Cognition Therapeutics (CGTX) Stock Price, News & Analysis

Company Overview

Cognition Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing disease-modifying therapies for neurodegenerative disorders, with an emphasis on Alzheimer’s disease. The company’s lead investigational candidate, CT1812, is an oral small molecule that antagonizes the sigma-2 receptor complex to protect synapses from amyloid-beta oligomer toxicity. By targeting a novel mechanism of action, Cognition Therapeutics aims to slow or reverse cognitive decline in patients living with Alzheimer’s disease.

CT1812 has successfully completed Phase 1 safety studies and preliminary Phase 2a trials, and is currently being evaluated in multiple Phase 2 clinical studies across North America and Europe in patients with mild-to-moderate Alzheimer’s disease. In addition to its lead program, the company is advancing a preclinical pipeline aimed at expanding its approach to other neurodegenerative conditions. To support its global development efforts, Cognition Therapeutics collaborates with academic centers, contract research organizations and specialized clinical sites.

Headquartered in Pittsburgh, Pennsylvania, Cognition Therapeutics conducts operations primarily in the United States, with ongoing clinical and regulatory activities in European markets. The company is led by co-founder and CEO Stephen M. Maccecchini, Ph.D., who oversees research, development and strategic partnerships. Cognition Therapeutics’ common stock is traded on the NASDAQ under the ticker symbol CGTX.

Key Stats

• Today's Range: $1.87 to $2.38
• 50-Day Range: $0.53 to $3.18
• 52-Week Range: $0.22 to $3.83
• Volume: 5.45 million shs
• Average Volume: 7.76 million shs
• Market Capitalization: $159.54 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $2.83
• Consensus Rating: Buy

Cognition Therapeutics Stock Analysis - MarketRank™

Cognition Therapeutics scored higher than 57% of companies evaluated by MarketBeat, and ranked 502nd out of 958 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 4.0 / 5
• Analyst Rating: Buy

Consensus Rating

Cognition Therapeutics has received a consensus rating of Buy. The company's average rating score is 3.25, and is based on 3 buy ratings, no hold ratings, and no sell ratings.

Upside Potential

Cognition Therapeutics has a consensus price target of $2.83, representing about 30.6% upside from its current price of $2.17.

Amount of Analyst Coverage

Cognition Therapeutics has only been the subject of 2 research reports in the past 90 days.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for Cognition Therapeutics are expected to grow in the coming year, from ($0.80) to ($0.67) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Cognition Therapeutics is -3.24, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Cognition Therapeutics is -3.24, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Cognition Therapeutics has a P/B Ratio of 7.00. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.

Short Interest

• Score: 2.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

15.60% of the float of Cognition Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Cognition Therapeutics has a short interest ratio ("days to cover") of 0.9, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Cognition Therapeutics has recently increased by 47.83%, indicating that investor sentiment is decreasing significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Cognition Therapeutics does not currently pay a dividend.

Dividend Growth

Cognition Therapeutics does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

15.60% of the float of Cognition Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Cognition Therapeutics has a short interest ratio ("days to cover") of 0.9, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Cognition Therapeutics has recently increased by 47.83%, indicating that investor sentiment is decreasing significantly.

News and Social Media

• Score: 3.1 / 5
• News Sentiment: 0.61

News Sentiment

Cognition Therapeutics has a news sentiment score of 0.61. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.93 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 6 news articles for Cognition Therapeutics this week, compared to 2 articles on an average week.

Search Interest

52 people have searched for CGTX on MarketBeat in the last 30 days. This is an increase of 68% compared to the previous 30 days.

MarketBeat Follows

10 people have added Cognition Therapeutics to their MarketBeat watchlist in the last 30 days. This is an increase of 67% compared to the previous 30 days.

Company Ownership

• Score: 1.7 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, Cognition Therapeutics insiders have not sold or bought any company stock.

Percentage Held by Insiders

14.40% of the stock of Cognition Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.

Percentage Held by Institutions

43.35% of the stock of Cognition Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

CGTX Stock Analysis - Frequently Asked Questions

How have CGTX shares performed this year?

Cognition Therapeutics' stock was trading at $0.7013 at the beginning of 2025. Since then, CGTX stock has increased by 209.4% and is now trading at $2.17.

How were Cognition Therapeutics' earnings last quarter?

Cognition Therapeutics, Inc. (NASDAQ:CGTX) posted its earnings results on Thursday, August, 7th. The company reported ($0.11) EPS for the quarter, topping the consensus estimate of ($0.12) by $0.01.

When did Cognition Therapeutics IPO?

Cognition Therapeutics (CGTX) raised $45 million in an initial public offering on Friday, October 8th 2021. The company issued 3,768,116 shares at $11.00-$13.00 per share.

How do I buy shares of Cognition Therapeutics?

Shares of CGTX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Cognition Therapeutics own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Cognition Therapeutics investors own include NVIDIA (NVDA), Broadcom (AVGO), Eli Lilly and Company (LLY), Meta Platforms (META), GE Aerospace (GE), Arista Networks (ANET) and Celestica (CLS).

Company Calendar

• Last Earnings: 8/07/2025
• Today: 9/12/2025
• Next Earnings (Estimated): 11/12/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:CGTX
• CIK: 1455365
• Web: www.cogrx.com
• Phone: 412-481-2210
• Fax: N/A
• Employees: 20
• Year Founded: N/A

Price Target and Rating

• Average Price Target for Cognition Therapeutics: $2.83
• High Price Target: $4.00
• Low Price Target: $1.50
• Potential Upside/Downside: +30.6%
• Consensus Rating: Buy
• Rating Score (0-4): 3.25
• Research Coverage: 4 Analysts

Profitability

• EPS (Trailing Twelve Months): ($0.67)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$33.97 million
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: -251.23%
• Return on Assets: -130.75%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 1.54
• Quick Ratio: 1.54

Sales & Book Value

• Annual Sales: N/A
• Price / Sales: N/A
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $0.31 per share
• Price / Book: 7.00

Miscellaneous

• Outstanding Shares: 73,520,000
• Free Float: 62,937,000
• Market Cap: $159.54 million
• Optionable: Not Optionable
• Beta: 1.33