Precision BioSciences (DTIL) Stock Price, News & Analysis

Company Overview

Precision BioSciences, Inc., an advanced gene editing company, develops in vivo gene editing therapies for gene edits, including gene elimination, insertion, and excision in the United States. The company offers ARCUS, a genome editing platform to DNA genome insertion, deletion, and repair. It also provides PBGENE-HBV for the treatment of chronic hepatitis B virus (HBV) to eliminate covalently closed circular DNA with direct cuts and edits as well as to inactivate integrated HBV DNA with the goal of long-lasting reductions in hepatitis B surface antigen; PBGENE-PMM for the treatment of m.3243 associated primary mitochondrial myopathy (PMM) which is expected to submit an IND and/or CTA. In addition, it develops PBGENE-NVS for sickle cell disease/beta thalassemia for insertion; PBGENE-DMD (excision) for duchenne muscular dystrophy; PBGENE-LL2 (insertion), a liver directed target; PBGENE-LL3, a central nervous system directed target; and iECURE-OTC (insertion) for ornithine transcarbamylase deficiency. The company has license and collaboration agreement with Caribou Biosciences, Inc.; license agreement with TG Cell Therapy, Inc. to develop, manufacture, and commercialize azer-cel for autoimmune diseases and other indications outside of cancer; development and license agreement with Eli Lilly and Company for the research and development of potential in vivo therapies for genetic disorders; Cellectis S.A.; iECURE, Inc. to develop ARCUS-based gene-insertion therapies; Duke University; and Novartis Pharma AG to discover and develop in vivo gene editing products. Precision BioSciences, Inc. was incorporated in 2006 and is headquartered in Durham, North Carolina.

Key Stats

• Today's Range: $5.00 to $5.18
• 50-Day Range: $4.13 to $5.15
• 52-Week Range: $3.61 to $11.09
• Volume: 64,651 shs
• Average Volume: 322,044 shs
• Market Capitalization: $59.41 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $47.00
• Consensus Rating: Buy

Precision BioSciences Stock Analysis - MarketRank™

Precision BioSciences scored higher than 77% of companies evaluated by MarketBeat, and ranked 236th out of 929 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.5 / 5
• Analyst Rating: Buy

Consensus Rating

Precision BioSciences has received a consensus rating of Buy. The company's average rating score is 3.00, and is based on 2 buy ratings, no hold ratings, and no sell ratings.

Amount of Analyst Coverage

Precision BioSciences has received no research coverage in the past 90 days.

Earnings and Valuation

• Score: 1.3 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for Precision BioSciences are expected to grow in the coming year, from ($1.23) to ($1.05) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Precision BioSciences is -0.58, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Precision BioSciences is -0.58, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Precision BioSciences has a P/B Ratio of 0.74. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.

Short Interest

• Score: 1.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

14.75% of the float of Precision BioSciences has been sold short.

Short Interest Ratio / Days to Cover

Precision BioSciences has a short interest ratio ("days to cover") of 4.8.

Change versus previous month

Short interest in Precision BioSciences has recently increased by 17.59%, indicating that investor sentiment is decreasing significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Precision BioSciences does not currently pay a dividend.

Dividend Growth

Precision BioSciences does not have a long track record of dividend growth.

Sustainability and ESG

• Score: 4.6 / 5
• Environmental Score: -0.99

Percentage of Shares Shorted

14.75% of the float of Precision BioSciences has been sold short.

Short Interest Ratio / Days to Cover

Precision BioSciences has a short interest ratio ("days to cover") of 4.8.

Change versus previous month

Short interest in Precision BioSciences has recently increased by 17.59%, indicating that investor sentiment is decreasing significantly.

News and Social Media

• Score: 0.6 / 5
• News Sentiment: N/A

Search Interest

Only 6 people have searched for DTIL on MarketBeat in the last 30 days. This is a decrease of -45% compared to the previous 30 days.

MarketBeat Follows

2 people have added Precision BioSciences to their MarketBeat watchlist in the last 30 days.

Company Ownership

• Score: 1.7 / 5
• Insider Trading: Selling Shares

Insider Buying vs. Insider Selling

In the past three months, Precision BioSciences insiders have sold 807.12% more of their company's stock than they have bought. Specifically, they have bought $6,963.00 in company stock and sold $63,163.00 in company stock.

Percentage Held by Insiders

Only 4.50% of the stock of Precision BioSciences is held by insiders.

Percentage Held by Institutions

Only 37.99% of the stock of Precision BioSciences is held by institutions.

DTIL Stock Analysis - Frequently Asked Questions

How have DTIL shares performed this year?

Precision BioSciences' stock was trading at $3.81 at the beginning of 2025. Since then, DTIL stock has increased by 33.9% and is now trading at $5.10.

How were Precision BioSciences' earnings last quarter?

Precision BioSciences, Inc. (NASDAQ:DTIL) posted its earnings results on Thursday, August, 7th. The company reported ($2.13) earnings per share for the quarter, missing the consensus estimate of ($0.09) by $2.04. The company earned $0.02 million during the quarter, compared to the consensus estimate of $6.27 million. Precision BioSciences had a negative net margin of 6,205.79% and a negative trailing twelve-month return on equity of 176.47%.

When did Precision BioSciences' stock split?

Precision BioSciences's stock reverse split on Wednesday, February 14th 2024.The 1-30 reverse split was announced on Wednesday, February 14th 2024. The number of shares owned by shareholders was adjusted after the closing bell on Wednesday, February 14th 2024. An investor that had 100 shares of stock prior to the reverse split would have 3 shares after the split.

When did Precision BioSciences IPO?

Precision BioSciences (DTIL) raised $126 million in an initial public offering on Thursday, March 28th 2019. The company issued 7,900,000 shares at a price of $15.00-$17.00 per share. J.P. Morgan, Goldman Sachs, Jefferies and Barclays served as the underwriters for the IPO.

Who are Precision BioSciences' major shareholders?

Precision BioSciences' top institutional shareholders include Corient Private Wealth LLC (0.86%), Geode Capital Management LLC (0.70%) and Bridgeway Capital Management LLC (0.53%). Insiders that own company stock include J Jefferson Smith, John Alexander Kelly, Melinda Brown, Geno J Germano, Dario Scimeca and Alan List.
View institutional ownership trends.

How do I buy shares of Precision BioSciences?

Shares of DTIL stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Precision BioSciences own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Precision BioSciences investors own include Editas Medicine (EDIT), Luminar Technologies (LAZR), CRISPR Therapeutics (CRSP), Enovix (ENVX), Nokia (NOK) and Ginkgo Bioworks (DNA).

Company Calendar

• Last Earnings: 8/07/2025
• Today: 8/26/2025
• Next Earnings (Estimated): 11/03/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:DTIL
• CIK: 1357874
• Web: www.precisionbiosciences.com
• Phone: (919) 314-5512
• Fax: N/A
• Employees: 200
• Year Founded: N/A

Price Target and Rating

• Average Price Target for Precision BioSciences: $47.00
• High Price Target: $60.00
• Low Price Target: $34.00
• Potential Upside/Downside: +816.2%
• Consensus Rating: Buy
• Rating Score (0-4): 3.00
• Research Coverage: 2 Analysts

Profitability

• EPS (Trailing Twelve Months): ($8.81)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: $7.17 million
• Net Margins: -6,205.79%
• Pretax Margin: -6,205.79%
• Return on Equity: -176.47%
• Return on Assets: -69.05%

Debt

• Debt-to-Equity Ratio: 0.66
• Current Ratio: 5.18
• Quick Ratio: 5.18

Sales & Book Value

• Annual Sales: $1.26 million
• Price / Sales: 47.95
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $6.87 per share
• Price / Book: 0.75

Miscellaneous

• Outstanding Shares: 11,787,000
• Free Float: 11,316,000
• Market Cap: $60.47 million
• Optionable: No Data
• Beta: 1.52