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Amylyx Pharmaceuticals (AMLX) Competitors

Amylyx Pharmaceuticals logo
$17.41 -0.36 (-2.03%)
Closing price 04:00 PM Eastern
Extended Trading
$17.40 -0.01 (-0.06%)
As of 06:18 PM Eastern
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AMLX vs. IMVT, RYTM, MIRM, SYRE, and LNTH

Should you buy Amylyx Pharmaceuticals stock or one of its competitors? MarketBeat compares Amylyx Pharmaceuticals with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Amylyx Pharmaceuticals include Immunovant (IMVT), Rhythm Pharmaceuticals (RYTM), Mirum Pharmaceuticals (MIRM), Spyre Therapeutics (SYRE), and Lantheus (LNTH). These companies are all part of the "pharmaceutical products" industry.

How does Amylyx Pharmaceuticals compare to Immunovant?

Immunovant (NASDAQ:IMVT) and Amylyx Pharmaceuticals (NASDAQ:AMLX) are both medical companies, but which is the superior investment? We will contrast the two companies based on the strength of their dividends, media sentiment, valuation, analyst recommendations, risk, institutional ownership, profitability and earnings.

In the previous week, Immunovant had 10 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 13 mentions for Immunovant and 3 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 1.87 beat Immunovant's score of 0.46 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Immunovant
5 Very Positive mention(s)
3 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Amylyx Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

47.1% of Immunovant shares are owned by institutional investors. Comparatively, 95.8% of Amylyx Pharmaceuticals shares are owned by institutional investors. 1.8% of Immunovant shares are owned by insiders. Comparatively, 10.9% of Amylyx Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Immunovant presently has a consensus target price of $39.70, indicating a potential upside of 2.58%. Amylyx Pharmaceuticals has a consensus target price of $24.25, indicating a potential upside of 39.29%. Given Amylyx Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Amylyx Pharmaceuticals is more favorable than Immunovant.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Immunovant
1 Sell rating(s)
4 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.45
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.90

Amylyx Pharmaceuticals' return on equity of -55.69% beat Immunovant's return on equity.

Company Net Margins Return on Equity Return on Assets
ImmunovantN/A -65.66% -59.88%
Amylyx Pharmaceuticals N/A -55.69%-50.73%

Immunovant is trading at a lower price-to-earnings ratio than Amylyx Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ImmunovantN/AN/A-$505.61M-$2.78N/A
Amylyx PharmaceuticalsN/AN/A-$144.74M-$1.50N/A

Immunovant has a beta of 0.76, meaning that its stock price is 24% less volatile than the broader market. Comparatively, Amylyx Pharmaceuticals has a beta of -0.2, meaning that its stock price is 120% less volatile than the broader market.

Summary

Amylyx Pharmaceuticals beats Immunovant on 12 of the 14 factors compared between the two stocks.

How does Amylyx Pharmaceuticals compare to Rhythm Pharmaceuticals?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and Amylyx Pharmaceuticals (NASDAQ:AMLX) are both medical companies, but which is the better investment? We will compare the two businesses based on the strength of their dividends, risk, valuation, media sentiment, analyst recommendations, earnings, institutional ownership and profitability.

95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. 5.9% of Rhythm Pharmaceuticals shares are held by company insiders. Comparatively, 10.9% of Amylyx Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Amylyx Pharmaceuticals has a net margin of 0.00% compared to Rhythm Pharmaceuticals' net margin of -93.33%. Amylyx Pharmaceuticals' return on equity of -55.69% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-93.33% -203.25% -44.99%
Amylyx Pharmaceuticals N/A -55.69%-50.73%

Amylyx Pharmaceuticals has lower revenue, but higher earnings than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Amylyx Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$189.76M38.82-$196.54M-$3.13N/A
Amylyx PharmaceuticalsN/AN/A-$144.74M-$1.50N/A

Rhythm Pharmaceuticals currently has a consensus target price of $138.29, indicating a potential upside of 28.65%. Amylyx Pharmaceuticals has a consensus target price of $24.25, indicating a potential upside of 39.29%. Given Amylyx Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Amylyx Pharmaceuticals is more favorable than Rhythm Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
14 Buy rating(s)
0 Strong Buy rating(s)
2.76
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.90

Rhythm Pharmaceuticals has a beta of 1.88, indicating that its share price is 88% more volatile than the broader market. Comparatively, Amylyx Pharmaceuticals has a beta of -0.2, indicating that its share price is 120% less volatile than the broader market.

In the previous week, Rhythm Pharmaceuticals and Rhythm Pharmaceuticals both had 3 articles in the media. Amylyx Pharmaceuticals' average media sentiment score of 1.87 beat Rhythm Pharmaceuticals' score of 1.14 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rhythm Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Amylyx Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Summary

Amylyx Pharmaceuticals beats Rhythm Pharmaceuticals on 11 of the 15 factors compared between the two stocks.

How does Amylyx Pharmaceuticals compare to Mirum Pharmaceuticals?

Mirum Pharmaceuticals (NASDAQ:MIRM) and Amylyx Pharmaceuticals (NASDAQ:AMLX) are both medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their risk, analyst recommendations, earnings, valuation, institutional ownership, dividends, media sentiment and profitability.

Amylyx Pharmaceuticals has a net margin of 0.00% compared to Mirum Pharmaceuticals' net margin of -140.24%. Mirum Pharmaceuticals' return on equity of -11.28% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Mirum Pharmaceuticals-140.24% -11.28% -3.84%
Amylyx Pharmaceuticals N/A -55.69%-50.73%

Mirum Pharmaceuticals has a beta of 0.48, indicating that its share price is 52% less volatile than the broader market. Comparatively, Amylyx Pharmaceuticals has a beta of -0.2, indicating that its share price is 120% less volatile than the broader market.

95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. 8.3% of Mirum Pharmaceuticals shares are held by insiders. Comparatively, 10.9% of Amylyx Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Mirum Pharmaceuticals has higher revenue and earnings than Amylyx Pharmaceuticals. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than Mirum Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Mirum Pharmaceuticals$569.61M12.74-$23.36M-$13.61N/A
Amylyx PharmaceuticalsN/AN/A-$144.74M-$1.50N/A

In the previous week, Mirum Pharmaceuticals had 7 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 10 mentions for Mirum Pharmaceuticals and 3 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 1.87 beat Mirum Pharmaceuticals' score of 0.78 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Mirum Pharmaceuticals
6 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Amylyx Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Mirum Pharmaceuticals presently has a consensus price target of $143.40, indicating a potential upside of 20.46%. Amylyx Pharmaceuticals has a consensus price target of $24.25, indicating a potential upside of 39.29%. Given Amylyx Pharmaceuticals' higher possible upside, analysts clearly believe Amylyx Pharmaceuticals is more favorable than Mirum Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mirum Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.93
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.90

Summary

Mirum Pharmaceuticals beats Amylyx Pharmaceuticals on 9 of the 15 factors compared between the two stocks.

How does Amylyx Pharmaceuticals compare to Spyre Therapeutics?

Spyre Therapeutics (NASDAQ:SYRE) and Amylyx Pharmaceuticals (NASDAQ:AMLX) are both medical companies, but which is the better business? We will contrast the two companies based on the strength of their media sentiment, institutional ownership, valuation, profitability, analyst recommendations, risk, dividends and earnings.

80.4% of Spyre Therapeutics shares are owned by institutional investors. Comparatively, 95.8% of Amylyx Pharmaceuticals shares are owned by institutional investors. 15.7% of Spyre Therapeutics shares are owned by company insiders. Comparatively, 10.9% of Amylyx Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

In the previous week, Spyre Therapeutics had 2 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 5 mentions for Spyre Therapeutics and 3 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 1.87 beat Spyre Therapeutics' score of 1.03 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Spyre Therapeutics
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Amylyx Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Spyre Therapeutics currently has a consensus price target of $101.42, indicating a potential upside of 8.20%. Amylyx Pharmaceuticals has a consensus price target of $24.25, indicating a potential upside of 39.29%. Given Amylyx Pharmaceuticals' higher probable upside, analysts plainly believe Amylyx Pharmaceuticals is more favorable than Spyre Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Spyre Therapeutics
1 Sell rating(s)
0 Hold rating(s)
11 Buy rating(s)
1 Strong Buy rating(s)
2.92
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.90

Spyre Therapeutics has a beta of 3.02, suggesting that its stock price is 202% more volatile than the broader market. Comparatively, Amylyx Pharmaceuticals has a beta of -0.2, suggesting that its stock price is 120% less volatile than the broader market.

Amylyx Pharmaceuticals has lower revenue, but higher earnings than Spyre Therapeutics. Spyre Therapeutics is trading at a lower price-to-earnings ratio than Amylyx Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Spyre Therapeutics$890K9,261.37-$155.20M-$2.08N/A
Amylyx PharmaceuticalsN/AN/A-$144.74M-$1.50N/A

Spyre Therapeutics' return on equity of -42.88% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Spyre TherapeuticsN/A -42.88% -27.76%
Amylyx Pharmaceuticals N/A -55.69%-50.73%

Summary

Spyre Therapeutics beats Amylyx Pharmaceuticals on 8 of the 14 factors compared between the two stocks.

How does Amylyx Pharmaceuticals compare to Lantheus?

Amylyx Pharmaceuticals (NASDAQ:AMLX) and Lantheus (NASDAQ:LNTH) are both medical companies, but which is the better business? We will compare the two companies based on the strength of their earnings, institutional ownership, risk, dividends, valuation, profitability, media sentiment and analyst recommendations.

In the previous week, Lantheus had 1 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 4 mentions for Lantheus and 3 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 1.87 beat Lantheus' score of 1.19 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amylyx Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Lantheus
1 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Lantheus has higher revenue and earnings than Amylyx Pharmaceuticals. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than Lantheus, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amylyx PharmaceuticalsN/AN/A-$144.74M-$1.50N/A
Lantheus$1.54B4.45$233.56M$4.1525.40

Amylyx Pharmaceuticals has a beta of -0.2, indicating that its stock price is 120% less volatile than the broader market. Comparatively, Lantheus has a beta of -0.06, indicating that its stock price is 106% less volatile than the broader market.

Lantheus has a net margin of 18.05% compared to Amylyx Pharmaceuticals' net margin of 0.00%. Lantheus' return on equity of 29.32% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Amylyx PharmaceuticalsN/A -55.69% -50.73%
Lantheus 18.05%29.32%15.00%

Amylyx Pharmaceuticals presently has a consensus price target of $24.25, suggesting a potential upside of 39.29%. Lantheus has a consensus price target of $108.29, suggesting a potential upside of 2.75%. Given Amylyx Pharmaceuticals' stronger consensus rating and higher probable upside, equities analysts clearly believe Amylyx Pharmaceuticals is more favorable than Lantheus.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.90
Lantheus
0 Sell rating(s)
3 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.73

95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. Comparatively, 99.1% of Lantheus shares are held by institutional investors. 10.9% of Amylyx Pharmaceuticals shares are held by insiders. Comparatively, 1.7% of Lantheus shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Summary

Lantheus beats Amylyx Pharmaceuticals on 10 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding AMLX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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AMLX vs. The Competition

MetricAmylyx PharmaceuticalsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$1.94B$2.99B$6.83B$12.42B
Dividend YieldN/A2.05%2.68%8.01%
P/E Ratio-11.6119.1727.1524.29
Price / SalesN/A499.40524.3395.60
Price / CashN/A56.8029.2249.39
Price / Book6.264.2210.756.29
Net Income-$144.74M$64.26M$3.58B$330.86M
7 Day Performance-3.12%-3.22%-2.10%-2.41%
1 Month Performance19.33%2.12%3.32%-0.64%
1 Year Performance126.69%22.04%28.17%20.09%

Amylyx Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
AMLX
Amylyx Pharmaceuticals
3.1371 of 5 stars
$17.41
-2.0%
$24.25
+39.3%
+131.4%$1.94BN/AN/A200
IMVT
Immunovant
2.1401 of 5 stars
$38.60
-0.5%
$39.70
+2.8%
+119.0%$7.96BN/AN/A120
RYTM
Rhythm Pharmaceuticals
3.2754 of 5 stars
$111.68
-2.2%
$136.13
+21.9%
+25.0%$7.82B$189.76MN/A140
MIRM
Mirum Pharmaceuticals
2.5109 of 5 stars
$121.91
-2.9%
$143.00
+17.3%
+131.9%$7.66B$521.31MN/A140
SYRE
Spyre Therapeutics
1.8361 of 5 stars
$88.74
+2.4%
$95.83
+8.0%
+522.9%$7.62B$890KN/A73

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This page (NASDAQ:AMLX) was last updated on 7/13/2026 by MarketBeat.com Staff.
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