Seres Therapeutics (MCRB) Stock Price, News & Analysis

Company Overview

Seres Therapeutics is a clinical‐stage microbiome therapeutics company focused on harnessing the power of the human microbiome to treat serious diseases. Headquartered in Cambridge, Massachusetts, Seres applies proprietary microbiome science and manufacturing capabilities to develop a pipeline of living microbial therapies designed to restore healthy gut function. The company’s approach leverages understanding of microbial ecology and human biology to address conditions where the native microbiome is disrupted.

Among its lead candidates is SER-109, an investigational oral microbiome therapeutic for reducing recurrence of Clostridioides difficile infection. Seres is also advancing SER-287 in ulcerative colitis, SER-401 in combination with immunotherapy for certain cancers, and other preclinical programs targeting metabolic and inflammatory diseases. The company collaborates with strategic partners, including Nestlé Health Science, to support development, manufacturing scale-up and global research efforts.

Founded in 2010, Seres went public in 2015 to further accelerate its clinical pipeline. The management team comprises experienced biotech executives, clinicians and scientists with expertise in microbiome research and product development. Seres continues to conduct multi‐center clinical trials across North America and Europe, seeking to bring first‐in‐class microbiome therapies to patients with limited treatment options.

Key Stats

• Today's Range: $4.65 to $4.99
• 50-Day Range: $4.65 to $8.14
• 52-Week Range: $4.59 to $29.98
• Volume: 51,175 shs
• Average Volume: 92,339 shs
• Market Capitalization: $46.77 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $17.00
• Consensus Rating: Hold

Seres Therapeutics Stock Analysis - MarketRank™

Seres Therapeutics scored higher than 51% of companies evaluated by MarketBeat, and ranked 484th out of 894 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.7 / 5
• Analyst Rating: Hold

Consensus Rating

Seres Therapeutics has received a consensus rating of Hold. The company's average rating score is 2.25, and is based on no strong buy ratings, 2 buy ratings, 1 hold rating, and 1 sell rating.

Upside Potential

Seres Therapeutics has a consensus price target of $17.00, representing about 252.0% upside from its current price of $4.83.

Amount of Analyst Coverage

Seres Therapeutics has only been the subject of 3 research reports in the past 90 days.

Earnings and Valuation

• Score: 1.3 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for Seres Therapeutics are expected to grow in the coming year, from ($5.84) to ($2.87) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Seres Therapeutics is -0.93, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Seres Therapeutics is -0.93, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Seres Therapeutics has a P/B Ratio of 0.99. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.

Short Interest

• Score: 3.0 / 5
• Short Interest Level: Healthy

Percentage of Shares Shorted

3.31% of the float of Seres Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Seres Therapeutics has a short interest ratio ("days to cover") of 2, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Seres Therapeutics has recently increased by 92.86%, indicating that investor sentiment is decreasing significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Seres Therapeutics does not currently pay a dividend.

Dividend Growth

Seres Therapeutics does not have a long track record of dividend growth.

News and Social Media

• Score: 0.6 / 5
• News Sentiment: N/A

Search Interest

1 people have searched for MCRB on MarketBeat in the last 30 days.

Company Ownership

• Score: 0.9 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, Seres Therapeutics insiders have not sold or bought any company stock.

Percentage Held by Insiders

5.20% of the stock of Seres Therapeutics is held by insiders.

Percentage Held by Institutions

59.34% of the stock of Seres Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

Company Calendar

• Last Earnings: 5/05/2026
• Today: 8/02/2026
• Next Earnings (Estimated): 8/05/2026
• Fiscal Year End: 12/31/2026

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Healthcare
• Industry: Biotechnology
• Sub-Industry: Biotechnology
• Current Symbol: NASDAQ:MCRB
• CIK: 1609809
• Web: www.serestherapeutics.com
• Phone: (617) 945-9626
• Fax: N/A
• Employees: 330
• Year Founded: 2010

Price Target and Rating

• Average Price Target for Seres Therapeutics: $17.00
• High Price Target: $22.00
• Low Price Target: $12.00
• Potential Upside/Downside: +252.0%
• Consensus Rating: Hold
• Rating Score (0-4): 2.25
• Research Coverage: 4 Analysts

Profitability

• EPS (Trailing Twelve Months): ($5.17)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: $5.70 million
• Net Margins: N/A
• Pretax Margin: -4,088.84%
• Return on Equity: -130.29%
• Return on Assets: -35.35%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 1.65
• Quick Ratio: 1.65

Sales & Book Value

• Annual Sales: $1.15 million
• Price / Sales: 40.78
• Cash Flow: $1.09 per share
• Price / Cash Flow: 4.45
• Book Value: $4.89 per share
• Price / Book: 0.99

Miscellaneous

• Outstanding Shares: 9,684,000
• Free Float: 9,180,000
• Market Cap: $46.77 million
• Optionable: Optionable
• Beta: 0.09