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Vaxcyte (PCVX) Competitors

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$61.16 0.00 (0.00%)
As of 09/4/2026 04:00 PM Eastern

PCVX vs. BIIB, ALNY, INSM, BNTX, and INCY

Should you buy Vaxcyte stock or one of its competitors? Vaxcyte's main competitors and comparable companies include Biogen (BIIB), Alnylam Pharmaceuticals (ALNY), Insmed (INSM), BioNTech (BNTX), and Incyte (INCY). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Vaxcyte compare to Biogen?

Vaxcyte (NASDAQ:PCVX) and Biogen (NASDAQ:BIIB) are both healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their analyst recommendations, dividends, media sentiment, institutional ownership, earnings, profitability, valuation and risk.

96.8% of Vaxcyte shares are held by institutional investors. Comparatively, 87.9% of Biogen shares are held by institutional investors. 3.3% of Vaxcyte shares are held by insiders. Comparatively, 0.3% of Biogen shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Biogen has a net margin of 8.32% compared to Vaxcyte's net margin of 0.00%. Biogen's return on equity of 11.18% beat Vaxcyte's return on equity.

Company Net Margins Return on Equity Return on Assets
VaxcyteN/A -37.56% -33.62%
Biogen 8.32%11.18%6.88%

Vaxcyte has a beta of 1.22, meaning that its stock price is 22% more volatile than the broader market. Comparatively, Biogen has a beta of 0.17, meaning that its stock price is 83% less volatile than the broader market.

Vaxcyte presently has a consensus price target of $86.00, suggesting a potential upside of 40.61%. Biogen has a consensus price target of $228.50, suggesting a potential upside of 3.47%. Given Vaxcyte's higher possible upside, equities analysts clearly believe Vaxcyte is more favorable than Biogen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vaxcyte
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.50
Biogen
1 Sell rating(s)
13 Hold rating(s)
18 Buy rating(s)
1 Strong Buy rating(s)
2.58

Biogen has higher revenue and earnings than Vaxcyte. Vaxcyte is trading at a lower price-to-earnings ratio than Biogen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
VaxcyteN/AN/A-$766.63M-$7.63N/A
Biogen$9.89B3.30$1.29B$5.6539.08

In the previous week, Biogen had 15 more articles in the media than Vaxcyte. MarketBeat recorded 29 mentions for Biogen and 14 mentions for Vaxcyte. Vaxcyte's average media sentiment score of 1.12 beat Biogen's score of 1.05 indicating that Vaxcyte is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vaxcyte
9 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Biogen
17 Very Positive mention(s)
4 Positive mention(s)
7 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Biogen beats Vaxcyte on 11 of the 16 factors compared between the two stocks.

How does Vaxcyte compare to Alnylam Pharmaceuticals?

Vaxcyte (NASDAQ:PCVX) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their dividends, analyst recommendations, earnings, media sentiment, risk, institutional ownership, valuation and profitability.

96.8% of Vaxcyte shares are held by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. 3.3% of Vaxcyte shares are held by insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Vaxcyte has a beta of 1.22, meaning that its share price is 22% more volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.31, meaning that its share price is 69% less volatile than the broader market.

In the previous week, Vaxcyte and Vaxcyte both had 14 articles in the media. Vaxcyte's average media sentiment score of 1.12 beat Alnylam Pharmaceuticals' score of 0.91 indicating that Vaxcyte is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vaxcyte
9 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
5 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Alnylam Pharmaceuticals has higher revenue and earnings than Vaxcyte. Vaxcyte is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
VaxcyteN/AN/A-$766.63M-$7.63N/A
Alnylam Pharmaceuticals$3.71B9.59$313.75M$5.3849.46

Alnylam Pharmaceuticals has a net margin of 15.26% compared to Vaxcyte's net margin of 0.00%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Vaxcyte's return on equity.

Company Net Margins Return on Equity Return on Assets
VaxcyteN/A -37.56% -33.62%
Alnylam Pharmaceuticals 15.26%84.93%14.30%

Vaxcyte presently has a consensus price target of $86.00, indicating a potential upside of 40.61%. Alnylam Pharmaceuticals has a consensus price target of $386.14, indicating a potential upside of 45.10%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Alnylam Pharmaceuticals is more favorable than Vaxcyte.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vaxcyte
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.50
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.88

Summary

Alnylam Pharmaceuticals beats Vaxcyte on 11 of the 15 factors compared between the two stocks.

How does Vaxcyte compare to Insmed?

Insmed (NASDAQ:INSM) and Vaxcyte (NASDAQ:PCVX) are both healthcare companies, but which is the better business? We will compare the two businesses based on the strength of their earnings, valuation, media sentiment, dividends, profitability, analyst recommendations, institutional ownership and risk.

Insmed presently has a consensus target price of $205.52, indicating a potential upside of 62.74%. Vaxcyte has a consensus target price of $86.00, indicating a potential upside of 40.61%. Given Insmed's stronger consensus rating and higher probable upside, analysts clearly believe Insmed is more favorable than Vaxcyte.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Insmed
1 Sell rating(s)
0 Hold rating(s)
22 Buy rating(s)
2 Strong Buy rating(s)
3.00
Vaxcyte
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.50

Vaxcyte has a net margin of 0.00% compared to Insmed's net margin of -76.94%. Vaxcyte's return on equity of -37.56% beat Insmed's return on equity.

Company Net Margins Return on Equity Return on Assets
Insmed-76.94% -123.94% -44.30%
Vaxcyte N/A -37.56%-33.62%

96.8% of Vaxcyte shares are held by institutional investors. 2.1% of Insmed shares are held by insiders. Comparatively, 3.3% of Vaxcyte shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Vaxcyte has lower revenue, but higher earnings than Insmed. Insmed is trading at a lower price-to-earnings ratio than Vaxcyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Insmed$606.42M45.48-$1.28B-$4.11N/A
VaxcyteN/AN/A-$766.63M-$7.63N/A

In the previous week, Vaxcyte had 3 more articles in the media than Insmed. MarketBeat recorded 14 mentions for Vaxcyte and 11 mentions for Insmed. Vaxcyte's average media sentiment score of 1.12 beat Insmed's score of 0.98 indicating that Vaxcyte is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Insmed
7 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Vaxcyte
9 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Insmed has a beta of 0.82, suggesting that its share price is 18% less volatile than the broader market. Comparatively, Vaxcyte has a beta of 1.22, suggesting that its share price is 22% more volatile than the broader market.

Summary

Vaxcyte beats Insmed on 10 of the 16 factors compared between the two stocks.

How does Vaxcyte compare to BioNTech?

BioNTech (NASDAQ:BNTX) and Vaxcyte (NASDAQ:PCVX) are both healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their earnings, dividends, profitability, analyst recommendations, valuation, risk, institutional ownership and media sentiment.

15.5% of BioNTech shares are owned by institutional investors. Comparatively, 96.8% of Vaxcyte shares are owned by institutional investors. 19.2% of BioNTech shares are owned by company insiders. Comparatively, 3.3% of Vaxcyte shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Vaxcyte has a net margin of 0.00% compared to BioNTech's net margin of -63.54%. BioNTech's return on equity of -6.86% beat Vaxcyte's return on equity.

Company Net Margins Return on Equity Return on Assets
BioNTech-63.54% -6.86% -6.00%
Vaxcyte N/A -37.56%-33.62%

BioNTech currently has a consensus price target of $127.44, indicating a potential upside of 22.82%. Vaxcyte has a consensus price target of $86.00, indicating a potential upside of 40.61%. Given Vaxcyte's higher possible upside, analysts plainly believe Vaxcyte is more favorable than BioNTech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioNTech
1 Sell rating(s)
4 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.74
Vaxcyte
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.50

In the previous week, Vaxcyte had 12 more articles in the media than BioNTech. MarketBeat recorded 14 mentions for Vaxcyte and 2 mentions for BioNTech. Vaxcyte's average media sentiment score of 1.12 beat BioNTech's score of 0.09 indicating that Vaxcyte is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
BioNTech
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Vaxcyte
9 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

BioNTech has a beta of 1.29, suggesting that its share price is 29% more volatile than the broader market. Comparatively, Vaxcyte has a beta of 1.22, suggesting that its share price is 22% more volatile than the broader market.

Vaxcyte has lower revenue, but higher earnings than BioNTech. BioNTech is trading at a lower price-to-earnings ratio than Vaxcyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BioNTech$3.25B8.08-$1.29B-$7.83N/A
VaxcyteN/AN/A-$766.63M-$7.63N/A

Summary

BioNTech and Vaxcyte tied by winning 8 of the 16 factors compared between the two stocks.

How does Vaxcyte compare to Incyte?

Vaxcyte (NASDAQ:PCVX) and Incyte (NASDAQ:INCY) are both healthcare companies, but which is the better business? We will compare the two businesses based on the strength of their institutional ownership, earnings, risk, profitability, analyst recommendations, valuation, dividends and media sentiment.

96.8% of Vaxcyte shares are owned by institutional investors. Comparatively, 97.0% of Incyte shares are owned by institutional investors. 3.3% of Vaxcyte shares are owned by company insiders. Comparatively, 16.2% of Incyte shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Incyte has higher revenue and earnings than Vaxcyte. Vaxcyte is trading at a lower price-to-earnings ratio than Incyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
VaxcyteN/AN/A-$766.63M-$7.63N/A
Incyte$5.14B5.00$1.29B$7.8516.15

Incyte has a net margin of 27.71% compared to Vaxcyte's net margin of 0.00%. Incyte's return on equity of 29.93% beat Vaxcyte's return on equity.

Company Net Margins Return on Equity Return on Assets
VaxcyteN/A -37.56% -33.62%
Incyte 27.71%29.93%22.88%

Vaxcyte currently has a consensus target price of $86.00, indicating a potential upside of 40.61%. Incyte has a consensus target price of $124.05, indicating a potential downside of 2.13%. Given Vaxcyte's higher possible upside, research analysts clearly believe Vaxcyte is more favorable than Incyte.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vaxcyte
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.50
Incyte
0 Sell rating(s)
12 Hold rating(s)
11 Buy rating(s)
1 Strong Buy rating(s)
2.54

Vaxcyte has a beta of 1.22, indicating that its share price is 22% more volatile than the broader market. Comparatively, Incyte has a beta of 0.77, indicating that its share price is 23% less volatile than the broader market.

In the previous week, Vaxcyte had 1 more articles in the media than Incyte. MarketBeat recorded 14 mentions for Vaxcyte and 13 mentions for Incyte. Incyte's average media sentiment score of 1.28 beat Vaxcyte's score of 1.12 indicating that Incyte is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vaxcyte
9 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Incyte
11 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Incyte beats Vaxcyte on 13 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PCVX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PCVX vs. The Competition

MetricVaxcyteBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$9.10B$4.01B$7.25B$12.91B
Dividend YieldN/A3.60%2.54%9.13%
P/E Ratio-8.0212.65273.2725.43
Price / SalesN/A1,344.31624.5595.06
Price / CashN/A45.0028.9235.62
Price / Book2.9816.3911.016.39
Net Income-$766.63M-$22.85M$3.49B$358.69M
7 Day Performance0.69%1.43%1.63%0.22%
1 Month Performance5.32%6.00%4.42%-0.10%
1 Year Performance85.22%49.38%24.21%14.04%

Vaxcyte Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PCVX
Vaxcyte
2.3805 of 5 stars
$61.16
flat
$86.00
+40.6%
+85.2%$9.10BN/AN/A160
BIIB
Biogen
3.5004 of 5 stars
$216.65
-0.8%
$227.79
+5.1%
+57.0%$32.28B$10.03B38.357,500
ALNY
Alnylam Pharmaceuticals
4.6184 of 5 stars
$240.69
+1.5%
$386.14
+60.4%
-41.1%$31.73B$4.80B44.742,770
INSM
Insmed
3.7287 of 5 stars
$121.82
+2.8%
$205.52
+68.7%
-13.0%$25.89B$606.42MN/A1,664
BNTX
BioNTech
3.0027 of 5 stars
$101.61
-0.5%
$127.44
+25.4%
-7.7%$25.81B$3.25BN/A7,807

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This page (NASDAQ:PCVX) was last updated on 9/7/2026 by MarketBeat.com Staff.
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