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Amylyx Pharmaceuticals (AMLX) Competitors

Amylyx Pharmaceuticals logo
$20.31 -0.44 (-2.12%)
Closing price 07/31/2026 04:00 PM Eastern
Extended Trading
$19.75 -0.56 (-2.76%)
As of 07/31/2026 07:34 PM Eastern
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AMLX vs. IMVT, PCVX, IBRX, RYTM, and MIRM

Should you buy Amylyx Pharmaceuticals stock or one of its competitors? MarketBeat compares Amylyx Pharmaceuticals with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Amylyx Pharmaceuticals include Immunovant (IMVT), Vaxcyte (PCVX), ImmunityBio (IBRX), Rhythm Pharmaceuticals (RYTM), and Mirum Pharmaceuticals (MIRM).

How does Amylyx Pharmaceuticals compare to Immunovant?

Amylyx Pharmaceuticals (NASDAQ:AMLX) and Immunovant (NASDAQ:IMVT) are both mid-cap healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their institutional ownership, dividends, risk, valuation, analyst recommendations, profitability, media sentiment and earnings.

In the previous week, Amylyx Pharmaceuticals had 1 more articles in the media than Immunovant. MarketBeat recorded 6 mentions for Amylyx Pharmaceuticals and 5 mentions for Immunovant. Amylyx Pharmaceuticals' average media sentiment score of 1.09 beat Immunovant's score of 1.05 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amylyx Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Immunovant
3 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Amylyx Pharmaceuticals currently has a consensus price target of $24.63, indicating a potential upside of 21.25%. Immunovant has a consensus price target of $42.11, indicating a potential upside of 9.04%. Given Amylyx Pharmaceuticals' stronger consensus rating and higher possible upside, equities research analysts clearly believe Amylyx Pharmaceuticals is more favorable than Immunovant.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.90
Immunovant
1 Sell rating(s)
3 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.50

95.8% of Amylyx Pharmaceuticals shares are owned by institutional investors. Comparatively, 47.1% of Immunovant shares are owned by institutional investors. 10.9% of Amylyx Pharmaceuticals shares are owned by company insiders. Comparatively, 1.9% of Immunovant shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Amylyx Pharmaceuticals has higher revenue and earnings than Immunovant. Immunovant is trading at a lower price-to-earnings ratio than Amylyx Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amylyx Pharmaceuticals$87.37M25.85-$144.74M-$1.50N/A
ImmunovantN/AN/A-$505.61M-$2.78N/A

Amylyx Pharmaceuticals' return on equity of -55.69% beat Immunovant's return on equity.

Company Net Margins Return on Equity Return on Assets
Amylyx PharmaceuticalsN/A -55.69% -50.73%
Immunovant N/A -65.66%-59.88%

Amylyx Pharmaceuticals has a beta of -0.21, indicating that its share price is 121% less volatile than the broader market. Comparatively, Immunovant has a beta of 0.77, indicating that its share price is 23% less volatile than the broader market.

Summary

Amylyx Pharmaceuticals beats Immunovant on 14 of the 15 factors compared between the two stocks.

How does Amylyx Pharmaceuticals compare to Vaxcyte?

Amylyx Pharmaceuticals (NASDAQ:AMLX) and Vaxcyte (NASDAQ:PCVX) are both mid-cap healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their risk, valuation, profitability, media sentiment, analyst recommendations, earnings, institutional ownership and dividends.

Amylyx Pharmaceuticals has a beta of -0.21, meaning that its stock price is 121% less volatile than the broader market. Comparatively, Vaxcyte has a beta of 1.23, meaning that its stock price is 23% more volatile than the broader market.

Amylyx Pharmaceuticals currently has a consensus target price of $24.63, suggesting a potential upside of 21.25%. Vaxcyte has a consensus target price of $86.00, suggesting a potential upside of 59.02%. Given Vaxcyte's higher possible upside, analysts clearly believe Vaxcyte is more favorable than Amylyx Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.90
Vaxcyte
2 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.44

Vaxcyte's return on equity of -32.51% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Amylyx PharmaceuticalsN/A -55.69% -50.73%
Vaxcyte N/A -32.51%-29.51%

95.8% of Amylyx Pharmaceuticals shares are owned by institutional investors. Comparatively, 96.8% of Vaxcyte shares are owned by institutional investors. 10.9% of Amylyx Pharmaceuticals shares are owned by company insiders. Comparatively, 3.3% of Vaxcyte shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

In the previous week, Vaxcyte had 13 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 19 mentions for Vaxcyte and 6 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 1.09 beat Vaxcyte's score of 0.95 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amylyx Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Vaxcyte
13 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Amylyx Pharmaceuticals has higher revenue and earnings than Vaxcyte. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than Vaxcyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amylyx Pharmaceuticals$87.37M25.85-$144.74M-$1.50N/A
VaxcyteN/AN/A-$766.63M-$6.88N/A

Summary

Amylyx Pharmaceuticals beats Vaxcyte on 8 of the 15 factors compared between the two stocks.

How does Amylyx Pharmaceuticals compare to ImmunityBio?

Amylyx Pharmaceuticals (NASDAQ:AMLX) and ImmunityBio (NASDAQ:IBRX) are both mid-cap healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their analyst recommendations, risk, earnings, profitability, institutional ownership, media sentiment, valuation and dividends.

Amylyx Pharmaceuticals currently has a consensus target price of $24.63, indicating a potential upside of 21.25%. ImmunityBio has a consensus target price of $14.20, indicating a potential upside of 98.05%. Given ImmunityBio's higher possible upside, analysts clearly believe ImmunityBio is more favorable than Amylyx Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.90
ImmunityBio
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.71

Amylyx Pharmaceuticals has a beta of -0.21, indicating that its share price is 121% less volatile than the broader market. Comparatively, ImmunityBio has a beta of 0.03, indicating that its share price is 97% less volatile than the broader market.

Amylyx Pharmaceuticals has higher earnings, but lower revenue than ImmunityBio. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than ImmunityBio, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amylyx Pharmaceuticals$87.37M25.85-$144.74M-$1.50N/A
ImmunityBio$113.29M66.29-$351.40M-$0.85N/A

Amylyx Pharmaceuticals has a net margin of 0.00% compared to ImmunityBio's net margin of -606.15%. ImmunityBio's return on equity of 0.00% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Amylyx PharmaceuticalsN/A -55.69% -50.73%
ImmunityBio -606.15%N/A -59.53%

In the previous week, ImmunityBio had 6 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 12 mentions for ImmunityBio and 6 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 1.09 beat ImmunityBio's score of 0.56 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amylyx Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
ImmunityBio
5 Very Positive mention(s)
2 Positive mention(s)
4 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

95.8% of Amylyx Pharmaceuticals shares are owned by institutional investors. Comparatively, 8.6% of ImmunityBio shares are owned by institutional investors. 10.9% of Amylyx Pharmaceuticals shares are owned by company insiders. Comparatively, 66.1% of ImmunityBio shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Summary

ImmunityBio beats Amylyx Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Amylyx Pharmaceuticals compare to Rhythm Pharmaceuticals?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and Amylyx Pharmaceuticals (NASDAQ:AMLX) are both mid-cap healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their institutional ownership, profitability, earnings, valuation, risk, media sentiment, dividends and analyst recommendations.

Amylyx Pharmaceuticals has a net margin of 0.00% compared to Rhythm Pharmaceuticals' net margin of -93.33%. Amylyx Pharmaceuticals' return on equity of -55.69% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-93.33% -203.25% -44.99%
Amylyx Pharmaceuticals N/A -55.69%-50.73%

95.8% of Amylyx Pharmaceuticals shares are owned by institutional investors. 5.9% of Rhythm Pharmaceuticals shares are owned by insiders. Comparatively, 10.9% of Amylyx Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

In the previous week, Rhythm Pharmaceuticals had 10 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 16 mentions for Rhythm Pharmaceuticals and 6 mentions for Amylyx Pharmaceuticals. Rhythm Pharmaceuticals' average media sentiment score of 1.18 beat Amylyx Pharmaceuticals' score of 1.09 indicating that Rhythm Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rhythm Pharmaceuticals
10 Very Positive mention(s)
2 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Amylyx Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Rhythm Pharmaceuticals presently has a consensus price target of $138.73, indicating a potential upside of 39.78%. Amylyx Pharmaceuticals has a consensus price target of $24.63, indicating a potential upside of 21.25%. Given Rhythm Pharmaceuticals' higher probable upside, research analysts clearly believe Rhythm Pharmaceuticals is more favorable than Amylyx Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
15 Buy rating(s)
0 Strong Buy rating(s)
2.78
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.90

Amylyx Pharmaceuticals has lower revenue, but higher earnings than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Amylyx Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$189.76M35.84-$196.54M-$3.13N/A
Amylyx Pharmaceuticals$87.37M25.85-$144.74M-$1.50N/A

Rhythm Pharmaceuticals has a beta of 1.92, suggesting that its stock price is 92% more volatile than the broader market. Comparatively, Amylyx Pharmaceuticals has a beta of -0.21, suggesting that its stock price is 121% less volatile than the broader market.

Summary

Amylyx Pharmaceuticals beats Rhythm Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Amylyx Pharmaceuticals compare to Mirum Pharmaceuticals?

Mirum Pharmaceuticals (NASDAQ:MIRM) and Amylyx Pharmaceuticals (NASDAQ:AMLX) are both mid-cap healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their dividends, institutional ownership, media sentiment, earnings, analyst recommendations, risk, profitability and valuation.

Amylyx Pharmaceuticals has a net margin of 0.00% compared to Mirum Pharmaceuticals' net margin of -140.24%. Mirum Pharmaceuticals' return on equity of -11.28% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Mirum Pharmaceuticals-140.24% -11.28% -3.84%
Amylyx Pharmaceuticals N/A -55.69%-50.73%

In the previous week, Mirum Pharmaceuticals had 5 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 11 mentions for Mirum Pharmaceuticals and 6 mentions for Amylyx Pharmaceuticals. Mirum Pharmaceuticals' average media sentiment score of 1.37 beat Amylyx Pharmaceuticals' score of 1.09 indicating that Mirum Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Mirum Pharmaceuticals
7 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Amylyx Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Mirum Pharmaceuticals has a beta of 0.52, meaning that its share price is 48% less volatile than the broader market. Comparatively, Amylyx Pharmaceuticals has a beta of -0.21, meaning that its share price is 121% less volatile than the broader market.

Mirum Pharmaceuticals currently has a consensus target price of $143.40, indicating a potential upside of 35.35%. Amylyx Pharmaceuticals has a consensus target price of $24.63, indicating a potential upside of 21.25%. Given Mirum Pharmaceuticals' stronger consensus rating and higher possible upside, equities research analysts plainly believe Mirum Pharmaceuticals is more favorable than Amylyx Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mirum Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.93
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.90

95.8% of Amylyx Pharmaceuticals shares are owned by institutional investors. 8.3% of Mirum Pharmaceuticals shares are owned by insiders. Comparatively, 10.9% of Amylyx Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Mirum Pharmaceuticals has higher revenue and earnings than Amylyx Pharmaceuticals. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than Mirum Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Mirum Pharmaceuticals$521.31M12.39-$23.36M-$13.61N/A
Amylyx Pharmaceuticals$87.37M25.85-$144.74M-$1.50N/A

Summary

Mirum Pharmaceuticals beats Amylyx Pharmaceuticals on 11 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding AMLX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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AMLX vs. The Competition

MetricAmylyx PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$2.26B$3.55B$7.17B$12.47B
Dividend YieldN/A3.79%2.60%10.03%
P/E Ratio-13.544.31222.5322.11
Price / Sales25.851,250.60584.7090.03
Price / CashN/A44.8028.6046.71
Price / Book7.3116.7810.936.07
Net Income-$144.74M-$12.56M$3.50B$348.34M
7 Day Performance10.32%-1.47%-0.24%0.09%
1 Month Performance11.17%-8.45%-3.70%-5.17%
1 Year Performance163.08%48.32%61.98%18.61%

Amylyx Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
AMLX
Amylyx Pharmaceuticals
3.6394 of 5 stars
$20.31
-2.1%
$24.63
+21.2%
+163.1%$2.26B$87.37MN/A200
IMVT
Immunovant
1.8784 of 5 stars
$40.09
+1.7%
$42.11
+5.0%
+145.8%$8.13BN/AN/A120
PCVX
Vaxcyte
2.7511 of 5 stars
$55.50
+1.5%
$86.00
+55.0%
+63.8%$7.89BN/AN/A160
IBRX
ImmunityBio
2.5394 of 5 stars
$6.99
-1.5%
$14.20
+103.1%
+202.5%$7.44B$113.29MN/A590
RYTM
Rhythm Pharmaceuticals
3.3904 of 5 stars
$106.13
+3.9%
$138.73
+30.7%
+12.4%$7.00B$189.76MN/A140

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This page (NASDAQ:AMLX) was last updated on 8/2/2026 by MarketBeat.com Staff.
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