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Sionna Therapeutics (SION) Competitors

Sionna Therapeutics logo
$4.66 -46.38 (-90.86%)
As of 03:57 PM Eastern
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SION vs. IMVT, PCVX, RYTM, IBRX, and COGT

Should you buy Sionna Therapeutics stock or one of its competitors? MarketBeat compares Sionna Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Sionna Therapeutics include Immunovant (IMVT), Vaxcyte (PCVX), Rhythm Pharmaceuticals (RYTM), ImmunityBio (IBRX), and Cogent Biosciences (COGT).

How does Sionna Therapeutics compare to Immunovant?

Sionna Therapeutics (NASDAQ:SION) and Immunovant (NASDAQ:IMVT) are both healthcare companies, but which is the better business? We will compare the two companies based on the strength of their analyst recommendations, institutional ownership, risk, media sentiment, profitability, valuation, dividends and earnings.

Sionna Therapeutics' return on equity of -32.94% beat Immunovant's return on equity.

Company Net Margins Return on Equity Return on Assets
Sionna TherapeuticsN/A -32.94% -31.08%
Immunovant N/A -69.59%-62.49%

Sionna Therapeutics has a beta of 1.32, suggesting that its stock price is 32% more volatile than the broader market. Comparatively, Immunovant has a beta of 0.77, suggesting that its stock price is 23% less volatile than the broader market.

Sionna Therapeutics presently has a consensus target price of $42.22, indicating a potential upside of 856.34%. Immunovant has a consensus target price of $44.00, indicating a potential upside of 11.03%. Given Sionna Therapeutics' higher probable upside, analysts plainly believe Sionna Therapeutics is more favorable than Immunovant.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Sionna Therapeutics
1 Sell rating(s)
8 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.31
Immunovant
1 Sell rating(s)
3 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.50

47.1% of Immunovant shares are owned by institutional investors. 5.1% of Sionna Therapeutics shares are owned by insiders. Comparatively, 1.9% of Immunovant shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Immunovant is trading at a lower price-to-earnings ratio than Sionna Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Sionna TherapeuticsN/AN/A-$75.27M-$2.18N/A
ImmunovantN/AN/A-$505.61M-$2.82N/A

In the previous week, Sionna Therapeutics had 10 more articles in the media than Immunovant. MarketBeat recorded 20 mentions for Sionna Therapeutics and 10 mentions for Immunovant. Immunovant's average media sentiment score of 0.27 beat Sionna Therapeutics' score of -0.18 indicating that Immunovant is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Sionna Therapeutics
1 Very Positive mention(s)
7 Positive mention(s)
2 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral
Immunovant
4 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Sionna Therapeutics beats Immunovant on 10 of the 14 factors compared between the two stocks.

How does Sionna Therapeutics compare to Vaxcyte?

Vaxcyte (NASDAQ:PCVX) and Sionna Therapeutics (NASDAQ:SION) are both healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their media sentiment, dividends, analyst recommendations, risk, valuation, profitability, institutional ownership and earnings.

Sionna Therapeutics' return on equity of -32.94% beat Vaxcyte's return on equity.

Company Net Margins Return on Equity Return on Assets
VaxcyteN/A -37.56% -33.62%
Sionna Therapeutics N/A -32.94%-31.08%

Vaxcyte presently has a consensus price target of $86.00, suggesting a potential upside of 47.15%. Sionna Therapeutics has a consensus price target of $42.22, suggesting a potential upside of 856.34%. Given Sionna Therapeutics' higher probable upside, analysts clearly believe Sionna Therapeutics is more favorable than Vaxcyte.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vaxcyte
2 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.38
Sionna Therapeutics
1 Sell rating(s)
8 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.31

96.8% of Vaxcyte shares are owned by institutional investors. 3.3% of Vaxcyte shares are owned by insiders. Comparatively, 5.1% of Sionna Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Vaxcyte has a beta of 1.23, indicating that its stock price is 23% more volatile than the broader market. Comparatively, Sionna Therapeutics has a beta of 1.32, indicating that its stock price is 32% more volatile than the broader market.

In the previous week, Vaxcyte and Vaxcyte both had 20 articles in the media. Vaxcyte's average media sentiment score of 0.68 beat Sionna Therapeutics' score of -0.18 indicating that Vaxcyte is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vaxcyte
10 Very Positive mention(s)
2 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Sionna Therapeutics
1 Very Positive mention(s)
7 Positive mention(s)
2 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral

Vaxcyte is trading at a lower price-to-earnings ratio than Sionna Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
VaxcyteN/AN/A-$766.63M-$7.63N/A
Sionna TherapeuticsN/AN/A-$75.27M-$2.18N/A

Summary

Sionna Therapeutics beats Vaxcyte on 9 of the 13 factors compared between the two stocks.

How does Sionna Therapeutics compare to Rhythm Pharmaceuticals?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and Sionna Therapeutics (NASDAQ:SION) are both healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their dividends, risk, valuation, media sentiment, analyst recommendations, earnings, institutional ownership and profitability.

Rhythm Pharmaceuticals currently has a consensus target price of $142.44, indicating a potential upside of 23.16%. Sionna Therapeutics has a consensus target price of $42.22, indicating a potential upside of 856.34%. Given Sionna Therapeutics' higher probable upside, analysts plainly believe Sionna Therapeutics is more favorable than Rhythm Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
15 Buy rating(s)
0 Strong Buy rating(s)
2.78
Sionna Therapeutics
1 Sell rating(s)
8 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.31

Sionna Therapeutics has a net margin of 0.00% compared to Rhythm Pharmaceuticals' net margin of -85.59%. Sionna Therapeutics' return on equity of -32.94% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-85.59% -159.87% -44.00%
Sionna Therapeutics N/A -32.94%-31.08%

Sionna Therapeutics has lower revenue, but higher earnings than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Sionna Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$189.76M41.77-$196.54M-$3.11N/A
Sionna TherapeuticsN/AN/A-$75.27M-$2.18N/A

In the previous week, Rhythm Pharmaceuticals had 5 more articles in the media than Sionna Therapeutics. MarketBeat recorded 25 mentions for Rhythm Pharmaceuticals and 20 mentions for Sionna Therapeutics. Rhythm Pharmaceuticals' average media sentiment score of 0.47 beat Sionna Therapeutics' score of -0.18 indicating that Rhythm Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rhythm Pharmaceuticals
6 Very Positive mention(s)
1 Positive mention(s)
12 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
Sionna Therapeutics
1 Very Positive mention(s)
7 Positive mention(s)
2 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral

Rhythm Pharmaceuticals has a beta of 1.92, meaning that its share price is 92% more volatile than the broader market. Comparatively, Sionna Therapeutics has a beta of 1.32, meaning that its share price is 32% more volatile than the broader market.

Summary

Sionna Therapeutics beats Rhythm Pharmaceuticals on 8 of the 14 factors compared between the two stocks.

How does Sionna Therapeutics compare to ImmunityBio?

ImmunityBio (NASDAQ:IBRX) and Sionna Therapeutics (NASDAQ:SION) are both healthcare companies, but which is the superior stock? We will contrast the two companies based on the strength of their earnings, risk, profitability, dividends, valuation, media sentiment, analyst recommendations and institutional ownership.

8.6% of ImmunityBio shares are owned by institutional investors. 66.1% of ImmunityBio shares are owned by company insiders. Comparatively, 5.1% of Sionna Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Sionna Therapeutics has a net margin of 0.00% compared to ImmunityBio's net margin of -598.55%. ImmunityBio's return on equity of 0.00% beat Sionna Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
ImmunityBio-598.55% N/A -51.65%
Sionna Therapeutics N/A -32.94%-31.08%

ImmunityBio has a beta of 0.03, indicating that its stock price is 97% less volatile than the broader market. Comparatively, Sionna Therapeutics has a beta of 1.32, indicating that its stock price is 32% more volatile than the broader market.

In the previous week, Sionna Therapeutics had 2 more articles in the media than ImmunityBio. MarketBeat recorded 20 mentions for Sionna Therapeutics and 18 mentions for ImmunityBio. ImmunityBio's average media sentiment score of 0.35 beat Sionna Therapeutics' score of -0.18 indicating that ImmunityBio is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
ImmunityBio
4 Very Positive mention(s)
5 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Sionna Therapeutics
1 Very Positive mention(s)
7 Positive mention(s)
2 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral

ImmunityBio currently has a consensus target price of $14.20, suggesting a potential upside of 89.71%. Sionna Therapeutics has a consensus target price of $42.22, suggesting a potential upside of 856.34%. Given Sionna Therapeutics' higher possible upside, analysts plainly believe Sionna Therapeutics is more favorable than ImmunityBio.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
ImmunityBio
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.71
Sionna Therapeutics
1 Sell rating(s)
8 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.31

Sionna Therapeutics has lower revenue, but higher earnings than ImmunityBio. ImmunityBio is trading at a lower price-to-earnings ratio than Sionna Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ImmunityBio$113.29M70.02-$351.40M-$0.97N/A
Sionna TherapeuticsN/AN/A-$75.27M-$2.18N/A

Summary

ImmunityBio and Sionna Therapeutics tied by winning 8 of the 16 factors compared between the two stocks.

How does Sionna Therapeutics compare to Cogent Biosciences?

Sionna Therapeutics (NASDAQ:SION) and Cogent Biosciences (NASDAQ:COGT) are both healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their earnings, dividends, institutional ownership, profitability, valuation, analyst recommendations, media sentiment and risk.

Cogent Biosciences is trading at a lower price-to-earnings ratio than Sionna Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Sionna TherapeuticsN/AN/A-$75.27M-$2.18N/A
Cogent BiosciencesN/AN/A-$328.94M-$2.17N/A

Sionna Therapeutics' return on equity of -32.94% beat Cogent Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Sionna TherapeuticsN/A -32.94% -31.08%
Cogent Biosciences N/A -104.27%-54.64%

Sionna Therapeutics has a beta of 1.32, meaning that its share price is 32% more volatile than the broader market. Comparatively, Cogent Biosciences has a beta of 0.38, meaning that its share price is 62% less volatile than the broader market.

Sionna Therapeutics currently has a consensus price target of $42.22, suggesting a potential upside of 856.34%. Cogent Biosciences has a consensus price target of $45.90, suggesting a potential upside of 11.37%. Given Sionna Therapeutics' higher probable upside, equities analysts clearly believe Sionna Therapeutics is more favorable than Cogent Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Sionna Therapeutics
1 Sell rating(s)
8 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.31
Cogent Biosciences
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
2.85

In the previous week, Sionna Therapeutics had 14 more articles in the media than Cogent Biosciences. MarketBeat recorded 20 mentions for Sionna Therapeutics and 6 mentions for Cogent Biosciences. Cogent Biosciences' average media sentiment score of 1.73 beat Sionna Therapeutics' score of -0.18 indicating that Cogent Biosciences is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Sionna Therapeutics
1 Very Positive mention(s)
7 Positive mention(s)
2 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral
Cogent Biosciences
4 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Summary

Sionna Therapeutics beats Cogent Biosciences on 7 of the 12 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding SION and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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SION vs. The Competition

MetricSionna TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$200.51M$3.71B$7.04B$12.94B
Dividend YieldN/A3.76%2.58%10.20%
P/E Ratio-2.039.08269.9824.78
Price / SalesN/A1,268.95651.07108.19
Price / CashN/A44.9528.8937.44
Price / Book0.6417.6511.266.43
Net Income-$75.27M-$13.25M$3.45B$347.27M
7 Day Performance-91.04%5.21%3.50%2.54%
1 Month Performance-90.25%-1.91%-0.64%-1.00%
1 Year Performance-75.01%60.70%77.23%23.33%

Sionna Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
SION
Sionna Therapeutics
2.9535 of 5 stars
$4.67
-90.9%
$42.22
+805.1%
+188.9%$210.91MN/AN/A35
IMVT
Immunovant
1.7722 of 5 stars
$39.49
+2.3%
$42.11
+6.6%
+158.4%$7.97BN/AN/A120
PCVX
Vaxcyte
2.732 of 5 stars
$55.96
+5.6%
$86.00
+53.7%
+94.2%$7.65BN/AN/A160
RYTM
Rhythm Pharmaceuticals
2.8132 of 5 stars
$105.74
-0.7%
$138.73
+31.2%
+25.7%$7.30B$189.76MN/A140
IBRX
ImmunityBio
2.3804 of 5 stars
$7.45
+9.1%
$14.20
+90.6%
+213.1%$7.15B$113.29MN/A590

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This page (NASDAQ:SION) was last updated on 8/10/2026 by MarketBeat.com Staff.
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