Opthea (OPT) Stock Price, News & Analysis

Company Overview

Opthea Limited (NASDAQ: OPT) is a clinical-stage biotechnology company focused on the discovery and development of targeted therapies for retinal vascular diseases. Headquartered in Melbourne, Australia, with additional offices in the United States, Opthea is advancing novel biologics designed to address significant unmet needs in ophthalmology. The company’s primary asset, OPT-302, is a next-generation anti-VEGF-C/D therapy being evaluated as a potential complement to existing anti-VEGF-A treatments for wet age-related macular degeneration (AMD) and diabetic macular edema (DME).

Founded in 2012, Opthea has built a robust pipeline by leveraging insights into vascular endothelial growth factors and their role in retinal diseases. OPT-302’s unique mechanism of action aims to inhibit compensatory pathways that can limit the effectiveness of current therapies, with the goal of improving visual outcomes for patients. The company has advanced its lead program through Phase 2 clinical trials and is now progressing late-stage studies in partnership with leading ophthalmology research centers in North America, Europe and Asia Pacific.

Opthea’s global footprint includes collaborative relationships with academic institutions and contract research organizations to support its clinical development efforts. The company is also exploring potential strategic alliances to facilitate broader commercialization and to expand the application of its novel biologics in additional ocular indications. By focusing on precision-targeted mechanisms, Opthea seeks to become a leader in next-generation treatments for blinding eye disorders.

The company is led by an experienced management team with deep expertise in biopharmaceutical research, development and commercialization. Christiana Stamoulis serves as Chief Executive Officer and Managing Director, bringing extensive industry experience in ophthalmology drug development and global product launches. Under her leadership, Opthea continues to advance its mission to deliver innovative therapies that can transform the standard of care for patients suffering from retinal vascular diseases.

Key Stats

• Today's Range: $3.25 to $3.48
• 50-Day Range: $3.41 to $3.41
• 52-Week Range: $1.90 to $6.30
• Volume: 3,000 shs
• Average Volume: 26,647 shs
• Market Capitalization: $524.83 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $1.33
• Consensus Rating: Hold

Opthea Stock Analysis - MarketRank™

Opthea scored higher than 8% of companies evaluated by MarketBeat, and ranked 893rd out of 929 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 1.1 / 5
• Analyst Rating: Hold

Consensus Rating

Opthea has received a consensus rating of Hold. The company's average rating score is 2.17, and is based on no buy ratings, 4 hold ratings, and 1 sell rating.

Amount of Analyst Coverage

Opthea has received no research coverage in the past 90 days.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for Opthea are expected to grow in the coming year, from ($1.39) to ($0.67) per share.

Short Interest

• Score: N/A
• Short Interest Level: N/A

Short Interest

There is no current short interest data available for OPT.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Opthea does not currently pay a dividend.

Dividend Growth

Opthea does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Short Interest

There is no current short interest data available for OPT.

News and Social Media

• Score: 2.2 / 5
• News Sentiment: 0.92

News Sentiment

Opthea has a news sentiment score of 0.92. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.57 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 3 news articles for Opthea this week, compared to 3 articles on an average week.

Company Ownership

• Score: 0.8 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, Opthea insiders have not sold or bought any company stock.

Percentage Held by Insiders

Only 3.20% of the stock of Opthea is held by insiders.

Percentage Held by Institutions

55.95% of the stock of Opthea is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

OPT Stock Analysis - Frequently Asked Questions

How have OPT shares performed this year?

Opthea's stock was trading at $3.93 at the beginning of 2025. Since then, OPT stock has decreased by 13.2% and is now trading at $3.41.

When did Opthea IPO?

Opthea (OPT) raised $161 million in an initial public offering (IPO) on Friday, October 16th 2020. The company issued 9,300,000 shares at a price of $17.26 per share. Citigroup and SVB Leerink served as the underwriters for the IPO and Oppenheimer & Co. and Truist Securities were co-managers.

How do I buy shares of Opthea?

Shares of OPT stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Opthea own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Opthea investors own include PayPal (PYPL), Sunrun (RUN), Avino Silver & Gold Mines (ASM), QUALCOMM (QCOM), Ross Stores (ROST), Zendesk (ZEN) and Adobe (ADBE).

Company Calendar

• Today: 7/05/2025
• Next Earnings (Estimated): 8/28/2025
• Fiscal Year End: 6/30/2026

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:OPT
• CIK: 1815620
• Web: www.opthea.com
• Phone: 61-3-9826-0399
• Fax: N/A
• Employees: 8
• Year Founded: N/A

Price Target and Rating

• Average Stock Price Target: $1.33
• High Stock Price Target: $2.00
• Low Stock Price Target: $1.00
• Potential Upside/Downside: -60.9%
• Consensus Rating: Hold
• Rating Score (0-4): 2.17
• Research Coverage: 6 Analysts

Profitability

• EPS (Trailing Twelve Months): N/A
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: N/A
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: N/A
• Return on Assets: N/A

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 1.57
• Quick Ratio: N/A

Sales & Book Value

• Annual Sales: $120 thousand
• Price / Sales: 4,373.61
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: ($0.56) per share
• Price / Book: -6.09

Miscellaneous

• Outstanding Shares: 153,910,000
• Free Float: 148,986,000
• Market Cap: $524.83 million
• Optionable: Not Optionable
• Beta: 1.17