Esperion Therapeutics (ESPR) Short Interest Ratio & Short Volume $3.10 -0.03 (-0.80%) As of 01:29 PM Eastern This is a fair market value price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Esperion Therapeutics Short Interest DataEsperion Therapeutics (ESPR) has a short interest of 24.80 million shares, representing 12.59% of the float (the number of shares available for trading by the public). This marks a 10.96% increase in short interest from the previous month. The short interest ratio (days to cover) is 4.6, indicating that it would take 4.6 days of the average trading volume of 5.16 million shares to cover all short positions.Current Short Interest24,800,000 sharesPrevious Short Interest22,350,000 sharesChange Vs. Previous Month+10.96%Dollar Volume Sold Short$68.94 millionShort Interest Ratio4.6 Days to CoverLast Record DateSeptember 15, 2025Outstanding Shares201,620,000 sharesFloat Size196,990,000 sharesShort Percent of Float12.59%Today's Trading Volume2,999,452 sharesAverage Trading Volume5,159,123 sharesToday's Volume Vs. Average58% Short Selling Esperion Therapeutics? Sign up to receive the latest short interest report for Esperion Therapeutics and its competitors with MarketBeat's FREE newsletter. Email Address Get Report View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. 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Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartESPR Short Interest Over TimeESPR Days to Cover Over TimeESPR Percentage of Float Shorted Over Time Esperion Therapeutics Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 9/15/202524,800,000 shares $68.94 million +11.0%12.6%4.6 $2.78 8/31/202522,350,000 shares $49.62 million -1.3%11.4%4.5 $2.22 8/15/202522,640,000 shares $46.41 million -2.1%11.5%4.9 $2.05 7/31/202523,130,000 shares $32.84 million +4.7%12.0%4.7 $1.42 7/15/202522,100,000 shares $24.97 million -8.0%11.4%4.5 $1.13 6/30/202524,030,000 shares $23.66 million -0.3%12.4%4.8 $0.98 6/15/202524,110,000 shares $28.21 million -8.5%12.4%4.7 $1.17 5/31/202526,340,000 shares $22.50 million -5.8%13.5%4.8 $0.85 5/15/202527,950,000 shares $21.72 million -6.4%14.4%5.2 $0.78 4/30/202529,860,000 shares $29.84 million -0.6%15.3%6.4 $1.00 Get the Latest News and Ratings for ESPR and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Esperion Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 4/15/202530,030,000 shares $29.90 million +7.2%15.4%6.6 $1.00 3/31/202528,020,000 shares $40.35 million -3.0%14.4%6.4 $1.44 3/15/202528,900,000 shares $43.35 million -0.8%14.9%6.8 $1.50 2/28/202529,140,000 shares $49.54 million +3.7%14.9%5.4 $1.70 2/15/202528,100,000 shares $52.27 million -10.1%14.4%5.1 $1.86 1/31/202531,240,000 shares $55.92 million -8.1%16.0%5 $1.79 1/15/202533,980,000 shares $75.10 million +5.0%17.4%5.6 $2.21 12/31/202432,350,000 shares $71.17 million +27.0%16.6%5.7 $2.20 12/15/202425,470,000 shares $57.31 million -16.5%13.1%4.6 $2.25 11/30/202430,490,000 shares $85.37 million -2.4%15.6%6.7 $2.80 11/15/202431,250,000 shares $66.25 million -6.6%16.0%8.2 $2.12 10/31/202433,460,000 shares $68.26 million -5.5%17.2%8.8 $2.04 10/15/202435,390,000 shares $75.38 million -5.6%18.2%9.7 $2.13 9/30/202437,470,000 shares $61.83 million -1.6%19.3%9.3 $1.65 9/15/202438,090,000 shares $72.75 million -5.8%19.6%6.9 $1.91 8/31/202440,440,000 shares $74.01 million -3.1%20.8%6.4 $1.83 8/15/202441,730,000 shares $82.21 million +9.4%21.5%6 $1.97 7/31/202438,140,000 shares $88.10 million -3.3%22.2%5.1 $2.31 7/15/202439,420,000 shares $98.55 million +67.4%25.5%4.8 $2.50 6/30/202423,550,000 shares $52.28 million -5.4%15.2%2.8 $2.22 6/15/202424,890,000 shares $74.42 million +13.7%16.1%3 $2.99 5/31/202421,890,000 shares $47.28 million -12.1%14.2%2.8 $2.16 5/15/202424,910,000 shares $57.29 million +25.4%16.1%3.4 $2.30 4/30/202419,870,000 shares $39.14 million +6.8%11.8%2.9 $1.97 4/15/202418,600,000 shares $35.99 million -6.6%11.0%3 $1.94 3/31/202419,920,000 shares $53.39 million +12.7%11.8%3 $2.68 3/15/202417,670,000 shares $36.58 million +4.3%10.5%2.8 $2.07 2/29/202416,950,000 shares $42.54 million -8.7%10.0%2.8 $2.51 2/15/202418,570,000 shares $49.40 million -7.5%11.0%3 $2.66 1/31/202420,070,000 shares $42.95 million -0.6%11.9%3.3 $2.14 1/15/202420,200,000 shares $61.00 million +1.4%17.9%3.7 $3.02 12/31/202319,920,000 shares $59.56 million +9.2%17.7%4.3 $2.99 12/15/202318,240,000 shares $33.20 million +2.8%16.2%4.3 $1.82 11/30/202317,740,000 shares $23.59 million -3.1%15.7%4.6 $1.33 11/15/202318,310,000 shares $21.06 million +0.5%16.2%4.7 $1.15 10/31/202318,220,000 shares $15.10 million -5.2%17.2%4.8 $0.83 10/15/202319,220,000 shares $15.95 million -3.0%18.1%5 $0.83 9/30/202319,810,000 shares $19.41 million +20.4%18.7%5.5 $0.98 9/15/202316,460,000 shares $23.37 million +8.4%15.5%4.7 $1.42 8/31/202315,180,000 shares $24.29 million +8.5%14.3%4.8 $1.60 8/15/202313,990,000 shares $22.94 million +4.3%13.2%5 $1.64 7/31/202313,410,000 shares $21.05 million +2.9%12.7%4.9 $1.57 7/15/202313,030,000 shares $18.76 million +4.2%13.9%5.4 $1.44 6/30/202312,510,000 shares $17.39 million -9.9%13.3%5.1 $1.39 6/15/202313,880,000 shares $19.02 million +3.8%14.8%5 $1.37 5/31/202313,370,000 shares $18.18 million -8.4%14.3%3.6 $1.36 5/15/202314,600,000 shares $24.82 million No Change15.6%3.5 $1.70 10/31/202214,030,000 shares $114.06 million +5.3%N/A11.6 $8.13 10/15/202213,330,000 shares $101.31 million +6.6%N/A11.5 $7.60 9/30/202212,500,000 shares $83.75 million -0.9%N/A12.1 $6.70 9/15/202212,610,000 shares $94.83 million -5.5%N/A12.6 $7.52 8/31/202213,350,000 shares $99.59 million +8.6%N/A13.9 $7.46 8/15/202212,290,000 shares $81.97 million -1.8%N/A13.7 $6.67 7/31/202212,520,000 shares $72.24 million +3.2%N/A12.9 $5.77 7/15/202212,130,000 shares $81.39 million +2.6%N/A11.8 $6.71 6/30/202211,820,000 shares $75.18 million +6.8%N/A10.2 $6.36 6/15/202211,070,000 shares $59.00 million -4.2%N/A9.1 $5.33 5/31/202211,560,000 shares $65.89 million +13.7%N/A8.7 $5.70 5/15/202210,170,000 shares $58.78 million +15.8%N/A7.3 $5.78 4/30/20228,780,000 shares $49.87 million +10.0%N/A6.4 $5.68 4/15/20227,980,000 shares $47.00 million +8.7%N/A6.3 $5.89 3/31/20227,340,000 shares $34.06 million +36.7%N/A0 $4.64 3/15/20225,370,000 shares $24.70 million +29.7%N/A4 $4.60 2/28/20224,140,000 shares $16.93 million +18.0%N/A2.7 $4.09 2/15/20223,510,000 shares $14.00 million +11.4%N/A1.6 $3.99 1/31/20223,150,000 shares $13.51 million -3.7%N/A1.4 $4.29 1/15/20223,270,000 shares $12.85 million -62.2%N/A1.5 $3.93 12/31/20218,650,000 shares $43.25 million +10.6%N/A3.9 $5.00 12/15/20217,820,000 shares $41.84 million -20.9%N/A3.8 $5.35 11/30/20219,880,000 shares $86.25 million +11.5%N/A5.2 $8.73 11/15/20218,860,000 shares $77.26 million -3.5%N/A8.1 $8.72 10/29/20219,180,000 shares $82.07 million +15.2%N/A9.5 $8.94 10/15/20217,970,000 shares $72.85 million +8.7%28.7%9.3 $9.14 9/30/20217,330,000 shares $88.33 million -10.0%26.4%9.7 $12.05 9/15/20218,140,000 shares $92.31 million +0.5%29.3%11.4 $11.34 8/31/20218,100,000 shares $105.46 million -7.1%29.2%14.1 $13.02 8/13/20218,720,000 shares $121.30 million -3.3%31.4%15.4 $13.91 7/30/20219,020,000 shares $138.82 million -5.1%32.5%14.5 $15.39 7/15/20219,500,000 shares $167.96 million +5.2%34.3%14.1 $17.68 6/30/20219,030,000 shares $190.98 million +0.9%32.6%13.7 $21.15 6/15/20218,950,000 shares $221.96 million -0.4%32.3%14.2 $24.80 5/28/20218,990,000 shares $178.99 million -1.5%32.4%13.8 $19.91 5/14/20219,130,000 shares $204.51 million -5.8%N/A13.4 $22.40 4/30/20219,690,000 shares $264.63 million -0.8%40.8%14.1 $27.31 4/15/20219,770,000 shares $265.26 million +3.3%N/A14 $27.15 3/31/20219,460,000 shares $259.58 million -3.1%N/A12.1 $27.44 3/15/20219,760,000 shares $296.12 million -3.5%N/A11.7 $30.34 2/26/202110,110,000 shares $279.84 million +5.9%N/A12.2 $27.68 2/12/20219,550,000 shares $293.57 million -5.8%35.5%11.7 $30.74 1/29/202110,140,000 shares $325.70 million -8.5%37.7%12.3 $32.12 1/15/202111,080,000 shares $296.39 million +2.8%N/A12.9 $26.75 12/31/202010,780,000 shares $303.46 million +6.5%N/A15.7 $28.15 12/15/202010,120,000 shares $299.35 million +3.5%44.0%15.5 $29.58 11/30/20209,780,000 shares $264.26 million +0.9%42.5%16 $27.02 11/15/20209,690,000 shares $278.01 million -3.7%42.1%15.2 $28.69 10/30/202010,060,000 shares $315.48 million -0.7%43.7%16.3 $31.36 10/15/202010,130,000 shares $342.19 million -9.1%N/A17.5 $33.78 ESPR Short Interest - Frequently Asked Questions What is Esperion Therapeutics' current short interest? Short interest is the volume of Esperion Therapeutics shares that have been sold short but have not yet been closed out or covered. As of September 15th, investors have sold 24,800,000 shares of ESPR short. 12.59% of Esperion Therapeutics' shares are currently sold short. Learn More on Esperion Therapeutics' current short interest. What is a good short interest ratio for Esperion Therapeutics? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. ESPR shares currently have a short interest ratio of 5.0. Learn More on Esperion Therapeutics's short interest ratio. Which institutional investors are shorting Esperion Therapeutics? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of Esperion Therapeutics: Group One Trading LLC, and Simplex Trading LLC. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. What is a good short interest percentage for Esperion Therapeutics? Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 12.59% of Esperion Therapeutics' floating shares are currently sold short. Is Esperion Therapeutics' short interest increasing or decreasing? Esperion Therapeutics saw a increase in short interest in September. As of September 15th, there was short interest totaling 24,800,000 shares, an increase of 11.0% from the previous total of 22,350,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. What is Esperion Therapeutics' float size? Esperion Therapeutics currently has issued a total of 201,620,000 shares. Some of Esperion Therapeutics' outstanding shares are available for trading, while others are subject to various restrictions. The public float, also referred to as floating shares or "the float", are shares that publicly owned, unrestricted and available to trade on the open market. Esperion Therapeutics currently has a public float of 196,990,000 shares. How does Esperion Therapeutics' short interest compare to its competitors? 12.59% of Esperion Therapeutics' shares are currently sold short. Here is how the short interest of companies in the industry of "pharmaceutical products" compare to Esperion Therapeutics: Denali Therapeutics Inc. (10.00%), Mesoblast Limited (2.01%), Adaptive Biotechnologies Corporation (6.13%), Tilray Brands, Inc. (14.04%), ANI Pharmaceuticals, Inc. (9.45%), Vera Therapeutics, Inc. (19.29%), Sarepta Therapeutics, Inc. (20.76%), Apogee Therapeutics Inc. (22.58%), Intellia Therapeutics, Inc. (31.80%), Harrow, Inc. (14.14%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: AppLovin Corporation ($8.81 billion), Canadian Natural Resources Limited ($5.82 billion), Reddit Inc. ($5.19 billion), Coinbase Global, Inc. ($4.52 billion), Robinhood Markets, Inc. ($4.30 billion), Charter Communications, Inc. ($3.75 billion), CoreWeave Inc. ($3.66 billion), Seagate Technology Holdings PLC ($3.57 billion), Live Nation Entertainment, Inc. ($3.33 billion), and Rocket Lab Corporation ($3.26 billion). View all of the most shorted stocks. What does it mean to sell short Esperion Therapeutics stock? Short selling ESPR is an investing strategy that aims to generate trading profit from Esperion Therapeutics as its price is falling. ESPR shares are trading down $0.18 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Esperion Therapeutics? A short squeeze for Esperion Therapeutics occurs when it has a large amount of short interest and its stock appreciates in price. This forces short sellers to cover their short interest positions by buying actual shares of ESPR, which in turn drives the price of the stock up even further. How often is Esperion Therapeutics' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including ESPR, twice per month. The most recent reporting period available is September, 15 2025. More Short Interest Resources from MarketBeat Related Companies Denali Therapeutics Short Squeeze Mesoblast Short Squeeze Adaptive Biotechnologies Short Squeeze Tilray Brands Short Squeeze ANI Pharmaceuticals Short Squeeze Vera Therapeutics Short Squeeze Sarepta Therapeutics Short Squeeze Apogee Therapeutics Short Squeeze Intellia Therapeutics Short Squeeze Harrow Short Squeeze Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:ESPR) was last updated on 10/7/2025 by MarketBeat.com Staff From Our PartnersMagnificent 7 being replaced by the “Hidden 7”?BULLISH: It's time to buy this 'hidden' AI stock An award-winning stock-rating system has turned BULLISH on...Chaikin Analytics | SponsoredU.S. Government Sparking Crypto RallyU.S. Puts GDP on the Blockchain Could this spark the next crypto supercycle? 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