BioLineRx Ltd. is a clinical-stage biopharmaceutical company focused on the development and commercialization of novel therapeutics for oncology, immunology and neuroscience indications. The company’s pipeline includes small molecules and peptides designed to address areas of high unmet medical need, with a primary emphasis on the treatment of various cancers and immune-related disorders. BioLineRx pursues a rigorous, science-driven approach, advancing candidates from preclinical research through Phase II and III clinical trials.
Among its lead programs is motixafortide (BL-8040), a selective CXCR4 antagonist being evaluated in combination regimens for acute myeloid leukemia and metastatic pancreatic cancer. Additional pipeline assets include BL-1020, a GABA-modulating agent for the treatment of schizophrenia, and other proprietary candidates targeting fibrosis, neuroinflammation and acute pain. These programs leverage targeted mechanisms of action to achieve improved efficacy and safety profiles compared with existing therapies.
Founded in 2003 and headquartered in Petah Tikva, Israel, BioLineRx has established collaborations with leading academic institutions and contract research organizations across North America, Europe and Asia. The company’s global footprint supports multi-center clinical trials, regulatory filings and strategic partnerships aimed at accelerating the development of its pipeline. Through licensing agreements and co-development arrangements, BioLineRx seeks to maximize the commercial potential of its candidates while managing development risk.
BioLineRx is guided by an experienced management team and board of directors with deep expertise in biotechnology, clinical development and corporate finance. The leadership team combines academic research credentials with industry experience, fostering a disciplined approach to program prioritization, regulatory strategy and investor relations. With a commitment to scientific excellence and patient-centric innovation, BioLineRx strives to bring new treatment options to market for challenging diseases.
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