Protagonist Therapeutics (PTGX) Institutional Ownership

$99.56 -0.85 (-0.85%)

Closing price 04:00 PM Eastern

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$99.61 +0.05 (+0.05%)

As of 07:57 PM Eastern

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Current Institutional Ownership Percentage: 98.63%
Number of Institutional Buyers (last 12 months): 224
Total Institutional Inflows (last 12 months): $1.77B

Number of Institutional Sellers (last 12 months): 125
Total Institutional Outflows (last 12 months): $659.67M

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PTGX Institutional Buying and Selling by Quarter

Protagonist Therapeutics Major Shareholders & Ownership History

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Reporting Date	Major Shareholder Name	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
5/29/2026	Perceptive Advisors LLC	1,230,879	$129.74M	2.5%	-8.9%	1.914%
5/26/2026	Glenmede Trust Co. NA	9,235	$973K	0.0%	-27.6%	0.014%
5/26/2026	Axiom Investment Management LLC	2,000	$211K	0.2%	N/A	0.003%
5/22/2026	Segall Bryant & Hamill LLC	212,714	$22.42M	0.3%	+64.8%	0.331%
5/19/2026	Bank of America Corp DE	1,295,434	$136.54M	0.0%	+49.3%	2.014%
5/19/2026	Stempoint Capital LP	72,577	$7.65M	1.5%	+22.1%	0.113%
5/19/2026	Janus Henderson Group PLC	2,891,527	$304.87M	0.1%	+9.1%	4.496%
5/18/2026	ADAR1 Capital Management LLC	994,119	$104.78M	6.2%	-5.2%	1.546%
5/18/2026	Amundi	4,113	$434K	0.0%	N/A	0.006%
5/18/2026	EverSource Wealth Advisors LLC	911	$96K	0.0%	+63.0%	0.001%
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5/18/2026	California State Teachers Retirement System	58,677	$6.19M	0.0%	+22.2%	0.091%
5/18/2026	Royal Bank of Canada	1,599	$169K	0.0%	-49.8%	0.002%
5/18/2026	Rubric Capital Management LP	427,998	$45.11M	0.5%	N/A	0.666%
5/18/2026	Eagle Health Investments LP	179,322	$18.90M	3.3%	+213.0%	0.279%
5/18/2026	Empowered Funds LLC	2,321	$245K	0.0%	N/A	0.004%
5/16/2026	The Manufacturers Life Insurance Company	127,818	$13.47M	0.0%	+12.8%	0.199%
5/16/2026	Quantinno Capital Management LP	6,437	$678K	0.0%	+30.1%	0.010%
5/16/2026	Orbimed Advisors LLC	42,100	$4.44M	0.1%	+94.0%	0.065%
5/15/2026	Weiss Asset Management LP	9,780	$1.03M	0.0%	N/A	0.015%
5/15/2026	Granahan Investment Management LLC	27,391	$2.89M	0.1%	N/A	0.043%
5/14/2026	Gabelli Funds LLC	3,229	$340K	0.0%	N/A	0.005%
5/14/2026	Atika Capital Management LLC	62,100	$6.55M	0.8%	-27.8%	0.097%
5/14/2026	Knott David M Jr	63,000	$6.64M	3.9%	-13.7%	0.098%
5/14/2026	Sei Investments Co.	83,197	$8.77M	0.0%	+122.8%	0.129%
5/13/2026	First Trust Advisors LP	87,858	$9.26M	0.0%	+89.1%	0.137%
5/8/2026	PNC Financial Services Group Inc.	3,998	$421K	0.0%	+35.1%	0.006%
5/7/2026	Dimensional Fund Advisors LP	508,103	$53.54M	0.0%	+22.6%	0.790%
5/7/2026	AlphaCentric Advisors LLC	9,040	$953K	1.0%	+5.7%	0.014%
5/7/2026	SEB Asset Management AB	232,416	$24.50M	0.1%	N/A	0.361%
5/7/2026	Swiss National Bank	98,900	$10.42M	0.0%	+0.7%	0.154%
5/6/2026	Jennison Associates LLC	1,072,011	$112.99M	0.1%	+223.7%	1.667%
5/6/2026	Assetmark Inc.	46,442	$4.90M	0.0%	+16,195.4%	0.072%
5/6/2026	Allspring Global Investments Holdings LLC	29,916	$3.10M	0.0%	+650.7%	0.047%
5/5/2026	Bank of New York Mellon Corp	341,465	$35.99M	0.0%	-2.5%	0.531%
5/5/2026	Illinois Municipal Retirement Fund	28,596	$3.01M	0.0%	-8.5%	0.044%
5/4/2026	Calamos Advisors LLC	23,473	$2.47M	0.0%	N/A	0.036%
5/4/2026	Bleakley Financial Group LLC	12,802	$1.35M	0.0%	N/A	0.020%
5/4/2026	Principal Financial Group Inc.	367,822	$38.77M	0.0%	+5.7%	0.572%
5/1/2026	Fifth Third Bancorp	13,202	$1.39M	0.0%	+3,937.3%	0.021%
4/30/2026	Hsbc Holdings PLC	1,907	$201K	0.0%	N/A	0.003%
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4/30/2026	Sumitomo Mitsui Trust Group Inc.	2,760	$291K	0.0%	+7.8%	0.004%
4/29/2026	Burney Co.	3,179	$335K	0.0%	-13.6%	0.005%
4/28/2026	Abel Hall LLC	4,258	$449K	0.1%	N/A	0.007%
4/27/2026	New York State Teachers Retirement System	47,424	$5.00M	0.0%	-3.9%	0.074%
4/25/2026	Strs Ohio	15,400	$1.62M	0.0%	-3.1%	0.024%
4/25/2026	Keybank National Association OH	4,286	$452K	0.0%	N/A	0.007%
4/23/2026	Inspire Investing LLC	5,036	$531K	0.0%	-7.8%	0.008%
4/22/2026	Pictet Asset Management Holding SA	581,083	$61.25M	0.1%	+9.7%	0.911%
4/21/2026	Louisiana State Employees Retirement System	26,100	$2.75M	0.0%	N/A	0.041%
4/16/2026	SG Americas Securities LLC	18,097	$1.91M	0.0%	-9.5%	0.028%
3/17/2026	Rockefeller Capital Management L.P.	3,292	$288K	0.0%	+10.5%	0.005%
2/26/2026	Seven Fleet Capital Management LP	8,000	$699K	0.5%	N/A	0.013%
2/19/2026	Invesco Ltd.	1,567,840	$136.94M	0.0%	+56.2%	2.508%
2/18/2026	Vident Advisory LLC	4,191	$366K	0.0%	-17.3%	0.007%
2/18/2026	State of Tennessee Department of Treasury	23,526	$1.92M	0.0%	-11.2%	0.038%
2/18/2026	Mackenzie Financial Corp	3,648	$318K	0.0%	-10.2%	0.006%
2/18/2026	KVP Capital Advisors LP	53,000	$4.63M	4.5%	N/A	0.085%
2/18/2026	Virtus Investment Advisers LLC	2,790	$244K	0.1%	+38.1%	0.004%
2/18/2026	Wellington Management Group LLP	3,171,423	$276.99M	0.1%	+66.2%	5.073%
2/18/2026	SummitTX Capital L.P.	42,266	$3.69M	0.1%	+34.2%	0.068%
2/18/2026	RTW Investments LP	5,059,053	$441.86M	4.4%	-12.1%	8.092%
2/18/2026	Orbimed Advisors LLC	21,700	$1.90M	0.0%	N/A	0.035%
2/18/2026	Perceptive Advisors LLC	1,350,425	$117.95M	2.1%	+31.1%	2.160%
2/18/2026	Millennium Management LLC	17,391	$1.52M	0.0%	-86.4%	0.028%
2/18/2026	Inspire Investing LLC	5,460	$477K	0.0%	-21.3%	0.009%
2/18/2026	Janus Henderson Group PLC	2,649,981	$231.36M	0.1%	+140.7%	4.239%
2/18/2026	Gotham Asset Management LLC	21,595	$1.89M	0.0%	-2.7%	0.035%
2/18/2026	Elmind Capital LP	38,000	$3.32M	1.0%	N/A	0.061%
2/18/2026	Eversept Partners LP	52,961	$4.63M	0.2%	N/A	0.085%
2/18/2026	Commodore Capital LP	450,000	$39.30M	2.6%	-56.1%	0.720%
2/18/2026	Bamco Inc. NY	8,300	$725K	0.0%	N/A	0.013%
2/17/2026	Guggenheim Capital LLC	31,096	$2.72M	0.0%	+67.3%	0.050%
2/17/2026	ADAR1 Capital Management LLC	1,049,168	$91.63M	6.7%	+6.1%	1.678%
2/17/2026	AQR Capital Management LLC	6,954	$607K	0.0%	-18.9%	0.011%
2/17/2026	EFG International AG	72,623	$6.34M	0.1%	N/A	0.116%
2/17/2026	MPM Bioimpact LLC	199,471	$17.42M	2.0%	N/A	0.319%
2/17/2026	Jain Global LLC	12,850	$1.12M	0.0%	-13.5%	0.021%
2/17/2026	Pentwater Capital Management LP	50,000	$4.37M	0.0%	N/A	0.080%
2/17/2026	Farallon Capital Management LLC	6,144,006	$536.62M	2.5%	-0.8%	9.827%
2/17/2026	Price T Rowe Associates Inc. MD	1,400,738	$122.34M	0.0%	+14.8%	2.240%
2/17/2026	Osaic Holdings Inc.	4,201	$367K	0.0%	+202.0%	0.007%
2/17/2026	Adage Capital Partners GP L.L.C.	232,836	$20.34M	0.0%	-67.6%	0.372%
2/17/2026	California State Teachers Retirement System	48,033	$4.20M	0.0%	+1.3%	0.077%
2/17/2026	Diadema Partners LP	22,700	$1.98M	0.3%	-55.7%	0.036%
2/17/2026	Russell Investments Group Ltd.	5,723	$500K	0.0%	-3.4%	0.009%
2/17/2026	Maryland State Retirement & Pension System	8,603	$751K	0.0%	+2.3%	0.014%
2/17/2026	State of Wisconsin Investment Board	34,786	$3.04M	0.0%	-15.0%	0.056%
2/17/2026	Captrust Financial Advisors	2,732	$239K	0.0%	-17.5%	0.004%
2/17/2026	Royal Bank of Canada	3,183	$278K	0.0%	-95.5%	0.005%
2/17/2026	Persistent Asset Partners Ltd	7,908	$691K	0.3%	-32.9%	0.013%
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2/16/2026	Truvestments Capital LLC	1,161	$101K	0.0%	+60.8%	0.002%
2/16/2026	Panagora Asset Management Inc.	125,384	$10.95M	0.0%	-15.7%	0.201%
2/16/2026	Mariner LLC	7,620	$666K	0.0%	-43.8%	0.012%
2/16/2026	NEXTBio Capital Management LP	229,619	$20.06M	11.8%	N/A	0.367%
2/16/2026	Fieldview Capital Management LLC	5,841	$510K	0.1%	N/A	0.009%
2/16/2026	Kennedy Capital Management LLC	221,444	$19.34M	0.4%	+6.2%	0.354%
2/16/2026	Dymon Asia Capital Singapore PTE. LTD.	10,000	$873K	0.1%	N/A	0.016%
2/16/2026	Barclays PLC	187,642	$16.39M	0.0%	+9.5%	0.300%
2/13/2026	FORA Capital LLC	9,130	$788K	0.1%	+147.8%	0.015%
2/13/2026	Marshall Wace LLP	1,024,925	$89.52M	0.1%	-5.6%	1.639%

PTGX Institutional Ownership - Frequently Asked Questions

During the previous two years, 344 institutional investors and hedge funds held shares of Protagonist Therapeutics. The most heavily invested institutionals were Farallon Capital Management LLC ($536.62M), Vanguard Group Inc. ($472.83M), RTW Investments LP ($441.86M), Janus Henderson Group PLC ($304.87M), State Street Corp ($279.46M), Wellington Management Group LLP ($276.99M), and UBS Group AG ($241.93M).Learn more on Protagonist Therapeutics' institutional investors.

98.63% of Protagonist Therapeutics' stock is owned by institutional investors. Learn more on PTGX's institutional investor holdings.

Of the 311 institutional investors that purchased Protagonist Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Wellington Management Group LLP ($4.03M), Pacer Advisors Inc. ($1.88M), Janus Henderson Group PLC ($1.79M), State Street Corp ($1.64M), BVF Inc. IL ($1.36M), Vanguard Group Inc. ($1.22M), and Millennium Management LLC ($1.13M).

Institutional investors have bought a total of 22,848,320 shares in the last 24 months. This purchase volume represents approximately $1.77B in transactions.

Of the 125 institutional investors that sold Protagonist Therapeutics' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Deep Track Capital LP ($1.53M), Jefferies Financial Group Inc. ($819.02K), RTW Investments LP ($697.22K), Commodore Capital LP ($625K), UBS Group AG ($605.24K), Adage Capital Partners GP L.L.C. ($485.37K), and JPMorgan Chase & Co. ($471.68K).

Institutional investors have sold a total of 8,850,482 shares in the last 24 months. This volume of shares sold represents approximately $659.67M in transactions.

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This page (NASDAQ:PTGX) was last updated on 5/29/2026 by MarketBeat.com Staff.

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Protagonist Therapeutics (PTGX) Institutional Ownership

PTGX Institutional Buying and Selling by Quarter

Protagonist Therapeutics Major Shareholders & Ownership History

PTGX Institutional Ownership - Frequently Asked Questions

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Protagonist Therapeutics (PTGX) Institutional Ownership

Institutional Ownership Changes (13F Filings) for Protagonist Therapeutics (NASDAQ:PTGX)

PTGX Institutional Buying and Selling by Quarter

Protagonist Therapeutics Major Shareholders & Ownership History

PTGX Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of PTGX shares?

What percentage of Protagonist Therapeutics' stock is owned by institutional investors?

Which institutional investors have been buying Protagonist Therapeutics' stock?

How much institutional buying is happening at Protagonist Therapeutics?

Which of Protagonist Therapeutics' major shareholders have been selling company stock?

How much institutional selling is happening at Protagonist Therapeutics?

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