Bio-Path Holdings, Inc. is a clinical-stage biopharmaceutical company focused on the development of novel RNA-based therapies for the treatment of cancer. Leveraging its proprietary nanoscale liposomal DNA/RNA delivery platform, Bio-Path designs molecules that target key cancer-promoting genes and pathways. Its lead programs include BP-1001, an antisense oligonucleotide targeting Grb2 for hematological malignancies, and BP-1002, which inhibits the BCL-2 gene to induce apoptosis in cancer cells. These targeted approaches aim to overcome limitations of conventional chemotherapy by improving drug delivery and reducing off-target effects.
The company’s pipeline is built around its Nano-sugar functionalized liposome delivery system, which enhances cellular uptake and stability of therapeutic oligonucleotides. Bio-Path has advanced multiple candidates into clinical trials for acute myeloid leukemia, myelodysplastic syndrome and solid tumors, including ongoing Phase 1/2 studies. Preclinical work on additional programs, such as BP-1003, explores complementary oncogenic pathways, positioning the company for potential expansion of its product portfolio.
Founded in 2004 and headquartered in Henderson, Nevada, Bio-Path conducts research and development activities at its laboratory facilities in Houston, Texas. The company collaborates with leading cancer centers and contract research organizations across North America and Europe to support its global clinical trial efforts. Its strategic partnerships and academic alliances provide access to advanced translational science and accelerate the path toward regulatory milestones.
Under the leadership of Chief Executive Officer Peter Yanchurov, Bio-Path is guided by a management team with extensive experience in oncology drug development, clinical operations and financing. The company’s board of directors includes industry veterans and scientific experts who oversee strategic decision-making and corporate governance. Bio-Path continues to seek capital and partnering opportunities to support its mission of delivering innovative RNA-based therapies to patients with high-need cancers.
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