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Protagonist Therapeutics (PTGX) Competitors

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$140.29 +1.10 (+0.79%)
As of 12:24 PM Eastern
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PTGX vs. BIIB, ALNY, INSM, ROIV, and INCY

Should you buy Protagonist Therapeutics stock or one of its competitors? Protagonist Therapeutics's main competitors and comparable companies include Biogen (BIIB), Alnylam Pharmaceuticals (ALNY), Insmed (INSM), Roivant Sciences (ROIV), and Incyte (INCY). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Protagonist Therapeutics compare to Biogen?

Biogen (NASDAQ:BIIB) and Protagonist Therapeutics (NASDAQ:PTGX) are both healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their profitability, valuation, risk, institutional ownership, media sentiment, earnings, analyst recommendations and dividends.

87.9% of Biogen shares are held by institutional investors. Comparatively, 98.6% of Protagonist Therapeutics shares are held by institutional investors. 0.3% of Biogen shares are held by company insiders. Comparatively, 5.2% of Protagonist Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

In the previous week, Biogen had 6 more articles in the media than Protagonist Therapeutics. MarketBeat recorded 8 mentions for Biogen and 2 mentions for Protagonist Therapeutics. Biogen's average media sentiment score of 1.02 beat Protagonist Therapeutics' score of 0.83 indicating that Biogen is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Biogen
4 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Protagonist Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Biogen has higher revenue and earnings than Protagonist Therapeutics. Biogen is trading at a lower price-to-earnings ratio than Protagonist Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Biogen$9.89B3.30$1.29B$5.6539.15
Protagonist Therapeutics$46.02M196.84-$130.15M$1.03135.91

Protagonist Therapeutics has a net margin of 29.40% compared to Biogen's net margin of 8.32%. Protagonist Therapeutics' return on equity of 12.03% beat Biogen's return on equity.

Company Net Margins Return on Equity Return on Assets
Biogen8.32% 11.18% 6.88%
Protagonist Therapeutics 29.40%12.03%11.23%

Biogen presently has a consensus target price of $230.14, suggesting a potential upside of 4.03%. Protagonist Therapeutics has a consensus target price of $147.13, suggesting a potential upside of 5.10%. Given Protagonist Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Protagonist Therapeutics is more favorable than Biogen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Biogen
1 Sell rating(s)
13 Hold rating(s)
17 Buy rating(s)
1 Strong Buy rating(s)
2.56
Protagonist Therapeutics
0 Sell rating(s)
2 Hold rating(s)
16 Buy rating(s)
0 Strong Buy rating(s)
2.89

Biogen has a beta of 0.09, suggesting that its stock price is 91% less volatile than the broader market. Comparatively, Protagonist Therapeutics has a beta of 1.53, suggesting that its stock price is 53% more volatile than the broader market.

Summary

Protagonist Therapeutics beats Biogen on 10 of the 17 factors compared between the two stocks.

How does Protagonist Therapeutics compare to Alnylam Pharmaceuticals?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Protagonist Therapeutics (NASDAQ:PTGX) are both healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their valuation, risk, analyst recommendations, earnings, dividends, media sentiment, profitability and institutional ownership.

In the previous week, Alnylam Pharmaceuticals had 5 more articles in the media than Protagonist Therapeutics. MarketBeat recorded 7 mentions for Alnylam Pharmaceuticals and 2 mentions for Protagonist Therapeutics. Protagonist Therapeutics' average media sentiment score of 0.83 beat Alnylam Pharmaceuticals' score of 0.19 indicating that Protagonist Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
1 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Protagonist Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Alnylam Pharmaceuticals has a beta of 0.28, meaning that its stock price is 72% less volatile than the broader market. Comparatively, Protagonist Therapeutics has a beta of 1.53, meaning that its stock price is 53% more volatile than the broader market.

93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. Comparatively, 98.6% of Protagonist Therapeutics shares are held by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are held by company insiders. Comparatively, 5.2% of Protagonist Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Alnylam Pharmaceuticals currently has a consensus price target of $366.90, indicating a potential upside of 64.48%. Protagonist Therapeutics has a consensus price target of $147.13, indicating a potential upside of 5.10%. Given Alnylam Pharmaceuticals' higher possible upside, research analysts clearly believe Alnylam Pharmaceuticals is more favorable than Protagonist Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
16 Buy rating(s)
2 Strong Buy rating(s)
2.83
Protagonist Therapeutics
0 Sell rating(s)
2 Hold rating(s)
16 Buy rating(s)
0 Strong Buy rating(s)
2.89

Alnylam Pharmaceuticals has higher revenue and earnings than Protagonist Therapeutics. Alnylam Pharmaceuticals is trading at a lower price-to-earnings ratio than Protagonist Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$3.71B8.04$313.75M$5.3841.46
Protagonist Therapeutics$46.02M196.84-$130.15M$1.03135.91

Protagonist Therapeutics has a net margin of 29.40% compared to Alnylam Pharmaceuticals' net margin of 15.26%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Protagonist Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals15.26% 84.93% 14.30%
Protagonist Therapeutics 29.40%12.03%11.23%

Summary

Alnylam Pharmaceuticals and Protagonist Therapeutics tied by winning 8 of the 16 factors compared between the two stocks.

How does Protagonist Therapeutics compare to Insmed?

Protagonist Therapeutics (NASDAQ:PTGX) and Insmed (NASDAQ:INSM) are both healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their dividends, media sentiment, risk, earnings, institutional ownership, analyst recommendations, valuation and profitability.

In the previous week, Insmed had 3 more articles in the media than Protagonist Therapeutics. MarketBeat recorded 5 mentions for Insmed and 2 mentions for Protagonist Therapeutics. Protagonist Therapeutics' average media sentiment score of 0.83 beat Insmed's score of 0.59 indicating that Protagonist Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Protagonist Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Insmed
1 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Protagonist Therapeutics has a beta of 1.53, suggesting that its share price is 53% more volatile than the broader market. Comparatively, Insmed has a beta of 0.83, suggesting that its share price is 17% less volatile than the broader market.

Protagonist Therapeutics has higher earnings, but lower revenue than Insmed. Insmed is trading at a lower price-to-earnings ratio than Protagonist Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Protagonist Therapeutics$46.02M196.84-$130.15M$1.03135.91
Insmed$606.42M39.26-$1.28B-$4.11N/A

98.6% of Protagonist Therapeutics shares are held by institutional investors. 5.2% of Protagonist Therapeutics shares are held by insiders. Comparatively, 2.1% of Insmed shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Protagonist Therapeutics has a net margin of 29.40% compared to Insmed's net margin of -76.94%. Protagonist Therapeutics' return on equity of 12.03% beat Insmed's return on equity.

Company Net Margins Return on Equity Return on Assets
Protagonist Therapeutics29.40% 12.03% 11.23%
Insmed -76.94%-123.94%-44.30%

Protagonist Therapeutics presently has a consensus price target of $147.13, suggesting a potential upside of 5.10%. Insmed has a consensus price target of $200.57, suggesting a potential upside of 83.97%. Given Insmed's stronger consensus rating and higher probable upside, analysts clearly believe Insmed is more favorable than Protagonist Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Protagonist Therapeutics
0 Sell rating(s)
2 Hold rating(s)
16 Buy rating(s)
0 Strong Buy rating(s)
2.89
Insmed
1 Sell rating(s)
0 Hold rating(s)
22 Buy rating(s)
2 Strong Buy rating(s)
3.00

Summary

Protagonist Therapeutics beats Insmed on 11 of the 17 factors compared between the two stocks.

How does Protagonist Therapeutics compare to Roivant Sciences?

Protagonist Therapeutics (NASDAQ:PTGX) and Roivant Sciences (NASDAQ:ROIV) are both healthcare companies, but which is the superior stock? We will contrast the two companies based on the strength of their earnings, risk, analyst recommendations, dividends, valuation, profitability, media sentiment and institutional ownership.

In the previous week, Roivant Sciences had 1 more articles in the media than Protagonist Therapeutics. MarketBeat recorded 3 mentions for Roivant Sciences and 2 mentions for Protagonist Therapeutics. Protagonist Therapeutics' average media sentiment score of 0.83 beat Roivant Sciences' score of -0.54 indicating that Protagonist Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Protagonist Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Roivant Sciences
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Negative

98.6% of Protagonist Therapeutics shares are held by institutional investors. Comparatively, 64.8% of Roivant Sciences shares are held by institutional investors. 5.2% of Protagonist Therapeutics shares are held by company insiders. Comparatively, 8.8% of Roivant Sciences shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Protagonist Therapeutics has a beta of 1.53, suggesting that its share price is 53% more volatile than the broader market. Comparatively, Roivant Sciences has a beta of 1.1, suggesting that its share price is 10% more volatile than the broader market.

Protagonist Therapeutics presently has a consensus price target of $147.13, indicating a potential upside of 5.10%. Roivant Sciences has a consensus price target of $45.64, indicating a potential upside of 27.83%. Given Roivant Sciences' higher probable upside, analysts clearly believe Roivant Sciences is more favorable than Protagonist Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Protagonist Therapeutics
0 Sell rating(s)
2 Hold rating(s)
16 Buy rating(s)
0 Strong Buy rating(s)
2.89
Roivant Sciences
1 Sell rating(s)
1 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.85

Protagonist Therapeutics has higher revenue and earnings than Roivant Sciences. Roivant Sciences is trading at a lower price-to-earnings ratio than Protagonist Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Protagonist Therapeutics$46.02M196.84-$130.15M$1.03135.91
Roivant Sciences$8.26M3,121.89-$299.77M-$0.53N/A

Protagonist Therapeutics has a net margin of 29.40% compared to Roivant Sciences' net margin of -3,534.96%. Protagonist Therapeutics' return on equity of 12.03% beat Roivant Sciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Protagonist Therapeutics29.40% 12.03% 11.23%
Roivant Sciences -3,534.96%-22.94%-21.53%

Summary

Protagonist Therapeutics beats Roivant Sciences on 12 of the 17 factors compared between the two stocks.

How does Protagonist Therapeutics compare to Incyte?

Protagonist Therapeutics (NASDAQ:PTGX) and Incyte (NASDAQ:INCY) are both healthcare companies, but which is the superior stock? We will contrast the two companies based on the strength of their valuation, media sentiment, analyst recommendations, risk, dividends, institutional ownership, earnings and profitability.

98.6% of Protagonist Therapeutics shares are held by institutional investors. Comparatively, 97.0% of Incyte shares are held by institutional investors. 5.2% of Protagonist Therapeutics shares are held by company insiders. Comparatively, 16.2% of Incyte shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

In the previous week, Incyte had 21 more articles in the media than Protagonist Therapeutics. MarketBeat recorded 23 mentions for Incyte and 2 mentions for Protagonist Therapeutics. Protagonist Therapeutics' average media sentiment score of 0.83 beat Incyte's score of 0.62 indicating that Protagonist Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Protagonist Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Incyte
7 Very Positive mention(s)
4 Positive mention(s)
9 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Protagonist Therapeutics has a net margin of 29.40% compared to Incyte's net margin of 27.71%. Incyte's return on equity of 29.93% beat Protagonist Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Protagonist Therapeutics29.40% 12.03% 11.23%
Incyte 27.71%29.93%22.88%

Incyte has higher revenue and earnings than Protagonist Therapeutics. Incyte is trading at a lower price-to-earnings ratio than Protagonist Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Protagonist Therapeutics$46.02M196.84-$130.15M$1.03135.91
Incyte$5.14B4.59$1.29B$7.8514.81

Protagonist Therapeutics has a beta of 1.53, meaning that its stock price is 53% more volatile than the broader market. Comparatively, Incyte has a beta of 0.74, meaning that its stock price is 26% less volatile than the broader market.

Protagonist Therapeutics currently has a consensus price target of $147.13, suggesting a potential upside of 5.10%. Incyte has a consensus price target of $126.15, suggesting a potential upside of 8.48%. Given Incyte's higher possible upside, analysts plainly believe Incyte is more favorable than Protagonist Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Protagonist Therapeutics
0 Sell rating(s)
2 Hold rating(s)
16 Buy rating(s)
0 Strong Buy rating(s)
2.89
Incyte
0 Sell rating(s)
12 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.56

Summary

Incyte beats Protagonist Therapeutics on 9 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PTGX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PTGX vs. The Competition

MetricProtagonist TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$9.04B$3.84B$7.13B$13.27B
Dividend YieldN/A3.64%2.53%15.88%
P/E Ratio135.5913.60273.9926.15
Price / Sales196.841,296.00608.6593.06
Price / CashN/A121.7677.3851.25
Price / Book14.2416.5710.886.34
Net Income-$130.15M-$22.67M$3.50B$361.18M
7 Day Performance-1.31%-2.20%-1.62%-1.17%
1 Month Performance-4.16%-10.00%-5.90%-3.40%
1 Year Performance115.45%22.34%9.47%3.28%

Protagonist Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PTGX
Protagonist Therapeutics
1.675 of 5 stars
$140.29
+0.8%
$147.13
+4.9%
+117.5%$9.07B$46.02M136.05141
BIIB
Biogen
2.8098 of 5 stars
$227.60
+0.5%
$230.14
+1.1%
+44.5%$33.45B$9.89B40.287,500
ALNY
Alnylam Pharmaceuticals
3.9168 of 5 stars
$255.96
+2.6%
$367.20
+43.5%
-49.8%$33.40B$3.71B47.582,770
INSM
Insmed
3.6153 of 5 stars
$117.83
-3.1%
$201.87
+71.3%
-26.3%$26.54B$606.42MN/A1,664
ROIV
Roivant Sciences
2.6368 of 5 stars
$35.80
-0.9%
$45.64
+27.5%
+125.4%$26.10B$8.26MN/A721

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This page (NASDAQ:PTGX) was last updated on 10/2/2026 by MarketBeat.com Staff.
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