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Sionna Therapeutics (SION) Competitors

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$46.56 +0.87 (+1.90%)
As of 11:01 AM Eastern
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SION vs. RYTM, MIRM, LNTH, COGT, and ERAS

Should you buy Sionna Therapeutics stock or one of its competitors? MarketBeat compares Sionna Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Sionna Therapeutics include Rhythm Pharmaceuticals (RYTM), Mirum Pharmaceuticals (MIRM), Lantheus (LNTH), Cogent Biosciences (COGT), and Erasca (ERAS). These companies are all part of the "pharmaceutical products" industry.

How does Sionna Therapeutics compare to Rhythm Pharmaceuticals?

Sionna Therapeutics (NASDAQ:SION) and Rhythm Pharmaceuticals (NASDAQ:RYTM) are both mid-cap medical companies, but which is the superior stock? We will contrast the two companies based on the strength of their valuation, media sentiment, analyst recommendations, risk, dividends, institutional ownership, earnings and profitability.

In the previous week, Rhythm Pharmaceuticals had 2 more articles in the media than Sionna Therapeutics. MarketBeat recorded 6 mentions for Rhythm Pharmaceuticals and 4 mentions for Sionna Therapeutics. Sionna Therapeutics' average media sentiment score of 0.87 beat Rhythm Pharmaceuticals' score of 0.34 indicating that Sionna Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Sionna Therapeutics
1 Very Positive mention(s)
3 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Rhythm Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Sionna Therapeutics has a net margin of 0.00% compared to Rhythm Pharmaceuticals' net margin of -93.33%. Sionna Therapeutics' return on equity of -27.31% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Sionna TherapeuticsN/A -27.31% -25.88%
Rhythm Pharmaceuticals -93.33%-203.25%-44.99%

Sionna Therapeutics currently has a consensus price target of $53.22, suggesting a potential upside of 14.31%. Rhythm Pharmaceuticals has a consensus price target of $138.29, suggesting a potential upside of 29.62%. Given Rhythm Pharmaceuticals' higher possible upside, analysts plainly believe Rhythm Pharmaceuticals is more favorable than Sionna Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Sionna Therapeutics
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
2.85
Rhythm Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
14 Buy rating(s)
0 Strong Buy rating(s)
2.76

Sionna Therapeutics has higher earnings, but lower revenue than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Sionna Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Sionna TherapeuticsN/AN/A-$75.27M-$1.93N/A
Rhythm Pharmaceuticals$189.76M38.53-$196.54M-$3.13N/A

Sionna Therapeutics has a beta of 1.33, indicating that its stock price is 33% more volatile than the broader market. Comparatively, Rhythm Pharmaceuticals has a beta of 1.88, indicating that its stock price is 88% more volatile than the broader market.

Summary

Sionna Therapeutics beats Rhythm Pharmaceuticals on 9 of the 14 factors compared between the two stocks.

How does Sionna Therapeutics compare to Mirum Pharmaceuticals?

Mirum Pharmaceuticals (NASDAQ:MIRM) and Sionna Therapeutics (NASDAQ:SION) are both mid-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their institutional ownership, earnings, risk, dividends, media sentiment, valuation, analyst recommendations and profitability.

Mirum Pharmaceuticals has a beta of 0.48, meaning that its share price is 52% less volatile than the broader market. Comparatively, Sionna Therapeutics has a beta of 1.33, meaning that its share price is 33% more volatile than the broader market.

In the previous week, Sionna Therapeutics had 2 more articles in the media than Mirum Pharmaceuticals. MarketBeat recorded 4 mentions for Sionna Therapeutics and 2 mentions for Mirum Pharmaceuticals. Mirum Pharmaceuticals' average media sentiment score of 1.26 beat Sionna Therapeutics' score of 0.87 indicating that Mirum Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Mirum Pharmaceuticals
1 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Sionna Therapeutics
1 Very Positive mention(s)
3 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Sionna Therapeutics has a net margin of 0.00% compared to Mirum Pharmaceuticals' net margin of -140.24%. Mirum Pharmaceuticals' return on equity of -11.28% beat Sionna Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Mirum Pharmaceuticals-140.24% -11.28% -3.84%
Sionna Therapeutics N/A -27.31%-25.88%

Mirum Pharmaceuticals currently has a consensus target price of $143.40, indicating a potential upside of 22.98%. Sionna Therapeutics has a consensus target price of $53.22, indicating a potential upside of 14.31%. Given Mirum Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Mirum Pharmaceuticals is more favorable than Sionna Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mirum Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.93
Sionna Therapeutics
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
2.85

Mirum Pharmaceuticals has higher revenue and earnings than Sionna Therapeutics. Sionna Therapeutics is trading at a lower price-to-earnings ratio than Mirum Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Mirum Pharmaceuticals$521.31M13.64-$23.36M-$13.61N/A
Sionna TherapeuticsN/AN/A-$75.27M-$1.93N/A

Summary

Mirum Pharmaceuticals beats Sionna Therapeutics on 9 of the 14 factors compared between the two stocks.

How does Sionna Therapeutics compare to Lantheus?

Lantheus (NASDAQ:LNTH) and Sionna Therapeutics (NASDAQ:SION) are both mid-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their valuation, earnings, risk, profitability, analyst recommendations, institutional ownership, media sentiment and dividends.

99.1% of Lantheus shares are owned by institutional investors. 1.7% of Lantheus shares are owned by company insiders. Comparatively, 5.1% of Sionna Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

In the previous week, Lantheus had 2 more articles in the media than Sionna Therapeutics. MarketBeat recorded 6 mentions for Lantheus and 4 mentions for Sionna Therapeutics. Sionna Therapeutics' average media sentiment score of 0.87 beat Lantheus' score of 0.71 indicating that Sionna Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lantheus
3 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Sionna Therapeutics
1 Very Positive mention(s)
3 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Lantheus currently has a consensus target price of $110.43, suggesting a potential upside of 4.45%. Sionna Therapeutics has a consensus target price of $53.22, suggesting a potential upside of 14.31%. Given Sionna Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Sionna Therapeutics is more favorable than Lantheus.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lantheus
0 Sell rating(s)
3 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.73
Sionna Therapeutics
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
2.85

Lantheus has a net margin of 18.05% compared to Sionna Therapeutics' net margin of 0.00%. Lantheus' return on equity of 29.32% beat Sionna Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Lantheus18.05% 29.32% 15.00%
Sionna Therapeutics N/A -27.31%-25.88%

Lantheus has a beta of -0.06, suggesting that its share price is 106% less volatile than the broader market. Comparatively, Sionna Therapeutics has a beta of 1.33, suggesting that its share price is 33% more volatile than the broader market.

Lantheus has higher revenue and earnings than Sionna Therapeutics. Sionna Therapeutics is trading at a lower price-to-earnings ratio than Lantheus, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lantheus$1.55B4.45$233.56M$4.1525.48
Sionna TherapeuticsN/AN/A-$75.27M-$1.93N/A

Summary

Lantheus beats Sionna Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Sionna Therapeutics compare to Cogent Biosciences?

Sionna Therapeutics (NASDAQ:SION) and Cogent Biosciences (NASDAQ:COGT) are both mid-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their dividends, institutional ownership, earnings, media sentiment, profitability, analyst recommendations, risk and valuation.

In the previous week, Sionna Therapeutics had 2 more articles in the media than Cogent Biosciences. MarketBeat recorded 4 mentions for Sionna Therapeutics and 2 mentions for Cogent Biosciences. Sionna Therapeutics' average media sentiment score of 0.87 beat Cogent Biosciences' score of 0.45 indicating that Sionna Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Sionna Therapeutics
1 Very Positive mention(s)
3 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Cogent Biosciences
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Sionna Therapeutics has a beta of 1.33, meaning that its share price is 33% more volatile than the broader market. Comparatively, Cogent Biosciences has a beta of 0.34, meaning that its share price is 66% less volatile than the broader market.

Sionna Therapeutics' return on equity of -27.31% beat Cogent Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Sionna TherapeuticsN/A -27.31% -25.88%
Cogent Biosciences N/A -104.27%-54.64%

Sionna Therapeutics is trading at a lower price-to-earnings ratio than Cogent Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Sionna TherapeuticsN/AN/A-$75.27M-$1.93N/A
Cogent BiosciencesN/AN/A-$328.94M-$2.17N/A

Sionna Therapeutics currently has a consensus target price of $53.22, indicating a potential upside of 14.31%. Cogent Biosciences has a consensus target price of $45.90, indicating a potential upside of 18.24%. Given Cogent Biosciences' higher possible upside, analysts plainly believe Cogent Biosciences is more favorable than Sionna Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Sionna Therapeutics
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
2.85
Cogent Biosciences
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
2.85

Summary

Sionna Therapeutics beats Cogent Biosciences on 8 of the 11 factors compared between the two stocks.

How does Sionna Therapeutics compare to Erasca?

Sionna Therapeutics (NASDAQ:SION) and Erasca (NASDAQ:ERAS) are both mid-cap medical companies, but which is the better stock? We will contrast the two companies based on the strength of their institutional ownership, media sentiment, earnings, dividends, profitability, analyst recommendations, valuation and risk.

Sionna Therapeutics' return on equity of -27.31% beat Erasca's return on equity.

Company Net Margins Return on Equity Return on Assets
Sionna TherapeuticsN/A -27.31% -25.88%
Erasca N/A -35.31%-29.49%

Sionna Therapeutics has a beta of 1.33, meaning that its share price is 33% more volatile than the broader market. Comparatively, Erasca has a beta of 0.66, meaning that its share price is 34% less volatile than the broader market.

67.8% of Erasca shares are held by institutional investors. 5.1% of Sionna Therapeutics shares are held by insiders. Comparatively, 14.2% of Erasca shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

In the previous week, Erasca had 35 more articles in the media than Sionna Therapeutics. MarketBeat recorded 39 mentions for Erasca and 4 mentions for Sionna Therapeutics. Sionna Therapeutics' average media sentiment score of 0.87 beat Erasca's score of 0.13 indicating that Sionna Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Sionna Therapeutics
1 Very Positive mention(s)
3 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Erasca
4 Very Positive mention(s)
3 Positive mention(s)
29 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Neutral

Sionna Therapeutics presently has a consensus target price of $53.22, indicating a potential upside of 14.31%. Erasca has a consensus target price of $21.64, indicating a potential upside of 13.37%. Given Sionna Therapeutics' stronger consensus rating and higher probable upside, analysts clearly believe Sionna Therapeutics is more favorable than Erasca.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Sionna Therapeutics
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
2.85
Erasca
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.64

Sionna Therapeutics is trading at a lower price-to-earnings ratio than Erasca, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Sionna TherapeuticsN/AN/A-$75.27M-$1.93N/A
ErascaN/AN/A-$124.55M-$0.93N/A

Summary

Sionna Therapeutics beats Erasca on 8 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding SION and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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SION vs. The Competition

MetricSionna TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$2.11B$3.64B$6.80B$12.40B
Dividend YieldN/A2.16%2.67%9.39%
P/E Ratio-24.1620.6127.0824.12
Price / SalesN/A304.69516.4792.58
Price / CashN/A60.3126.6847.25
Price / Book6.778.0410.636.23
Net Income-$75.27M$23.81M$3.60B$331.53M
7 Day Performance9.32%-1.31%-1.08%-1.30%
1 Month Performance24.83%2.48%1.28%-1.40%
1 Year Performance166.97%44.40%24.71%18.15%

Sionna Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
SION
Sionna Therapeutics
1.9368 of 5 stars
$46.56
+1.9%
$53.22
+14.3%
+172.9%$2.11BN/AN/A35
RYTM
Rhythm Pharmaceuticals
2.9184 of 5 stars
$106.09
-3.3%
$138.29
+30.3%
+17.3%$7.52B$189.76MN/A140
MIRM
Mirum Pharmaceuticals
3.2352 of 5 stars
$117.36
-3.0%
$143.40
+22.2%
+124.6%$7.38B$521.31MN/A140
LNTH
Lantheus
2.8788 of 5 stars
$105.11
+0.8%
$110.43
+5.1%
+48.8%$6.79B$1.54B25.331,193
COGT
Cogent Biosciences
1.9524 of 5 stars
$37.94
-3.5%
$43.73
+15.3%
+206.6%$6.72BN/AN/A80

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This page (NASDAQ:SION) was last updated on 7/21/2026 by MarketBeat.com Staff.
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