NASDAQ:CUE Cue Biopharma (CUE) Stock Price, News & Analysis $35.51 -0.22 (-0.61%) As of 12:10 PM Eastern This is a fair market value price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Cue Biopharma Stock (NASDAQ:CUE) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Cue Biopharma alerts:Sign Up Key Stats Today's Range$34.01▼$36.9850-Day Range$12.45▼$764.6452-Week Range$4.97▼$41.42Volume95,524 shsAverage Volume531,561 shsMarket Capitalization$115.06 millionP/E RatioN/ADividend YieldN/APrice TargetN/AConsensus RatingSell Company Overview Cue Biopharma is a clinical‐stage biotechnology company focused on the development of next‐generation immunotherapies for cancer and infectious diseases. The company’s proprietary platform, known as Cytokine Release & Targeting (CRT), is designed to deliver cytokine payloads directly to antigen‐specific T cells in order to enhance immune responses within targeted tissues. This approach aims to improve the therapeutic index of cytokine treatments by limiting systemic exposure and potentiating localized immune activation. Founded in 2015 and headquartered in Cambridge, Massachusetts, Cue Biopharma has advanced multiple lead programs into early‐stage clinical studies. Its most advanced candidate, CUE-101, is an HLA‐peptide‐cytokine fusion designed to stimulate T cells specific to HPV16‐positive cancers. Additional programs—such as CUE-102 and CUE-301—seek to address solid tumors and viral infections by harnessing the same platform technology to selectively expand disease-relevant T cell populations. The company’s research and manufacturing activities are conducted primarily in the United States, with collaborations and partnerships aimed at accelerating clinical development. Under the leadership of President and CEO Darren Cline, Cue Biopharma has completed its initial public offering in 2021 and continues to build its research capabilities through strategic alliances with academic institutions and contract development organizations. The management team combines expertise in immunology, protein engineering and clinical development, positioning the company to advance its pipeline toward key clinical milestones. With its unique CRT platform, Cue Biopharma seeks to offer differentiated, antigen‐specific immunotherapies that may overcome limitations of current cytokine and cell‐based treatments.AI Generated. May Contain Errors. Read More Cue Biopharma Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks5th Percentile Overall ScoreCUE MarketRank™: Cue Biopharma scored higher than 5% of companies evaluated by MarketBeat, and ranked 842nd out of 860 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion0.7 / 5Analyst RatingSell Consensus RatingCue Biopharma has received a consensus rating of Sell. The company's average rating score is 1.00, and is based on no strong buy ratings, no buy ratings, no hold ratings, and 1 sell rating.Amount of Analyst CoverageCue Biopharma has only been the subject of 1 research reports in the past 90 days.Read more about Cue Biopharma's stock forecast and price target. Earnings and Valuation0.0 / 5Proj. Earnings GrowthN/A Price to Earnings Ratio vs. the MarketThe P/E ratio of Cue Biopharma is -3.58, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Cue Biopharma is -3.58, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioCue Biopharma has a P/B Ratio of 3.41. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities. Short InterestN/AShort Interest LevelN/A Short InterestThere is no current short interest data available for CUE. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldCue Biopharma does not currently pay a dividend.Dividend GrowthCue Biopharma does not have a long track record of dividend growth. News and Social Media3.4 / 5News Sentiment0.52 News SentimentCue Biopharma has a news sentiment score of 0.52. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This news sentiment score is similar to the average news sentiment of Medical companies.News Coverage This WeekMarketBeat has tracked 6 news articles for Cue Biopharma this week, compared to 2 articles on an average week.Search Interest64 people have searched for CUE on MarketBeat in the last 30 days. This is an increase of 814% compared to the previous 30 days.MarketBeat Follows4 people have added Cue Biopharma to their MarketBeat watchlist in the last 30 days. Company Ownership0.5 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Cue Biopharma insiders have not sold or bought any company stock.Percentage Held by Insiders1.82% of the stock of Cue Biopharma is held by insiders.Percentage Held by Institutions35.04% of the stock of Cue Biopharma is held by institutions.Read more about Cue Biopharma's insider trading history. Receive CUE Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Cue Biopharma and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. 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CUE Stock News HeadlinesCue Biopharma Grants Inducement Equity Awards to New Executive and EmployeesMay 7 at 7:31 PM | quiverquant.comQCue Biopharma Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)May 7 at 7:07 PM | globenewswire.comThe cat is out the bagAlmost 80,000 tech jobs vanished in the first three months of 2026. Meta cut 14,000 roles, Microsoft offered separation packages to 8,500 workers, and Oracle is reportedly eliminating up to 30,000 positions. Goldman Sachs estimates 12,400 Americans are being financially displaced every single day. Analyst Porter Stansberry says the real driver runs deeper than AI - and two Nobel Prize winners have issued the same warning. He calls it the Final Displacement, and he's releasing a full investigation with specific companies to buy and sell before the next wave hits.May 8 at 1:00 AM | Porter & Company (Ad)CUE stock jumps over 100% after hours — what’s driving the rally?May 1, 2026 | msn.comCue Biopharma Names Lin as CEO, Secures Exclusive License Agreement with Ascendant Health SciencesMay 1, 2026 | marketwatch.comCue Biopharma Announces $30 Million PIPE Financing Agreement to Advance Clinical PipelineApril 30, 2026 | quiverquant.comQCue Biopharma Announces $30 Million Private PlacementApril 30, 2026 | globenewswire.comCue Biopharma Expands Pipeline with Exclusive License from Ascendant Health Sciences Ltd. for Clinical-Stage Dual-Mechanism Anti-IgE AntibodyApril 30, 2026 | globenewswire.comSee More Headlines CUE Stock Analysis - Frequently Asked Questions How have CUE shares performed this year? Cue Biopharma's stock was trading at $274.86 at the beginning of the year. Since then, CUE stock has decreased by 87.1% and is now trading at $35.5110. How were Cue Biopharma's earnings last quarter? Cue Biopharma, Inc. (NASDAQ:CUE) issued its quarterly earnings data on Wednesday, November, 12th. The company reported ($63.00) EPS for the quarter, beating the consensus estimate of ($90.00) by $27.00. The firm earned $2.15 million during the quarter, compared to analysts' expectations of $2.29 million. Cue Biopharma had a negative trailing twelve-month return on equity of 165.19% and a negative net margin of 96.85%. When did Cue Biopharma's stock split? Shares of Cue Biopharma reverse split before market open on Thursday, April 23rd 2026.The 1-30 reverse split was announced on Wednesday, April 22nd 2026. The number of shares owned by shareholders was adjusted after the closing bell on Wednesday, April 22nd 2026. An investor that had 100 shares of stock prior to the reverse split would have 3 shares after the split. When did Cue Biopharma IPO? Cue Biopharma (CUE) raised $62 million in an IPO on Tuesday, January 2nd 2018. The company issued 8,820,710 shares at a price of $6.00-$8.00 per share. How do I buy shares of Cue Biopharma? Shares of CUE stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Cue Biopharma own? Based on aggregate information from My MarketBeat watchlists, some other companies that Cue Biopharma investors own include NVIDIA (NVDA), Tesla (TSLA), Advanced Micro Devices (AMD), Meta Platforms (META), JPMorgan Chase & Co. (JPM), Netflix (NFLX) and Company Calendar Last Earnings11/12/2025Today5/08/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (1w+) 1-Year History May 25 Aug 25 Nov 25 Feb 26 May 26 For the last 8 days, CUE's financial health has been in the Green zone, according to TradeSmith. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:CUE CIK1645460 Webwww.cuebiopharma.com Phone(617) 949-2680FaxN/AEmployees60Year Founded2015Profitability EPS (Trailing Twelve Months)($9.61) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$26.60 million Net Margins-96.85% Pretax Margin-95.03% Return on Equity-165.19% Return on Assets-77.77% Debt Debt-to-Equity RatioN/A Current Ratio2.74 Quick Ratio2.74 Sales & Book Value Annual Sales$27.47 million Price / Sales4.19 Cash FlowN/A Price / Cash FlowN/A Book Value$10.08 per share Price / Book3.52Miscellaneous Outstanding Shares3,240,000Free Float3,181,000Market Cap$115.06 million OptionableOptionable Beta2.37 Social Links Reduce the RiskMarket downturns give many investors pause, and for good reason. Wondering how to offset this risk? Click the link to learn more about using beta to protect your portfolio.Get This Free Report This page (NASDAQ:CUE) was last updated on 5/8/2026 by MarketBeat.com Staff. From Our PartnersYour book attachedYour Download Link (Expiring) If you still haven't downloaded the free Simple Options Trading For Beginners...Profits Run | SponsoredIran's New Leader Just Said Something That Should Terrify Every AmericanIran's Supreme Leader has declared the Strait of Hormuz closed as leverage against the U.S. - and with 40% of ...American Alternative | SponsoredOne executive order. 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