Best Penny Stocks Under 50 Cents Right Now It can be difficult to find a deal in the stock market regardless of current market conditions. For the last decade, stocks have traded well above historical average P/E ratios. Fortunately there are still a handful of undervalued stocks in corners of the market that most investors ignore. These penny stocks all have a super-low share price of $0.50 or less and are sorted by average trading volume in dollars. These companies are considered the most actively-traded stocks priced under $0.50. OverviewStocks Under $0.05Stocks Under $0.10Stocks Under $0.25Stocks Under $0.50Stocks Under $1Stocks Under $2Stocks Under $3Stocks Under $5Stocks Under $10Stocks Under $20Stocks Under $30Stocks Under $50Stocks On Sale 1. Adaptimmune Therapeutics NASDAQ:ADAP$0.13 -0.01 (-7.14%) Closing price 04:00 PM EasternExtended Trading$0.13 +0.00 (+0.77%) As of 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Adaptimmune Therapeutics plc, a clinical-stage biopharmaceutical company, provides novel cell therapies primarily to cancer patients in the United States and the United Kingdom. More about Adaptimmune TherapeuticsMarket Capitalization$37.11 millionP/E Ratio-0.20Consensus RatingHoldConsensus Price Target$1.35 (+939.7% Upside)Volume22.69 million sharesAverage Volume138.00 million shares Get the Latest News and Ratings for Your StocksEnter your email address below to receive the latest headlines and analysts' recommendations for your stocks with our free daily email newsletter. 2. urban-gro NASDAQ:UGRO$0.41 -0.04 (-8.44%) Closing price 04:00 PM EasternExtended Trading$0.42 +0.01 (+2.67%) As of 07:58 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.urban-gro, Inc engages in the designing, engineering, building, and integrating complex environmental equipment systems for indoor controlled environment agriculture (CEA) cultivation and retail facilities in the United States, Canada, and Europe. More about urban-groMarket Capitalization$5.71 millionP/E Ratio-0.37Consensus RatingStrong BuyVolume284,945 sharesAverage Volume14.83 million sharesToday's Range$0.40▼$0.453. Carisma Therapeutics NASDAQ:CARM$0.27 -0.02 (-6.29%) Closing price 04:00 PM EasternExtended Trading$0.25 -0.02 (-8.39%) As of 07:38 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Carisma Therapeutics, Inc, a clinical-stage cell therapy company, focuses on discovering and developing immunotherapies to treat cancer and other serious diseases in the United States. More about Carisma TherapeuticsMarket Capitalization$12.22 millionP/E Ratio-0.18Consensus RatingModerate BuyConsensus Price Target$1.93 (+602.6% Upside)Volume1.28 million sharesAverage Volume21.44 million shares4. Co-Diagnostics NASDAQ:CODX$0.34 -0.03 (-7.05%) Closing price 04:00 PM EasternExtended Trading$0.34 0.00 (-1.16%) As of 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Co-Diagnostics, Inc, a molecular diagnostics company, develops, manufactures, and sells reagents used for diagnostic tests that function through the detection and/or analysis of nucleic acid molecules in the United States and internationally. More about Co-DiagnosticsMarket Capitalization$14.26 millionP/E Ratio-0.30Consensus RatingBuyConsensus Price Target$5.50 (+1,498.8% Upside)Volume1.67 million sharesAverage Volume14.27 million shares5. Senseonics NYSE:SENS$0.44 -0.01 (-1.51%) Closing price 04:00 PM EasternExtended Trading$0.44 +0.00 (+0.28%) As of 08:00 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Senseonics Holdings, Inc, a medical technology company, focuses on development and manufacturing of continuous glucose monitoring (CGM) systems for people with diabetes in the United States and internationally. More about SenseonicsMarket Capitalization$355.04 millionP/E Ratio-3.35Consensus RatingBuyConsensus Price Target$1.54 (+252.8% Upside)Volume3.98 million sharesAverage Volume7.83 million shares6. Actelis Networks NASDAQ:ASNS$0.37 -0.03 (-6.48%) Closing price 04:00 PM EasternExtended Trading$0.37 +0.00 (+0.70%) As of 07:51 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Actelis Networks, Inc engages in the design, development, manufacture, and marketing of cyber hardened, hybrid fiber, networking solutions for Internet of Things and telecommunication companies in North America, Europe, the Middle East, Israel, and the Asia Pacific. More about Actelis NetworksMarket Capitalization$4.96 millionP/E Ratio-0.47Consensus RatingBuyConsensus Price Target$5.00 (+1,253.5% Upside)Volume746,868 sharesAverage Volume9.10 million shares7. Reviva Pharmaceuticals NASDAQ:RVPH$0.37 +0.06 (+19.56%) Closing price 04:00 PM EasternExtended Trading$0.38 +0.02 (+4.18%) As of 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Reviva Pharmaceuticals Holdings, Inc, a biopharmaceutical company, discovers, develops, and commercializes next-generation therapeutics for diseases targeting unmet medical needs in the areas of central nervous system, respiratory, inflammatory, and cardiometabolic diseases. More about Reviva PharmaceuticalsMarket Capitalization$21.38 millionP/E Ratio-0.57Consensus RatingBuyConsensus Price Target$4.86 (+1,217.7% Upside)Volume26.30 million sharesAverage Volume5.43 million shares8. TNL Mediagene NASDAQ:TNMG$0.27 -0.01 (-2.25%) As of 03:59 PM EasternTNL Mediagene engages in digital advertising, integrated marketing, marketing survey, artificial intelligence technology, data analysis, content service platform, and production of audio-visual programs. More about TNL MediageneMarket Capitalization$7.10 millionConsensus RatingBuyConsensus Price Target$3.50 (+1,217.8% Upside)Volume1.44 million sharesAverage Volume6.38 million sharesToday's Range$0.26▼$0.289. Promis Neurosciences NASDAQ:PMN$0.42 -0.02 (-3.41%) Closing price 04:00 PM EasternExtended Trading$0.43 +0.00 (+0.24%) As of 07:33 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.ProMIS Neurosciences, Inc discovers and develops antibody therapies and therapeutic vaccines neurodegenerative diseases and other misfolded protein diseases in Canada. More about Promis NeurosciencesMarket Capitalization$23.68 millionP/E Ratio-2.02Consensus RatingBuyConsensus Price Target$4.33 (+919.6% Upside)Volume453,111 sharesAverage Volume3.27 million shares10. EON Resources NYSEAMERICAN:EONR$0.49 +0.04 (+8.86%) Closing price 04:10 PM EasternExtended Trading$0.48 0.00 (-0.55%) As of 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.EON Resources Inc, an independent oil and natural gas company, focuses on the acquisition, development, exploration, and production of oil and natural gas properties in the Permian Basin. More about EON ResourcesMarket Capitalization$16.71 millionConsensus RatingBuyConsensus Price Target$2.00 (+310.1% Upside)Volume5.72 million sharesAverage Volume2.45 million sharesToday's Range$0.45▼$0.5211. Abpro NASDAQ:ABP$0.22 -0.03 (-12.73%) As of 04:00 PM EasternAbpro Holdings Inc is a biotechnology company. The company's mission is to improve the lives of mankind facing severe and life-threatening diseases with next-generation antibody therapies. More about AbproMarket Capitalization$20.59 millionConsensus RatingBuyConsensus Price Target$4.00 (+1,684.1% Upside)Volume4.81 million sharesAverage Volume5.17 million sharesToday's Range$0.21▼$0.2512. IO Biotech NASDAQ:IOBT$0.36 0.00 (-0.55%) Closing price 04:00 PM EasternExtended Trading$0.36 +0.00 (+0.52%) As of 07:57 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.IO Biotech, Inc, a clinical-stage biopharmaceutical company, develops immune-modulating therapeutic cancer vaccines based on the T-win technology platform. More about IO BiotechP/E Ratio-0.23Consensus RatingHoldConsensus Price Target$8.00 (+2,103.2% Upside)Volume6.56 million sharesAverage Volume2.98 million sharesToday's Range$0.36▼$0.3813. Vaxart NASDAQ:VXRT$0.36 +0.00 (+0.77%) As of 03:59 PM EasternVaxart, Inc, a clinical-stage biotechnology company, discovers and develops oral recombinant protein vaccines based on its proprietary oral vaccine platform. More about VaxartMarket Capitalization$83.54 millionP/E Ratio-1.35Consensus RatingBuyConsensus Price Target$2.00 (+448.1% Upside)Volume728,149 sharesAverage Volume2.64 million shares14. Femasys NASDAQ:FEMY$0.35 +0.00 (+0.11%) Closing price 04:00 PM EasternExtended Trading$0.36 +0.00 (+0.74%) As of 07:50 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Femasys Inc, a biomedical company, develops therapeutic and diagnostic solutions to address unmet women healthcare needs worldwide. More about FemasysMarket Capitalization$11.47 millionP/E Ratio-0.41Consensus RatingBuyConsensus Price Target$7.33 (+1,981.0% Upside)Volume424,063 sharesAverage Volume2.08 million shares15. VYNE Therapeutics NASDAQ:VYNE$0.34 +0.01 (+1.82%) Closing price 04:00 PM EasternExtended Trading$0.33 0.00 (-0.90%) As of 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.VYNE Therapeutics Inc, a clinical-stage biopharmaceutical company, focuses on developing proprietary and therapeutics for the treatment of immuno-inflammatory conditions. More about VYNE TherapeuticsMarket Capitalization$8.38 millionP/E Ratio-0.37Consensus RatingHoldConsensus Price Target$6.25 (+1,765.7% Upside)Volume1.80 million sharesAverage Volume1.80 million shares16. ESSA Pharma NASDAQ:EPIX$0.19 0.00 (-1.24%) Closing price 04:00 PM EasternExtended Trading$0.20 +0.00 (+2.09%) As of 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.ESSA Pharma Inc, a clinical stage pharmaceutical company, focuses the development of small molecule drugs for the treatment of prostate cancer. More about ESSA PharmaMarket Capitalization$9.15 millionP/E Ratio-0.34Consensus RatingHoldConsensus Price Target$2.00 (+947.1% Upside)Volume5.00 million sharesAverage Volume3.06 million shares17. Heatwurx NASDAQ:PCSA$0.19 -0.01 (-3.86%) Closing price 04:00 PM EasternExtended Trading$0.19 +0.00 (+0.57%) As of 07:48 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Processa Pharmaceuticals, Inc, a clinical stage biopharmaceutical company, develops chemotherapy drugs to improve the safety and efficacy of cancer treatment. More about HeatwurxMarket Capitalization$10.05 millionP/E Ratio-0.08Consensus RatingModerate BuyConsensus Price Target$1.00 (+421.1% Upside)Volume2.01 million sharesAverage Volume2.67 million shares18. Ryvyl NASDAQ:RVYL$0.30 -0.01 (-1.82%) Closing price 04:00 PM EasternExtended Trading$0.53 +0.23 (+78.38%) As of 08:00 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Ryvyl Inc, a technology company, engages in the development, marketing, and sale of blockchain-based payment solutions in North America, Europe, and Asia. More about RyvylMarket Capitalization$9.58 millionP/E Ratio-0.03Consensus RatingHoldVolume35.00 million sharesAverage Volume1.61 million sharesToday's Range$0.29▼$0.3019. Harvard Bioscience NASDAQ:HBIO$0.44 0.00 (-0.30%) Closing price 04:00 PM EasternExtended Trading$0.45 +0.01 (+1.94%) As of 07:58 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Harvard Bioscience, Inc develops, manufactures, and sells technologies, products, and services for life science applications in the United States and internationally. More about Harvard BioscienceMarket Capitalization$19.58 millionP/E Ratio-0.34Consensus RatingModerate BuyConsensus Price Target$2.00 (+356.1% Upside)Volume396,575 sharesAverage Volume1.04 million shares20. Direct Digital NASDAQ:DRCT$0.34 +0.02 (+7.46%) Closing price 04:00 PM EasternExtended Trading$0.34 +0.01 (+1.95%) As of 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Direct Digital Holdings, Inc operates as an end-to-end full-service programmatic advertising platform. The company's platform primarily focuses on providing advertising technology, data-driven campaign optimization, and other solutions to underserved and less efficient markets on both the buy- and sell-side of the digital advertising ecosystem. More about Direct DigitalMarket Capitalization$7.09 millionP/E Ratio-0.18Consensus RatingModerate BuyConsensus Price Target$6.00 (+1,673.0% Upside)Volume4.92 million sharesAverage Volume1.23 million shares21. Leap Therapeutics NASDAQ:LPTX$0.45 +0.09 (+26.18%) Closing price 04:00 PM EasternExtended Trading$0.45 0.00 (-0.44%) As of 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Leap Therapeutics, Inc, a biopharmaceutical company, acquires and develops antibody therapies for the treatment of cancer. More about Leap TherapeuticsMarket Capitalization$14.91 millionP/E Ratio-0.29Consensus RatingHoldConsensus Price Target$3.38 (+643.4% Upside)Volume3.91 million sharesAverage Volume870,926 shares22. IGC Pharma NYSEMKT:IGC$0.41 +0.09 (+26.34%) Closing price 03:58 PM EasternExtended Trading$0.42 +0.00 (+0.73%) As of 07:56 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.IGC Pharma, Inc, a clinical stage pharmaceutical company, engages in developing treatments for Alzheimer's disease. The company's lead product is IGC-AD1, which is in a Phase 2B clinical trial as a treatment for agitation in dementia due to Alzheimer's; and TGR-63, IGC-1C, IGC-M3, and LMP in pre-clinical development. More about IGC PharmaMarket Capitalization$36.57 millionP/E Ratio-3.75Consensus RatingBuyConsensus Price Target$3.88 (+840.5% Upside)Volume214,616 sharesAverage Volume913,992 shares23. Argo Blockchain NASDAQ:ARBK$0.26 -0.01 (-4.38%) Closing price 04:00 PM EasternExtended Trading$0.26 +0.00 (+1.18%) As of 07:49 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Argo Blockchain plc, together with its subsidiaries, engages in the bitcoin and other cryptocurrencies mining business worldwide. More about Argo BlockchainMarket Capitalization$19.74 millionP/E Ratio-0.27Consensus RatingReduceVolume691,209 sharesAverage Volume1.40 million sharesToday's Range$0.26▼$0.2824. Windtree Therapeutics NASDAQ:WINT$0.07 0.00 (0.00%) As of 03:08 PM EasternWindtree Therapeutics, Inc, a biotechnology company, focuses on the development of therapeutics for the treatment of acute cardiovascular diseases. More about Windtree TherapeuticsMarket Capitalization$1.97 millionP/E Ratio0.00Consensus RatingHoldConsensus Price Target$350.00 (+519,959.4% Upside)Volume85,515 sharesAverage Volume5.17 million shares25. IGC Pharma NYSEAMERICAN:IGC$0.42 0.00 (-0.74%) As of 04:10 PM EasternIGC Pharma, Inc, a clinical stage biotechnology company, engages in developing cannabinoid-based formulations for treating diseases and conditions, including Alzheimer's disease, dysmenorrhea, premenstrual syndrome, and chronic pain. More about IGC PharmaMarket Capitalization$38.62 millionP/E Ratio-5.96Consensus RatingBuyConsensus Price Target$4.50 (+979.4% Upside)Volume752,071 sharesAverage Volume713,743 shares More Stock Ideas from MarketBeat Stock Lists 5G Stocks Biotech Stocks Blue Chip Stocks DOW 30 Stocks FAANG Stocks Gold Stocks Large Cap Stocks Lumber Stocks Marijuana Stocks Micro Cap Stocks Oil Stocks REITs Small Cap Stocks SPACs Travel Stocks Trillion Dollar Stocks Water Stocks Warren Buffett Stocks Low Priced Stocks Penny Stock List Popular Penny Stocks Top Stocks Today Stocks on Sale Stocks Under $0.05 Stocks Under $0.10 Stocks Under $0.25 Stocks Under $0.50 Stocks Under $1 Stocks Under $2 Stocks Under $3 Stocks Under $5 Stocks Under $10 Stocks Under $20 Stocks Under $30 Stocks Under $50 Stocks By Exchange NASDAQ Stocks NYSE Stocks NYSEAMERICAN Stocks NYSEARCA Stocks NYSEMKT Stocks OTCMKTS Stocks TSX Stocks TSXV Stocks LSE Stocks BATS Stocks Latest Stock Ideas Is Draganfly's Army Partnership a Game-Changer for Investors? 154% Jump in Bullish Bets: Is Ford About to Hit the Gas? 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