| 07/09/2026 3:26 PM | Amylyx Pharmaceuticals (1658551) Subject Mazzariello Gina (1913765) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 06/08/2026 3:00 PM | Amylyx Pharmaceuticals (1658551) Issuer FONTEYNE PAUL R. (1727550) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/08/2026 3:00 PM | Amylyx Pharmaceuticals (1658551) Issuer MILNE GEORGE M JR (1179552) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/08/2026 3:00 PM | Amylyx Pharmaceuticals (1658551) Issuer Quimi Daphne (1543031) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/08/2026 3:00 PM | Amylyx Pharmaceuticals (1658551) Issuer Firestone Karen (1969821) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/08/2026 3:00 PM | Amylyx Pharmaceuticals (1658551) Issuer Zeiher Bernhardt G (1971421) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/04/2026 3:06 PM | Amylyx Pharmaceuticals (1658551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 05/07/2026 6:02 AM | Amylyx Pharmaceuticals (1658551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 05/07/2026 6:04 AM | Amylyx Pharmaceuticals (1658551) Filer | Form 10-Q General form for quarterly reports under Section 13 or 15(d) | |
| 04/23/2026 6:01 AM | Amylyx Pharmaceuticals (1658551) Filer | Form DEF 14A | |
| 04/23/2026 6:02 AM | Amylyx Pharmaceuticals (1658551) Filer | Form DEFA14A | |
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| 04/23/2026 6:03 AM | Amylyx Pharmaceuticals (1658551) Filer | Form ARS | |
| 03/26/2026 2:41 PM | Amylyx Pharmaceuticals (1658551) Subject VANGUARD GROUP INC (102909) Filed by | Form SCHEDULE 13G/A | |
| 03/24/2026 6:11 AM | Amylyx Pharmaceuticals (1658551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 03/09/2026 3:00 PM | Amylyx Pharmaceuticals (1658551) Issuer Bedrosian Camille L (1326969) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/09/2026 3:00 PM | Amylyx Pharmaceuticals (1658551) Issuer Klee Justin B. (1898314) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/09/2026 3:00 PM | Amylyx Pharmaceuticals (1658551) Issuer FRATES JAMES M (1235598) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/09/2026 3:00 PM | Amylyx Pharmaceuticals (1658551) Issuer Mazzariello Gina (1913765) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/09/2026 3:00 PM | Amylyx Pharmaceuticals (1658551) Issuer Cohen Joshua B (1898644) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/03/2026 7:01 AM | Amylyx Pharmaceuticals (1658551) Filer | Form S-3ASR | |
| 03/03/2026 6:02 AM | Amylyx Pharmaceuticals (1658551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 03/03/2026 6:10 AM | Amylyx Pharmaceuticals (1658551) Filer | Form 10-K Annual report pursuant to Section 13 or 15(d) | |
| 03/02/2026 3:30 PM | Amylyx Pharmaceuticals (1658551) Subject Cohen Joshua B (1898644) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 03/02/2026 3:30 PM | Amylyx Pharmaceuticals (1658551) Subject Mazzariello Gina (1913765) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 03/02/2026 3:30 PM | Amylyx Pharmaceuticals (1658551) Subject FRATES JAMES M (1235598) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 03/02/2026 3:30 PM | Amylyx Pharmaceuticals (1658551) Subject Bedrosian Camille L (1326969) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 03/02/2026 3:30 PM | Amylyx Pharmaceuticals (1658551) Subject Klee Justin B. (1898314) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 02/12/2026 8:09 AM | Adage Capital Management, L.P. (1535978) Filed by Amylyx Pharmaceuticals (1658551) Subject | Form SCHEDULE 13G/A | |
| 02/05/2026 12:16 PM | Amylyx Pharmaceuticals (1658551) Subject FMR LLC (315066) Filed by | Form SCHEDULE 13G/A | |
| 02/04/2026 3:05 PM | Amylyx Pharmaceuticals (1658551) Issuer Klee Justin B. (1898314) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/04/2026 3:05 PM | Amylyx Pharmaceuticals (1658551) Issuer Mazzariello Gina (1913765) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/04/2026 3:05 PM | Amylyx Pharmaceuticals (1658551) Issuer Cohen Joshua B (1898644) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/04/2026 3:05 PM | Amylyx Pharmaceuticals (1658551) Issuer FRATES JAMES M (1235598) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/02/2026 3:10 PM | Amylyx Pharmaceuticals (1658551) Subject FRATES JAMES M (1235598) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 02/02/2026 3:10 PM | Amylyx Pharmaceuticals (1658551) Subject Klee Justin B. (1898314) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 02/02/2026 3:10 PM | Amylyx Pharmaceuticals (1658551) Subject Cohen Joshua B (1898644) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 02/02/2026 3:10 PM | Amylyx Pharmaceuticals (1658551) Subject Mazzariello Gina (1913765) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 01/20/2026 8:46 PM | Amylyx Pharmaceuticals (1658551) Issuer Klee Justin B. (1898314) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 01/20/2026 8:46 PM | Amylyx Pharmaceuticals (1658551) Issuer Cohen Joshua B (1898644) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 01/15/2026 3:14 PM | Amylyx Pharmaceuticals (1658551) Subject Klee Justin B. (1898314) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 01/15/2026 3:17 PM | Amylyx Pharmaceuticals (1658551) Subject Cohen Joshua B (1898644) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
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| 01/14/2026 3:08 PM | Amylyx Pharmaceuticals (1658551) Issuer MILNE GEORGE M JR (1179552) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 01/08/2026 3:05 PM | Amylyx Pharmaceuticals (1658551) Issuer Cohen Joshua B (1898644) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 01/08/2026 3:05 PM | Amylyx Pharmaceuticals (1658551) Issuer FRATES JAMES M (1235598) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 01/08/2026 6:03 AM | Amylyx Pharmaceuticals (1658551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 01/06/2026 3:04 PM | Amylyx Pharmaceuticals (1658551) Subject Cohen Joshua B (1898644) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 01/06/2026 3:05 PM | Amylyx Pharmaceuticals (1658551) Subject Klee Justin B. (1898314) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 01/06/2026 3:05 PM | Amylyx Pharmaceuticals (1658551) Subject FRATES JAMES M (1235598) Reporting | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 12/23/2025 7:48 PM | Amylyx Pharmaceuticals (1658551) Issuer Firestone Karen (1969821) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 11/17/2025 4:39 PM | Amylyx Pharmaceuticals (1658551) Subject Commodore Capital LP (1831942) Filed by | Form SCHEDULE 13G | |
| 11/13/2025 8:05 AM | Adage Capital Management, L.P. (1535978) Filed by Amylyx Pharmaceuticals (1658551) Subject | Form SCHEDULE 13G/A | |
| 11/06/2025 6:03 AM | Amylyx Pharmaceuticals (1658551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 11/06/2025 6:11 AM | Amylyx Pharmaceuticals (1658551) Filer | Form 10-Q General form for quarterly reports under Section 13 or 15(d) | |
| 10/30/2025 1:37 PM | Amylyx Pharmaceuticals (1658551) Subject VANGUARD GROUP INC (102909) Filed by | Form SCHEDULE 13G/A | |
| 10/07/2025 2:49 PM | Amylyx Pharmaceuticals (1658551) Subject FMR LLC (315066) Filed by | Form SCHEDULE 13G | |
| 09/10/2025 3:55 PM | Amylyx Pharmaceuticals (1658551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 09/10/2025 3:44 PM | Amylyx Pharmaceuticals (1658551) Filer | Form 424B5 | |
| 09/09/2025 4:24 PM | Amylyx Pharmaceuticals (1658551) Filer | Form 424B5 | |
| 08/27/2025 6:05 AM | Amylyx Pharmaceuticals (1658551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 08/12/2025 8:07 AM | Adage Capital Management, L.P. (1535978) Filed by Amylyx Pharmaceuticals (1658551) Subject | Form SCHEDULE 13G/A | |
| 08/07/2025 6:03 AM | Amylyx Pharmaceuticals (1658551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 08/07/2025 6:15 AM | Amylyx Pharmaceuticals (1658551) Filer | Form 10-Q General form for quarterly reports under Section 13 or 15(d) | |
| 07/29/2025 10:21 AM | Amylyx Pharmaceuticals (1658551) Subject VANGUARD GROUP INC (102909) Filed by | Form SCHEDULE 13G | |
| 07/17/2025 6:44 PM | Amylyx Pharmaceuticals (1658551) Subject BlackRock, Inc. (2012383) Filed by | Form SCHEDULE 13G | |