Bicycle Therapeutics (BCYC) Institutional Ownership $4.55 +0.10 (+2.25%) Closing price 05/22/2026 04:00 PM EasternExtended Trading$4.54 -0.01 (-0.22%) As of 05/22/2026 04:41 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Bicycle Therapeutics (NASDAQ:BCYC)CurrentInstitutional OwnershipPercentage86.15%Number ofInstitutional Buyers(last 12 months)57TotalInstitutional Inflows(last 12 months)$55.07MNumber ofInstitutional Sellers(last 12 months)21TotalInstitutional Outflows(last 12 months)$20.53M Get BCYC Insider Trade Alerts Want to know when executives and insiders are buying or selling Bicycle Therapeutics stock? Sign up for InsiderTrades.com's daily newsletter to get the latest insider transactions delivered to your inbox daily. 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Skip Chart & View Institutional Buying and Selling Data BCYC Institutional Buying and Selling by Quarter Bicycle Therapeutics Major Shareholders & Ownership History ExportReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails5/19/2026 Flax Pond Capital LLC176,136$817K0.7%+1.4%0.253% 5/18/2026 ADAR1 Capital Management LLC71,298$331K0.0%N/A0.102% 5/18/2026 Royal Bank of Canada14,470$67K0.0%+35.5%0.021% 5/18/2026 Eversept Partners LP190,715$885K0.0%+6.6%0.274% 5/15/2026 Rangeley Capital LLC232,260$1.08M1.0%+76.0%0.333% 5/14/2026 Renaissance Technologies LLC979,300$4.54M0.0%+72.8%1.405% 5/14/2026 Siren L.L.C.1,560,882$7.24M0.2%-22.5%2.239% 5/14/2026 Sei Investments Co.52,784$245K0.0%+7.6%0.076% 5/4/2026 Principal Financial Group Inc.1,174,625$5.45M0.0%+2.3%1.685% 4/29/2026 R Squared Ltd21,057$98K0.1%N/A0.030% Get the Latest News and Ratings for BCYC and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Bicycle Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 3/9/2026 Flax Pond Capital LLC173,633$1.23M0.9%N/A0.250% 2/19/2026 Invesco Ltd.10,092$71K0.0%N/A0.015% 2/18/2026 State of Tennessee Department of Treasury61,153$433K0.0%+36.4%0.088% 2/18/2026 XTX Topco Ltd47,674$338K0.0%+309.3%0.069% 2/18/2026 Virtus Investment Advisers LLC35,709$253K0.1%+172.7%0.051% 2/18/2026 Quadrature Capital Ltd46,728$331K0.0%+67.5%0.067% 2/18/2026 Millennium Management LLC326,626$2.31M0.0%-69.0%0.471% 2/18/2026 Moore Capital Management LP275,000$1.95M0.0%+120.0%0.396% 2/18/2026 Man Group plc42,860$303K0.0%+4.8%0.062% 2/18/2026 Engineers Gate Manager LP24,047$170K0.0%+79.2%0.035% 2/18/2026 Eversept Partners LP178,915$1.27M0.1%-8.0%0.258% 2/18/2026 Armistice Capital LLC3,236,000$22.91M0.3%+8.7%4.665% 2/17/2026 Jump Financial LLC31,000$219K0.0%+44.7%0.045% 2/17/2026 Price T Rowe Associates Inc. MD1,171,787$8.30M0.0%-15.4%1.689% 2/17/2026 Monimus Capital Management LP93,840$664K0.4%+10.1%0.135% 2/17/2026 Fcpm Iii Services B.V.3,468,430$24.56M3.3%+0.5%5.000% 2/17/2026 Royal Bank of Canada10,682$76K0.0%-16.1%0.015% 2/13/2026 Marshall Wace LLP38,795$275K0.0%N/A0.056% 2/13/2026 The Manufacturers Life Insurance Company 127,863$869K0.0%-9.0%0.184% 2/13/2026 Schroder Investment Management Group584,770$3.98M0.0%N/A0.843% 2/13/2026 Birchview Capital LP462,700$3.28M1.9%+200.5%0.667% 2/13/2026 State Street Corp70,178$497K0.0%-5.7%0.101% 2/13/2026 Vontobel Holding Ltd.10,000$71K0.0%N/A0.014% 2/12/2026 Brooklyn Investment Group10,216$69K0.0%N/A0.015% 2/12/2026 GSK plc1,529,561$10.83M1.4%N/A2.205% 2/12/2026 Renaissance Technologies LLC566,600$4.01M0.0%+9.2%0.817% 2/12/2026 Marex Group plc78,406$555K0.0%N/A0.113% 2/12/2026 Alps Advisors Inc.40,995$290K0.0%+69.9%0.059% 2/11/2026 Fox Run Management L.L.C.19,771$140K0.0%N/A0.029% 2/11/2026 Westfield Capital Management Co. 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Click here now.2/10/2026 TD Asset Management Inc147,992$1.05M0.0%-16.9%0.213% 2/10/2026 Goldman Sachs Group Inc.24,732$175K0.0%N/A0.036% 2/9/2026 Geode Capital Management LLC25,129$178K0.0%-37.1%0.036% 2/9/2026 Clearstead Advisors LLC4,655$33K0.0%+234.2%0.007% 2/9/2026 Fideuram Intesa Sanpaolo Private Banking S.P.A.134,689$954K0.0%N/A0.194% 2/9/2026Jefferies Financial Group Inc.297,247$2.11M0.0%-26.0%0.428% 2/6/2026 Fideuram Intesa Sanpaolo Private Banking S.P.A.134,689$954K0.0%N/A0.194% 2/5/2026 Pinnacle Associates Ltd.190,480$1.35M0.0%-3.1%0.275% 2/2/2026 Pinnacle Wealth Management Advisory Group LLC10,000$71K0.0%N/A0.014% 1/14/2026 Woodstock Corp29,146$206K0.0%+21.8%0.042% 11/17/2025 Armistice Capital LLC2,978,000$23.05M0.3%+6.4%4.293% 11/17/2025 Palo Alto Investors LP221,071$1.71M0.3%-11.2%0.319% 11/17/2025 Long Focus Capital Management LLC1,418,695$10.98M0.4%+7.7%2.045% 11/17/2025 Millennium Management LLC1,054,746$8.16M0.0%-26.9%1.520% 11/17/2025 Moore Capital Management LP125,000$968K0.0%+66.7%0.180% 11/17/2025 Citadel Advisors LLC189,027$1.46M0.0%+20.3%0.272% 11/17/2025 Bank of America Corp DE591,535$4.58M0.0%-28.8%0.853% 11/17/2025 Ameriprise Financial Inc.14,972$116K0.0%+21.7%0.022% 11/14/2025 Man Group plc40,891$316K0.0%+42.6%0.059% 11/14/2025 Two Sigma Investments LP184,537$1.43M0.0%+228.4%0.266% 11/13/2025 Platinum Investment Management Ltd.184,603$1.43M0.1%-35.3%0.266% 11/13/2025 Tocqueville Asset Management L.P.12,300$95K0.0%-46.3%0.018% 11/13/2025 Sei Investments Co.49,056$380K0.0%+361.2%0.071% 11/13/2025 Legal & General Group Plc197,917$1.53M0.0%+13.2%0.286% 11/13/2025Jefferies Financial Group Inc.401,926$3.11M0.0%-12.8%0.580% 11/13/2025 Pinnacle Associates Ltd.196,618$1.52M0.0%+14.3%0.284% 11/13/2025 Dynamic Technology Lab Private Ltd27,959$216K0.0%-39.2%0.040% 11/12/2025 Handelsbanken Fonder AB150,000$1.16M0.0%-25.0%0.216% 11/12/2025 Westfield Capital Management Co. LP2,952,543$22.85M0.1%+6.2%4.260% 11/10/2025 TD Asset Management Inc178,092$1.38M0.0%-7.8%0.257% 11/7/2025 State of New Jersey Common Pension Fund D20,105$156K0.0%N/A0.029% 11/6/2025 Assetmark Inc.3,625$28K0.0%+74.9%0.005% 11/5/2025 Alps Advisors Inc.24,123$187K0.0%-6.3%0.035% 11/4/2025 Principal Financial Group Inc.1,148,402$8.89M0.0%+64.7%1.657% 10/31/2025 Vanguard Personalized Indexing Management LLC12,953$100K0.0%N/A0.019% 10/15/2025 Harbor Capital Advisors Inc.41,368$320K0.0%-70.2%0.060% 8/15/2025 State of Tennessee Department of Treasury14,382$100K0.0%N/A0.021% 8/15/2025 Soleus Capital Management L.P.100,000$695K0.0%N/A0.144% 8/15/2025 Monimus Capital Management LP85,224$592K0.4%N/A0.123% 8/15/2025 Rangeley Capital LLC75,000$521K0.6%N/A0.108% 8/15/2025 Moore Capital Management LP75,000$521K0.0%+50.0%0.108% 8/15/2025 Man Group plc28,675$199K0.0%N/A0.041% 8/15/2025 Engineers Gate Manager LP15,402$107K0.0%N/A0.022% 8/15/2025 Bank of America Corp DE830,634$5.77M0.0%+47.4%1.199% 8/15/2025 Ameriprise Financial Inc.12,304$86K0.0%N/A0.018% 8/14/2025 Paloma Partners Management Co39,250$273K0.0%N/A0.057% 8/14/2025 Jane Street Group LLC22,607$157K0.0%N/A0.033% 8/14/2025 Ausdal Financial Partners Inc.10,000$70K0.0%N/A0.014% 8/14/2025 Armistice Capital LLC2,800,000$19.46M0.3%+4.8%4.043% 8/14/2025 The Manufacturers Life Insurance Company 140,492$976K0.0%+1.6%0.203% Hey, it's Jon Najarian. 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(Ad)After being invited to the SpaceX launch headquarters in Cape Canaveral from one of Elon's top lobbyists… Hall of Fame Trader Jon Najarian now says EVERYONE is missing an even bigger story about the SpaceX IPO… That it's just the start of an Elon Musk $44 trillion "Superconvergence…" An event that could kick off as soon as June 12th.Click here now to watch hall of fame trader Jon Najarian's full prediction.8/14/2025 Sei Investments Co.10,637$74K0.0%N/A0.015% 8/14/2025 AXA S.A.280,152$1.95M0.0%-49.4%0.405% 8/13/2025 Jump Financial LLC16,740$116K0.0%N/A0.024% 8/13/2025 Virtus Investment Advisers LLC10,821$75K0.0%+32.6%0.016% 8/13/2025 Quadrature Capital Ltd17,738$123K0.0%N/A0.026% 8/12/2025Jefferies Financial Group Inc.461,100$3.21M0.0%+12.8%0.666% 8/12/2025 Legal & General Group Plc174,910$1.21M0.0%+28.9%0.253% 8/12/2025 Handelsbanken Fonder AB200,000$1.39M0.0%-7.4%0.289% 8/12/2025 Dynamic Technology Lab Private Ltd45,950$320K0.0%N/A0.066% 8/12/2025 Westfield Capital Management Co. LP2,780,491$19.32M0.1%+4.6%4.015% BCYC Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of BCYC shares? During the previous two years, 109 institutional investors and hedge funds held shares of Bicycle Therapeutics. The most heavily invested institutionals were Baker BROS. Advisors LP ($152.40M), Point72 Asset Management L.P. ($63.77M), First Light Asset Management LLC ($28.03M), Fcpm Iii Services B.V. ($24.56M), Armistice Capital LLC ($22.91M), Westfield Capital Management Co. LP ($21.35M), and Deep Track Capital LP ($17.87M).Learn more on Bicycle Therapeutics' institutional investors. What percentage of Bicycle Therapeutics' stock is owned by institutional investors? 86.15% of Bicycle Therapeutics' stock is owned by institutional investors. Learn more on BCYC's institutional investor holdings. Which institutional investors have been buying Bicycle Therapeutics' stock? Of the 92 institutional investors that purchased Bicycle Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Point72 Asset Management L.P. ($4.50M), Principal Financial Group Inc. ($1.59M), GSK plc ($1.53M), Baker BROS. Advisors LP ($1.49M), Long Focus Capital Management LLC ($1.40M), Armistice Capital LLC ($1.34M), and Fcpm Iii Services B.V. ($1.13M). How much institutional buying is happening at Bicycle Therapeutics? Institutional investors have bought a total of 7,923,218 shares in the last 24 months. This purchase volume represents approximately $55.07M in transactions. Which of Bicycle Therapeutics' major shareholders have been selling company stock? Of the 21 institutional investors that sold Bicycle Therapeutics' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Millennium Management LLC ($1.12M), Siren L.L.C. ($451.87K), AXA S.A. ($273.53K), Bank of America Corp DE ($239.10K), Price T Rowe Associates Inc. MD ($213.01K), Jefferies Financial Group Inc. ($163.85K), and Harbor Capital Advisors Inc. ($106.76K). How much institutional selling is happening at Bicycle Therapeutics? Institutional investors have sold a total of 2,967,708 shares in the last 24 months. This volume of shares sold represents approximately $20.53M in transactions. Related Companies Maplight Therapeutics Institutional Ownership Septerna Institutional Ownership Olema Pharmaceuticals Institutional Ownership DBV Technologies Institutional Ownership Harrow Institutional Ownership Jade Biosciences Institutional Ownership Collegium Pharmaceutical Institutional Ownership Xeris Biopharma Institutional Ownership Maravai LifeSciences Institutional Ownership CureVac Institutional Ownership This page (NASDAQ:BCYC) was last updated on 5/24/2026 by MarketBeat.com Staff. From Our PartnersHey, it's Jon Najarian. The SpaceX IPO is right around the corner. 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