Madrigal Pharmaceuticals (MDGL) Competitors

Madrigal Pharmaceuticals logo
$513.43 +0.55 (+0.11%)
Closing price 04:00 PM Eastern
Extended Trading
$500.00 -13.43 (-2.62%)
As of 06:11 PM Eastern
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MDGL vs. ALNY, BIIB, UTHR, INCY, and NBIX

Should you buy Madrigal Pharmaceuticals stock or one of its competitors? MarketBeat compares Madrigal Pharmaceuticals with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Madrigal Pharmaceuticals include Alnylam Pharmaceuticals (ALNY), Biogen (BIIB), United Therapeutics (UTHR), Incyte (INCY), and Neurocrine Biosciences (NBIX). These companies are all part of the "biotechnology" industry.

How does Madrigal Pharmaceuticals compare to Alnylam Pharmaceuticals?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Madrigal Pharmaceuticals (NASDAQ:MDGL) are both large-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their earnings, risk, analyst recommendations, profitability, institutional ownership, dividends, media sentiment and valuation.

Alnylam Pharmaceuticals has higher revenue and earnings than Madrigal Pharmaceuticals. Madrigal Pharmaceuticals is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$3.71B10.36$313.75M$3.6678.74
Madrigal Pharmaceuticals$958.40M12.35-$288.28M-$12.80N/A

Alnylam Pharmaceuticals presently has a consensus price target of $463.13, suggesting a potential upside of 60.71%. Madrigal Pharmaceuticals has a consensus price target of $687.93, suggesting a potential upside of 33.99%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, equities research analysts plainly believe Alnylam Pharmaceuticals is more favorable than Madrigal Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85
Madrigal Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.78

In the previous week, Alnylam Pharmaceuticals had 11 more articles in the media than Madrigal Pharmaceuticals. MarketBeat recorded 17 mentions for Alnylam Pharmaceuticals and 6 mentions for Madrigal Pharmaceuticals. Madrigal Pharmaceuticals' average media sentiment score of 1.28 beat Alnylam Pharmaceuticals' score of 0.80 indicating that Madrigal Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
10 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Positive
Madrigal Pharmaceuticals
5 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Alnylam Pharmaceuticals has a beta of 0.29, suggesting that its share price is 71% less volatile than the broader market. Comparatively, Madrigal Pharmaceuticals has a beta of -1.07, suggesting that its share price is 207% less volatile than the broader market.

Alnylam Pharmaceuticals has a net margin of 11.72% compared to Madrigal Pharmaceuticals' net margin of -27.32%. Alnylam Pharmaceuticals' return on equity of 85.76% beat Madrigal Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals11.72% 85.76% 10.32%
Madrigal Pharmaceuticals -27.32%-50.15%-25.44%

93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. Comparatively, 98.5% of Madrigal Pharmaceuticals shares are owned by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are owned by company insiders. Comparatively, 17.6% of Madrigal Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Summary

Alnylam Pharmaceuticals beats Madrigal Pharmaceuticals on 13 of the 17 factors compared between the two stocks.

How does Madrigal Pharmaceuticals compare to Biogen?

Madrigal Pharmaceuticals (NASDAQ:MDGL) and Biogen (NASDAQ:BIIB) are both large-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their analyst recommendations, institutional ownership, profitability, earnings, dividends, risk, valuation and media sentiment.

Madrigal Pharmaceuticals currently has a consensus target price of $687.93, suggesting a potential upside of 33.99%. Biogen has a consensus target price of $217.37, suggesting a potential upside of 10.23%. Given Madrigal Pharmaceuticals' stronger consensus rating and higher probable upside, equities research analysts plainly believe Madrigal Pharmaceuticals is more favorable than Biogen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Madrigal Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.78
Biogen
1 Sell rating(s)
12 Hold rating(s)
16 Buy rating(s)
1 Strong Buy rating(s)
2.57

Biogen has a net margin of 13.81% compared to Madrigal Pharmaceuticals' net margin of -27.32%. Biogen's return on equity of 12.83% beat Madrigal Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Madrigal Pharmaceuticals-27.32% -50.15% -25.44%
Biogen 13.81%12.83%8.01%

98.5% of Madrigal Pharmaceuticals shares are owned by institutional investors. Comparatively, 87.9% of Biogen shares are owned by institutional investors. 17.6% of Madrigal Pharmaceuticals shares are owned by company insiders. Comparatively, 0.3% of Biogen shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Biogen has higher revenue and earnings than Madrigal Pharmaceuticals. Madrigal Pharmaceuticals is trading at a lower price-to-earnings ratio than Biogen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Madrigal Pharmaceuticals$958.40M12.35-$288.28M-$12.80N/A
Biogen$9.89B2.94$1.29B$9.3221.16

Madrigal Pharmaceuticals has a beta of -1.07, meaning that its stock price is 207% less volatile than the broader market. Comparatively, Biogen has a beta of 0.2, meaning that its stock price is 80% less volatile than the broader market.

In the previous week, Biogen had 20 more articles in the media than Madrigal Pharmaceuticals. MarketBeat recorded 26 mentions for Biogen and 6 mentions for Madrigal Pharmaceuticals. Madrigal Pharmaceuticals' average media sentiment score of 1.28 beat Biogen's score of 0.98 indicating that Madrigal Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Madrigal Pharmaceuticals
5 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Biogen
14 Very Positive mention(s)
5 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Biogen beats Madrigal Pharmaceuticals on 10 of the 16 factors compared between the two stocks.

How does Madrigal Pharmaceuticals compare to United Therapeutics?

Madrigal Pharmaceuticals (NASDAQ:MDGL) and United Therapeutics (NASDAQ:UTHR) are both large-cap medical companies, but which is the superior business? We will compare the two companies based on the strength of their analyst recommendations, valuation, dividends, media sentiment, institutional ownership, profitability, earnings and risk.

United Therapeutics has a net margin of 40.62% compared to Madrigal Pharmaceuticals' net margin of -27.32%. United Therapeutics' return on equity of 19.24% beat Madrigal Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Madrigal Pharmaceuticals-27.32% -50.15% -25.44%
United Therapeutics 40.62%19.24%17.25%

Madrigal Pharmaceuticals has a beta of -1.07, meaning that its share price is 207% less volatile than the broader market. Comparatively, United Therapeutics has a beta of 0.57, meaning that its share price is 43% less volatile than the broader market.

98.5% of Madrigal Pharmaceuticals shares are owned by institutional investors. Comparatively, 94.1% of United Therapeutics shares are owned by institutional investors. 17.6% of Madrigal Pharmaceuticals shares are owned by company insiders. Comparatively, 8.6% of United Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

United Therapeutics has higher revenue and earnings than Madrigal Pharmaceuticals. Madrigal Pharmaceuticals is trading at a lower price-to-earnings ratio than United Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Madrigal Pharmaceuticals$958.40M12.35-$288.28M-$12.80N/A
United Therapeutics$3.18B7.26$1.33B$27.0920.09

Madrigal Pharmaceuticals presently has a consensus price target of $687.93, suggesting a potential upside of 33.99%. United Therapeutics has a consensus price target of $619.42, suggesting a potential upside of 13.79%. Given Madrigal Pharmaceuticals' higher possible upside, equities research analysts clearly believe Madrigal Pharmaceuticals is more favorable than United Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Madrigal Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.78
United Therapeutics
0 Sell rating(s)
2 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.85

In the previous week, United Therapeutics had 13 more articles in the media than Madrigal Pharmaceuticals. MarketBeat recorded 19 mentions for United Therapeutics and 6 mentions for Madrigal Pharmaceuticals. Madrigal Pharmaceuticals' average media sentiment score of 1.28 beat United Therapeutics' score of 0.70 indicating that Madrigal Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Madrigal Pharmaceuticals
5 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
United Therapeutics
13 Very Positive mention(s)
2 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

United Therapeutics beats Madrigal Pharmaceuticals on 10 of the 17 factors compared between the two stocks.

How does Madrigal Pharmaceuticals compare to Incyte?

Madrigal Pharmaceuticals (NASDAQ:MDGL) and Incyte (NASDAQ:INCY) are both large-cap medical companies, but which is the superior stock? We will contrast the two companies based on the strength of their media sentiment, valuation, analyst recommendations, earnings, risk, institutional ownership, profitability and dividends.

In the previous week, Incyte had 5 more articles in the media than Madrigal Pharmaceuticals. MarketBeat recorded 11 mentions for Incyte and 6 mentions for Madrigal Pharmaceuticals. Madrigal Pharmaceuticals' average media sentiment score of 1.28 beat Incyte's score of 0.90 indicating that Madrigal Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Madrigal Pharmaceuticals
5 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Incyte
6 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

98.5% of Madrigal Pharmaceuticals shares are held by institutional investors. Comparatively, 97.0% of Incyte shares are held by institutional investors. 17.6% of Madrigal Pharmaceuticals shares are held by company insiders. Comparatively, 16.2% of Incyte shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Madrigal Pharmaceuticals has a beta of -1.07, meaning that its share price is 207% less volatile than the broader market. Comparatively, Incyte has a beta of 0.79, meaning that its share price is 21% less volatile than the broader market.

Incyte has a net margin of 26.71% compared to Madrigal Pharmaceuticals' net margin of -27.32%. Incyte's return on equity of 26.66% beat Madrigal Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Madrigal Pharmaceuticals-27.32% -50.15% -25.44%
Incyte 26.71%26.66%19.77%

Incyte has higher revenue and earnings than Madrigal Pharmaceuticals. Madrigal Pharmaceuticals is trading at a lower price-to-earnings ratio than Incyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Madrigal Pharmaceuticals$958.40M12.35-$288.28M-$12.80N/A
Incyte$5.14B4.06$1.29B$7.0814.75

Madrigal Pharmaceuticals currently has a consensus target price of $687.93, indicating a potential upside of 33.99%. Incyte has a consensus target price of $106.90, indicating a potential upside of 2.39%. Given Madrigal Pharmaceuticals' stronger consensus rating and higher probable upside, research analysts plainly believe Madrigal Pharmaceuticals is more favorable than Incyte.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Madrigal Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.78
Incyte
0 Sell rating(s)
14 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.36

Summary

Incyte beats Madrigal Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Madrigal Pharmaceuticals compare to Neurocrine Biosciences?

Madrigal Pharmaceuticals (NASDAQ:MDGL) and Neurocrine Biosciences (NASDAQ:NBIX) are both large-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their earnings, analyst recommendations, dividends, institutional ownership, valuation, risk, media sentiment and profitability.

Neurocrine Biosciences has a net margin of 21.55% compared to Madrigal Pharmaceuticals' net margin of -27.32%. Neurocrine Biosciences' return on equity of 19.79% beat Madrigal Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Madrigal Pharmaceuticals-27.32% -50.15% -25.44%
Neurocrine Biosciences 21.55%19.79%13.82%

Neurocrine Biosciences has higher revenue and earnings than Madrigal Pharmaceuticals. Madrigal Pharmaceuticals is trading at a lower price-to-earnings ratio than Neurocrine Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Madrigal Pharmaceuticals$958.40M12.35-$288.28M-$12.80N/A
Neurocrine Biosciences$2.86B5.67$478.60M$6.4924.88

98.5% of Madrigal Pharmaceuticals shares are held by institutional investors. Comparatively, 92.6% of Neurocrine Biosciences shares are held by institutional investors. 17.6% of Madrigal Pharmaceuticals shares are held by insiders. Comparatively, 4.6% of Neurocrine Biosciences shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

In the previous week, Madrigal Pharmaceuticals had 2 more articles in the media than Neurocrine Biosciences. MarketBeat recorded 6 mentions for Madrigal Pharmaceuticals and 4 mentions for Neurocrine Biosciences. Madrigal Pharmaceuticals' average media sentiment score of 1.28 beat Neurocrine Biosciences' score of 0.70 indicating that Madrigal Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Madrigal Pharmaceuticals
5 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Neurocrine Biosciences
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Madrigal Pharmaceuticals currently has a consensus price target of $687.93, suggesting a potential upside of 33.99%. Neurocrine Biosciences has a consensus price target of $187.52, suggesting a potential upside of 16.16%. Given Madrigal Pharmaceuticals' higher possible upside, equities research analysts clearly believe Madrigal Pharmaceuticals is more favorable than Neurocrine Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Madrigal Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.78
Neurocrine Biosciences
0 Sell rating(s)
4 Hold rating(s)
18 Buy rating(s)
1 Strong Buy rating(s)
2.87

Madrigal Pharmaceuticals has a beta of -1.07, meaning that its share price is 207% less volatile than the broader market. Comparatively, Neurocrine Biosciences has a beta of 0.4, meaning that its share price is 60% less volatile than the broader market.

Summary

Neurocrine Biosciences beats Madrigal Pharmaceuticals on 10 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding MDGL and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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MDGL vs. The Competition

MetricMadrigal PharmaceuticalsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$11.82B$2.97B$6.45B$12.39B
Dividend YieldN/A1.80%2.69%5.83%
P/E Ratio-40.1118.4324.9223.98
Price / Sales12.35327.41528.51109.04
Price / CashN/A56.3144.8254.51
Price / Book19.354.1110.796.50
Net Income-$288.28M$64.45M$3.56B$336.88M
7 Day Performance2.44%2.24%1.67%-0.22%
1 Month Performance-0.74%1.04%0.43%0.77%
1 Year Performance81.43%30.05%32.84%31.57%

Madrigal Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
MDGL
Madrigal Pharmaceuticals
3.5777 of 5 stars
$513.43
+0.1%
$687.93
+34.0%
+79.5%$11.82B$958.40MN/A90
ALNY
Alnylam Pharmaceuticals
4.4125 of 5 stars
$287.80
+1.8%
$463.13
+60.9%
-7.5%$37.76B$3.71B78.632,770
BIIB
Biogen
3.9134 of 5 stars
$198.64
-0.7%
$216.70
+9.1%
+57.2%$29.53B$9.89B21.317,500
UTHR
United Therapeutics
4.2372 of 5 stars
$549.57
+0.7%
$619.42
+12.7%
+85.1%$23.17B$3.18B20.291,400
INCY
Incyte
3.9009 of 5 stars
$101.98
-6.0%
$105.10
+3.1%
+51.4%$21.68B$5.14B14.402,844

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This page (NASDAQ:MDGL) was last updated on 6/23/2026 by MarketBeat.com Staff.
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