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Esperion Therapeutics (ESPR) Competitors

Esperion Therapeutics logo
$3.18 0.00 (0.00%)
As of 07/13/2026

ESPR vs. ELVN, IDYA, MBX, IRON, and RARE

Should you buy Esperion Therapeutics stock or one of its competitors? MarketBeat compares Esperion Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Esperion Therapeutics include Enliven Therapeutics (ELVN), IDEAYA Biosciences (IDYA), MBX Biosciences (MBX), Disc Medicine (IRON), and Ultragenyx Pharmaceutical (RARE). These companies are all part of the "pharmaceutical products" industry.

How does Esperion Therapeutics compare to Enliven Therapeutics?

Enliven Therapeutics (NASDAQ:ELVN) and Esperion Therapeutics (NASDAQ:ESPR) are both medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their profitability, earnings, institutional ownership, media sentiment, valuation, risk, analyst recommendations and dividends.

Enliven Therapeutics presently has a consensus target price of $70.50, suggesting a potential upside of 33.40%. Esperion Therapeutics has a consensus target price of $5.54, suggesting a potential upside of 74.21%. Given Esperion Therapeutics' higher probable upside, analysts clearly believe Esperion Therapeutics is more favorable than Enliven Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Enliven Therapeutics
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.86
Esperion Therapeutics
1 Sell rating(s)
6 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Enliven Therapeutics has a beta of 0.24, indicating that its share price is 76% less volatile than the broader market. Comparatively, Esperion Therapeutics has a beta of 1.07, indicating that its share price is 7% more volatile than the broader market.

In the previous week, Enliven Therapeutics had 7 more articles in the media than Esperion Therapeutics. MarketBeat recorded 8 mentions for Enliven Therapeutics and 1 mentions for Esperion Therapeutics. Enliven Therapeutics' average media sentiment score of 0.80 beat Esperion Therapeutics' score of 0.51 indicating that Enliven Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Enliven Therapeutics
3 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Esperion Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Esperion Therapeutics has higher revenue and earnings than Enliven Therapeutics. Esperion Therapeutics is trading at a lower price-to-earnings ratio than Enliven Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Enliven TherapeuticsN/AN/A-$103.69M-$1.67N/A
Esperion Therapeutics$403.14M2.03-$22.68M-$0.06N/A

95.1% of Enliven Therapeutics shares are held by institutional investors. Comparatively, 47.4% of Esperion Therapeutics shares are held by institutional investors. 3.0% of Enliven Therapeutics shares are held by company insiders. Comparatively, 1.6% of Esperion Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Esperion Therapeutics has a net margin of 0.12% compared to Enliven Therapeutics' net margin of 0.00%. Esperion Therapeutics' return on equity of -0.14% beat Enliven Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Enliven TherapeuticsN/A -21.04% -20.41%
Esperion Therapeutics 0.12%-0.14%0.12%

Summary

Enliven Therapeutics and Esperion Therapeutics tied by winning 8 of the 16 factors compared between the two stocks.

How does Esperion Therapeutics compare to IDEAYA Biosciences?

Esperion Therapeutics (NASDAQ:ESPR) and IDEAYA Biosciences (NASDAQ:IDYA) are both medical companies, but which is the better business? We will contrast the two businesses based on the strength of their profitability, analyst recommendations, institutional ownership, risk, earnings, media sentiment, dividends and valuation.

47.4% of Esperion Therapeutics shares are held by institutional investors. Comparatively, 98.3% of IDEAYA Biosciences shares are held by institutional investors. 1.6% of Esperion Therapeutics shares are held by company insiders. Comparatively, 4.7% of IDEAYA Biosciences shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Esperion Therapeutics currently has a consensus target price of $5.54, indicating a potential upside of 74.21%. IDEAYA Biosciences has a consensus target price of $50.25, indicating a potential upside of 43.57%. Given Esperion Therapeutics' higher probable upside, equities analysts plainly believe Esperion Therapeutics is more favorable than IDEAYA Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Esperion Therapeutics
1 Sell rating(s)
6 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
IDEAYA Biosciences
1 Sell rating(s)
1 Hold rating(s)
14 Buy rating(s)
0 Strong Buy rating(s)
2.81

Esperion Therapeutics has a net margin of 0.12% compared to IDEAYA Biosciences' net margin of 0.00%. Esperion Therapeutics' return on equity of -0.14% beat IDEAYA Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Esperion Therapeutics0.12% -0.14% 0.12%
IDEAYA Biosciences N/A -14.24%-13.09%

Esperion Therapeutics has a beta of 1.07, meaning that its share price is 7% more volatile than the broader market. Comparatively, IDEAYA Biosciences has a beta of -0.09, meaning that its share price is 109% less volatile than the broader market.

In the previous week, IDEAYA Biosciences had 5 more articles in the media than Esperion Therapeutics. MarketBeat recorded 6 mentions for IDEAYA Biosciences and 1 mentions for Esperion Therapeutics. IDEAYA Biosciences' average media sentiment score of 0.77 beat Esperion Therapeutics' score of 0.51 indicating that IDEAYA Biosciences is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Esperion Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
IDEAYA Biosciences
3 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Esperion Therapeutics has higher revenue and earnings than IDEAYA Biosciences. Esperion Therapeutics is trading at a lower price-to-earnings ratio than IDEAYA Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Esperion Therapeutics$403.14M2.03-$22.68M-$0.06N/A
IDEAYA Biosciences$218.71M14.06-$113.70M-$1.60N/A

Summary

Esperion Therapeutics and IDEAYA Biosciences tied by winning 8 of the 16 factors compared between the two stocks.

How does Esperion Therapeutics compare to MBX Biosciences?

MBX Biosciences (NASDAQ:MBX) and Esperion Therapeutics (NASDAQ:ESPR) are both pharmaceutical products companies, but which is the superior investment? We will contrast the two companies based on the strength of their dividends, earnings, media sentiment, valuation, institutional ownership, profitability, risk and analyst recommendations.

47.4% of Esperion Therapeutics shares are held by institutional investors. 31.1% of MBX Biosciences shares are held by insiders. Comparatively, 1.6% of Esperion Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Esperion Therapeutics has a net margin of 0.12% compared to MBX Biosciences' net margin of 0.00%. Esperion Therapeutics' return on equity of -0.14% beat MBX Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
MBX BiosciencesN/A -24.52% -23.59%
Esperion Therapeutics 0.12%-0.14%0.12%

In the previous week, MBX Biosciences had 2 more articles in the media than Esperion Therapeutics. MarketBeat recorded 3 mentions for MBX Biosciences and 1 mentions for Esperion Therapeutics. Esperion Therapeutics' average media sentiment score of 0.51 beat MBX Biosciences' score of -0.19 indicating that Esperion Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
MBX Biosciences
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Esperion Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Esperion Therapeutics has higher revenue and earnings than MBX Biosciences. Esperion Therapeutics is trading at a lower price-to-earnings ratio than MBX Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
MBX BiosciencesN/AN/A-$86.97M-$2.21N/A
Esperion Therapeutics$403.14M2.03-$22.68M-$0.06N/A

MBX Biosciences has a beta of 0.16, suggesting that its share price is 84% less volatile than the broader market. Comparatively, Esperion Therapeutics has a beta of 1.07, suggesting that its share price is 7% more volatile than the broader market.

MBX Biosciences currently has a consensus price target of $63.00, indicating a potential upside of 8.06%. Esperion Therapeutics has a consensus price target of $5.54, indicating a potential upside of 74.21%. Given Esperion Therapeutics' higher probable upside, analysts plainly believe Esperion Therapeutics is more favorable than MBX Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
MBX Biosciences
2 Sell rating(s)
0 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.75
Esperion Therapeutics
1 Sell rating(s)
6 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Summary

Esperion Therapeutics beats MBX Biosciences on 10 of the 16 factors compared between the two stocks.

How does Esperion Therapeutics compare to Disc Medicine?

Disc Medicine (NASDAQ:IRON) and Esperion Therapeutics (NASDAQ:ESPR) are both medical companies, but which is the superior business? We will compare the two businesses based on the strength of their institutional ownership, profitability, dividends, valuation, analyst recommendations, media sentiment, risk and earnings.

Disc Medicine has a beta of 0.97, suggesting that its stock price is 3% less volatile than the broader market. Comparatively, Esperion Therapeutics has a beta of 1.07, suggesting that its stock price is 7% more volatile than the broader market.

Esperion Therapeutics has a net margin of 0.12% compared to Disc Medicine's net margin of 0.00%. Esperion Therapeutics' return on equity of -0.14% beat Disc Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Disc MedicineN/A -36.94% -33.88%
Esperion Therapeutics 0.12%-0.14%0.12%

83.7% of Disc Medicine shares are held by institutional investors. Comparatively, 47.4% of Esperion Therapeutics shares are held by institutional investors. 3.8% of Disc Medicine shares are held by company insiders. Comparatively, 1.6% of Esperion Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

In the previous week, Disc Medicine had 3 more articles in the media than Esperion Therapeutics. MarketBeat recorded 4 mentions for Disc Medicine and 1 mentions for Esperion Therapeutics. Disc Medicine's average media sentiment score of 0.62 beat Esperion Therapeutics' score of 0.51 indicating that Disc Medicine is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Disc Medicine
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Esperion Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Esperion Therapeutics has higher revenue and earnings than Disc Medicine. Esperion Therapeutics is trading at a lower price-to-earnings ratio than Disc Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Disc MedicineN/AN/A-$212.18M-$6.62N/A
Esperion Therapeutics$403.14M2.03-$22.68M-$0.06N/A

Disc Medicine currently has a consensus target price of $104.44, suggesting a potential upside of 40.53%. Esperion Therapeutics has a consensus target price of $5.54, suggesting a potential upside of 74.21%. Given Esperion Therapeutics' higher possible upside, analysts clearly believe Esperion Therapeutics is more favorable than Disc Medicine.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Disc Medicine
1 Sell rating(s)
1 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.73
Esperion Therapeutics
1 Sell rating(s)
6 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Summary

Esperion Therapeutics beats Disc Medicine on 8 of the 15 factors compared between the two stocks.

How does Esperion Therapeutics compare to Ultragenyx Pharmaceutical?

Esperion Therapeutics (NASDAQ:ESPR) and Ultragenyx Pharmaceutical (NASDAQ:RARE) are both medical companies, but which is the better investment? We will compare the two businesses based on the strength of their dividends, valuation, institutional ownership, earnings, analyst recommendations, risk, media sentiment and profitability.

47.4% of Esperion Therapeutics shares are owned by institutional investors. Comparatively, 97.7% of Ultragenyx Pharmaceutical shares are owned by institutional investors. 1.6% of Esperion Therapeutics shares are owned by insiders. Comparatively, 5.2% of Ultragenyx Pharmaceutical shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Esperion Therapeutics has a beta of 1.07, suggesting that its share price is 7% more volatile than the broader market. Comparatively, Ultragenyx Pharmaceutical has a beta of 0.31, suggesting that its share price is 69% less volatile than the broader market.

Esperion Therapeutics presently has a consensus target price of $5.54, suggesting a potential upside of 74.21%. Ultragenyx Pharmaceutical has a consensus target price of $58.41, suggesting a potential upside of 111.25%. Given Ultragenyx Pharmaceutical's stronger consensus rating and higher probable upside, analysts clearly believe Ultragenyx Pharmaceutical is more favorable than Esperion Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Esperion Therapeutics
1 Sell rating(s)
6 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
Ultragenyx Pharmaceutical
1 Sell rating(s)
2 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.83

Esperion Therapeutics has a net margin of 0.12% compared to Ultragenyx Pharmaceutical's net margin of -91.03%. Esperion Therapeutics' return on equity of -0.14% beat Ultragenyx Pharmaceutical's return on equity.

Company Net Margins Return on Equity Return on Assets
Esperion Therapeutics0.12% -0.14% 0.12%
Ultragenyx Pharmaceutical -91.03%-1,024.42%-45.78%

In the previous week, Esperion Therapeutics and Esperion Therapeutics both had 1 articles in the media. Ultragenyx Pharmaceutical's average media sentiment score of 0.80 beat Esperion Therapeutics' score of 0.51 indicating that Ultragenyx Pharmaceutical is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Esperion Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Ultragenyx Pharmaceutical
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Esperion Therapeutics has higher earnings, but lower revenue than Ultragenyx Pharmaceutical. Esperion Therapeutics is trading at a lower price-to-earnings ratio than Ultragenyx Pharmaceutical, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Esperion Therapeutics$403.14M2.03-$22.68M-$0.06N/A
Ultragenyx Pharmaceutical$673M4.05-$575M-$6.11N/A

Summary

Ultragenyx Pharmaceutical beats Esperion Therapeutics on 10 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ESPR and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ESPR vs. The Competition

MetricEsperion TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$819.45M$3.10B$7.01B$12.68B
Dividend YieldN/A2.04%2.67%9.42%
P/E Ratio-53.0019.8226.8223.95
Price / Sales2.03785.64576.32115.11
Price / CashN/A28.0850.6060.45
Price / Book-2.524.2110.526.16
Net Income-$22.68M$65.94M$3.60B$331.73M
7 Day PerformanceN/A-1.48%-1.34%-0.92%
1 Month Performance0.63%-1.92%-0.29%-2.23%
1 Year Performance139.10%10.99%18.96%14.79%

Esperion Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ESPR
Esperion Therapeutics
2.8668 of 5 stars
$3.18
flat
$5.54
+74.2%
N/A$819.45M$403.14MN/A200
ELVN
Enliven Therapeutics
3.3607 of 5 stars
$51.67
-2.9%
$69.17
+33.9%
+145.1%$3.24BN/AN/A50
IDYA
IDEAYA Biosciences
3.8808 of 5 stars
$35.45
-1.6%
$50.25
+41.7%
+58.9%$3.16B$218.71MN/A80
MBX
MBX Biosciences
1.2583 of 5 stars
$60.14
-4.4%
$63.00
+4.8%
N/A$2.99BN/AN/AN/A
IRON
Disc Medicine
2.3707 of 5 stars
$74.38
-2.3%
$104.44
+40.4%
+22.4%$2.91BN/AN/A30

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This page (NASDAQ:ESPR) was last updated on 7/23/2026 by MarketBeat.com Staff.
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