Seres Therapeutics (MCRB) Stock Price, News & Analysis

Company Overview

Seres Therapeutics, Inc., a microbiome therapeutics company, develop microbiome therapeutics to treat the modulation of the colonic microbiome. It develops a novel class of biological drugs that are designed to treat by modulating the microbiome to restore health by repairing the function of a disrupted microbiome to a non-disease state. The company's lead product candidate is VOWST, an oral microbiome therapeutic that has completed Phase III clinical trial for the treatment of recurrent Clostridioides difficile infection. Its product pipeline also includes SER-155, an investigational oral fermented microbiome therapeutic which is in Phase 1b clinical trials for the treatment of gastrointestinal infections, bacteremia, and graft versus host disease in immunocompromised patients including patients receiving allogeneic hematopoietic stem cell transplantation. In addition, the company engages in the development of SER-287 which is in Phase 2b and SER-301 that is in Phase 1b to treat ulcerative colitis. Further, it has license Agreement with NHSc Rx License GmbH for the therapeutic products based on the microbiome technology, which includes VOWST product candidate, which is developed for the treatment of CDI and recurrent CDI; and collaboration license agreement with Société des Produits Nestlé S.A. (Nestlé) for the development and commercialization of certain product candidates for the treatment and management of CDI and inflammatory bowel disease including UC and Crohn's disease. The company was formerly known as Seres Health, Inc. and changed its name to Seres Therapeutics, Inc. in May 2015. Seres Therapeutics, Inc. was incorporated in 2010 and is headquartered in Cambridge, Massachusetts.

Key Stats

• Today's Range: $16.49 to $17.17
• 50-Day Range: $7.32 to $16.86
• 52-Week Range: $6.53 to $26.40
• Volume: 55,391 shs
• Average Volume: 132,996 shs
• Market Capitalization: $146.04 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $73.67
• Consensus Rating: Reduce

Seres Therapeutics Stock Analysis - MarketRank™

Seres Therapeutics scored higher than 66% of companies evaluated by MarketBeat, and ranked 725th out of 1,876 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 2.9 / 5
• Analyst Rating: Reduce

Consensus Rating

Seres Therapeutics has received a consensus rating of Reduce. The company's average rating score is 1.75, and is based on 1 buy rating, 1 hold rating, and 2 sell ratings.

Amount of Analyst Coverage

Seres Therapeutics has received no research coverage in the past 90 days.

Earnings and Valuation

• Score: 0.0 / 5
• Proj. Earnings Growth: Decreasing

Earnings Growth

Earnings for Seres Therapeutics are expected to decrease in the coming year, from ($0.38) to ($0.56) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Seres Therapeutics is -3.63, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Seres Therapeutics is -3.63, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Seres Therapeutics has a P/B Ratio of 10.37. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.

Short Interest

• Score: 1.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

15.50% of the float of Seres Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Seres Therapeutics has a short interest ratio ("days to cover") of 8.3.

Change versus previous month

Short interest in Seres Therapeutics has recently increased by 16.13%, indicating that investor sentiment is decreasing significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Seres Therapeutics does not currently pay a dividend.

Dividend Growth

Seres Therapeutics does not have a long track record of dividend growth.

Sustainability and ESG

• Score: 4.6 / 5
• Environmental Score: -1.14

Percentage of Shares Shorted

15.50% of the float of Seres Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Seres Therapeutics has a short interest ratio ("days to cover") of 8.3.

Change versus previous month

Short interest in Seres Therapeutics has recently increased by 16.13%, indicating that investor sentiment is decreasing significantly.

News and Social Media

• Score: 3.0 / 5
• News Sentiment: 1.36

News Sentiment

Seres Therapeutics has a news sentiment score of 1.36. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.65 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 2 news articles for Seres Therapeutics this week, compared to 2 articles on an average week.

Search Interest

8 people have searched for MCRB on MarketBeat in the last 30 days. This is an increase of 33% compared to the previous 30 days.

Company Ownership

• Score: 0.8 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, Seres Therapeutics insiders have not sold or bought any company stock.

Percentage Held by Insiders

Only 4.70% of the stock of Seres Therapeutics is held by insiders.

Percentage Held by Institutions

59.34% of the stock of Seres Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

MCRB Stock Analysis - Frequently Asked Questions

How have MCRB shares performed this year?

Seres Therapeutics' stock was trading at $16.62 at the start of the year. Since then, MCRB stock has increased by 0.4% and is now trading at $16.69.

How were Seres Therapeutics' earnings last quarter?

Seres Therapeutics, Inc. (NASDAQ:MCRB) released its quarterly earnings data on Wednesday, August, 6th. The biotechnology company reported ($2.27) earnings per share for the quarter, topping analysts' consensus estimates of ($2.72) by $0.45.
Read the conference call transcript.

When did Seres Therapeutics' stock split?

Seres Therapeutics's stock reverse split on the morning of Tuesday, April 22nd 2025.The 1-20 reverse split was announced on Thursday, April 10th 2025. The number of shares owned by shareholders was adjusted after the market closes on Monday, April 21st 2025. An investor that had 100 shares of stock prior to the reverse split would have 5 shares after the split.

When did Seres Therapeutics IPO?

Seres Therapeutics (MCRB) raised $101 million in an IPO on Friday, June 26th 2015. The company issued 6,300,000 shares at a price of $15.00-$17.00 per share. Goldman Sachs and BofA Merrill Lynch acted as the underwriters for the IPO and Leerink Partners and Canaccord Genuity were co-managers.

Who are Seres Therapeutics' major shareholders?

Top institutional shareholders of Seres Therapeutics include Geode Capital Management LLC (1.05%), Marshall Wace LLP (1.04%), Vontobel Holding Ltd. (0.92%) and XTX Topco Ltd (0.26%). Insiders that own company stock include Eric D Shaff, Thomas Desrosier, Matthew R Henn, Teresa L Young, David S Ege, Paula Cloghessy and Moltke Lisa Von.
View institutional ownership trends.

How do I buy shares of Seres Therapeutics?

Shares of MCRB stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Seres Therapeutics own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Seres Therapeutics investors own include PayPal (PYPL), NVIDIA (NVDA), Meta Platforms (META), Tesla (TSLA), Micron Technology (MU), QUALCOMM (QCOM) and NIO (NIO).

Company Calendar

• Last Earnings: 8/06/2025
• Today: 8/18/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:MCRB
• CIK: 1609809
• Web: www.serestherapeutics.com
• Phone: (617) 945-9626
• Fax: N/A
• Employees: 330
• Year Founded: 2010

Price Target and Rating

• Average Price Target for Seres Therapeutics: $73.67
• High Price Target: $200.00
• Low Price Target: $6.00
• Potential Upside/Downside: +341.4%
• Consensus Rating: Reduce
• Rating Score (0-4): 1.75
• Research Coverage: 4 Analysts

Profitability

• EPS (Trailing Twelve Months): ($4.60)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: $140 thousand
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: -350.16%
• Return on Assets: -67.69%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 1.57
• Quick Ratio: 1.57

Sales & Book Value

• Annual Sales: $126.32 million
• Price / Sales: 1.16
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $1.61 per share
• Price / Book: 10.37

Miscellaneous

• Outstanding Shares: 8,750,000
• Free Float: 8,344,000
• Market Cap: $146.04 million
• Optionable: Optionable
• Beta: 2.90