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Best Penny Stocks Under 50 Cents Right Now

It can be difficult to find a deal in the stock market regardless of current market conditions. For the last decade, stocks have traded well above historical average P/E ratios. Fortunately there are still a handful of undervalued stocks in corners of the market that most investors ignore. These penny stocks all have a super-low share price of $0.50 or less and are sorted by average trading volume in dollars. These companies are considered the most actively-traded stocks priced under $0.50.

Tilray stock logo

1. Tilray NASDAQ:TLRY

$0.41 +0.01 (+2.17%)
As of 06/4/2025 04:00 PM Eastern

Tilray, Inc engages in the research, cultivation, processing, and distribution of medical cannabis. The company offers its products in Argentina, Australia, Canada, Chile, Croatia, Cyprus, the Czech Republic, Germany, New Zealand, and South Africa. More about Tilray

Market Capitalization
$411.76 million
P/E Ratio
-1.36
Consensus Rating
Hold
Consensus Price Target
$1.92 (+368.5% Upside)
Volume
29.78 million shares
Average Volume
28.59 million shares
Sangamo Therapeutics stock logo

2. Sangamo Therapeutics NASDAQ:SGMO

$0.49 -0.01 (-1.64%)
As of 06/4/2025 04:00 PM Eastern

Sangamo Therapeutics, Inc, a clinical-stage genomic medicine company, focuses on translating science into medicines that transform the lives of patients and families afflicted with serious diseases in the United States. More about Sangamo Therapeutics

Market Capitalization
$114.72 million
P/E Ratio
-0.66
Consensus Rating
Moderate Buy
Consensus Price Target
$4.50 (+814.6% Upside)
Volume
3.20 million shares
Average Volume
8.77 million shares
WW International stock logo

3. WW International NASDAQ:WW

$0.25 -0.03 (-10.51%)
As of 05/15/2025

WW International, Inc provides weight management products and services worldwide. It offers a range of nutritional, activity, behavioral, and lifestyle tools and approaches products and services. More about WW International

Market Capitalization
$20.04 million
P/E Ratio
-0.04
Consensus Rating
Hold
Consensus Price Target
$2.25 (+801.4% Upside)
Volume
10.45 million shares
Average Volume
10.83 million shares
Sunnova Energy International stock logo

4. Sunnova Energy International NYSE:NOVA

$0.20 -0.01 (-3.49%)
As of 06/4/2025 03:58 PM Eastern

Sunnova Energy International Inc engages in the provision of energy as a service in the United States. The company offers electricity, as well as offers operations and maintenance, monitoring, repairs and replacements, equipment upgrades, on-site power optimization, and solar energy system and energy storage system diagnostics services. More about Sunnova Energy International

Market Capitalization
$25.35 million
P/E Ratio
-0.06
Consensus Rating
Hold
Consensus Price Target
$4.36 (+2,060.2% Upside)
Volume
4.83 million shares
Average Volume
10.92 million shares
Plus Therapeutics stock logo

5. Plus Therapeutics NASDAQ:PSTV

$0.35 -0.03 (-6.91%)
As of 06/4/2025 04:00 PM Eastern

Plus Therapeutics, Inc, a clinical-stage pharmaceutical company, focuses on the development, manufacture, and commercialization of treatments for patients with cancer. More about Plus Therapeutics

Market Capitalization
$6.00 million
P/E Ratio
-0.14
Consensus Rating
Moderate Buy
Consensus Price Target
$11.50 (+3,160.6% Upside)
Volume
4.56 million shares
Average Volume
5.25 million shares
Nikola stock logo

6. Nikola NASDAQ:NKLA

$0.18 -0.07 (-28.74%)
Closing price 02/25/2025
Extended Trading
$0.18 0.00 (0.00%)
As of 02/25/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Nikola Corporation operates as a technology innovator and integrator that develops energy and transportation solutions in the United States and internationally. More about Nikola

Market Capitalization
$11.14 million
P/E Ratio
-0.01
Consensus Rating
Hold
Consensus Price Target
$6.00 (+3,178.7% Upside)
Volume
36.66 million shares
Average Volume
9.57 million shares
Cellectar Biosciences stock logo

7. Cellectar Biosciences NASDAQ:CLRB

$0.46 +0.18 (+66.32%)
As of 06/4/2025 04:00 PM Eastern

Cellectar Biosciences, Inc, a clinical biopharmaceutical company, focuses on the discovery, development, and commercialization of drugs for the treatment of cancer. More about Cellectar Biosciences

Market Capitalization
$21.28 million
P/E Ratio
-0.27
Consensus Rating
Hold
Consensus Price Target
$12.50 (+2,607.4% Upside)
Volume
623.93 million shares
Average Volume
3.67 million shares
EON Resources stock logo

8. EON Resources NYSEAMERICAN:EONR

$0.43 +0.04 (+10.97%)
As of 06/4/2025 04:10 PM Eastern

EON Resources Inc, an independent oil and natural gas company, focuses on the acquisition, development, exploration, and production of oil and natural gas properties in the Permian Basin. More about EON Resources

Consensus Rating
Buy
Consensus Price Target
$2.00 (+365.1% Upside)
Volume
2.40 million shares
Average Volume
3.21 million shares
Today's Range
$0.37
$0.44
50-Day Range
$0.35
$0.53
GlycoMimetics stock logo

9. GlycoMimetics NASDAQ:GLYC

$0.21 +0.00 (+0.48%)
As of 06/4/2025 04:00 PM Eastern

GlycoMimetics, Inc, a biotechnology company, focuses on the discovery and development of therapies for cancers and inflammatory diseases in the United States. More about GlycoMimetics

Market Capitalization
$13.55 million
P/E Ratio
-0.46
Consensus Rating
Moderate Buy
Volume
302,013 shares
Average Volume
6.42 million shares
Today's Range
$0.20
$0.22
Applied Therapeutics stock logo

10. Applied Therapeutics NASDAQ:APLT

$0.38 +0.02 (+5.45%)
As of 06/4/2025 04:00 PM Eastern

Applied Therapeutics, Inc, a clinical-stage biopharmaceutical company, engages in the development of a pipeline of novel product candidates against validated molecular targets in indications of high unmet medical need in the United States. More about Applied Therapeutics

Market Capitalization
$53.15 million
P/E Ratio
-0.23
Consensus Rating
Moderate Buy
Consensus Price Target
$6.10 (+1,524.9% Upside)
Volume
1.25 million shares
Average Volume
3.36 million shares
Harvard Bioscience stock logo

11. Harvard Bioscience NASDAQ:HBIO

$0.41 -0.01 (-2.56%)
As of 06/4/2025 04:00 PM Eastern

Harvard Bioscience, Inc develops, manufactures, and sells technologies, products, and services for life science applications in the United States and internationally. More about Harvard Bioscience

Market Capitalization
$18.14 million
P/E Ratio
-1.24
Consensus Rating
Moderate Buy
Consensus Price Target
$3.00 (+631.2% Upside)
Volume
3.58 million shares
Average Volume
2.98 million shares
Brand Engagement Network stock logo

12. Brand Engagement Network NASDAQ:BNAI

$0.43 +0.02 (+3.83%)
As of 06/4/2025 04:00 PM Eastern

Brand Engagement Network, Inc provides conversational AI assistants. The company offers security-focused, multimodal communication, and human-like assistants. More about Brand Engagement Network

Market Capitalization
$18.33 million
Consensus Rating
Buy
Consensus Price Target
$6.00 (+1,283.8% Upside)
Volume
4.55 million shares
Average Volume
2.77 million shares
Today's Range
$0.39
$0.47
Abpro stock logo

13. Abpro NASDAQ:ABP

$0.21 0.00 (-1.31%)
As of 06/4/2025 04:00 PM Eastern

Abpro Holdings Inc is a biotechnology company. The company's mission is to improve the lives of mankind facing severe and life-threatening diseases with next-generation antibody therapies. More about Abpro

Market Capitalization
$12.84 million
Consensus Rating
Buy
Consensus Price Target
$4.00 (+1,793.9% Upside)
Volume
590,707 shares
Average Volume
5.56 million shares
Today's Range
$0.21
$0.22
Canoo stock logo

14. Canoo NASDAQ:GOEV

$0.34 -0.07 (-15.95%)
Closing price 01/28/2025
Extended Trading
$0.34 0.00 (0.00%)
As of 01/28/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Canoo Inc, a mobility technology company, designs, develops, markets, and manufactures electric vehicles for consumer, commercial fleet, government, and military customers in the United States. More about Canoo

Market Capitalization
$1.67 million
P/E Ratio
0.00
Consensus Rating
Hold
Consensus Price Target
$23.50 (+6,731.4% Upside)
Volume
6.24 million shares
Average Volume
3.34 million shares
Vaxart stock logo

15. Vaxart NASDAQ:VXRT

$0.40 -0.01 (-3.07%)
As of 06/4/2025 04:00 PM Eastern

Vaxart, Inc, a clinical-stage biotechnology company, discovers and develops oral recombinant protein vaccines based on its proprietary oral vaccine platform. More about Vaxart

Market Capitalization
$92.20 million
P/E Ratio
-0.99
Consensus Rating
Buy
Consensus Price Target
$3.00 (+642.6% Upside)
Volume
1.89 million shares
Average Volume
2.44 million shares
bioAffinity Technologies stock logo

16. bioAffinity Technologies NASDAQ:BIAF

$0.30 +0.02 (+7.22%)
As of 06/4/2025 04:00 PM Eastern

bioAffinity Technologies, Inc, a biotechnology company, engages in developing non-invasive diagnostic tests and targeted cancer therapeutics. More about bioAffinity Technologies

Market Capitalization
$8.47 million
P/E Ratio
-0.37
Consensus Rating
Hold
Consensus Price Target
$6.00 (+1,880.2% Upside)
Volume
1.36 million shares
Average Volume
3.21 million shares
Mersana Therapeutics stock logo

17. Mersana Therapeutics NASDAQ:MRSN

$0.37 +0.02 (+5.79%)
As of 06/4/2025 04:00 PM Eastern

Mersana Therapeutics, Inc, a clinical stage biopharmaceutical company, develops antibody drug conjugates (ADC) for cancer patients with unmet needs. More about Mersana Therapeutics

Market Capitalization
$45.99 million
P/E Ratio
-0.60
Consensus Rating
Buy
Consensus Price Target
$5.20 (+1,309.2% Upside)
Volume
1.21 million shares
Average Volume
2.60 million shares
Aethlon Medical stock logo

18. Aethlon Medical NASDAQ:AEMD

$0.37 +0.02 (+4.37%)
As of 06/4/2025 04:00 PM Eastern

Aethlon Medical, Inc, a medical therapeutic company, focuses on developing products to treat cancer and life-threatening infectious diseases in the United States. More about Aethlon Medical

Market Capitalization
$5.87 million
P/E Ratio
-0.23
Consensus Rating
Buy
Consensus Price Target
$7.00 (+1,815.7% Upside)
Volume
99,061 shares
Average Volume
2.27 million shares
Cognition Therapeutics stock logo

19. Cognition Therapeutics NASDAQ:CGTX

$0.31 0.00 (-0.74%)
As of 06/4/2025 04:00 PM Eastern

Cognition Therapeutics, Inc, a clinical-stage biopharmaceutical company, engages in the discovery and development of small molecule therapeutics targeting age-related degenerative diseases and disorders of the central nervous system and retina. More about Cognition Therapeutics

Market Capitalization
$19.07 million
P/E Ratio
-0.32
Consensus Rating
Buy
Consensus Price Target
$5.63 (+1,728.7% Upside)
Volume
647,727 shares
Average Volume
2.66 million shares
Affimed stock logo

20. Affimed NASDAQ:AFMD

$0.18 -0.10 (-34.95%)
As of 05/19/2025

Affimed N.V., a clinical-stage biopharmaceutical company, focuses on discovering and developing cancer immunotherapies in the United States and Germany. More about Affimed

Market Capitalization
$2.92 million
Consensus Rating
Hold
Consensus Price Target
$7.90 (+4,251.5% Upside)
Volume
22.99 million shares
Average Volume
4.24 million shares
Today's Range
$0.17
$0.24
LeddarTech stock logo

21. LeddarTech NASDAQ:LDTC

$0.34 +0.00 (+1.46%)
As of 06/4/2025 04:00 PM Eastern

LeddarTech Holdings Inc provides AI-based fusion and perception software solutions for advanced driver assistance solutions and autonomous driving applications in Canada. More about LeddarTech

Market Capitalization
$9.78 million
P/E Ratio
-0.11
Consensus Rating
Moderate Buy
Consensus Price Target
$3.00 (+782.6% Upside)
Volume
96,564 shares
Average Volume
2.11 million shares
Biodesix stock logo

22. Biodesix NASDAQ:BDSX

$0.30 0.00 (-1.46%)
As of 06/4/2025 04:00 PM Eastern

Biodesix, Inc operates as a data-driven diagnostic solutions company in the United States. The company offers blood-based lung tests, including Nodify XL2 and Nodify CDT tests, together marketed as part of Nodify Lung Nodule Risk Assessment testing strategy, to assess the risk of lung cancer and help in identifying the appropriate treatment pathway and help physicians in reclassifying risk of malignancy in patients with suspicious lung nodules. More about Biodesix

Market Capitalization
$43.41 million
P/E Ratio
-0.76
Consensus Rating
Moderate Buy
Consensus Price Target
$1.75 (+490.8% Upside)
Volume
1.20 million shares
Average Volume
2.33 million shares
Origin Materials stock logo

23. Origin Materials NASDAQ:ORGN

$0.48 +0.03 (+6.63%)
As of 06/4/2025 04:00 PM Eastern

Origin Materials, Inc, together with its subsidiaries, operates as a carbon-negative materials company. The company develops a proprietary biomass conversion platform to convert biomass, or plant-based carbon into building block chemicals chloromethylfurfural and hydrothermal carbon, as well as other oils and extractives and other co-products. More about Origin Materials

Market Capitalization
$71.66 million
P/E Ratio
-0.84
Consensus Rating
Sell
Consensus Price Target
$1.50 (+213.9% Upside)
Volume
611,044 shares
Average Volume
1.43 million shares
23andMe stock logo

24. 23andMe NASDAQ:ME

$0.50 -0.27 (-35.32%)
Closing price 03/28/2025
Extended Trading
$0.50 0.00 (0.00%)
As of 03/28/2025 08:00 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

23andMe Holding Co operates as a consumer genetics testing company. The company operates in two segments, Consumer & Research Services and Therapeutics. More about 23andMe

Market Capitalization
$13.36 million
P/E Ratio
-0.03
Consensus Rating
Sell
Volume
29.28 million shares
Average Volume
1.35 million shares
Today's Range
$0.60
$1.10
OrangeKloud Technology stock logo

25. OrangeKloud Technology NASDAQ:ORKT

$0.46 -0.01 (-1.50%)
As of 06/4/2025 03:58 PM Eastern

Orangekloud Technology, Inc is a holding company, which engages in providing information technology consulting services. Its digital transformation projects include the sales and consulting of Microsoft Dynamics ERP software licenses. More about OrangeKloud Technology

Market Capitalization
$10.86 million
Consensus Rating
Buy
Consensus Price Target
$5.00 (+975.3% Upside)
Volume
64,223 shares
Average Volume
1.43 million shares
Today's Range
$0.45
$0.48