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Madrigal Pharmaceuticals (MDGL) Competitors

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$488.15 +35.29 (+7.79%)
Closing price 04:00 PM Eastern
Extended Trading
$484.74 -3.41 (-0.70%)
As of 05:10 PM Eastern
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MDGL vs. ALNY, BIIB, UTHR, INCY, and NBIX

Should you buy Madrigal Pharmaceuticals stock or one of its competitors? MarketBeat compares Madrigal Pharmaceuticals with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Madrigal Pharmaceuticals include Alnylam Pharmaceuticals (ALNY), Biogen (BIIB), United Therapeutics (UTHR), Incyte (INCY), and Neurocrine Biosciences (NBIX). These companies are all part of the "biotechnology" industry.

How does Madrigal Pharmaceuticals compare to Alnylam Pharmaceuticals?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Madrigal Pharmaceuticals (NASDAQ:MDGL) are both large-cap medical companies, but which is the better business? We will contrast the two businesses based on the strength of their risk, valuation, profitability, earnings, analyst recommendations, media sentiment, institutional ownership and dividends.

In the previous week, Alnylam Pharmaceuticals had 5 more articles in the media than Madrigal Pharmaceuticals. MarketBeat recorded 16 mentions for Alnylam Pharmaceuticals and 11 mentions for Madrigal Pharmaceuticals. Alnylam Pharmaceuticals' average media sentiment score of 1.61 beat Madrigal Pharmaceuticals' score of 0.68 indicating that Alnylam Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
11 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Madrigal Pharmaceuticals
3 Very Positive mention(s)
3 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Alnylam Pharmaceuticals presently has a consensus price target of $463.13, suggesting a potential upside of 58.29%. Madrigal Pharmaceuticals has a consensus price target of $687.00, suggesting a potential upside of 40.74%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, equities research analysts plainly believe Alnylam Pharmaceuticals is more favorable than Madrigal Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85
Madrigal Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.78

Alnylam Pharmaceuticals has higher revenue and earnings than Madrigal Pharmaceuticals. Madrigal Pharmaceuticals is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$3.71B10.52$313.75M$3.6679.94
Madrigal Pharmaceuticals$958.40M11.75-$288.28M-$12.80N/A

93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. Comparatively, 98.5% of Madrigal Pharmaceuticals shares are owned by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are owned by company insiders. Comparatively, 17.6% of Madrigal Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Alnylam Pharmaceuticals has a net margin of 11.72% compared to Madrigal Pharmaceuticals' net margin of -27.32%. Alnylam Pharmaceuticals' return on equity of 85.76% beat Madrigal Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals11.72% 85.76% 10.32%
Madrigal Pharmaceuticals -27.32%-50.15%-25.44%

Alnylam Pharmaceuticals has a beta of 0.29, meaning that its stock price is 71% less volatile than the broader market. Comparatively, Madrigal Pharmaceuticals has a beta of -1.07, meaning that its stock price is 207% less volatile than the broader market.

Summary

Alnylam Pharmaceuticals beats Madrigal Pharmaceuticals on 14 of the 17 factors compared between the two stocks.

How does Madrigal Pharmaceuticals compare to Biogen?

Madrigal Pharmaceuticals (NASDAQ:MDGL) and Biogen (NASDAQ:BIIB) are both large-cap medical companies, but which is the better stock? We will contrast the two companies based on the strength of their media sentiment, profitability, institutional ownership, valuation, earnings, dividends, analyst recommendations and risk.

Biogen has higher revenue and earnings than Madrigal Pharmaceuticals. Madrigal Pharmaceuticals is trading at a lower price-to-earnings ratio than Biogen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Madrigal Pharmaceuticals$958.40M11.75-$288.28M-$12.80N/A
Biogen$9.89B2.93$1.29B$9.3221.03

Biogen has a net margin of 13.81% compared to Madrigal Pharmaceuticals' net margin of -27.32%. Biogen's return on equity of 12.83% beat Madrigal Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Madrigal Pharmaceuticals-27.32% -50.15% -25.44%
Biogen 13.81%12.83%8.01%

98.5% of Madrigal Pharmaceuticals shares are held by institutional investors. Comparatively, 87.9% of Biogen shares are held by institutional investors. 17.6% of Madrigal Pharmaceuticals shares are held by company insiders. Comparatively, 0.3% of Biogen shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Madrigal Pharmaceuticals has a beta of -1.07, meaning that its stock price is 207% less volatile than the broader market. Comparatively, Biogen has a beta of 0.2, meaning that its stock price is 80% less volatile than the broader market.

In the previous week, Biogen had 6 more articles in the media than Madrigal Pharmaceuticals. MarketBeat recorded 17 mentions for Biogen and 11 mentions for Madrigal Pharmaceuticals. Madrigal Pharmaceuticals' average media sentiment score of 0.68 beat Biogen's score of 0.25 indicating that Madrigal Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Madrigal Pharmaceuticals
3 Very Positive mention(s)
3 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Biogen
2 Very Positive mention(s)
2 Positive mention(s)
11 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

Madrigal Pharmaceuticals currently has a consensus price target of $687.00, indicating a potential upside of 40.74%. Biogen has a consensus price target of $215.81, indicating a potential upside of 10.13%. Given Madrigal Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Madrigal Pharmaceuticals is more favorable than Biogen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Madrigal Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.78
Biogen
1 Sell rating(s)
13 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.52

Summary

Biogen beats Madrigal Pharmaceuticals on 10 of the 16 factors compared between the two stocks.

How does Madrigal Pharmaceuticals compare to United Therapeutics?

Madrigal Pharmaceuticals (NASDAQ:MDGL) and United Therapeutics (NASDAQ:UTHR) are both large-cap medical companies, but which is the better business? We will compare the two companies based on the strength of their media sentiment, profitability, valuation, dividends, earnings, analyst recommendations, institutional ownership and risk.

Madrigal Pharmaceuticals has a beta of -1.07, indicating that its stock price is 207% less volatile than the broader market. Comparatively, United Therapeutics has a beta of 0.57, indicating that its stock price is 43% less volatile than the broader market.

In the previous week, United Therapeutics had 9 more articles in the media than Madrigal Pharmaceuticals. MarketBeat recorded 20 mentions for United Therapeutics and 11 mentions for Madrigal Pharmaceuticals. Madrigal Pharmaceuticals' average media sentiment score of 0.68 beat United Therapeutics' score of 0.48 indicating that Madrigal Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Madrigal Pharmaceuticals
3 Very Positive mention(s)
3 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
United Therapeutics
10 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

98.5% of Madrigal Pharmaceuticals shares are owned by institutional investors. Comparatively, 94.1% of United Therapeutics shares are owned by institutional investors. 17.6% of Madrigal Pharmaceuticals shares are owned by insiders. Comparatively, 8.6% of United Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

United Therapeutics has higher revenue and earnings than Madrigal Pharmaceuticals. Madrigal Pharmaceuticals is trading at a lower price-to-earnings ratio than United Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Madrigal Pharmaceuticals$958.40M11.75-$288.28M-$12.80N/A
United Therapeutics$3.18B7.33$1.33B$27.0920.28

United Therapeutics has a net margin of 40.62% compared to Madrigal Pharmaceuticals' net margin of -27.32%. United Therapeutics' return on equity of 19.24% beat Madrigal Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Madrigal Pharmaceuticals-27.32% -50.15% -25.44%
United Therapeutics 40.62%19.24%17.25%

Madrigal Pharmaceuticals currently has a consensus target price of $687.00, suggesting a potential upside of 40.74%. United Therapeutics has a consensus target price of $619.42, suggesting a potential upside of 12.73%. Given Madrigal Pharmaceuticals' higher possible upside, analysts clearly believe Madrigal Pharmaceuticals is more favorable than United Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Madrigal Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.78
United Therapeutics
0 Sell rating(s)
2 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.85

Summary

United Therapeutics beats Madrigal Pharmaceuticals on 10 of the 17 factors compared between the two stocks.

How does Madrigal Pharmaceuticals compare to Incyte?

Incyte (NASDAQ:INCY) and Madrigal Pharmaceuticals (NASDAQ:MDGL) are both large-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their institutional ownership, earnings, risk, profitability, valuation, analyst recommendations, media sentiment and dividends.

Incyte has a beta of 0.79, suggesting that its stock price is 21% less volatile than the broader market. Comparatively, Madrigal Pharmaceuticals has a beta of -1.07, suggesting that its stock price is 207% less volatile than the broader market.

In the previous week, Incyte had 1 more articles in the media than Madrigal Pharmaceuticals. MarketBeat recorded 12 mentions for Incyte and 11 mentions for Madrigal Pharmaceuticals. Madrigal Pharmaceuticals' average media sentiment score of 0.68 beat Incyte's score of 0.44 indicating that Madrigal Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Incyte
5 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Neutral
Madrigal Pharmaceuticals
3 Very Positive mention(s)
3 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

97.0% of Incyte shares are owned by institutional investors. Comparatively, 98.5% of Madrigal Pharmaceuticals shares are owned by institutional investors. 16.2% of Incyte shares are owned by insiders. Comparatively, 17.6% of Madrigal Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Incyte currently has a consensus price target of $104.00, indicating a potential upside of 6.14%. Madrigal Pharmaceuticals has a consensus price target of $687.00, indicating a potential upside of 40.74%. Given Madrigal Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Madrigal Pharmaceuticals is more favorable than Incyte.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Incyte
1 Sell rating(s)
12 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.36
Madrigal Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.78

Incyte has higher revenue and earnings than Madrigal Pharmaceuticals. Madrigal Pharmaceuticals is trading at a lower price-to-earnings ratio than Incyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Incyte$5.14B3.81$1.29B$7.0813.84
Madrigal Pharmaceuticals$958.40M11.75-$288.28M-$12.80N/A

Incyte has a net margin of 26.71% compared to Madrigal Pharmaceuticals' net margin of -27.32%. Incyte's return on equity of 26.66% beat Madrigal Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Incyte26.71% 26.66% 19.77%
Madrigal Pharmaceuticals -27.32%-50.15%-25.44%

Summary

Incyte beats Madrigal Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Madrigal Pharmaceuticals compare to Neurocrine Biosciences?

Neurocrine Biosciences (NASDAQ:NBIX) and Madrigal Pharmaceuticals (NASDAQ:MDGL) are both large-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their dividends, earnings, profitability, institutional ownership, media sentiment, analyst recommendations, valuation and risk.

Neurocrine Biosciences has a beta of 0.4, indicating that its stock price is 60% less volatile than the broader market. Comparatively, Madrigal Pharmaceuticals has a beta of -1.07, indicating that its stock price is 207% less volatile than the broader market.

Neurocrine Biosciences has higher revenue and earnings than Madrigal Pharmaceuticals. Madrigal Pharmaceuticals is trading at a lower price-to-earnings ratio than Neurocrine Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Neurocrine Biosciences$2.86B5.80$478.60M$6.4925.44
Madrigal Pharmaceuticals$958.40M11.75-$288.28M-$12.80N/A

Neurocrine Biosciences presently has a consensus price target of $187.52, indicating a potential upside of 13.58%. Madrigal Pharmaceuticals has a consensus price target of $687.00, indicating a potential upside of 40.74%. Given Madrigal Pharmaceuticals' higher possible upside, analysts plainly believe Madrigal Pharmaceuticals is more favorable than Neurocrine Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Neurocrine Biosciences
0 Sell rating(s)
5 Hold rating(s)
17 Buy rating(s)
1 Strong Buy rating(s)
2.83
Madrigal Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.78

92.6% of Neurocrine Biosciences shares are held by institutional investors. Comparatively, 98.5% of Madrigal Pharmaceuticals shares are held by institutional investors. 4.6% of Neurocrine Biosciences shares are held by company insiders. Comparatively, 17.6% of Madrigal Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Neurocrine Biosciences has a net margin of 21.55% compared to Madrigal Pharmaceuticals' net margin of -27.32%. Neurocrine Biosciences' return on equity of 19.79% beat Madrigal Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Neurocrine Biosciences21.55% 19.79% 13.82%
Madrigal Pharmaceuticals -27.32%-50.15%-25.44%

In the previous week, Neurocrine Biosciences had 6 more articles in the media than Madrigal Pharmaceuticals. MarketBeat recorded 17 mentions for Neurocrine Biosciences and 11 mentions for Madrigal Pharmaceuticals. Madrigal Pharmaceuticals' average media sentiment score of 0.68 beat Neurocrine Biosciences' score of 0.29 indicating that Madrigal Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Neurocrine Biosciences
6 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Madrigal Pharmaceuticals
3 Very Positive mention(s)
3 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Neurocrine Biosciences beats Madrigal Pharmaceuticals on 11 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding MDGL and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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MDGL vs. The Competition

MetricMadrigal PharmaceuticalsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$10.44B$2.93B$6.47B$12.54B
Dividend YieldN/A1.68%2.69%5.22%
P/E Ratio-38.1417.6922.3924.18
Price / Sales11.75302.27520.79112.26
Price / CashN/A55.7241.3457.13
Price / Book18.393.859.846.72
Net Income-$288.28M$75.85M$3.57B$337.19M
7 Day Performance-7.49%-1.67%-1.16%0.48%
1 Month Performance-4.98%22.18%3.85%5.07%
1 Year Performance71.64%21.83%27.40%34.25%

Madrigal Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
MDGL
Madrigal Pharmaceuticals
2.79 of 5 stars
$488.15
+7.8%
$687.00
+40.7%
+66.1%$10.44B$958.40MN/A90
ALNY
Alnylam Pharmaceuticals
4.4161 of 5 stars
$295.63
-2.1%
$463.13
+56.7%
-6.5%$40.32B$3.71B80.772,770
BIIB
Biogen
3.0384 of 5 stars
$192.23
-1.9%
$215.81
+12.3%
+44.0%$28.94B$9.89B20.637,500
UTHR
United Therapeutics
4.1953 of 5 stars
$544.62
-2.2%
$619.42
+13.7%
+65.9%$23.64B$3.17B20.101,400
INCY
Incyte
4.2099 of 5 stars
$95.59
-1.2%
$104.00
+8.8%
+41.2%$19.33B$5.14B13.502,844

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This page (NASDAQ:MDGL) was last updated on 6/3/2026 by MarketBeat.com Staff.
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