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Amylyx Pharmaceuticals (AMLX) Institutional Ownership

Amylyx Pharmaceuticals logo
$34.49 +0.68 (+2.01%)
Closing price 09/2/2026 04:00 PM Eastern
Extended Trading
$34.88 +0.39 (+1.13%)
As of 09/2/2026 08:00 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Institutional Ownership Changes (13F Filings) for Amylyx Pharmaceuticals (NASDAQ:AMLX)

Current
Institutional Ownership
Percentage
95.84%
Number of
Institutional Buyers
(last 12 months)
110
Total
Institutional Inflows
(last 12 months)
$754.90M
Number of
Institutional Sellers
(last 12 months)
51
Total
Institutional Outflows
(last 12 months)
$201.59M
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AMLX Institutional Buying and Selling by Quarter

Amylyx Pharmaceuticals Major Shareholders & Ownership History

Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
8/27/2026 Corient Private Wealth LP59,322$1.07M0.0%N/A0.053%
8/24/2026 California State Teachers Retirement System1,434,501$25.76M0.0%+2,106.9%1.287%
8/22/2026 Seven Fleet Capital Management LP14,540$261K0.0%-12.8%0.013%
8/22/2026 Premier Path Wealth Partners LLC18,265$328K0.0%-9.9%0.016%
8/20/2026 Aldebaran Capital LLC195,892$3.52M2.6%-1.0%0.176%
8/20/2026 Alyeska Investment Group L.P.1,053,015$18.91M0.0%N/A0.945%
8/19/2026 UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC173,407$3.11M0.0%+10.4%0.156%
8/19/2026 Hsbc Holdings PLC14,554$269K0.0%+27.5%0.013%
8/19/2026 Wellington Management Group LLP212,842$3.82M0.0%-11.9%0.191%
8/19/2026 Nantahala Capital Management LLC486,684$8.74M0.0%N/A0.437%
8/17/2026 Almitas Capital LLC974,881$17.51M4.2%N/A0.875%
8/17/2026 Seven Fleet Capital Management LP14,540$261.14K0.0%N/A0.013%
8/17/2026 Corient Private Wealth LP59,322$1.07M0.0%N/A0.053%
8/17/2026 Bank of America Corp DE821,841$14.76M0.0%N/A0.738%
8/15/2026 Jupiter Topco LLC5,236,102$94.01M0.0%N/A4.699%
8/15/2026 Elmind Capital LP112,000$2.01M0.0%N/A0.101%
8/14/2026 Hsbc Holdings PLC14,554$269K0.0%N/A0.013%
8/14/2026 Canada Pension Plan Investment Board27,600$496K0.0%N/A0.025%
8/14/2026 Parkman Healthcare Partners LLC398,782$7.16M0.7%N/A0.358%
8/14/2026 Legal & General Group Plc56,477$1.01M0.0%N/A0.051%
8/14/2026 The Manufacturers Life Insurance Company 37,828$679K0.0%N/A0.034%
8/13/2026 Connor Clark & Lunn Investment Management Ltd.721,002$12.95M0.0%N/A0.647%
8/10/2026 Great Lakes Advisors LLC12,807$230K0.0%N/A0.011%
8/7/2026 BlackRock Inc.8,827,085$158.53M0.0%N/A7.939%
8/7/2026 Deutsche Bank AG557,937$10.02M0.0%N/A0.502%
8/6/2026 Bank of New York Mellon Corp274,435$4.93M0.0%N/A0.247%
8/6/2026 State of Wyoming2,223$40K0.0%N/A0.002%
8/6/2026 GSA Capital Partners LLP39,241$705K0.0%N/A0.035%
6/4/2026 Seven Fleet Capital Management LP16,671$232K0.1%+44.1%0.015%
5/19/2026 Bank of America Corp DE1,330,689$18.50M0.0%-0.4%1.197%
5/19/2026 Stempoint Capital LP669,685$9.31M1.8%+18.5%0.602%
5/19/2026Janus Henderson Group PLC4,986,073$69.26M0.0%+11.6%4.484%
5/18/2026 ADAR1 Capital Management LLC1,000,604$13.91M0.8%+12.4%0.900%
5/18/2026 Amundi12,895$179K0.0%N/A0.012%
5/18/2026 California State Teachers Retirement System65,002$904K0.0%-17.8%0.058%
5/18/2026 Royal Bank of Canada12,383$172K0.0%-20.8%0.011%
5/16/2026 The Manufacturers Life Insurance Company38,781$539K0.0%+43.7%0.035%
5/16/2026 First Light Asset Management LLC3,190,645$44.35M4.0%-4.9%2.870%
5/16/2026 SummitTX Capital L.P.227,010$3.16M0.1%+3.9%0.204%
5/14/2026 Siren L.L.C.1,230,000$17.10M0.5%N/A1.106%
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5/14/2026 Sei Investments Co.85,279$1.19M0.0%+61.3%0.077%
5/7/2026 Dimensional Fund Advisors LP903,192$12.54M0.0%+17.1%0.813%
5/7/2026 KBC Group NV1,863$26K0.0%N/A0.002%
5/7/2026 Swiss National Bank130,300$1.81M0.0%-19.4%0.117%
5/5/2026 Bank of New York Mellon Corp251,104$3.49M0.0%+15.5%0.226%
4/30/2026 Hsbc Holdings PLC11,414$157K0.0%N/A0.010%
4/24/2026 iA Global Asset Management Inc.304,786$4.24M0.1%N/A0.276%
4/22/2026 Pictet Asset Management Holding SA10,768$150K0.0%N/A0.010%
3/3/2026 Caitong International Asset Management Co. Ltd3,859$47K0.0%+954.4%0.004%
2/26/2026 Seven Fleet Capital Management LP11,571$140K0.1%N/A0.011%
2/19/2026 T. Rowe Price Investment Management Inc.4,517$55K0.0%-99.6%0.004%
2/19/2026 Invesco Ltd.175,914$2.13M0.0%-78.3%0.160%
2/18/2026 ADAR1 Capital Management LLC890,356$10.76M0.8%+2.8%0.811%
2/18/2026 XTX Topco Ltd189,673$2.29M0.1%N/A0.173%
2/18/2026 Voloridge Investment Management LLC153,363$1.85M0.0%N/A0.140%
2/18/2026 Virtus Investment Advisers LLC20,307$245K0.1%N/A0.018%
2/18/2026 Wellington Management Group LLP225,782$2.73M0.0%-4.4%0.206%
2/18/2026 SummitTX Capital L.P.218,399$2.64M0.1%+30.0%0.199%
2/18/2026 Tudor Investment Corp ET AL22,402$271K0.0%N/A0.020%
2/18/2026 Quadrature Capital Ltd15,465$187K0.0%-45.3%0.014%
2/18/2026 Numerai GP LLC112,648$1.36M0.2%+67.7%0.103%
2/18/2026 Perceptive Advisors LLC8,284,882$100.08M1.8%-7.5%7.544%
2/18/2026 Millennium Management LLC46,455$561K0.0%-88.9%0.042%
2/18/2026Janus Henderson Group PLC4,465,872$53.99M0.0%+76.1%4.067%
2/18/2026 Elmind Capital LP112,000$1.35M0.4%N/A0.102%
2/18/2026 Engineers Gate Manager LP18,358$222K0.0%N/A0.017%
2/18/2026 Commodore Capital LP5,650,000$68.25M4.5%+38.6%5.145%
2/18/2026 Cormorant Asset Management LP400,000$4.83M0.2%-20.0%0.364%
2/18/2026 Balyasny Asset Management L.P.858,684$10.37M0.0%-41.8%0.782%
2/18/2026 683 Capital Management LLC1,650,000$19.93M0.9%-6.3%1.502%
2/18/2026 ACT Capital Management LLC9,000$109K0.1%N/A0.008%
2/17/2026 Logos Global Management LP950,000$11.48M0.7%-34.5%0.865%
2/17/2026 ADAR1 Capital Management LLC890,356$10.76M0.8%+2.8%0.811%
2/17/2026 Schonfeld Strategic Advisors LLC21,052$254K0.0%-51.8%0.019%
2/17/2026 AQR Capital Management LLC27,847$336K0.0%-62.2%0.025%
2/17/2026 Trexquant Investment LP48,112$581K0.0%-78.4%0.044%
2/17/2026 Price T Rowe Associates Inc. MD107,548$1.30M0.0%+7.1%0.098%
2/17/2026 Adage Capital Partners GP L.L.C.2,777,055$33.55M0.1%-59.3%2.529%
2/17/2026 California State Teachers Retirement System79,090$955K0.0%+1,726.1%0.072%
2/17/2026 Russell Investments Group Ltd.65,438$790K0.0%+18.1%0.060%
2/17/2026 Atom Investors LP139,422$1.68M0.1%N/A0.127%
2/17/2026 State of Wisconsin Investment Board84,144$1.02M0.0%+506.4%0.077%
2/17/2026 Royal Bank of Canada15,643$188K0.0%-83.2%0.014%
2/17/2026 Persistent Asset Partners Ltd31,147$376K0.2%+35.9%0.028%
2/16/2026 Squarepoint Ops LLC76,562$925K0.0%N/A0.070%
2/16/2026 Sofinnova Investments Inc.527,099$6.37M0.3%N/A0.480%
2/16/2026 Verition Fund Management LLC29,487$356K0.0%-53.9%0.027%
2/16/2026 Mariner LLC46,342$560K0.0%-3.5%0.042%
2/16/2026 Landscape Capital Management L.L.C.12,226$148K0.0%+17.5%0.011%
2/16/2026 Barclays PLC295,177$3.57M0.0%-28.7%0.269%
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2/13/2026 Nantahala Capital Management LLC835,684$10.10M0.3%-10.7%0.761%
2/13/2026 The Manufacturers Life Insurance Company 26,988$326K0.0%+13.4%0.025%
2/13/2026 Alpha Wave Global LP317,678$3.84M0.5%-2.9%0.289%
2/13/2026 Rafferty Asset Management LLC17,673$213K0.0%N/A0.016%
2/13/2026 Headlands Technologies LLC30,543$369K0.0%N/A0.028%
2/13/2026 Charles Schwab Investment Management Inc.712,990$8.61M0.0%+10.5%0.649%
2/13/2026 Police & Firemen s Retirement System of New Jersey23,752$287K0.0%+23.3%0.022%
2/13/2026 State Street Corp2,069,884$25.00M0.0%+27.7%1.885%
2/13/2026 Caitong International Asset Management Co. Ltd4,454$54K0.1%+1,116.9%0.004%
2/13/2026 UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC98,838$1.19M0.0%N/A0.090%


AMLX Institutional Ownership - Frequently Asked Questions

During the previous two years, 180 institutional investors and hedge funds held shares of Amylyx Pharmaceuticals. The most heavily invested institutionals were BlackRock Inc. ($158.53M), Perceptive Advisors LLC ($100.08M), Jupiter Topco LLC ($94.01M), TCG Crossover Management LLC ($84.85M), Vanguard Group Inc. ($70.12M), Janus Henderson Group PLC ($69.26M), and Commodore Capital LP ($68.25M).Learn more on Amylyx Pharmaceuticals' institutional investors.

95.84% of Amylyx Pharmaceuticals' stock is owned by institutional investors. Learn more on AMLX's institutional investor holdings.

Of the 158 institutional investors that purchased Amylyx Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: BlackRock Inc. ($8.83M), Adage Capital Partners GP L.L.C. ($8.80M), Commodore Capital LP ($5.65M), Jupiter Topco LLC ($5.24M), First Light Asset Management LLC ($3.36M), Millennium Management LLC ($2.63M), and Janus Henderson Group PLC ($2.45M).

Institutional investors have bought a total of 49,801,157 shares in the last 24 months. This purchase volume represents approximately $754.90M in transactions.

Of the 51 institutional investors that sold Amylyx Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Adage Capital Partners GP L.L.C. ($4.04M), Nantahala Capital Management LLC ($2.10M), Millennium Management LLC ($1.47M), T. Rowe Price Investment Management Inc. ($1.19M), UBS Group AG ($861.15K), Perceptive Advisors LLC ($667.48K), and Invesco Ltd. ($634.73K).

Institutional investors have sold a total of 15,903,602 shares in the last 24 months. This volume of shares sold represents approximately $201.59M in transactions.



Institutional ownership data for NASDAQ:AMLX is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 8/27/2026. New 13F filings are added each quarter as they're published.
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