Apogee Therapeutics (APGE) Stock Price, News & Analysis

Company Overview

Apogee Therapeutics, Inc. (NASDAQ: APGE) is a clinical-stage biopharmaceutical company dedicated to the development of small-molecule therapies that modulate proteostasis pathways. The company’s research efforts are focused on identifying and advancing novel compounds capable of restoring or enhancing protein homeostasis in cells, with potential applications in oncology, autoimmune disorders and other diseases driven by dysregulated protein processing.

Apogee leverages a proprietary drug discovery platform that combines structure-based design, high-throughput screening and phenotypic assays to optimize lead candidates. Its pipeline includes multiple preclinical and early clinical-stage assets, each targeting distinct molecular mechanisms involved in cell signaling, protein folding and degradation pathways. The company collaborates with academic institutions and research organizations to accelerate the translation of laboratory findings into therapeutic opportunities.

Based in the United States, Apogee Therapeutics maintains a focused R&D infrastructure designed to support rapid proof-of-concept studies and strategic partnerships. Its management team comprises seasoned professionals with expertise in drug development, regulatory affairs and commercialization, positioning the company to achieve clinical milestones and pursue collaboration or licensing arrangements that can further advance its pipeline.

Key Stats

• Today's Range: $38.20 to $39.32
• 50-Day Range: $36.33 to $47.55
• 52-Week Range: $26.20 to $63.50
• Volume: 778,691 shs
• Average Volume: 610,863 shs
• Market Capitalization: $1.80 billion
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $99.00
• Consensus Rating: Buy

Apogee Therapeutics Stock Analysis - MarketRank™

Apogee Therapeutics scored higher than 62% of companies evaluated by MarketBeat, and ranked 412th out of 943 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.5 / 5
• Analyst Rating: Buy

Consensus Rating

Apogee Therapeutics has received a consensus rating of Buy. The company's average rating score is 3.00, and is based on 6 buy ratings, no hold ratings, and no sell ratings.

Amount of Analyst Coverage

Apogee Therapeutics has only been the subject of 4 research reports in the past 90 days.

Earnings and Valuation

• Score: 0.0 / 5
• Proj. Earnings Growth: Decreasing

Earnings Growth

Earnings for Apogee Therapeutics are expected to decrease in the coming year, from ($3.09) to ($3.67) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Apogee Therapeutics is -10.83, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Apogee Therapeutics is -10.83, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Apogee Therapeutics has a P/B Ratio of 2.45. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.

Short Interest

• Score: 3.0 / 5
• Short Interest Level: Healthy

Percentage of Shares Shorted

23.20% of the float of Apogee Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Apogee Therapeutics has a short interest ratio ("days to cover") of 9.7.

Change versus previous month

Short interest in Apogee Therapeutics has recently decreased by 5.66%, indicating that investor sentiment is improving significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Apogee Therapeutics does not currently pay a dividend.

Dividend Growth

Apogee Therapeutics does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

23.20% of the float of Apogee Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Apogee Therapeutics has a short interest ratio ("days to cover") of 9.7.

Change versus previous month

Short interest in Apogee Therapeutics has recently decreased by 5.66%, indicating that investor sentiment is improving significantly.

News and Social Media

• Score: 2.5 / 5
• News Sentiment: 0.58

News Sentiment

Apogee Therapeutics has a news sentiment score of 0.58. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.96 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 5 news articles for Apogee Therapeutics this week, compared to 4 articles on an average week.

Search Interest

7 people have searched for APGE on MarketBeat in the last 30 days.

Company Ownership

• Score: 4.2 / 5
• Insider Trading: Selling Shares

Insider Buying vs. Insider Selling

In the past three months, Apogee Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $653,093.00 in company stock.

Percentage Held by Insiders

42.77% of the stock of Apogee Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.

Percentage Held by Institutions

79.04% of the stock of Apogee Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

APGE Stock Analysis - Frequently Asked Questions

How have APGE shares performed this year?

Apogee Therapeutics' stock was trading at $45.30 at the beginning of the year. Since then, APGE stock has decreased by 13.9% and is now trading at $39.00.

How were Apogee Therapeutics' earnings last quarter?

Apogee Therapeutics Inc. (NASDAQ:APGE) issued its earnings results on Monday, May, 12th. The company reported ($0.95) earnings per share (EPS) for the quarter, beating the consensus estimate of ($1.19) by $0.24.

When did Apogee Therapeutics IPO?

Apogee Therapeutics (APGE) raised $282 million in an initial public offering (IPO) on Friday, July 14th 2023. The company issued 17,650,000 shares at $15.00-$17.00 per share.

How do I buy shares of Apogee Therapeutics?

Shares of APGE stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Apogee Therapeutics own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Apogee Therapeutics investors own include NVIDIA (NVDA), Meta Platforms (META), Advanced Micro Devices (AMD), Broadcom (AVGO), Palo Alto Networks (PANW), Netflix (NFLX) and Invesco QQQ (QQQ).

Company Calendar

• Last Earnings: 5/12/2025
• Today: 7/17/2025
• Next Earnings (Estimated): 8/11/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:APGE
• CIK: 1974640
• Web: www.apogeetherapeutics.com
• Phone: 650-394-5230
• Fax: N/A
• Employees: 91
• Year Founded: N/A

Price Target and Rating

• Average Price Target for Apogee Therapeutics: $99.00
• High Price Target: $116.00
• Low Price Target: $89.00
• Potential Upside/Downside: +158.0%
• Consensus Rating: Buy
• Rating Score (0-4): 3.00
• Research Coverage: 6 Analysts

Profitability

• EPS (Trailing Twelve Months): ($3.60)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$182.15 million
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: -28.35%
• Return on Assets: -26.98%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 15.82
• Quick Ratio: 15.82

Sales & Book Value

• Annual Sales: N/A
• Price / Sales: N/A
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $15.92 per share
• Price / Book: 2.41

Miscellaneous

• Outstanding Shares: 46,050,000
• Free Float: 26,353,000
• Market Cap: $1.77 billion
• Optionable: Optionable
• Beta: 1.47