NASDAQ:CRNX Crinetics Pharmaceuticals (CRNX) Stock Price, News & Analysis $34.70 -2.07 (-5.63%) Closing price 05/18/2026 04:00 PM EasternExtended Trading$35.33 +0.63 (+1.80%) As of 07:01 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Crinetics Pharmaceuticals Stock (NASDAQ:CRNX) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get CRNX alerts:Sign Up Key Stats Today's Range$34.63▼$37.4650-Day Range$33.67▼$43.5852-Week Range$25.83▼$57.99Volume822,686 shsAverage Volume1.43 million shsMarket Capitalization$3.66 billionP/E RatioN/ADividend YieldN/APrice Target$76.13Consensus RatingModerate Buy Company Overview Crinetics Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of novel therapeutics for rare endocrine diseases. The company’s proprietary platform leverages insights into hormone receptor signaling to design small-molecule candidates that address conditions driven by dysregulated hormone activity. Crinetics’ research efforts center on targeting somatostatin, vasopressin and other GPCR-mediated pathways with orally bioavailable molecules intended to improve patient convenience and adherence. The company’s lead product candidate, paltusotine (formerly CRN04777), is a selective, non-peptide somatostatin receptor type 2 agonist being evaluated for the treatment of acromegaly and carcinoid syndrome diarrhea. In parallel, Crinetics is advancing CRN04894, a vasopressin V2 receptor antagonist for the management of hyponatremia, and CRN04912, an oral ghrelin receptor inverse agonist being developed for congenital hyperinsulinism. These programs reflect Crinetics’ strategy to build a focused pipeline addressing multiple rare endocrine disorders with high unmet medical need. Founded in 2013 and headquartered in San Diego, California, Crinetics Pharmaceuticals operates with an organizational structure designed to support both in-house discovery and external collaborations. The company engages with academic research centers and clinical investigators across North America and Europe to advance its clinical studies and to explore additional indications for its pipeline candidates. Crinetics’ integrated approach combines medicinal chemistry, translational biology and clinical development expertise under one roof, with the goal of accelerating the path from laboratory to patient care. As a publicly traded company on the NASDAQ under the ticker CRNX, Crinetics maintains a governance framework led by a board of directors and an executive leadership team with deep experience in endocrinology, drug development and regulatory affairs. The company continues to invest in expanding its pipeline and strengthening its scientific capabilities to bring new treatment options to patients with rare hormonal disorders.AI Generated. May Contain Errors. Read More Crinetics Pharmaceuticals Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks45th Percentile Overall ScoreCRNX MarketRank™: Crinetics Pharmaceuticals scored higher than 45% of companies evaluated by MarketBeat, and ranked 647th out of 859 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.1 / 5Analyst RatingModerate Buy Consensus RatingCrinetics Pharmaceuticals has received a consensus rating of Moderate Buy. The company's average rating score is 2.90, and is based on 1 strong buy rating, 8 buy ratings, no hold ratings, and 1 sell rating.Upside PotentialCrinetics Pharmaceuticals has a consensus price target of $76.13, representing about 119.4% upside from its current price of $34.70.Amount of Analyst CoverageCrinetics Pharmaceuticals has only been the subject of 3 research reports in the past 90 days.Read more about Crinetics Pharmaceuticals' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Crinetics Pharmaceuticals are expected to grow in the coming year, from ($4.82) to ($4.24) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Crinetics Pharmaceuticals is -6.76, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Crinetics Pharmaceuticals is -6.76, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioCrinetics Pharmaceuticals has a P/B Ratio of 3.57. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Crinetics Pharmaceuticals' valuation and earnings. Short Interest0.0 / 5Short Interest LevelBearish Percentage of Shares Shorted13.97% of the float of Crinetics Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverCrinetics Pharmaceuticals has a short interest ratio ("days to cover") of 12.7, which indicates bearish sentiment.Change versus previous monthShort interest in Crinetics Pharmaceuticals has recently increased by 10.74%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldCrinetics Pharmaceuticals does not currently pay a dividend.Dividend GrowthCrinetics Pharmaceuticals does not have a long track record of dividend growth. News and Social Media1.9 / 5News Sentiment0.09 News SentimentCrinetics Pharmaceuticals has a news sentiment score of 0.09. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.59 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 19 news articles for Crinetics Pharmaceuticals this week, compared to 5 articles on an average week.Search InterestOnly 4 people have searched for CRNX on MarketBeat in the last 30 days. This is a decrease of -43% compared to the previous 30 days.MarketBeat FollowsOnly 1 people have added Crinetics Pharmaceuticals to their MarketBeat watchlist in the last 30 days. This is a decrease of 0% compared to the previous 30 days. Company Ownership1.6 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Crinetics Pharmaceuticals insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $5,569,475.00 in company stock.Percentage Held by Insiders3.80% of the stock of Crinetics Pharmaceuticals is held by insiders.Percentage Held by Institutions98.51% of the stock of Crinetics Pharmaceuticals is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Crinetics Pharmaceuticals' insider trading history. Receive CRNX Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Crinetics Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. 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CRNX Stock News HeadlinesCrinetics Pharmaceuticals (NASDAQ:CRNX) Raised to Sell at Wall Street ZenMay 17 at 1:07 AM | americanbankingnews.comCrinetics Pharmaceuticals Inc CRNXMay 15, 2026 | morningstar.comMElon Musk’s $1 Quadrillion AI IPO$1 quadrillion would be enough to send a $2.8 million check to every man, woman, and child in America. That is the scale of what analysts are calling the biggest AI IPO in history.And right now, you can claim a stake before the company goes public, starting with just $500.Elon Musk is predicting this investment could climb 1,000x from here. Early access is available today.May 19 at 1:00 AM | Brownstone Research (Ad)Financial Analysis: Cronos Group (NASDAQ:CRON) vs. Crinetics Pharmaceuticals (NASDAQ:CRNX)May 15, 2026 | americanbankingnews.comIndustry Analysts Just Upgraded Their Crinetics Pharmaceuticals, Inc. (NASDAQ:CRNX) Revenue Forecasts By 11%May 14, 2026 | finance.yahoo.comCrinetics Pharmaceuticals, Inc. 2026 Q1 - Results - Earnings Call PresentationMay 12, 2026 | seekingalpha.comCrinetics Pharmaceuticals (NASDAQ:CRNX) Price Target Cut to $84.00 by Analysts at OppenheimerMay 12, 2026 | americanbankingnews.comCrinetics Pharmaceuticals, Inc. (NASDAQ:CRNX) Just Reported First-Quarter Earnings And Analysts Are Lifting Their EstimatesMay 11, 2026 | finance.yahoo.comSee More Headlines CRNX Stock Analysis - Frequently Asked Questions How have CRNX shares performed this year? Crinetics Pharmaceuticals' stock was trading at $46.55 at the start of the year. Since then, CRNX shares have decreased by 25.5% and is now trading at $34.70. How were Crinetics Pharmaceuticals' earnings last quarter? Crinetics Pharmaceuticals, Inc. (NASDAQ:CRNX) announced its quarterly earnings results on Thursday, May, 7th. The company reported ($1.23) EPS for the quarter, missing the consensus estimate of ($1.22) by $0.01. Crinetics Pharmaceuticals's quarterly revenue was up 2873.4% on a year-over-year basis. Read the conference call transcript. When did Crinetics Pharmaceuticals IPO? Crinetics Pharmaceuticals (CRNX) raised $96 million in an initial public offering on Wednesday, July 18th 2018. The company issued 6,000,000 shares at a price of $15.00-$17.00 per share. J.P. Morgan, Leerink Partners and Piper Jaffray acted as the underwriters for the IPO. Who are Crinetics Pharmaceuticals' major shareholders? Crinetics Pharmaceuticals' top institutional shareholders include Janus Henderson Group PLC (4.29%), Siren L.L.C. (1.81%), Pictet Asset Management Holding SA (1.80%) and ADAR1 Capital Management LLC (1.08%). Insiders that own company stock include Richard Scott Struthers, Stephen F Betz, Marc Wilson, Jeff E Knight, Tobin Schilke, Dana Pizzuti, Alan Seth Krasner, James Hassard, Matthew K Fust, Coelho Rogerio Vivaldi, Stephanie Okey and Isabel Kalofonos. View institutional ownership trends. How do I buy shares of Crinetics Pharmaceuticals? Shares of CRNX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Crinetics Pharmaceuticals own? Based on aggregate information from My MarketBeat watchlists, some other companies that Crinetics Pharmaceuticals investors own include NVIDIA (NVDA), Broadcom (AVGO), Meta Platforms (META), Arista Networks (ANET), Adobe (ADBE), ServiceNow (NOW) and Advanced Micro Devices (AMD). Company Calendar Last Earnings5/07/2026Today5/19/2026Next Earnings (Estimated)8/06/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Yellow Zone (1w+) 1-Year History May 25 Aug 25 Nov 25 Feb 26 May 26 For the last 11 days, CRNX's financial health has been in the Yellow zone, according to TradeSmith. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - DRUGS Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:CRNX CIK1658247 Webwww.crinetics.com Phone(858) 450-6464FaxN/AEmployees210Year Founded2008Price Target and Rating Average Price Target for Crinetics Pharmaceuticals$76.13 High Price Target$95.00 Low Price Target$52.00 Potential Upside/Downside+119.4%Consensus RatingModerate Buy Rating Score (0-4)2.90 Research Coverage10 Analysts Profitability EPS (Trailing Twelve Months)($5.13) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$465.32 million Net Margins-2,747.18% Pretax Margin-2,746.18% Return on Equity-43.96% Return on Assets-39.61% Debt Debt-to-Equity RatioN/A Current Ratio18.60 Quick Ratio18.56 Sales & Book Value Annual Sales$7.70 million Price / Sales475.16 Cash FlowN/A Price / Cash FlowN/A Book Value$9.71 per share Price / Book3.57Miscellaneous Outstanding Shares105,440,000Free Float101,433,000Market Cap$3.66 billion OptionableOptionable Beta0.28 Social Links Don't wait for the SpaceX IPOThe space race is growing fast, and you don’t have to wait for SpaceX to go public to invest. 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