Creative Medical Technology Holdings, Inc. (NASDAQ: CELZ) is a clinical‐stage biotechnology company focused on the development, manufacture and commercialization of exosome‐based therapies derived from human bone marrow mesenchymal stem cells. The company’s proprietary exosome platform is being investigated for applications in regenerative medicine, aesthetic dermatology, wound healing and anti‐inflammatory treatments. Creative Medical leverages cGMP manufacturing processes to produce sterile, cell‐free exosome formulations designed to support tissue repair and cellular rejuvenation.
The company’s lead product candidates include XoFlo, an exosome enrichment product intended for use in musculoskeletal and soft tissue injuries, and specialized formulations targeting skin rejuvenation and scar reduction. Creative Medical collaborates with research institutions and clinical sites to advance its pipeline through preclinical and clinical studies, seeking to validate safety and efficacy across multiple therapeutic areas. The firm also develops ancillary products for in‐office administration by healthcare professionals, emphasizing ease of use and regulatory compliance.
Headquartered in Scottsdale, Arizona, Creative Medical serves a network of medical clinics, plastic surgery centers and sports medicine practices across the United States, with growing distribution in select international markets. The company’s team combines expertise in stem cell biology, exosome science and regulatory affairs to support product advancement and market access. Creative Medical continues to explore strategic partnerships to expand its research capabilities and commercial footprint.
Since its inception, Creative Medical has pursued a mission to harness the regenerative potential of exosomes without the complexities of live cell therapies. Through ongoing research, process optimization and quality control, the company aims to deliver innovative treatment options that address unmet clinical needs in tissue repair and aesthetic enhancement. Management comprises experienced professionals in biotechnology development, quality assurance and regulatory strategy, guiding the company toward clinical milestones and commercial readiness.
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