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Amylyx Pharmaceuticals (AMLX) 10K Form and Latest SEC Filings 2026

Amylyx Pharmaceuticals logo
$38.66 -1.00 (-2.52%)
As of 08/21/2026 04:00 PM Eastern

Latest Amylyx Pharmaceuticals SEC Filings & Recent Activity

Amylyx Pharmaceuticals (NASDAQ:AMLX) has submitted 267+ documents to the U.S. Securities and Exchange Commission (SEC) since 2018. For investors, these filings are the primary source of verified financial data — covering everything from annual revenue and debt levels in the 10-K, to material business events in 8-K current reports, to insider buying and selling activity in Form 4 disclosures. Key figures from these filings, including revenue, earnings, and cash flow, are summarized in Amylyx Pharmaceuticals's financial statements. The most recent filing was a Form 4 submitted on August 20, 2026.

Form 4
Amylyx Pharmaceuticals, Inc. Reports Ownership Change on Aug. 20, 2026

Form 4 filings disclose changes in stock ownership by company insiders, including purchases, sales, grants, and option exercises.

View insider ownership

8-K
Amylyx Pharmaceuticals Files Current Report on Aug. 20, 2026

An 8-K is filed when a material corporate event occurs, such as an acquisition, leadership change, or financial update.

View filing

10-Q
Amylyx Pharmaceuticals Files Quarterly Report on Aug. 6, 2026

The 10-Q contains Amylyx Pharmaceuticals's unaudited quarterly financial statements, revenue, earnings updates, and cash flow changes between annual reports.

View earnings history

Amylyx Pharmaceuticals SEC Filing History

Browse Amylyx Pharmaceuticals' complete SEC filing history using the filters below. Filter by form type - 10-K, 10-Q, 8-K, Form 4, and more - or set a custom date range to find a filing.

DateFilerForm TypeView
08/20/2026 8:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
Cohen Joshua B (1898644) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
08/20/2026 8:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
Bedrosian Camille L (1326969) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
08/20/2026 8:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
Mazzariello Gina (1913765) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
08/20/2026 8:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
Klee Justin B. (1898314) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
08/20/2026 8:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
FRATES JAMES M (1235598) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
08/20/2026 4:27 PM
Amylyx Pharmaceuticals (1658551) Filer
Form 424B5
08/20/2026 4:28 PM
Amylyx Pharmaceuticals (1658551) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
08/18/2026 4:17 PM
Amylyx Pharmaceuticals (1658551) Filer
Form 424B5
08/18/2026 8:03 AM
Amylyx Pharmaceuticals (1658551) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
08/18/2026 6:09 AM
Amylyx Pharmaceuticals (1658551) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
08/06/2026 6:02 AM
Amylyx Pharmaceuticals (1658551) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
08/06/2026 6:04 AM
Amylyx Pharmaceuticals (1658551) Filer
Form 10-Q
General form for quarterly reports under Section 13 or 15(d)  
07/13/2026 3:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
Mazzariello Gina (1913765) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
07/09/2026 3:26 PM
Amylyx Pharmaceuticals (1658551) Subject
Mazzariello Gina (1913765) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
06/08/2026 3:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
FONTEYNE PAUL R. (1727550) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
06/08/2026 3:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
MILNE GEORGE M JR (1179552) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
06/08/2026 3:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
Quimi Daphne (1543031) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
06/08/2026 3:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
Firestone Karen (1969821) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
06/08/2026 3:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
Zeiher Bernhardt G (1971421) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
06/04/2026 3:06 PM
Amylyx Pharmaceuticals (1658551) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
05/07/2026 6:02 AM
Amylyx Pharmaceuticals (1658551) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
05/07/2026 6:04 AM
Amylyx Pharmaceuticals (1658551) Filer
Form 10-Q
General form for quarterly reports under Section 13 or 15(d)  
04/23/2026 6:01 AM
Amylyx Pharmaceuticals (1658551) Filer
Form DEF 14A
04/23/2026 6:02 AM
Amylyx Pharmaceuticals (1658551) Filer
Form DEFA14A
04/23/2026 6:03 AM
Amylyx Pharmaceuticals (1658551) Filer
Form ARS
03/26/2026 2:41 PM
Amylyx Pharmaceuticals (1658551) Subject
VANGUARD GROUP INC (102909) Filed by
Form SCHEDULE 13G/A
03/24/2026 6:11 AM
Amylyx Pharmaceuticals (1658551) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
03/09/2026 3:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
Bedrosian Camille L (1326969) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
03/09/2026 3:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
Klee Justin B. (1898314) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
03/09/2026 3:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
FRATES JAMES M (1235598) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
03/09/2026 3:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
Mazzariello Gina (1913765) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
03/09/2026 3:00 PM
Amylyx Pharmaceuticals (1658551) Issuer
Cohen Joshua B (1898644) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
03/03/2026 7:01 AM
Amylyx Pharmaceuticals (1658551) Filer
Form S-3ASR
03/03/2026 6:02 AM
Amylyx Pharmaceuticals (1658551) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
03/03/2026 6:10 AM
Amylyx Pharmaceuticals (1658551) Filer
Form 10-K
Annual report pursuant to Section 13 or 15(d)  
03/02/2026 3:30 PM
Amylyx Pharmaceuticals (1658551) Subject
Cohen Joshua B (1898644) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
03/02/2026 3:30 PM
Amylyx Pharmaceuticals (1658551) Subject
Mazzariello Gina (1913765) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
03/02/2026 3:30 PM
Amylyx Pharmaceuticals (1658551) Subject
FRATES JAMES M (1235598) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
03/02/2026 3:30 PM
Amylyx Pharmaceuticals (1658551) Subject
Bedrosian Camille L (1326969) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
03/02/2026 3:30 PM
Amylyx Pharmaceuticals (1658551) Subject
Klee Justin B. (1898314) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
02/12/2026 8:09 AM
Adage Capital Management, L.P. (1535978) Filed by
Amylyx Pharmaceuticals (1658551) Subject
Form SCHEDULE 13G/A
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02/05/2026 12:16 PM
Amylyx Pharmaceuticals (1658551) Subject
FMR LLC (315066) Filed by
Form SCHEDULE 13G/A
02/04/2026 3:05 PM
Amylyx Pharmaceuticals (1658551) Issuer
Klee Justin B. (1898314) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
02/04/2026 3:05 PM
Amylyx Pharmaceuticals (1658551) Issuer
Mazzariello Gina (1913765) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
02/04/2026 3:05 PM
Amylyx Pharmaceuticals (1658551) Issuer
Cohen Joshua B (1898644) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
02/04/2026 3:05 PM
Amylyx Pharmaceuticals (1658551) Issuer
FRATES JAMES M (1235598) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
02/02/2026 3:10 PM
Amylyx Pharmaceuticals (1658551) Subject
FRATES JAMES M (1235598) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
02/02/2026 3:10 PM
Amylyx Pharmaceuticals (1658551) Subject
Klee Justin B. (1898314) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
02/02/2026 3:10 PM
Amylyx Pharmaceuticals (1658551) Subject
Cohen Joshua B (1898644) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
02/02/2026 3:10 PM
Amylyx Pharmaceuticals (1658551) Subject
Mazzariello Gina (1913765) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
01/20/2026 8:46 PM
Amylyx Pharmaceuticals (1658551) Issuer
Klee Justin B. (1898314) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
01/20/2026 8:46 PM
Amylyx Pharmaceuticals (1658551) Issuer
Cohen Joshua B (1898644) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
01/15/2026 3:14 PM
Amylyx Pharmaceuticals (1658551) Subject
Klee Justin B. (1898314) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
01/15/2026 3:17 PM
Amylyx Pharmaceuticals (1658551) Subject
Cohen Joshua B (1898644) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
01/14/2026 3:08 PM
Amylyx Pharmaceuticals (1658551) Issuer
MILNE GEORGE M JR (1179552) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
01/08/2026 3:05 PM
Amylyx Pharmaceuticals (1658551) Issuer
Cohen Joshua B (1898644) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
01/08/2026 3:05 PM
Amylyx Pharmaceuticals (1658551) Issuer
FRATES JAMES M (1235598) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
01/08/2026 6:03 AM
Amylyx Pharmaceuticals (1658551) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
01/06/2026 3:04 PM
Amylyx Pharmaceuticals (1658551) Subject
Cohen Joshua B (1898644) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
01/06/2026 3:05 PM
Amylyx Pharmaceuticals (1658551) Subject
Klee Justin B. (1898314) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
01/06/2026 3:05 PM
Amylyx Pharmaceuticals (1658551) Subject
FRATES JAMES M (1235598) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
12/23/2025 7:48 PM
Amylyx Pharmaceuticals (1658551) Issuer
Firestone Karen (1969821) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
11/17/2025 4:39 PM
Amylyx Pharmaceuticals (1658551) Subject
Commodore Capital LP (1831942) Filed by
Form SCHEDULE 13G
11/13/2025 8:05 AM
Adage Capital Management, L.P. (1535978) Filed by
Amylyx Pharmaceuticals (1658551) Subject
Form SCHEDULE 13G/A
11/06/2025 6:03 AM
Amylyx Pharmaceuticals (1658551) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
11/06/2025 6:11 AM
Amylyx Pharmaceuticals (1658551) Filer
Form 10-Q
General form for quarterly reports under Section 13 or 15(d)  
10/30/2025 1:37 PM
Amylyx Pharmaceuticals (1658551) Subject
VANGUARD GROUP INC (102909) Filed by
Form SCHEDULE 13G/A
10/07/2025 2:49 PM
Amylyx Pharmaceuticals (1658551) Subject
FMR LLC (315066) Filed by
Form SCHEDULE 13G
09/10/2025 3:55 PM
Amylyx Pharmaceuticals (1658551) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
09/10/2025 3:44 PM
Amylyx Pharmaceuticals (1658551) Filer
Form 424B5
09/09/2025 4:24 PM
Amylyx Pharmaceuticals (1658551) Filer
Form 424B5
08/27/2025 6:05 AM
Amylyx Pharmaceuticals (1658551) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
(Data available from 1/1/2016 forward)

Amylyx Pharmaceuticals SEC Filings - Frequently Asked Questions

Amylyx Pharmaceuticals (AMLX) has submitted 267+ filings to the SEC since 2018. You can browse the complete history or filter by form type using the tools above.

Amylyx Pharmaceuticals's fiscal year ends on December 31. The company typically files its 10-K annual report by the end of February, covering the prior fiscal year's financial results. Key financial data from these reports is available on Amylyx Pharmaceuticals's financial statements page.

The most recent filing was a Form 4 submitted on August 20, 2026. This was an insider ownership change filed by 4 - Amylyx Pharmaceuticals, Inc. (0001658551) (Issuer).

SEC Filing Types: 10-K, 10-Q, 8-K and More

SEC filings are legally required disclosures that public companies submit to the U.S. Securities and Exchange Commission. Unlike press releases or earnings call transcripts, these documents are filed under legal obligation — meaning the financial data they contain is audited, standardized, and subject to penalties if materially false. For investors, that makes SEC filings the most reliable primary source available for evaluating a company's true financial position.

Yes. All SEC filings are publicly available through the SEC's EDGAR database and on financial research platforms like MarketBeat. Companies are required by law to make these disclosures accessible to all investors — meaning retail investors have access to the same source documents as institutional analysts.

A 10-K is an annual report containing audited financial statements and a full review of the company's business — it is the most comprehensive filing a company makes each year. A 10-Q is a shorter, unaudited quarterly update filed three times per year between annual reports. Investors typically use the 10-K for deep fundamental analysis and the 10-Q to track whether the company is on pace with its guidance mid-year.

The most important filing for fundamental investors. Filed once per year, the 10-K contains audited financial statements, revenue and earnings trends, debt obligations, risk factors, and management's own assessment of the business. Reading the risk factors section and comparing year-over-year financials can reveal issues that don't show up in analyst summaries.

An unaudited financial update filed three times per year (the 10-K covers Q4). Investors use 10-Qs to track whether guidance is on pace, monitor changes in cash flow or inventory, and catch any mid-year shifts in business conditions before they become headline news.

Filed within four business days of a material event — earnings releases, merger announcements, executive departures, or major asset sales. Because 8-Ks are filed before media coverage catches up, they are often the fastest way to get unfiltered information directly from the company on market-moving events.

Filed within two business days whenever an executive or director buys or sells company stock. Insider purchases — especially large or clustered buys — are often interpreted as a signal of management confidence. Insider selling is more ambiguous but worth monitoring for patterns, particularly around lock-up expirations or ahead of major announcements.


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This page (NASDAQ:AMLX) was last updated on 8/22/2026 by MarketBeat.com Staff.
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