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Amylyx Pharmaceuticals (AMLX) Institutional Ownership

Amylyx Pharmaceuticals logo
$22.63 -0.72 (-3.10%)
As of 03:50 PM Eastern
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Institutional Ownership Changes (13F Filings) for Amylyx Pharmaceuticals (NASDAQ:AMLX)

Current
Institutional Ownership
Percentage
95.84%
Number of
Institutional Buyers
(last 12 months)
111
Total
Institutional Inflows
(last 12 months)
$584.73M
Number of
Institutional Sellers
(last 12 months)
53
Total
Institutional Outflows
(last 12 months)
$209.99M
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AMLX Institutional Buying and Selling by Quarter

Amylyx Pharmaceuticals Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
8/13/2026Connor Clark & Lunn Investment Management Ltd.721,002$12.95M0.0%N/A0.647%
8/10/2026 Great Lakes Advisors LLC12,807$230K0.0%N/A0.011%
8/7/2026 BlackRock Inc.8,827,085$158.53M0.0%N/A7.939%
8/7/2026 Deutsche Bank AG557,937$10.02M0.0%N/A0.502%
8/6/2026 Bank of New York Mellon Corp274,435$4.93M0.0%N/A0.247%
8/6/2026 State of Wyoming2,223$40K0.0%N/A0.002%
8/6/2026 GSA Capital Partners LLP39,241$705K0.0%N/A0.035%
6/4/2026Seven Fleet Capital Management LP16,671$232K0.1%+44.1%0.015%
5/19/2026Bank of America Corp DE1,330,689$18.50M0.0%-0.4%1.197%
5/19/2026Stempoint Capital LP669,685$9.31M1.8%+18.5%0.602%
5/19/2026Janus Henderson Group PLC4,986,073$69.26M0.0%+11.6%4.484%
5/18/2026ADAR1 Capital Management LLC1,000,604$13.91M0.8%+12.4%0.900%
5/18/2026 Amundi12,895$179K0.0%N/A0.012%
5/18/2026California State Teachers Retirement System65,002$904K0.0%-17.8%0.058%
5/18/2026Royal Bank of Canada12,383$172K0.0%-20.8%0.011%
5/16/2026The Manufacturers Life Insurance Company 38,781$539K0.0%+43.7%0.035%
5/16/2026First Light Asset Management LLC3,190,645$44.35M4.0%-4.9%2.870%
5/16/2026SummitTX Capital L.P.227,010$3.16M0.1%+3.9%0.204%
5/14/2026Siren L.L.C.1,230,000$17.10M0.5%N/A1.106%
5/14/2026Sei Investments Co.85,279$1.19M0.0%+61.3%0.077%
5/7/2026 Dimensional Fund Advisors LP903,192$12.54M0.0%+17.1%0.813%
5/7/2026 KBC Group NV1,863$26K0.0%N/A0.002%
5/7/2026 Swiss National Bank130,300$1.81M0.0%-19.4%0.117%
5/5/2026 Bank of New York Mellon Corp251,104$3.49M0.0%+15.5%0.226%
4/30/2026Hsbc Holdings PLC11,414$157K0.0%N/A0.010%
4/24/2026 iA Global Asset Management Inc.304,786$4.24M0.1%N/A0.276%
4/22/2026 Pictet Asset Management Holding SA10,768$150K0.0%N/A0.010%
3/3/2026 Caitong International Asset Management Co. Ltd3,859$47K0.0%+954.4%0.004%
2/26/2026Seven Fleet Capital Management LP11,571$140K0.1%N/A0.011%
2/19/2026T. Rowe Price Investment Management Inc.4,517$55K0.0%-99.6%0.004%
2/19/2026Invesco Ltd.175,914$2.13M0.0%-78.3%0.160%
2/18/2026ADAR1 Capital Management LLC890,356$10.76M0.8%+2.8%0.811%
2/18/2026XTX Topco Ltd189,673$2.29M0.1%N/A0.173%
2/18/2026Voloridge Investment Management LLC153,363$1.85M0.0%N/A0.140%
2/18/2026 Virtus Investment Advisers LLC20,307$245K0.1%N/A0.018%
2/18/2026Wellington Management Group LLP225,782$2.73M0.0%-4.4%0.206%
2/18/2026SummitTX Capital L.P.218,399$2.64M0.1%+30.0%0.199%
2/18/2026Tudor Investment Corp ET AL22,402$271K0.0%N/A0.020%
2/18/2026 Quadrature Capital Ltd15,465$187K0.0%-45.3%0.014%
2/18/2026Numerai GP LLC112,648$1.36M0.2%+67.7%0.103%
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2/18/2026Perceptive Advisors LLC8,284,882$100.08M1.8%-7.5%7.544%
2/18/2026Millennium Management LLC46,455$561K0.0%-88.9%0.042%
2/18/2026Janus Henderson Group PLC4,465,872$53.99M0.0%+76.1%4.067%
2/18/2026Elmind Capital LP112,000$1.35M0.4%N/A0.102%
2/18/2026Engineers Gate Manager LP18,358$222K0.0%N/A0.017%
2/18/2026Commodore Capital LP5,650,000$68.25M4.5%+38.6%5.145%
2/18/2026Cormorant Asset Management LP400,000$4.83M0.2%-20.0%0.364%
2/18/2026Balyasny Asset Management L.P.858,684$10.37M0.0%-41.8%0.782%
2/18/2026683 Capital Management LLC1,650,000$19.93M0.9%-6.3%1.502%
2/18/2026 ACT Capital Management LLC9,000$109K0.1%N/A0.008%
2/17/2026Logos Global Management LP950,000$11.48M0.7%-34.5%0.865%
2/17/2026ADAR1 Capital Management LLC890,356$10.76M0.8%+2.8%0.811%
2/17/2026Schonfeld Strategic Advisors LLC21,052$254K0.0%-51.8%0.019%
2/17/2026AQR Capital Management LLC27,847$336K0.0%-62.2%0.025%
2/17/2026Trexquant Investment LP48,112$581K0.0%-78.4%0.044%
2/17/2026Price T Rowe Associates Inc. MD107,548$1.30M0.0%+7.1%0.098%
2/17/2026Adage Capital Partners GP L.L.C.2,777,055$33.55M0.1%-59.3%2.529%
2/17/2026California State Teachers Retirement System79,090$955K0.0%+1,726.1%0.072%
2/17/2026 Russell Investments Group Ltd.65,438$790K0.0%+18.1%0.060%
2/17/2026Atom Investors LP139,422$1.68M0.1%N/A0.127%
2/17/2026State of Wisconsin Investment Board84,144$1.02M0.0%+506.4%0.077%
2/17/2026Royal Bank of Canada15,643$188K0.0%-83.2%0.014%
2/17/2026 Persistent Asset Partners Ltd31,147$376K0.2%+35.9%0.028%
2/16/2026Squarepoint Ops LLC76,562$925K0.0%N/A0.070%
2/16/2026Sofinnova Investments Inc.527,099$6.37M0.3%N/A0.480%
2/16/2026Verition Fund Management LLC29,487$356K0.0%-53.9%0.027%
2/16/2026Mariner LLC46,342$560K0.0%-3.5%0.042%
2/16/2026Landscape Capital Management L.L.C.12,226$148K0.0%+17.5%0.011%
2/16/2026Barclays PLC295,177$3.57M0.0%-28.7%0.269%
2/13/2026Nantahala Capital Management LLC835,684$10.10M0.3%-10.7%0.761%
2/13/2026The Manufacturers Life Insurance Company 26,988$326K0.0%+13.4%0.025%
2/13/2026Alpha Wave Global LP317,678$3.84M0.5%-2.9%0.289%
2/13/2026Rafferty Asset Management LLC17,673$213K0.0%N/A0.016%
2/13/2026Headlands Technologies LLC30,543$369K0.0%N/A0.028%
2/13/2026Charles Schwab Investment Management Inc.712,990$8.61M0.0%+10.5%0.649%
2/13/2026 Police & Firemen s Retirement System of New Jersey23,752$287K0.0%+23.3%0.022%
2/13/2026 State Street Corp2,069,884$25.00M0.0%+27.7%1.885%
2/13/2026 Caitong International Asset Management Co. Ltd4,454$54K0.1%+1,116.9%0.004%
2/13/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC98,838$1.19M0.0%N/A0.090%
2/13/2026Wells Fargo & Company MN146,309$1.77M0.0%+56.2%0.133%
2/12/2026MetLife Investment Management LLC49,654$600K0.0%+15.7%0.045%
2/12/2026Aldebaran Capital LLC198,508$2.40M2.2%-2.9%0.181%
2/12/2026Renaissance Technologies LLC192,500$2.33M0.0%+867.3%0.175%
2/12/2026 Dimensional Fund Advisors LP771,248$9.32M0.0%+51.3%0.702%
2/12/2026EntryPoint Capital LLC10,487$127K0.0%-38.9%0.010%
2/12/2026Integrated Quantitative Investments LLC27,234$329K0.1%N/A0.025%
2/12/2026Federated Hermes Inc.457,412$5.53M0.0%+115.4%0.417%
2/12/2026Informed Momentum Co LLC53,256$643K0.1%-29.1%0.048%
2/12/2026Patient Square Capital LP350,000$4.23M0.9%+10.7%0.319%
2/12/2026 Campbell & CO Investment Adviser LLC78,763$951K0.0%+221.7%0.072%
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2/12/2026Bank of Montreal Can138,525$1.67M0.0%-3.6%0.126%
2/12/2026 Alps Advisors Inc.90,172$1.09M0.0%N/A0.082%
2/12/2026 Swiss National Bank161,700$1.95M0.0%N/A0.147%
2/12/2026 Nuveen LLC283,948$3.43M0.0%+77.0%0.259%
2/11/2026 Meeder Asset Management Inc.2,099$25K0.0%N/A0.002%
2/11/2026 Deutsche Bank AG1,333,236$16.11M0.0%-2.4%1.214%
2/11/2026 Fox Run Management L.L.C.35,409$428K0.1%N/A0.032%
2/11/2026Franklin Resources Inc.1,200,096$14.50M0.0%N/A1.093%
2/10/2026Goldman Sachs Group Inc.2,613,221$31.57M0.0%+30.0%2.380%
2/10/2026 Jupiter Asset Management Ltd.15,574$188K0.0%N/A0.014%


AMLX Institutional Ownership - Frequently Asked Questions

During the previous two years, 177 institutional investors and hedge funds held shares of Amylyx Pharmaceuticals. The most heavily invested institutionals were BlackRock Inc. ($158.53M), Perceptive Advisors LLC ($100.08M), TCG Crossover Management LLC ($84.85M), Vanguard Group Inc. ($70.12M), Janus Henderson Group PLC ($69.26M), Commodore Capital LP ($68.25M), and First Light Asset Management LLC ($44.35M).Learn more on Amylyx Pharmaceuticals' institutional investors.

95.84% of Amylyx Pharmaceuticals' stock is owned by institutional investors. Learn more on AMLX's institutional investor holdings.

Of the 154 institutional investors that purchased Amylyx Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: BlackRock Inc. ($8.83M), Adage Capital Partners GP L.L.C. ($8.80M), Commodore Capital LP ($5.65M), First Light Asset Management LLC ($3.36M), AQR Capital Management LLC ($3.22M), Millennium Management LLC ($2.63M), and Janus Henderson Group PLC ($2.45M).

Institutional investors have bought a total of 42,585,046 shares in the last 24 months. This purchase volume represents approximately $584.73M in transactions.

Of the 52 institutional investors that sold Amylyx Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Adage Capital Partners GP L.L.C. ($4.04M), Nantahala Capital Management LLC ($2.10M), Millennium Management LLC ($1.47M), T. Rowe Price Investment Management Inc. ($1.19M), UBS Group AG ($861.15K), Qube Research & Technologies Ltd ($775.79K), and Perceptive Advisors LLC ($667.48K).

Institutional investors have sold a total of 17,276,571 shares in the last 24 months. This volume of shares sold represents approximately $209.99M in transactions.


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Institutional ownership data for NASDAQ:AMLX is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 8/13/2026. New 13F filings are added each quarter as they're published.
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