Eastern
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Denali Therapeutics beat analyst earnings expectations in its Q4 2025 results, released February 26, 2026. The company reported EPS of -$0.73 versus the -$0.75 consensus estimate.

Earnings Announcement Details

Quarter
Q4 2025
Time
Before Market Opens
Conference Call
7:00 AM ET

Denali Therapeutics EPS Results

Actual EPS
-$0.73
Consensus EPS
-$0.75
Beat/Miss
Beat by +$0.02
One Year Ago EPS
-$0.67
EPS Beat Rate
5 of last 8 quarters

Denali Therapeutics Revenue Results

Actual Revenue
N/A
Expected Revenue
$2.86 million
Beat/Miss
N/A
YoY Revenue Growth
N/A

Upcoming Earnings

Denali Therapeutics' Q3 2026 earnings is estimated for Thursday, November 5, 2026, based on past reporting schedules, with a conference call scheduled at 4:00 PM ET. Check back for transcripts, audio, and key financial metrics as they become available.

Denali Therapeutics Q4 2025 Earnings FAQ

Denali Therapeutics (NASDAQ:DNLI) reported earnings of -$0.73 per share for Q4 2025, beating the consensus estimate of -$0.75. The report was announced on Thursday, February 26, 2026.

Denali Therapeutics' next earnings date is estimated for Thursday, November 5, 2026. MarketBeat tracks confirmed and estimated earnings dates for Denali Therapeutics on the company's earnings history page.

Denali Therapeutics Earnings Headlines

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About Denali Therapeutics

Denali Therapeutics (NASDAQ:DNLI) is a biopharmaceutical company focused on discovering and developing medicines for patients with neurodegenerative diseases. The company’s research programs address conditions involving the central nervous system, including Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis and lysosomal storage disorders.

Denali’s drug-discovery approach is built around its Transport Vehicle platform, which is designed to help therapeutic molecules cross the blood-brain barrier and reach the brain. Its pipeline has included small-molecule therapies, biologic medicines and enzyme-replacement treatments targeting disease pathways such as LRRK2, TREM2 and lysosomal dysfunction. The company advances candidates through research and clinical development and has entered into collaborations with larger pharmaceutical companies, including Biogen and Takeda.

Founded in 2013, Denali is headquartered in South San Francisco, California. The company was co-founded by Ryan Watts, Ph.D., who serves as chief executive officer. Its programs are developed for potential use in global markets, with clinical research and collaborations supporting the development of treatments for patients with serious neurological and neurodegenerative conditions.

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