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Amylyx Pharmaceuticals (AMLX) Competitors

Amylyx Pharmaceuticals logo
$31.62 -0.47 (-1.46%)
Closing price 09/11/2026 04:00 PM Eastern
Extended Trading
$31.62 0.00 (0.00%)
As of 09/11/2026 07:51 PM Eastern
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AMLX vs. BBIO, EXEL, SMMT, BMRN, and HALO

Should you buy Amylyx Pharmaceuticals stock or one of its competitors? Amylyx Pharmaceuticals's main competitors and comparable companies include BridgeBio Pharma (BBIO), Exelixis (EXEL), Summit Therapeutics (SMMT), BioMarin Pharmaceutical (BMRN), and Halozyme Therapeutics (HALO). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Amylyx Pharmaceuticals compare to BridgeBio Pharma?

BridgeBio Pharma (NASDAQ:BBIO) and Amylyx Pharmaceuticals (NASDAQ:AMLX) are both healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their analyst recommendations, valuation, dividends, media sentiment, institutional ownership, profitability, earnings and risk.

Amylyx Pharmaceuticals has a net margin of 0.00% compared to BridgeBio Pharma's net margin of -97.03%. BridgeBio Pharma's return on equity of 0.00% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
BridgeBio Pharma-97.03% N/A -61.19%
Amylyx Pharmaceuticals N/A -52.92%-48.53%

BridgeBio Pharma has a beta of 0.97, indicating that its share price is 3% less volatile than the broader market. Comparatively, Amylyx Pharmaceuticals has a beta of -0.13, indicating that its share price is 113% less volatile than the broader market.

99.8% of BridgeBio Pharma shares are held by institutional investors. Comparatively, 95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. 14.2% of BridgeBio Pharma shares are held by company insiders. Comparatively, 10.9% of Amylyx Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

In the previous week, BridgeBio Pharma had 7 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 13 mentions for BridgeBio Pharma and 6 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 1.50 beat BridgeBio Pharma's score of 0.90 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
BridgeBio Pharma
6 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Amylyx Pharmaceuticals
4 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

BridgeBio Pharma currently has a consensus target price of $102.61, suggesting a potential upside of 41.65%. Amylyx Pharmaceuticals has a consensus target price of $36.50, suggesting a potential upside of 15.43%. Given BridgeBio Pharma's higher probable upside, equities research analysts plainly believe BridgeBio Pharma is more favorable than Amylyx Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BridgeBio Pharma
1 Sell rating(s)
2 Hold rating(s)
20 Buy rating(s)
0 Strong Buy rating(s)
2.83
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.00

Amylyx Pharmaceuticals has lower revenue, but higher earnings than BridgeBio Pharma. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than BridgeBio Pharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BridgeBio Pharma$713.07M19.86-$724.93M-$3.57N/A
Amylyx PharmaceuticalsN/AN/A-$144.74M-$1.43N/A

Summary

BridgeBio Pharma beats Amylyx Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

How does Amylyx Pharmaceuticals compare to Exelixis?

Amylyx Pharmaceuticals (NASDAQ:AMLX) and Exelixis (NASDAQ:EXEL) are both healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their risk, institutional ownership, dividends, analyst recommendations, valuation, media sentiment, profitability and earnings.

Amylyx Pharmaceuticals currently has a consensus price target of $36.50, suggesting a potential upside of 15.43%. Exelixis has a consensus price target of $50.07, suggesting a potential downside of 10.79%. Given Amylyx Pharmaceuticals' stronger consensus rating and higher possible upside, equities research analysts plainly believe Amylyx Pharmaceuticals is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.00
Exelixis
1 Sell rating(s)
12 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.38

In the previous week, Exelixis had 21 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 27 mentions for Exelixis and 6 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 1.50 beat Exelixis' score of 0.54 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amylyx Pharmaceuticals
4 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Exelixis
12 Very Positive mention(s)
3 Positive mention(s)
3 Neutral mention(s)
2 Negative mention(s)
6 Very Negative mention(s)
Positive

95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. Comparatively, 85.3% of Exelixis shares are held by institutional investors. 10.9% of Amylyx Pharmaceuticals shares are held by insiders. Comparatively, 2.6% of Exelixis shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Exelixis has higher revenue and earnings than Amylyx Pharmaceuticals. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than Exelixis, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amylyx PharmaceuticalsN/AN/A-$144.74M-$1.43N/A
Exelixis$2.44B5.71$782.57M$3.1817.65

Exelixis has a net margin of 35.33% compared to Amylyx Pharmaceuticals' net margin of 0.00%. Exelixis' return on equity of 42.17% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Amylyx PharmaceuticalsN/A -52.92% -48.53%
Exelixis 35.33%42.17%31.76%

Amylyx Pharmaceuticals has a beta of -0.13, suggesting that its share price is 113% less volatile than the broader market. Comparatively, Exelixis has a beta of 0.42, suggesting that its share price is 58% less volatile than the broader market.

Summary

Exelixis beats Amylyx Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

How does Amylyx Pharmaceuticals compare to Summit Therapeutics?

Amylyx Pharmaceuticals (NASDAQ:AMLX) and Summit Therapeutics (NASDAQ:SMMT) are both healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their institutional ownership, media sentiment, risk, valuation, analyst recommendations, dividends, earnings and profitability.

Amylyx Pharmaceuticals' return on equity of -52.92% beat Summit Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Amylyx PharmaceuticalsN/A -52.92% -48.53%
Summit Therapeutics N/A -168.94%-141.92%

Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than Summit Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amylyx PharmaceuticalsN/AN/A-$144.74M-$1.43N/A
Summit TherapeuticsN/AN/A-$1.08B-$1.12N/A

Amylyx Pharmaceuticals has a beta of -0.13, indicating that its share price is 113% less volatile than the broader market. Comparatively, Summit Therapeutics has a beta of -1.24, indicating that its share price is 224% less volatile than the broader market.

In the previous week, Summit Therapeutics had 3 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 9 mentions for Summit Therapeutics and 6 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 1.50 beat Summit Therapeutics' score of 1.19 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amylyx Pharmaceuticals
4 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Summit Therapeutics
6 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. Comparatively, 4.6% of Summit Therapeutics shares are held by institutional investors. 10.9% of Amylyx Pharmaceuticals shares are held by company insiders. Comparatively, 83.5% of Summit Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Amylyx Pharmaceuticals currently has a consensus price target of $36.50, indicating a potential upside of 15.43%. Summit Therapeutics has a consensus price target of $25.91, indicating a potential upside of 47.63%. Given Summit Therapeutics' higher probable upside, analysts clearly believe Summit Therapeutics is more favorable than Amylyx Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.00
Summit Therapeutics
1 Sell rating(s)
8 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.47

Summary

Amylyx Pharmaceuticals beats Summit Therapeutics on 9 of the 14 factors compared between the two stocks.

How does Amylyx Pharmaceuticals compare to BioMarin Pharmaceutical?

Amylyx Pharmaceuticals (NASDAQ:AMLX) and BioMarin Pharmaceutical (NASDAQ:BMRN) are both healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their analyst recommendations, dividends, earnings, profitability, institutional ownership, media sentiment, valuation and risk.

95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. Comparatively, 98.7% of BioMarin Pharmaceutical shares are held by institutional investors. 10.9% of Amylyx Pharmaceuticals shares are held by insiders. Comparatively, 0.7% of BioMarin Pharmaceutical shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

BioMarin Pharmaceutical has a net margin of 2.14% compared to Amylyx Pharmaceuticals' net margin of 0.00%. BioMarin Pharmaceutical's return on equity of 5.32% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Amylyx PharmaceuticalsN/A -52.92% -48.53%
BioMarin Pharmaceutical 2.14%5.32%3.69%

Amylyx Pharmaceuticals presently has a consensus target price of $36.50, suggesting a potential upside of 15.43%. BioMarin Pharmaceutical has a consensus target price of $89.17, suggesting a potential upside of 35.77%. Given BioMarin Pharmaceutical's higher possible upside, analysts clearly believe BioMarin Pharmaceutical is more favorable than Amylyx Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.00
BioMarin Pharmaceutical
1 Sell rating(s)
6 Hold rating(s)
14 Buy rating(s)
2 Strong Buy rating(s)
2.74

BioMarin Pharmaceutical has higher revenue and earnings than Amylyx Pharmaceuticals. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than BioMarin Pharmaceutical, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amylyx PharmaceuticalsN/AN/A-$144.74M-$1.43N/A
BioMarin Pharmaceutical$3.22B3.95$348.90M$0.37177.51

In the previous week, BioMarin Pharmaceutical had 15 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 21 mentions for BioMarin Pharmaceutical and 6 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 1.50 beat BioMarin Pharmaceutical's score of 0.79 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amylyx Pharmaceuticals
4 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
BioMarin Pharmaceutical
8 Very Positive mention(s)
4 Positive mention(s)
6 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Amylyx Pharmaceuticals has a beta of -0.13, suggesting that its share price is 113% less volatile than the broader market. Comparatively, BioMarin Pharmaceutical has a beta of 0.24, suggesting that its share price is 76% less volatile than the broader market.

Summary

BioMarin Pharmaceutical beats Amylyx Pharmaceuticals on 12 of the 15 factors compared between the two stocks.

How does Amylyx Pharmaceuticals compare to Halozyme Therapeutics?

Halozyme Therapeutics (NASDAQ:HALO) and Amylyx Pharmaceuticals (NASDAQ:AMLX) are both healthcare companies, but which is the better stock? We will contrast the two companies based on the strength of their institutional ownership, analyst recommendations, media sentiment, earnings, dividends, profitability, valuation and risk.

Halozyme Therapeutics presently has a consensus price target of $91.20, indicating a potential downside of 14.93%. Amylyx Pharmaceuticals has a consensus price target of $36.50, indicating a potential upside of 15.43%. Given Amylyx Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Amylyx Pharmaceuticals is more favorable than Halozyme Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Halozyme Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.00

97.8% of Halozyme Therapeutics shares are held by institutional investors. Comparatively, 95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. 2.5% of Halozyme Therapeutics shares are held by insiders. Comparatively, 10.9% of Amylyx Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Halozyme Therapeutics has higher revenue and earnings than Amylyx Pharmaceuticals. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than Halozyme Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Halozyme Therapeutics$1.40B8.71$316.89M$3.3532.00
Amylyx PharmaceuticalsN/AN/A-$144.74M-$1.43N/A

Halozyme Therapeutics has a net margin of 24.86% compared to Amylyx Pharmaceuticals' net margin of 0.00%. Halozyme Therapeutics' return on equity of 260.98% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Halozyme Therapeutics24.86% 260.98% 23.91%
Amylyx Pharmaceuticals N/A -52.92%-48.53%

In the previous week, Halozyme Therapeutics had 7 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 13 mentions for Halozyme Therapeutics and 6 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 1.50 beat Halozyme Therapeutics' score of 1.02 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Halozyme Therapeutics
9 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Amylyx Pharmaceuticals
4 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Halozyme Therapeutics has a beta of 0.88, meaning that its stock price is 12% less volatile than the broader market. Comparatively, Amylyx Pharmaceuticals has a beta of -0.13, meaning that its stock price is 113% less volatile than the broader market.

Summary

Halozyme Therapeutics beats Amylyx Pharmaceuticals on 11 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding AMLX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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AMLX vs. The Competition

MetricAmylyx PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$3.52B$3.84B$7.13B$12.72B
Dividend YieldN/A3.63%2.56%11.15%
P/E Ratio-22.1114.25275.2425.29
Price / SalesN/A1,473.06655.9998.94
Price / CashN/A106.6877.0451.44
Price / Book11.3715.1210.336.20
Net Income-$144.74M-$22.86M$3.50B$358.50M
7 Day Performance-7.27%-4.34%-3.32%-2.35%
1 Month Performance35.42%-0.02%-0.41%-2.77%
1 Year Performance171.42%40.64%19.21%7.63%

Amylyx Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
AMLX
Amylyx Pharmaceuticals
3.949 of 5 stars
$31.62
-1.5%
$36.50
+15.4%
+167.1%$3.52BN/AN/A136
BBIO
BridgeBio Pharma
3.4571 of 5 stars
$74.84
flat
$101.53
+35.7%
+37.7%$14.63B$502.08MN/A400
EXEL
Exelixis
2.4691 of 5 stars
$59.01
flat
$50.07
-15.2%
+43.6%$14.62B$2.32B18.561,077
SMMT
Summit Therapeutics
3.6754 of 5 stars
$17.60
flat
$24.07
+36.8%
-5.6%$14.04BN/AN/A110
BMRN
BioMarin Pharmaceutical
4.6227 of 5 stars
$66.53
flat
$89.17
+34.0%
+17.5%$12.88B$3.22B179.813,221

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This page (NASDAQ:AMLX) was last updated on 9/12/2026 by MarketBeat.com Staff.
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