Sionna Therapeutics (SION) Institutional Ownership

$5.96 -1.22 (-16.99%)

Closing price 09/18/2026 04:00 PM Eastern

Extended Trading

$6.03 +0.07 (+1.24%)

As of 09/18/2026 07:50 PM Eastern

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Number of Institutional Buyers (last 12 months): 59
Total Institutional Inflows (last 12 months): $244.50M

Number of Institutional Sellers (last 12 months): 23
Total Institutional Outflows (last 12 months): $175.61M

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SION Institutional Buying and Selling by Quarter

Sionna Therapeutics Major Shareholders & Ownership History

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Reporting Date	Major Shareholder Name	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
9/9/2026	Engineers Gate Manager LP	15,603	$686K	0.0%	N/A	0.035%
9/9/2026	Maven Securities LTD	20,000	$880K	0.0%	-20.0%	0.044%
9/9/2026	Squarepoint Ops LLC	5,415	$238K	0.0%	-64.4%	0.012%
8/21/2026	AXQ Capital LP	4,597	$202K	0.0%	N/A	0.010%
8/19/2026	UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	10,622	$467K	0.0%	+9,056.9%	0.023%
8/19/2026	Wellington Management Group LLP	37,365	$1.64M	0.0%	N/A	0.083%
8/17/2026	Artia Global Partners LP	119,741	$5.27M	1.0%	N/A	0.265%
8/17/2026	Bank of America Corp DE	88,908	$3.91M	0.0%	N/A	0.197%
8/15/2026	Jupiter Topco LLC	6,400	$281K	0.0%	N/A	0.014%
8/14/2026	Legal & General Group Plc	9,044	$398K	0.0%	N/A	0.020%
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8/14/2026	The Manufacturers Life Insurance Company	35,420	$1.56M	0.0%	N/A	0.078%
8/12/2026	Quantbot Technologies LP	1,820	$80K	0.0%	N/A	0.004%
8/7/2026	BlackRock Inc.	1,474,769	$64.88M	0.0%	N/A	3.266%
8/7/2026	Deutsche Bank AG	53,353	$2.35M	0.0%	N/A	0.118%
8/7/2026	Mitsubishi UFJ Asset Management Co. Ltd.	1,000	$44K	0.0%	N/A	0.002%
8/6/2026	Bank of New York Mellon Corp	41,586	$1.83M	0.0%	N/A	0.092%
8/6/2026	State of Wyoming	804	$35K	0.0%	N/A	0.002%
8/3/2026	Walleye Capital LLC	97,347	$4.28M	0.0%	N/A	0.216%
5/29/2026	Perceptive Advisors LLC	658,439	$26.40M	0.5%	-44.2%	1.458%
5/19/2026	Bank of America Corp DE	50,870	$2.04M	0.0%	+16.8%	0.113%
5/19/2026	Stempoint Capital LP	36,540	$1.47M	0.3%	N/A	0.081%
5/16/2026	The Manufacturers Life Insurance Company	64,458	$2.58M	0.0%	-7.2%	0.143%
5/16/2026	Orbimed Advisors LLC	3,530,702	$141.55M	2.6%	-0.9%	7.820%
5/14/2026	Walleye Capital LLC	15,097	$605K	0.0%	N/A	0.033%
5/7/2026	AlphaCentric Advisors LLC	4,818	$193K	0.2%	+77.1%	0.011%
5/6/2026	Jennison Associates LLC	1,451,220	$58.18M	0.0%	+30.1%	3.215%
5/5/2026	Bank of New York Mellon Corp	33,778	$1.35M	0.0%	-3.9%	0.075%
5/1/2026	Candriam S.C.A.	236,813	$9.49M	0.0%	N/A	0.525%
4/25/2026	Strs Ohio	2,900	$116K	0.0%	N/A	0.006%
2/19/2026	Invesco Ltd.	111,162	$4.57M	0.0%	N/A	0.249%
2/18/2026	XTX Topco Ltd	4,926	$203K	0.0%	N/A	0.011%
2/18/2026	Virtus Investment Advisers LLC	6,220	$256K	0.1%	-7.1%	0.014%
2/18/2026	Wellington Management Group LLP	38,347	$1.58M	0.0%	-9.2%	0.086%
2/18/2026	Superstring Capital Management LP	180,593	$7.43M	4.0%	N/A	0.405%
2/18/2026	Orbimed Advisors LLC	3,561,655	$146.53M	3.1%	-3.9%	7.981%
2/18/2026	Millennium Management LLC	80,546	$3.31M	0.0%	-62.4%	0.180%
2/18/2026	Artia Global Partners LP	119,741	$4.93M	0.7%	N/A	0.268%
2/18/2026	Balyasny Asset Management L.P.	1,406	$58K	0.0%	N/A	0.003%
2/17/2026	RA Capital Management L.P.	9,905,045	$407.49M	4.2%	-5.2%	22.194%
2/17/2026	Price T Rowe Associates Inc. MD	831,373	$34.20M	0.0%	+30.4%	1.863%
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2/17/2026	Russell Investments Group Ltd.	21,941	$903K	0.0%	+2,046.9%	0.049%
2/16/2026	Squarepoint Ops LLC	16,360	$673K	0.0%	+61.0%	0.037%
2/16/2026	Kennedy Capital Management LLC	6,752	$278K	0.0%	N/A	0.015%
2/16/2026	Eventide Asset Management LLC	639,045	$26.29M	0.4%	N/A	1.432%
2/16/2026	Barclays PLC	48,172	$1.98M	0.0%	+173.0%	0.108%
2/13/2026	The Manufacturers Life Insurance Company	69,424	$2.87M	0.0%	+116.4%	0.156%
2/13/2026	Kalehua Capital Management LLC	197,072	$8.11M	7.5%	N/A	0.442%
2/13/2026	Rafferty Asset Management LLC	24,690	$1.02M	0.0%	N/A	0.055%
2/13/2026	Alyeska Investment Group L.P.	136,222	$5.60M	0.0%	-26.8%	0.305%
2/13/2026	Siren L.L.C.	300,000	$12.34M	0.4%	-7.7%	0.672%
2/13/2026	Charles Schwab Investment Management Inc.	123,686	$5.09M	0.0%	+10.9%	0.277%
2/13/2026	Police & Firemen s Retirement System of New Jersey	4,232	$174K	0.0%	+30.9%	0.009%
2/13/2026	State Street Corp	693,395	$28.53M	0.0%	+188.7%	1.554%
2/13/2026	Wells Fargo & Company MN	17,551	$722K	0.0%	+131.7%	0.039%
2/13/2026	Atlas Venture Life Science Advisors LLC	2,995,602	$123.24M	14.2%	-17.1%	6.712%
2/12/2026	MetLife Investment Management LLC	8,565	$352K	0.0%	+6.6%	0.019%
2/12/2026	Ensign Peak Advisors Inc	79,862	$3.29M	0.0%	N/A	0.179%
2/12/2026	AlphaCentric Advisors LLC	2,720	$112K	0.1%	N/A	0.006%
2/12/2026	CIBC Private Wealth Group LLC	4,500	$185K	0.0%	N/A	0.010%
2/12/2026	Alps Advisors Inc.	36,648	$1.51M	0.0%	N/A	0.082%
2/12/2026	Nuveen LLC	23,734	$976K	0.0%	+48.0%	0.053%
2/11/2026	Deutsche Bank AG	10,029	$413K	0.0%	+4.5%	0.022%
2/11/2026	Franklin Resources Inc.	175,483	$7.22M	0.0%	-27.5%	0.393%
2/11/2026	JPMorgan Chase & Co.	1,231,819	$50.68M	0.0%	-37.7%	2.760%
2/11/2026	Los Angeles Capital Management LLC	5,189	$197K	0.0%	N/A	0.012%
2/10/2026	TD Asset Management Inc	113,352	$4.66M	0.0%	+30.2%	0.254%
2/10/2026	Goldman Sachs Group Inc.	36,269	$1.49M	0.0%	+197.8%	0.081%
2/10/2026	Seven Grand Managers LLC	50,000	$2.06M	0.2%	N/A	0.112%
2/9/2026	Geode Capital Management LLC	380,042	$15.64M	0.0%	+20.1%	0.852%
2/6/2026	ProShare Advisors LLC	4,903	$202K	0.0%	N/A	0.011%
1/30/2026	Jennison Associates LLC	1,115,278	$45.88M	0.0%	+11.8%	2.499%
1/29/2026	UBS Group AG	89,177	$3.67M	0.0%	+91.1%	0.200%
1/29/2026	Vanguard Group Inc.	1,184,951	$48.75M	0.0%	+3.7%	2.655%
1/29/2026	China Universal Asset Management Co. Ltd.	10,272	$423K	0.0%	+105.4%	0.023%
1/27/2026	GF Fund Management CO. LTD.	876	$36K	0.0%	N/A	0.002%
1/26/2026	Mirae Asset Global Investments Co. Ltd.	2,169	$89K	0.0%	N/A	0.005%
1/16/2026	Aberdeen Group plc	839,960	$34.56M	0.1%	-11.6%	1.882%
1/9/2026	SG Americas Securities LLC	10,691	$440K	0.0%	N/A	0.024%
11/26/2025	JPMorgan Chase & Co.	1,978,626	$58.19M	0.0%	-10.9%	4.433%
11/17/2025	Millennium Management LLC	214,085	$6.30M	0.0%	+1,425.5%	0.480%
11/17/2025	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	5,643	$166K	0.0%	-16.4%	0.013%
11/17/2025	Jain Global LLC	8,513	$250K	0.0%	N/A	0.019%
11/17/2025	Citadel Advisors LLC	35,923	$1.06M	0.0%	-72.3%	0.080%
11/17/2025	Bank of America Corp DE	6,541	$192K	0.0%	+8.8%	0.015%
11/17/2025	Braidwell LP	314,013	$9.24M	0.3%	-71.0%	0.704%
11/17/2025	Ameriprise Financial Inc.	153,151	$4.50M	0.0%	-35.3%	0.343%
11/14/2025	Longaeva Partners L.P.	61,457	$1.81M	0.3%	N/A	0.138%
11/14/2025	Squarepoint Ops LLC	10,162	$299K	0.0%	N/A	0.023%
11/14/2025	Atlas Venture Life Science Advisors LLC	3,615,527	$106.33M	14.1%	-2.1%	8.101%
11/13/2025	UBS Group AG	46,666	$1.37M	0.0%	-9.2%	0.105%
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11/13/2025	BNP Paribas Financial Markets	2,380	$70K	0.0%	+35.2%	0.005%
11/13/2025	Franklin Resources Inc.	242,147	$7.12M	0.0%	-51.6%	0.543%
11/13/2025	Legal & General Group Plc	7,374	$217K	0.0%	+436.7%	0.017%
11/13/2025	Russell Investments Group Ltd.	1,022	$30K	0.0%	N/A	0.002%
11/12/2025	Intech Investment Management LLC	7,486	$220K	0.0%	N/A	0.017%
11/10/2025	TD Asset Management Inc	87,082	$2.56M	0.0%	+74.3%	0.195%
11/10/2025	China Universal Asset Management Co. Ltd.	5,000	$147K	0.0%	N/A	0.011%
11/7/2025	Vanguard Group Inc.	1,143,154	$33.62M	0.0%	+81.4%	2.590%
11/7/2025	JPMorgan Chase & Co.	1,978,626	$58.19M	0.0%	-10.9%	4.483%
11/6/2025	Rhumbline Advisers	17,240	$507K	0.0%	-2.4%	0.039%

SION Institutional Ownership - Frequently Asked Questions

During the previous two years, 86 institutional investors and hedge funds held shares of Sionna Therapeutics. The most heavily invested institutionals were RA Capital Management L.P. ($407.49M), Orbimed Advisors LLC ($141.55M), Atlas Venture Life Science Advisors LLC ($123.24M), TPG GP A LLC ($69.93M), BlackRock Inc. ($64.88M), Jennison Associates LLC ($58.18M), and Viking Global Investors LP ($55.44M).Learn more on Sionna Therapeutics' institutional investors.

Of the 81 institutional investors that purchased Sionna Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: RA Capital Management L.P. ($10.45M), TPG GP A LLC ($6.68M), Atlas Venture Life Science Advisors LLC ($3.69M), BlackRock Inc. ($1.47M), Jennison Associates LLC ($1.31M), Braidwell LP ($1.08M), and Aberdeen Group plc ($950.55K).

Institutional investors have bought a total of 6,063,602 shares in the last 24 months. This purchase volume represents approximately $244.50M in transactions.

Of the 23 institutional investors that sold Sionna Therapeutics' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: JPMorgan Chase & Co. ($1.23M), Braidwell LP ($767.84K), Atlas Venture Life Science Advisors LLC ($698.42K), RA Capital Management L.P. ($540.28K), Perceptive Advisors LLC ($520.66K), Franklin Resources Inc. ($324.54K), and Orbimed Advisors LLC ($174.26K).

Institutional investors have sold a total of 4,787,925 shares in the last 24 months. This volume of shares sold represents approximately $175.61M in transactions.

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Institutional ownership data for NASDAQ:SION is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 9/9/2026. New 13F filings are added each quarter as they're published.

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Sionna Therapeutics (SION) Institutional Ownership

SION Institutional Buying and Selling by Quarter

Sionna Therapeutics Major Shareholders & Ownership History

SION Institutional Ownership - Frequently Asked Questions

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Sionna Therapeutics (SION) Institutional Ownership

Institutional Ownership Changes (13F Filings) for Sionna Therapeutics (NASDAQ:SION)

SION Institutional Buying and Selling by Quarter

Sionna Therapeutics Major Shareholders & Ownership History

SION Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of SION shares?

Which institutional investors have been buying Sionna Therapeutics' stock?

How much institutional buying is happening at Sionna Therapeutics?

Which of Sionna Therapeutics' major shareholders have been selling company stock?

How much institutional selling is happening at Sionna Therapeutics?

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