NASDAQ:XLO Xilio Therapeutics Q4 2025 Earnings Results & Report $7.80 -0.44 (-5.28%) As of 12:34 PM Eastern This is a fair market value price provided by Massive. Learn more. Xilio Therapeutics beat analyst expectations on both earnings and revenue in its Q4 2025 results, released March 23, 2026. The company reported EPS of -$0.85 versus the -$1.68 consensus estimate, while revenue of $13.69 million topped the $10.90 million estimate by $2.79 million. Research:ProfileEarnings HistoryForecast Earnings Announcement Details QuarterQ4 2025Report DateMarch 23, 2026TimeBefore Market Opens Xilio Therapeutics EPS ResultsActual EPS-$0.85Consensus EPS -$1.68Beat/MissBeat by +$0.83One Year Ago EPSN/AEPS Beat Rate5 of last 8 quartersXilio Therapeutics Revenue ResultsActual Revenue$13.69 millionExpected Revenue$10.90 millionBeat/MissBeat by +$2.79 millionYoY Revenue GrowthN/AConference Call ResourcesPress Release (8-K)Annual Report (10-K)Annual ReportEarnings HistoryCompany ProfilePowered by Earnings DocumentsPress Release(8-K)Annual report(10-K)Annual report Xilio Therapeutics Q4 2025 Earnings FAQ Did Xilio Therapeutics beat earnings estimates for Q4 2025? Xilio Therapeutics (NASDAQ:XLO) reported earnings of -$0.85 per share for Q4 2025, beating the consensus estimate of -$1.68. The report was announced on Monday, March 23, 2026. What was Xilio Therapeutics' revenue for Q4 2025? Xilio Therapeutics reported revenue of $13.69 million for Q4 2025, against a consensus estimate of $10.90 million. Xilio Therapeutics Earnings HeadlinesXilio Therapeutics, Inc. Reports Earnings Results for the Third Quarter and Nine Months Ended September 30, 2026November 11 at 9:56 AM | marketscreener.comMXilio Doses First Patient In XTX501 Cancer Trial; Plans 2027 Data ReadoutNovember 10 at 2:46 PM | rttnews.comYour free book is about to disappearBill Poulos is giving away his 'Safe Trade Options Formula' book for free - but only for a limited time through a temporary download link. He plans to charge for it soon. Download your copy now and lock it in at no cost, regardless of future pricing.November 13 at 1:00 AM | Profits Run (Ad)Xilio Therapeutics Reports Third Quarter 2026 Financial Results and Provides Pipeline and Business UpdatesNovember 10 at 7:30 AM | globenewswire.comXilio Therapeutics (XLO) Projected to Announce Quarterly Earnings on ThursdayNovember 5, 2026 | americanbankingnews.comXilio Therapeutics (NASDAQ:XLO) Stock Price Breaks Above Two Hundred Day Moving Average - Here's WhyNovember 4, 2026 | americanbankingnews.comSee More Xilio Therapeutics Headlines Get Earnings Announcements in your inboxWant to stay updated on the latest earnings announcements and upcoming reports for companies like Xilio Therapeutics? Sign up for Earnings360's daily newsletter to receive timely earnings updates on Xilio Therapeutics and other key companies, straight to your email. Email Address About Xilio TherapeuticsXilio Therapeutics (NASDAQ:XLO) is a clinical-stage biotechnology company focused on developing tumor-activated immunotherapies for cancer. The company’s technology is designed to keep powerful immune-modulating medicines inactive in healthy tissue and activate them preferentially within the tumor microenvironment, with the goal of improving antitumor activity while reducing systemic side effects. Xilio’s research and development programs have included engineered cytokines and immune checkpoint therapies, including tumor-activated versions of interleukin-2, interleukin-12 and CTLA-4-directed treatments. Its pipeline is intended to stimulate immune responses within solid tumors and potentially address cancers that have limited responses to existing immunotherapies. The company’s programs remain in clinical development and are subject to the risks and uncertainties associated with biotechnology research. Founded in 2020 and headquartered in Waltham, Massachusetts, Xilio Therapeutics serves the global oncology market through its drug-discovery and clinical-development activities. The company became publicly traded on the Nasdaq under the symbol XLO in 2021. Xilio is led by René Russo, who serves as president and chief executive officer.View Xilio Therapeutics ProfileRead more More Earnings Resources from MarketBeat Earnings Tools Today's Earnings Tomorrow's Earnings Next Week's Earnings Upcoming Earnings Calls Earnings Newsletter Earnings Call Transcripts Earnings Beats & Misses Corporate Guidance Earnings Screener Latest Articles Costco's Record $30 Dividend Shows Just How Strong Its Cash Machine IsThese 3 Stocks Have Bought Back Billions, But Which Offers the Best Value?Hims & Hers Bounced Back 9%, But Its Earnings Reveal a Costly Trade-OffSix Flags Lost $366 Million in Q3—Its Insiders Just Went ShoppingGolden Dome’s $185 Billion Question: Who Actually Gets Paid?3 Pharmaceutical Stocks That Offer Safety and GrowthFirefly Aerospace Lights Up a High-Risk Space Opportunity Upcoming Earnings Home Depot (11/17/2026)Walt Disney (11/17/2026)NVIDIA (11/17/2026)Lowe's Companies (11/18/2026)PDD (11/18/2026)TJX Companies (11/18/2026)Target (11/18/2026)Palo Alto Networks (11/18/2026)NetEase (11/19/2026)Alibaba Group (11/19/2026) Unlock superior investment research and tools. 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