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Amylyx Pharmaceuticals (AMLX) Institutional Ownership

Amylyx Pharmaceuticals logo
$26.85 -0.63 (-2.29%)
Closing price 04:00 PM Eastern
Extended Trading
$27.58 +0.73 (+2.74%)
As of 07:59 PM Eastern
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Institutional Ownership Changes (13F Filings) for Amylyx Pharmaceuticals (NASDAQ:AMLX)

Current
Institutional Ownership
Percentage
95.84%
Number of
Institutional Buyers
(last 12 months)
112
Total
Institutional Inflows
(last 12 months)
$730.53M
Number of
Institutional Sellers
(last 12 months)
51
Total
Institutional Outflows
(last 12 months)
$204.95M
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AMLX Institutional Buying and Selling by Quarter

Amylyx Pharmaceuticals Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
10/9/2026GAMMA Investing LLC1,139$33K0.0%+163.0%0.001%
9/9/2026First Light Asset Management LLC3,023,256$54.30M3.3%-5.2%2.713%
9/9/2026Integrated Wealth Concepts LLC8,722$157K0.0%N/A0.008%
9/9/2026Maven Securities LTD25,000$449K0.0%-50.0%0.022%
9/8/2026Arizona State Retirement System19,825$356K0.0%+9.5%0.018%
8/27/2026Corient Private Wealth LP59,322$1.07M0.0%N/A0.053%
8/22/2026Seven Fleet Capital Management LP14,540$261K0.0%-12.8%0.013%
8/22/2026Premier Path Wealth Partners LLC18,265$328K0.0%-9.9%0.016%
8/20/2026Aldebaran Capital LLC195,892$3.52M2.6%-1.0%0.176%
8/20/2026Alyeska Investment Group L.P.1,053,015$18.91M0.0%N/A0.945%
8/19/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC173,407$3.11M0.0%+10.4%0.156%
8/19/2026Hsbc Holdings PLC14,554$269K0.0%+27.5%0.013%
8/19/2026Wellington Management Group LLP212,842$3.82M0.0%-11.9%0.191%
8/19/2026Nantahala Capital Management LLC486,684$8.74M0.0%N/A0.437%
8/17/2026Almitas Capital LLC974,881$17.51M4.2%N/A0.875%
8/17/2026Seven Fleet Capital Management LP14,540$261.14K0.0%N/A0.013%
8/17/2026Corient Private Wealth LP59,322$1.07M0.0%N/A0.053%
8/17/2026Bank of America Corp DE821,841$14.76M0.0%N/A0.738%
8/15/2026Jupiter Topco LLC5,236,102$94.01M0.0%N/A4.699%
8/15/2026Elmind Capital LP112,000$2.01M0.0%N/A0.101%
8/14/2026Hsbc Holdings PLC14,554$269K0.0%N/A0.013%
8/14/2026Canada Pension Plan Investment Board27,600$496K0.0%N/A0.025%
8/14/2026Parkman Healthcare Partners LLC398,782$7.16M0.7%N/A0.358%
8/14/2026Legal & General Group Plc56,477$1.01M0.0%N/A0.051%
8/14/2026The Manufacturers Life Insurance Company37,828$679K0.0%N/A0.034%
8/13/2026Connor Clark & Lunn Investment Management Ltd.721,002$12.95M0.0%N/A0.647%
8/10/2026Great Lakes Advisors LLC12,807$230K0.0%N/A0.011%
8/7/2026BlackRock Inc.8,827,085$158.53M0.0%N/A7.939%
8/7/2026Deutsche Bank AG557,937$10.02M0.0%N/A0.502%
8/6/2026Bank of New York Mellon Corp274,435$4.93M0.0%N/A0.247%
8/6/2026State of Wyoming2,223$40K0.0%N/A0.002%
8/6/2026GSA Capital Partners LLP39,241$705K0.0%N/A0.035%
6/4/2026Seven Fleet Capital Management LP16,671$232K0.1%+44.1%0.015%
5/19/2026Bank of America Corp DE1,330,689$18.50M0.0%-0.4%1.197%
5/19/2026Stempoint Capital LP669,685$9.31M1.8%+18.5%0.602%
5/19/2026Janus Henderson Group PLC4,986,073$69.26M0.0%+11.6%4.484%
5/18/2026ADAR1 Capital Management LLC1,000,604$13.91M0.8%+12.4%0.900%
5/18/2026Amundi12,895$179K0.0%N/A0.012%
5/18/2026California State Teachers Retirement System65,002$904K0.0%-17.8%0.058%
5/18/2026Royal Bank of Canada12,383$172K0.0%-20.8%0.011%
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5/16/2026The Manufacturers Life Insurance Company38,781$539K0.0%+43.7%0.035%
5/16/2026First Light Asset Management LLC3,190,645$44.35M4.0%-4.9%2.870%
5/16/2026SummitTX Capital L.P.227,010$3.16M0.1%+3.9%0.204%
5/14/2026Siren L.L.C.1,230,000$17.10M0.5%N/A1.106%
5/14/2026Sei Investments Co.85,279$1.19M0.0%+61.3%0.077%
5/7/2026Dimensional Fund Advisors LP903,192$12.54M0.0%+17.1%0.813%
5/7/2026KBC Group NV1,863$26K0.0%N/A0.002%
5/7/2026Swiss National Bank130,300$1.81M0.0%-19.4%0.117%
5/5/2026Bank of New York Mellon Corp251,104$3.49M0.0%+15.5%0.226%
4/30/2026Hsbc Holdings PLC11,414$157K0.0%N/A0.010%
4/24/2026iA Global Asset Management Inc.304,786$4.24M0.1%N/A0.276%
4/22/2026Pictet Asset Management Holding SA10,768$150K0.0%N/A0.010%
3/3/2026Caitong International Asset Management Co. Ltd3,859$47K0.0%+954.4%0.004%
2/26/2026Seven Fleet Capital Management LP11,571$140K0.1%N/A0.011%
2/19/2026T. Rowe Price Investment Management Inc.4,517$55K0.0%-99.6%0.004%
2/19/2026Invesco Ltd.175,914$2.13M0.0%-78.3%0.160%
2/18/2026ADAR1 Capital Management LLC890,356$10.76M0.8%+2.8%0.811%
2/18/2026XTX Topco Ltd189,673$2.29M0.1%N/A0.173%
2/18/2026Voloridge Investment Management LLC153,363$1.85M0.0%N/A0.140%
2/18/2026Virtus Investment Advisers LLC20,307$245K0.1%N/A0.018%
2/18/2026Wellington Management Group LLP225,782$2.73M0.0%-4.4%0.206%
2/18/2026SummitTX Capital L.P.218,399$2.64M0.1%+30.0%0.199%
2/18/2026Tudor Investment Corp ET AL22,402$271K0.0%N/A0.020%
2/18/2026Quadrature Capital Ltd15,465$187K0.0%-45.3%0.014%
2/18/2026Numerai GP LLC112,648$1.36M0.2%+67.7%0.103%
2/18/2026Perceptive Advisors LLC8,284,882$100.08M1.8%-7.5%7.544%
2/18/2026Millennium Management LLC46,455$561K0.0%-88.9%0.042%
2/18/2026Janus Henderson Group PLC4,465,872$53.99M0.0%+76.1%4.067%
2/18/2026Elmind Capital LP112,000$1.35M0.4%N/A0.102%
2/18/2026Engineers Gate Manager LP18,358$222K0.0%N/A0.017%
2/18/2026Commodore Capital LP5,650,000$68.25M4.5%+38.6%5.145%
2/18/2026Cormorant Asset Management LP400,000$4.83M0.2%-20.0%0.364%
2/18/2026Balyasny Asset Management L.P.858,684$10.37M0.0%-41.8%0.782%
2/18/2026683 Capital Management LLC1,650,000$19.93M0.9%-6.3%1.502%
2/18/2026ACT Capital Management LLC9,000$109K0.1%N/A0.008%
2/17/2026Logos Global Management LP950,000$11.48M0.7%-34.5%0.865%
2/17/2026ADAR1 Capital Management LLC890,356$10.76M0.8%+2.8%0.811%
2/17/2026Schonfeld Strategic Advisors LLC21,052$254K0.0%-51.8%0.019%
2/17/2026AQR Capital Management LLC27,847$336K0.0%-62.2%0.025%
2/17/2026Trexquant Investment LP48,112$581K0.0%-78.4%0.044%
2/17/2026Price T Rowe Associates Inc. MD107,548$1.30M0.0%+7.1%0.098%
2/17/2026Adage Capital Partners GP L.L.C.2,777,055$33.55M0.1%-59.3%2.529%
2/17/2026California State Teachers Retirement System79,090$955K0.0%+1,726.1%0.072%
2/17/2026Russell Investments Group Ltd.65,438$790K0.0%+18.1%0.060%
2/17/2026Atom Investors LP139,422$1.68M0.1%N/A0.127%
2/17/2026State of Wisconsin Investment Board84,144$1.02M0.0%+506.4%0.077%
2/17/2026Royal Bank of Canada15,643$188K0.0%-83.2%0.014%
2/17/2026Persistent Asset Partners Ltd31,147$376K0.2%+35.9%0.028%
2/16/2026Squarepoint Ops LLC76,562$925K0.0%N/A0.070%
2/16/2026Sofinnova Investments Inc.527,099$6.37M0.3%N/A0.480%
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2/16/2026Verition Fund Management LLC29,487$356K0.0%-53.9%0.027%
2/16/2026Mariner LLC46,342$560K0.0%-3.5%0.042%
2/16/2026Landscape Capital Management L.L.C.12,226$148K0.0%+17.5%0.011%
2/16/2026Barclays PLC295,177$3.57M0.0%-28.7%0.269%
2/13/2026Nantahala Capital Management LLC835,684$10.10M0.3%-10.7%0.761%
2/13/2026The Manufacturers Life Insurance Company 26,988$326K0.0%+13.4%0.025%
2/13/2026Alpha Wave Global LP317,678$3.84M0.5%-2.9%0.289%
2/13/2026Rafferty Asset Management LLC17,673$213K0.0%N/A0.016%
2/13/2026Headlands Technologies LLC30,543$369K0.0%N/A0.028%
2/13/2026Charles Schwab Investment Management Inc.712,990$8.61M0.0%+10.5%0.649%


AMLX Institutional Ownership - Frequently Asked Questions

During the previous two years, 181 institutional investors and hedge funds held shares of Amylyx Pharmaceuticals. The most heavily invested institutionals were BlackRock Inc. ($158.53M), Perceptive Advisors LLC ($100.08M), Jupiter Topco LLC ($94.01M), TCG Crossover Management LLC ($84.85M), Vanguard Group Inc. ($70.12M), Janus Henderson Group PLC ($69.26M), and Commodore Capital LP ($68.25M).Learn more on Amylyx Pharmaceuticals' institutional investors.

95.84% of Amylyx Pharmaceuticals' stock is owned by institutional investors. Learn more on AMLX's institutional investor holdings.

Of the 159 institutional investors that purchased Amylyx Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: BlackRock Inc. ($8.83M), Adage Capital Partners GP L.L.C. ($8.80M), Commodore Capital LP ($5.65M), Jupiter Topco LLC ($5.24M), First Light Asset Management LLC ($3.36M), Millennium Management LLC ($2.63M), and Janus Henderson Group PLC ($2.45M).

Institutional investors have bought a total of 48,442,812 shares in the last 24 months. This purchase volume represents approximately $730.53M in transactions.

Of the 51 institutional investors that sold Amylyx Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Adage Capital Partners GP L.L.C. ($4.04M), Nantahala Capital Management LLC ($2.10M), Millennium Management LLC ($1.47M), T. Rowe Price Investment Management Inc. ($1.19M), UBS Group AG ($861.15K), Perceptive Advisors LLC ($667.48K), and Invesco Ltd. ($634.73K).

Institutional investors have sold a total of 16,089,505 shares in the last 24 months. This volume of shares sold represents approximately $204.95M in transactions.


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Institutional ownership data for NASDAQ:AMLX is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 10/9/2026. New 13F filings are added each quarter as they're published.
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