AnaptysBio (ANAB) News Today $31.34 -0.63 (-1.97%) Closing price 10/2/2025 04:00 PM EasternExtended Trading$30.88 -0.47 (-1.48%) As of 08:33 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Headlines Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Why Is AnaptysBio Down Today?Toggle Visibility of Why Is AnaptysBio Down Today?AnaptysBio, Inc. (NASDAQ:ANAB) shares moved today amid a flurry of analyst rating changes and earnings-forecast revisions. Positive Sentiment: Analyst upgrade lifts ANAB nearly 9%. AnaptysBio Trading Up 8.9% on Analyst Upgrade Positive Sentiment: Leerink Partnrs raised Q4 2025 EPS to $1.04 from ($0.67), pointing to stronger late-year results. Positive Sentiment: Leerink Partnrs narrowed FY 2025 loss estimate to ($1.69) from ($3.97), cutting expected annual losses. Positive Sentiment: Leerink Partnrs improved FY 2028 outlook to ($1.87) from ($2.14) and FY 2029 to ($0.82) from ($0.92), signaling incremental progress toward profitability. Positive Sentiment: HC Wainwright lifted Q4 2025 EPS to ($1.62) from ($1.66), and boosted longer-term forecasts—FY 2026 to ($6.35) from ($8.15), FY 2028 to ($3.94) from ($9.83) and FY 2029 to ($1.88) from ($7.84)—while maintaining a Buy rating and $59 target. Neutral Sentiment: Guggenheim reiterated its Buy rating on ANAB without changing its outlook. Guggenheim Sticks to Their Buy Rating Negative Sentiment: Leerink Partnrs cut Q3 2025 EPS to ($0.85) from ($0.84), and trimmed FY 2027 and FY 2026 forecasts to ($3.01) from ($2.66) and to ($2.98) from ($1.18), respectively, indicating softer near-term profitability. Leerink Partnrs Decreases Earnings Estimates Negative Sentiment: HC Wainwright lowered Q3 2025 EPS to ($1.59) from ($1.51) and trimmed FY 2025 to ($5.82) from ($5.78), dampening short-term earnings visibility. Negative Sentiment: A “Time to Sell?” report followed a 5.9% share-price drop, underscoring investor caution ahead of upcoming data. ANAB Stock Price Down 5.9% - Time to Sell? Posted 1h agoAI Generated. May Contain Errors. ANAB Latest News All Sources Trusted Sources MarketBeat Barchart Benzinga Bloomberg GlobeNewswire GuruFocus MarketWatch Motley Fool NASDAQ PR Newswire Reuters Seeking Alpha TalkMarkets The Street TipRanks The Wall Street Journal Wall Street Zen Yahoo Finance Source Sentiment refers to the positivity or negativity of each headline according to our language processing algorithm. Sentiment All Sentiments Very Positive Positive Neutral Negative Very Negative Most Recent October 2025 September 2025 August 2025 July 2025 June 2025 May 2025 April 2025 March 2025 February 2025 January 2025 December 2024 November 2024 October 2024 September 2024 August 2024 July 2024 June 2024 May 2024 April 2024 March 2024 February 2024 January 2024 December 2023 November 2023 October 2023 September 2023 August 2023 July 2023 June 2023 May 2023 April 2023 March 2023 February 2023 January 2023 December 2022 November 2022 Time Period HighMark Wealth Management LLC Raises Stock Position in AnaptysBio, Inc. $ANAB2 hours ago | marketbeat.comLeerink Partnrs Decreases Earnings Estimates for AnaptysBio2 hours ago | marketbeat.comAnaptysBio (NASDAQ:ANAB) Trading Up 8.9% on Analyst UpgradeOctober 3 at 2:25 AM | americanbankingnews.comGuggenheim Sticks to Their Buy Rating for AnaptysBio (ANAB)October 2 at 4:37 PM | theglobeandmail.comAnaptysBio (NASDAQ:ANAB) Stock Price Down 5.9% - Time to Sell?October 2 at 3:32 PM | marketbeat.comHC Wainwright Analysts Cut Earnings Estimates for AnaptysBioOctober 2 at 7:31 AM | marketbeat.comAnaptysBio (NASDAQ:ANAB) Shares Up 8.9% on Analyst UpgradeOctober 1 at 1:14 PM | marketbeat.comWedbush Reiterates AnaptysBio (ANAB) Outperform RecommendationOctober 1 at 10:33 AM | msn.comAnaptysBio (NASDAQ:ANAB) Stock Price Expected to Rise, HC Wainwright Analyst SaysOctober 1 at 2:43 AM | americanbankingnews.comHC Wainwright & Co. Maintains AnaptysBio (ANAB) Buy RecommendationSeptember 30 at 2:51 PM | msn.comAnaptysBio Stock Gets A Price Target Hike After Announcing Plan To Separate Royalty, Biopharma Businesses – Check Out The New LevelSeptember 30 at 2:51 PM | msn.comAnaptysBio (NASDAQ:ANAB) Shares Gap Up Following Analyst UpgradeSeptember 30 at 10:33 AM | marketbeat.comAnaptysBio (NASDAQ:ANAB) Price Target Raised to $59.00 at HC WainwrightSeptember 30 at 8:26 AM | marketbeat.comWedbush Reiterates "Outperform" Rating for AnaptysBio (NASDAQ:ANAB)September 30 at 8:26 AM | marketbeat.comAnaptysBio, Inc. - Special CallSeptember 29, 2025 | seekingalpha.comAnaptysBio, Inc. (ANAB) (ANAB) Strategic Separation To Maximize Shareholder Value Presentation - SlideshowSeptember 29, 2025 | seekingalpha.comAnaptysBio, Inc. (ANAB) Discusses On Strategic Separation To Maximize Shareholder Value (Transcript)September 29, 2025 | seekingalpha.comAnaptysBio splits operations into two companiesSeptember 29, 2025 | msn.comAnaptys to Provide Overview of ANB033, a CD122 antagonist, at Virtual Investor Event on Tuesday, Oct. 14September 29, 2025 | globenewswire.comAnaptys Announces Intent to Separate Biopharma Operations from Substantial Royalty Assets by Year-end 2026September 29, 2025 | globenewswire.comAssenagon Asset Management S.A. Sells 225,526 Shares of AnaptysBio, Inc. $ANABSeptember 29, 2025 | marketbeat.comAnaptysBio jumps after Englander’s Millennium takes stakeSeptember 25, 2025 | msn.comAnaptysBio (NASDAQ:ANAB) Trading Up 9.9% - Still a Buy?September 24, 2025 | marketbeat.comVoya Investment Management LLC Purchases Shares of 96,972 AnaptysBio, Inc. $ANABSeptember 22, 2025 | marketbeat.comAnaptysBio (NASDAQ:ANAB) Receives Outperform Rating from WedbushSeptember 17, 2025 | marketbeat.comGoldman Sachs Group Inc. Sells 138,529 Shares of AnaptysBio, Inc. $ANABSeptember 17, 2025 | marketbeat.comAnaptysBio (NASDAQ:ANAB) Stock Price Down 4.3% - Here's What HappenedSeptember 16, 2025 | marketbeat.comAnaptysBio falls after data abstract on Lilly’s peresolimabSeptember 16, 2025 | msn.comReaction to peresolimab update ‘seems excessive,’ says TD CowenSeptember 16, 2025 | msn.comAnaptysBio, Inc. (NASDAQ:ANAB) Given Consensus Rating of "Moderate Buy" by BrokeragesSeptember 15, 2025 | marketbeat.comAnaptysBio, Inc. $ANAB Shares Bought by Woodline Partners LPSeptember 13, 2025 | marketbeat.com116,623 Shares in AnaptysBio, Inc. $ANAB Purchased by Exome Asset Management LLCSeptember 11, 2025 | marketbeat.comGranahan Investment Management LLC Boosts Stock Holdings in AnaptysBio, Inc. $ANABSeptember 8, 2025 | marketbeat.comPDT Partners LLC Takes $828,000 Position in AnaptysBio, Inc. $ANABSeptember 6, 2025 | marketbeat.comTrexquant Investment LP Boosts Stake in AnaptysBio, Inc. $ANABSeptember 6, 2025 | marketbeat.comAnaptysBio (NASDAQ:ANAB) Trading 5.1% Higher - Should You Buy?September 5, 2025 | marketbeat.comRafferty Asset Management LLC Cuts Stake in AnaptysBio, Inc. $ANABSeptember 5, 2025 | marketbeat.com683 Capital Management LLC Makes New $3.64 Million Investment in AnaptysBio, Inc. $ANABSeptember 4, 2025 | marketbeat.comFirst Light Asset Management LLC Raises Stock Holdings in AnaptysBio, Inc. $ANABSeptember 4, 2025 | marketbeat.comAnaptysBio, Inc. $ANAB Shares Purchased by Palo Alto Investors LPSeptember 4, 2025 | marketbeat.comNuveen LLC Makes New Investment in AnaptysBio, Inc. $ANABSeptember 3, 2025 | marketbeat.comAnaptysBio, Inc. $ANAB Shares Sold by Charles Schwab Investment Management Inc.September 1, 2025 | marketbeat.comVanguard Group Inc. Sells 326,415 Shares of AnaptysBio, Inc. $ANABAugust 30, 2025 | marketbeat.comCresset Asset Management LLC Purchases New Stake in AnaptysBio, Inc. $ANABAugust 28, 2025 | marketbeat.comAnaptys Announces Participation in September Investor ConferencesAugust 27, 2025 | globenewswire.comFox Run Management L.L.C. Makes New Investment in AnaptysBio, Inc. $ANABAugust 20, 2025 | marketbeat.comAnaptysBio, Inc. (NASDAQ:ANAB) Given Average Recommendation of "Moderate Buy" by BrokeragesAugust 20, 2025 | marketbeat.comAnaptysBio (NASDAQ:ANAB) Stock Price Expected to Rise, UBS Group Analyst SaysAugust 13, 2025 | marketbeat.comAnaptysBio price target raised to $20 from $18 at UBSAugust 13, 2025 | msn.comFederated Hermes Inc. Has $154,000 Holdings in AnaptysBio, Inc. (NASDAQ:ANAB)August 12, 2025 | marketbeat.com Get AnaptysBio News Delivered to You Automatically Sign up to receive the latest news and ratings for ANAB and its competitors with MarketBeat's FREE daily newsletter. 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Our company news sentiment scores track the average news sentiment of articles about each company over the most recent 7 days in order to identify companies that are receiving positive press. ANAB News Sentiment▼0.430.53▲Average Medical News Sentiment ANAB News Coverage Learn about the media coverage comparison. We track news headlines from hundreds of news outlets and tag them by company. This chart compares the number of articles about this company in the last seven days compared with the average number of articles about this company on a typical week. ANAB Articles This Week▼296▲ANAB Articles Average Week Get the Latest News and Ratings for ANAB and Related Stocks Enter your email address to receive the latest news and analysts' ratings for AnaptysBio and its competitors. 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