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Opthea (OPT) Competitors

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OPT vs. TYRA, AUPH, STOK, ZYME, and OCUL

Should you be buying Opthea stock or one of its competitors? The main competitors of Opthea include Tyra Biosciences (TYRA), Aurinia Pharmaceuticals (AUPH), Stoke Therapeutics (STOK), Zymeworks (ZYME), and Ocular Therapeutix (OCUL). These companies are all part of the "pharmaceutical products" industry.

How does Opthea compare to Tyra Biosciences?

Tyra Biosciences (NASDAQ:TYRA) and Opthea (NASDAQ:OPT) are both medical companies, but which is the better business? We will contrast the two businesses based on the strength of their profitability, earnings, risk, dividends, analyst recommendations, media sentiment, institutional ownership and valuation.

Opthea's return on equity of 0.00% beat Tyra Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Tyra BiosciencesN/A -41.17% -38.40%
Opthea N/A N/A N/A

Tyra Biosciences has higher earnings, but lower revenue than Opthea.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Tyra BiosciencesN/AN/A-$119.95M-$2.01N/A
Opthea$25K20,993.46-$162.79MN/AN/A

84.1% of Tyra Biosciences shares are held by institutional investors. Comparatively, 56.0% of Opthea shares are held by institutional investors. 12.5% of Tyra Biosciences shares are held by insiders. Comparatively, 3.2% of Opthea shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

In the previous week, Tyra Biosciences had 1 more articles in the media than Opthea. MarketBeat recorded 1 mentions for Tyra Biosciences and 0 mentions for Opthea. Tyra Biosciences' average media sentiment score of 0.00 beat Opthea's score of -0.54 indicating that Tyra Biosciences is being referred to more favorably in the media.

Company Overall Sentiment
Tyra Biosciences Neutral
Opthea Negative

Tyra Biosciences has a beta of 0.79, suggesting that its share price is 21% less volatile than the S&P 500. Comparatively, Opthea has a beta of 1.12, suggesting that its share price is 12% more volatile than the S&P 500.

Tyra Biosciences presently has a consensus target price of $46.50, indicating a potential upside of 37.26%. Given Tyra Biosciences' stronger consensus rating and higher probable upside, equities research analysts clearly believe Tyra Biosciences is more favorable than Opthea.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Tyra Biosciences
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.92
Opthea
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

Summary

Tyra Biosciences beats Opthea on 9 of the 13 factors compared between the two stocks.

How does Opthea compare to Aurinia Pharmaceuticals?

Aurinia Pharmaceuticals (NASDAQ:AUPH) and Opthea (NASDAQ:OPT) are both medical companies, but which is the better business? We will contrast the two companies based on the strength of their media sentiment, risk, profitability, earnings, dividends, analyst recommendations, valuation and institutional ownership.

36.8% of Aurinia Pharmaceuticals shares are owned by institutional investors. Comparatively, 56.0% of Opthea shares are owned by institutional investors. 12.2% of Aurinia Pharmaceuticals shares are owned by insiders. Comparatively, 3.2% of Opthea shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Aurinia Pharmaceuticals has higher revenue and earnings than Opthea.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aurinia Pharmaceuticals$283.05M7.45$287.20M$2.087.80
Opthea$25K20,993.46-$162.79MN/AN/A

In the previous week, Aurinia Pharmaceuticals had 4 more articles in the media than Opthea. MarketBeat recorded 4 mentions for Aurinia Pharmaceuticals and 0 mentions for Opthea. Aurinia Pharmaceuticals' average media sentiment score of 0.82 beat Opthea's score of -0.54 indicating that Aurinia Pharmaceuticals is being referred to more favorably in the media.

Company Overall Sentiment
Aurinia Pharmaceuticals Positive
Opthea Negative

Aurinia Pharmaceuticals has a beta of 1.44, suggesting that its stock price is 44% more volatile than the S&P 500. Comparatively, Opthea has a beta of 1.12, suggesting that its stock price is 12% more volatile than the S&P 500.

Aurinia Pharmaceuticals has a net margin of 101.46% compared to Opthea's net margin of 0.00%. Aurinia Pharmaceuticals' return on equity of 27.47% beat Opthea's return on equity.

Company Net Margins Return on Equity Return on Assets
Aurinia Pharmaceuticals101.46% 27.47% 19.61%
Opthea N/A N/A N/A

Aurinia Pharmaceuticals currently has a consensus price target of $17.25, indicating a potential upside of 6.33%. Given Aurinia Pharmaceuticals' stronger consensus rating and higher probable upside, equities research analysts clearly believe Aurinia Pharmaceuticals is more favorable than Opthea.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aurinia Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.50
Opthea
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

Summary

Aurinia Pharmaceuticals beats Opthea on 12 of the 14 factors compared between the two stocks.

How does Opthea compare to Stoke Therapeutics?

Stoke Therapeutics (NASDAQ:STOK) and Opthea (NASDAQ:OPT) are both medical companies, but which is the better business? We will contrast the two companies based on the strength of their media sentiment, risk, profitability, earnings, dividends, analyst recommendations, valuation and institutional ownership.

Opthea has a net margin of 0.00% compared to Stoke Therapeutics' net margin of -3.73%. Opthea's return on equity of 0.00% beat Stoke Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Stoke Therapeutics-3.73% -2.05% -1.75%
Opthea N/A N/A N/A

Stoke Therapeutics currently has a consensus price target of $41.83, indicating a potential upside of 26.14%. Given Stoke Therapeutics' stronger consensus rating and higher probable upside, equities research analysts clearly believe Stoke Therapeutics is more favorable than Opthea.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Stoke Therapeutics
0 Sell rating(s)
2 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.92
Opthea
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

Stoke Therapeutics has a beta of 1.2, suggesting that its stock price is 20% more volatile than the S&P 500. Comparatively, Opthea has a beta of 1.12, suggesting that its stock price is 12% more volatile than the S&P 500.

Stoke Therapeutics has higher revenue and earnings than Opthea.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Stoke Therapeutics$184.42M11.20-$6.89M-$0.12N/A
Opthea$25K20,993.46-$162.79MN/AN/A

In the previous week, Stoke Therapeutics had 5 more articles in the media than Opthea. MarketBeat recorded 5 mentions for Stoke Therapeutics and 0 mentions for Opthea. Stoke Therapeutics' average media sentiment score of 0.83 beat Opthea's score of -0.54 indicating that Stoke Therapeutics is being referred to more favorably in the media.

Company Overall Sentiment
Stoke Therapeutics Positive
Opthea Negative

56.0% of Opthea shares are owned by institutional investors. 9.5% of Stoke Therapeutics shares are owned by insiders. Comparatively, 3.2% of Opthea shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Summary

Stoke Therapeutics beats Opthea on 10 of the 15 factors compared between the two stocks.

How does Opthea compare to Zymeworks?

Opthea (NASDAQ:OPT) and Zymeworks (NASDAQ:ZYME) are both pharmaceutical products companies, but which is the superior stock? We will compare the two companies based on the strength of their profitability, media sentiment, valuation, earnings, analyst recommendations, dividends, institutional ownership and risk.

Zymeworks has higher revenue and earnings than Opthea.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Opthea$25K20,993.46-$162.79MN/AN/A
Zymeworks$105.96M19.06-$81.13M-$1.08N/A

Zymeworks has a consensus target price of $37.89, indicating a potential upside of 38.39%. Given Zymeworks' stronger consensus rating and higher possible upside, analysts clearly believe Zymeworks is more favorable than Opthea.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Opthea
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
9 Buy rating(s)
2 Strong Buy rating(s)
2.92

In the previous week, Zymeworks had 3 more articles in the media than Opthea. MarketBeat recorded 3 mentions for Zymeworks and 0 mentions for Opthea. Zymeworks' average media sentiment score of 0.56 beat Opthea's score of -0.54 indicating that Zymeworks is being referred to more favorably in the news media.

Company Overall Sentiment
Opthea Negative
Zymeworks Positive

Opthea has a beta of 1.12, suggesting that its share price is 12% more volatile than the S&P 500. Comparatively, Zymeworks has a beta of 1.2, suggesting that its share price is 20% more volatile than the S&P 500.

Opthea has a net margin of 0.00% compared to Zymeworks' net margin of -76.56%. Opthea's return on equity of 0.00% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
OptheaN/A N/A N/A
Zymeworks -76.56%-26.00%-20.57%

56.0% of Opthea shares are owned by institutional investors. Comparatively, 92.9% of Zymeworks shares are owned by institutional investors. 3.2% of Opthea shares are owned by insiders. Comparatively, 33.5% of Zymeworks shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Summary

Zymeworks beats Opthea on 11 of the 15 factors compared between the two stocks.

How does Opthea compare to Ocular Therapeutix?

Ocular Therapeutix (NASDAQ:OCUL) and Opthea (NASDAQ:OPT) are both medical companies, but which is the better business? We will compare the two businesses based on the strength of their earnings, valuation, media sentiment, dividends, profitability, analyst recommendations, institutional ownership and risk.

Opthea has a net margin of 0.00% compared to Ocular Therapeutix's net margin of -511.90%. Opthea's return on equity of 0.00% beat Ocular Therapeutix's return on equity.

Company Net Margins Return on Equity Return on Assets
Ocular Therapeutix-511.90% -70.68% -50.53%
Opthea N/A N/A N/A

Opthea has lower revenue, but higher earnings than Ocular Therapeutix.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ocular Therapeutix$51.95M41.44-$265.94M-$1.44N/A
Opthea$25K20,993.46-$162.79MN/AN/A

Ocular Therapeutix has a beta of 0.93, suggesting that its share price is 7% less volatile than the S&P 500. Comparatively, Opthea has a beta of 1.12, suggesting that its share price is 12% more volatile than the S&P 500.

59.2% of Ocular Therapeutix shares are held by institutional investors. Comparatively, 56.0% of Opthea shares are held by institutional investors. 2.3% of Ocular Therapeutix shares are held by insiders. Comparatively, 3.2% of Opthea shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

In the previous week, Ocular Therapeutix had 15 more articles in the media than Opthea. MarketBeat recorded 15 mentions for Ocular Therapeutix and 0 mentions for Opthea. Ocular Therapeutix's average media sentiment score of -0.06 beat Opthea's score of -0.54 indicating that Ocular Therapeutix is being referred to more favorably in the media.

Company Overall Sentiment
Ocular Therapeutix Neutral
Opthea Negative

Ocular Therapeutix presently has a consensus target price of $23.78, indicating a potential upside of 141.77%. Given Ocular Therapeutix's stronger consensus rating and higher probable upside, analysts clearly believe Ocular Therapeutix is more favorable than Opthea.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ocular Therapeutix
1 Sell rating(s)
1 Hold rating(s)
12 Buy rating(s)
0 Strong Buy rating(s)
2.79
Opthea
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

Summary

Ocular Therapeutix and Opthea tied by winning 7 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding OPT and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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OPT vs. The Competition

MetricOptheaMED IndustryMedical SectorNASDAQ Exchange
Market Cap$524.84M$3.42B$6.28B$12.10B
Dividend YieldN/A2.23%2.74%5.26%
P/E RatioN/A39.1229.2527.31
Price / Sales20,993.46291.95490.8175.98
Price / CashN/A125.0643.3053.90
Price / Book-2.607.149.766.74
Net Income-$162.79M$23.57M$3.55B$332.77M

Opthea Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
OPT
Opthea
N/A$3.41
flat
N/AN/A$524.84M$25KN/A8
TYRA
Tyra Biosciences
2.6132 of 5 stars
$35.06
-5.0%
$46.50
+32.6%
+223.1%$2.09BN/AN/A20
AUPH
Aurinia Pharmaceuticals
2.772 of 5 stars
$16.04
-2.0%
$17.25
+7.5%
+94.2%$2.08B$283.05M7.71300
STOK
Stoke Therapeutics
2.8588 of 5 stars
$33.33
-1.1%
$41.83
+25.5%
+239.8%$2.08B$184.42MN/A100
ZYME
Zymeworks
2.525 of 5 stars
$27.94
-2.2%
$37.89
+35.6%
N/A$2.06B$105.96MN/A460

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This page (NASDAQ:OPT) was last updated on 5/6/2026 by MarketBeat.com Staff.
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