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Sionna Therapeutics (SION) Competitors

Sionna Therapeutics logo
$37.78 +1.08 (+2.94%)
Closing price 04:00 PM Eastern
Extended Trading
$37.84 +0.06 (+0.17%)
As of 07:07 PM Eastern
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SION vs. QGEN, PCVX, IMVT, KYMR, and PTGX

Should you buy Sionna Therapeutics stock or one of its competitors? MarketBeat compares Sionna Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Sionna Therapeutics include Qiagen (QGEN), Vaxcyte (PCVX), Immunovant (IMVT), Kymera Therapeutics (KYMR), and Protagonist Therapeutics (PTGX). These companies are all part of the "pharmaceutical products" industry.

How does Sionna Therapeutics compare to Qiagen?

Sionna Therapeutics (NASDAQ:SION) and Qiagen (NYSE:QGEN) are both medical companies, but which is the better business? We will compare the two businesses based on the strength of their analyst recommendations, media sentiment, risk, earnings, dividends, institutional ownership, profitability and valuation.

Qiagen has a net margin of 19.16% compared to Sionna Therapeutics' net margin of 0.00%. Qiagen's return on equity of 14.40% beat Sionna Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Sionna TherapeuticsN/A -27.31% -25.88%
Qiagen 19.16%14.40%8.40%

Sionna Therapeutics currently has a consensus target price of $53.22, indicating a potential upside of 40.87%. Qiagen has a consensus target price of $44.98, indicating a potential upside of 19.92%. Given Sionna Therapeutics' stronger consensus rating and higher probable upside, equities research analysts clearly believe Sionna Therapeutics is more favorable than Qiagen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Sionna Therapeutics
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
2.85
Qiagen
1 Sell rating(s)
6 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.42

In the previous week, Qiagen had 3 more articles in the media than Sionna Therapeutics. MarketBeat recorded 6 mentions for Qiagen and 3 mentions for Sionna Therapeutics. Sionna Therapeutics' average media sentiment score of 0.48 beat Qiagen's score of -0.41 indicating that Sionna Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Sionna Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Qiagen
1 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

70.0% of Qiagen shares are owned by institutional investors. 5.1% of Sionna Therapeutics shares are owned by insiders. Comparatively, 9.0% of Qiagen shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Qiagen has higher revenue and earnings than Sionna Therapeutics. Sionna Therapeutics is trading at a lower price-to-earnings ratio than Qiagen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Sionna TherapeuticsN/AN/A-$75.27M-$1.93N/A
Qiagen$2.09B3.70$424.88M$1.9119.64

Sionna Therapeutics has a beta of 1.3, suggesting that its stock price is 30% more volatile than the broader market. Comparatively, Qiagen has a beta of 0.66, suggesting that its stock price is 34% less volatile than the broader market.

Summary

Qiagen beats Sionna Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Sionna Therapeutics compare to Vaxcyte?

Vaxcyte (NASDAQ:PCVX) and Sionna Therapeutics (NASDAQ:SION) are both medical companies, but which is the superior investment? We will compare the two companies based on the strength of their earnings, profitability, dividends, analyst recommendations, valuation, institutional ownership, risk and media sentiment.

96.8% of Vaxcyte shares are held by institutional investors. 3.3% of Vaxcyte shares are held by company insiders. Comparatively, 5.1% of Sionna Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Vaxcyte has a beta of 1.24, indicating that its share price is 24% more volatile than the broader market. Comparatively, Sionna Therapeutics has a beta of 1.3, indicating that its share price is 30% more volatile than the broader market.

In the previous week, Vaxcyte had 2 more articles in the media than Sionna Therapeutics. MarketBeat recorded 5 mentions for Vaxcyte and 3 mentions for Sionna Therapeutics. Sionna Therapeutics' average media sentiment score of 0.48 beat Vaxcyte's score of 0.21 indicating that Sionna Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vaxcyte
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Sionna Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Vaxcyte presently has a consensus target price of $86.00, indicating a potential upside of 76.37%. Sionna Therapeutics has a consensus target price of $53.22, indicating a potential upside of 40.87%. Given Vaxcyte's higher possible upside, analysts clearly believe Vaxcyte is more favorable than Sionna Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vaxcyte
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.63
Sionna Therapeutics
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
2.85

Sionna Therapeutics' return on equity of -27.31% beat Vaxcyte's return on equity.

Company Net Margins Return on Equity Return on Assets
VaxcyteN/A -32.51% -29.51%
Sionna Therapeutics N/A -27.31%-25.88%

Sionna Therapeutics is trading at a lower price-to-earnings ratio than Vaxcyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
VaxcyteN/AN/A-$766.63M-$6.88N/A
Sionna TherapeuticsN/AN/A-$75.27M-$1.93N/A

Summary

Sionna Therapeutics beats Vaxcyte on 10 of the 14 factors compared between the two stocks.

How does Sionna Therapeutics compare to Immunovant?

Sionna Therapeutics (NASDAQ:SION) and Immunovant (NASDAQ:IMVT) are both medical companies, but which is the better business? We will contrast the two companies based on the strength of their earnings, dividends, institutional ownership, profitability, valuation, analyst recommendations, media sentiment and risk.

In the previous week, Immunovant had 2 more articles in the media than Sionna Therapeutics. MarketBeat recorded 5 mentions for Immunovant and 3 mentions for Sionna Therapeutics. Sionna Therapeutics' average media sentiment score of 0.48 beat Immunovant's score of 0.43 indicating that Sionna Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Sionna Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Immunovant
2 Very Positive mention(s)
2 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Sionna Therapeutics has a beta of 1.3, meaning that its share price is 30% more volatile than the broader market. Comparatively, Immunovant has a beta of 0.76, meaning that its share price is 24% less volatile than the broader market.

Sionna Therapeutics currently has a consensus price target of $53.22, suggesting a potential upside of 40.87%. Immunovant has a consensus price target of $37.33, suggesting a potential upside of 14.27%. Given Sionna Therapeutics' stronger consensus rating and higher probable upside, equities analysts clearly believe Sionna Therapeutics is more favorable than Immunovant.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Sionna Therapeutics
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
2.85
Immunovant
1 Sell rating(s)
4 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.45

Sionna Therapeutics is trading at a lower price-to-earnings ratio than Immunovant, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Sionna TherapeuticsN/AN/A-$75.27M-$1.93N/A
ImmunovantN/AN/A-$505.61M-$2.78N/A

47.1% of Immunovant shares are held by institutional investors. 5.1% of Sionna Therapeutics shares are held by company insiders. Comparatively, 1.8% of Immunovant shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Sionna Therapeutics' return on equity of -27.31% beat Immunovant's return on equity.

Company Net Margins Return on Equity Return on Assets
Sionna TherapeuticsN/A -27.31% -25.88%
Immunovant N/A -65.66%-59.88%

Summary

Sionna Therapeutics beats Immunovant on 11 of the 14 factors compared between the two stocks.

How does Sionna Therapeutics compare to Kymera Therapeutics?

Sionna Therapeutics (NASDAQ:SION) and Kymera Therapeutics (NASDAQ:KYMR) are both medical companies, but which is the superior business? We will contrast the two companies based on the strength of their valuation, earnings, profitability, media sentiment, dividends, analyst recommendations, risk and institutional ownership.

Sionna Therapeutics has higher earnings, but lower revenue than Kymera Therapeutics. Kymera Therapeutics is trading at a lower price-to-earnings ratio than Sionna Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Sionna TherapeuticsN/AN/A-$75.27M-$1.93N/A
Kymera Therapeutics$39.21M156.53-$311.35M-$3.57N/A

Sionna Therapeutics has a net margin of 0.00% compared to Kymera Therapeutics' net margin of -611.94%. Kymera Therapeutics' return on equity of -24.71% beat Sionna Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Sionna TherapeuticsN/A -27.31% -25.88%
Kymera Therapeutics -611.94%-24.71%-22.05%

In the previous week, Kymera Therapeutics had 1 more articles in the media than Sionna Therapeutics. MarketBeat recorded 4 mentions for Kymera Therapeutics and 3 mentions for Sionna Therapeutics. Kymera Therapeutics' average media sentiment score of 1.39 beat Sionna Therapeutics' score of 0.48 indicating that Kymera Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Sionna Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Kymera Therapeutics
2 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Sionna Therapeutics presently has a consensus price target of $53.22, suggesting a potential upside of 40.87%. Kymera Therapeutics has a consensus price target of $118.10, suggesting a potential upside of 58.28%. Given Kymera Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Kymera Therapeutics is more favorable than Sionna Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Sionna Therapeutics
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
2.85
Kymera Therapeutics
1 Sell rating(s)
0 Hold rating(s)
20 Buy rating(s)
1 Strong Buy rating(s)
2.95

Sionna Therapeutics has a beta of 1.3, indicating that its stock price is 30% more volatile than the broader market. Comparatively, Kymera Therapeutics has a beta of 2.02, indicating that its stock price is 102% more volatile than the broader market.

Summary

Kymera Therapeutics beats Sionna Therapeutics on 9 of the 14 factors compared between the two stocks.

How does Sionna Therapeutics compare to Protagonist Therapeutics?

Sionna Therapeutics (NASDAQ:SION) and Protagonist Therapeutics (NASDAQ:PTGX) are both medical companies, but which is the better stock? We will compare the two companies based on the strength of their institutional ownership, risk, valuation, profitability, media sentiment, earnings, analyst recommendations and dividends.

Sionna Therapeutics has higher earnings, but lower revenue than Protagonist Therapeutics. Protagonist Therapeutics is trading at a lower price-to-earnings ratio than Sionna Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Sionna TherapeuticsN/AN/A-$75.27M-$1.93N/A
Protagonist Therapeutics$46.02M143.64-$130.15M-$1.81N/A

Sionna Therapeutics has a beta of 1.3, meaning that its stock price is 30% more volatile than the broader market. Comparatively, Protagonist Therapeutics has a beta of 1.85, meaning that its stock price is 85% more volatile than the broader market.

Sionna Therapeutics has a net margin of 0.00% compared to Protagonist Therapeutics' net margin of -154.88%. Protagonist Therapeutics' return on equity of -17.76% beat Sionna Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Sionna TherapeuticsN/A -27.31% -25.88%
Protagonist Therapeutics -154.88%-17.76%-16.47%

In the previous week, Protagonist Therapeutics had 4 more articles in the media than Sionna Therapeutics. MarketBeat recorded 7 mentions for Protagonist Therapeutics and 3 mentions for Sionna Therapeutics. Protagonist Therapeutics' average media sentiment score of 0.72 beat Sionna Therapeutics' score of 0.48 indicating that Protagonist Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Sionna Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Protagonist Therapeutics
4 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Sionna Therapeutics currently has a consensus target price of $53.22, suggesting a potential upside of 40.87%. Protagonist Therapeutics has a consensus target price of $115.21, suggesting a potential upside of 12.09%. Given Sionna Therapeutics' higher probable upside, research analysts clearly believe Sionna Therapeutics is more favorable than Protagonist Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Sionna Therapeutics
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
2.85
Protagonist Therapeutics
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.88

98.6% of Protagonist Therapeutics shares are owned by institutional investors. 5.1% of Sionna Therapeutics shares are owned by insiders. Comparatively, 5.2% of Protagonist Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Summary

Protagonist Therapeutics beats Sionna Therapeutics on 11 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding SION and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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SION vs. The Competition

MetricSionna TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$1.66B$3.28B$6.30B$12.43B
Dividend YieldN/A2.36%2.69%5.33%
P/E Ratio-19.5818.4624.0324.35
Price / SalesN/A326.03523.15115.20
Price / CashN/A111.0341.3955.53
Price / Book5.496.779.986.72
Net Income-$75.27M$24.09M$3.56B$337.03M
7 Day Performance-11.73%-2.56%-0.89%0.09%
1 Month PerformanceN/AN/AN/A-1.78%
1 Year Performance139.11%48.90%28.76%33.98%

Sionna Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
SION
Sionna Therapeutics
2.6684 of 5 stars
$37.78
+2.9%
$53.22
+40.9%
+153.5%$1.66BN/AN/A35
QGEN
Qiagen
4.0143 of 5 stars
$36.65
+1.5%
$44.98
+22.7%
-23.5%$7.45B$2.09B19.145,654
PCVX
Vaxcyte
2.7673 of 5 stars
$51.06
+0.1%
$86.00
+68.4%
+35.4%$7.37BN/AN/A160
IMVT
Immunovant
2.07 of 5 stars
$33.50
+0.3%
$37.33
+11.4%
+101.7%$6.86BN/AN/A120
KYMR
Kymera Therapeutics
2.4221 of 5 stars
$81.46
-0.3%
$118.10
+45.0%
+67.9%$6.72B$39.21MN/A170

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This page (NASDAQ:SION) was last updated on 6/4/2026 by MarketBeat.com Staff.
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