| 9/9/2026 | Engineers Gate Manager LP | 15,603 | $686K | 0.0% | N/A | 0.035% | |
| 9/9/2026 | Maven Securities LTD | 20,000 | $880K | 0.0% | -20.0% | 0.044% | |
| 9/9/2026 | Squarepoint Ops LLC | 5,415 | $238K | 0.0% | -64.4% | 0.012% | |
| 8/21/2026 | AXQ Capital LP | 4,597 | $202K | 0.0% | N/A | 0.010% | |
| 8/19/2026 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 10,622 | $467K | 0.0% | +9,056.9% | 0.023% | |
| 8/19/2026 | Wellington Management Group LLP | 37,365 | $1.64M | 0.0% | N/A | 0.083% | |
| 8/17/2026 | Artia Global Partners LP | 119,741 | $5.27M | 1.0% | N/A | 0.265% | |
| 8/17/2026 | Bank of America Corp DE | 88,908 | $3.91M | 0.0% | N/A | 0.197% | |
| 8/15/2026 | Jupiter Topco LLC | 6,400 | $281K | 0.0% | N/A | 0.014% | |
| 8/14/2026 | Legal & General Group Plc | 9,044 | $398K | 0.0% | N/A | 0.020% | |
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| 8/14/2026 | The Manufacturers Life Insurance Company | 35,420 | $1.56M | 0.0% | N/A | 0.078% | |
| 8/12/2026 | Quantbot Technologies LP | 1,820 | $80K | 0.0% | N/A | 0.004% | |
| 8/7/2026 | BlackRock Inc. | 1,474,769 | $64.88M | 0.0% | N/A | 3.266% | |
| 8/7/2026 | Deutsche Bank AG | 53,353 | $2.35M | 0.0% | N/A | 0.118% | |
| 8/7/2026 | Mitsubishi UFJ Asset Management Co. Ltd. | 1,000 | $44K | 0.0% | N/A | 0.002% | |
| 8/6/2026 | Bank of New York Mellon Corp | 41,586 | $1.83M | 0.0% | N/A | 0.092% | |
| 8/6/2026 | State of Wyoming | 804 | $35K | 0.0% | N/A | 0.002% | |
| 8/3/2026 | Walleye Capital LLC | 97,347 | $4.28M | 0.0% | N/A | 0.216% | |
| 5/29/2026 | Perceptive Advisors LLC | 658,439 | $26.40M | 0.5% | -44.2% | 1.458% | |
| 5/19/2026 | Bank of America Corp DE | 50,870 | $2.04M | 0.0% | +16.8% | 0.113% | |
| 5/19/2026 | Stempoint Capital LP | 36,540 | $1.47M | 0.3% | N/A | 0.081% | |
| 5/16/2026 | The Manufacturers Life Insurance Company | 64,458 | $2.58M | 0.0% | -7.2% | 0.143% | |
| 5/16/2026 | Orbimed Advisors LLC | 3,530,702 | $141.55M | 2.6% | -0.9% | 7.820% | |
| 5/14/2026 | Walleye Capital LLC | 15,097 | $605K | 0.0% | N/A | 0.033% | |
| 5/7/2026 | AlphaCentric Advisors LLC | 4,818 | $193K | 0.2% | +77.1% | 0.011% | |
| 5/6/2026 | Jennison Associates LLC | 1,451,220 | $58.18M | 0.0% | +30.1% | 3.215% | |
| 5/5/2026 | Bank of New York Mellon Corp | 33,778 | $1.35M | 0.0% | -3.9% | 0.075% | |
| 5/1/2026 | Candriam S.C.A. | 236,813 | $9.49M | 0.0% | N/A | 0.525% | |
| 4/25/2026 | Strs Ohio | 2,900 | $116K | 0.0% | N/A | 0.006% | |
| 2/19/2026 | Invesco Ltd. | 111,162 | $4.57M | 0.0% | N/A | 0.249% | |
| 2/18/2026 | XTX Topco Ltd | 4,926 | $203K | 0.0% | N/A | 0.011% | |
| 2/18/2026 | Virtus Investment Advisers LLC | 6,220 | $256K | 0.1% | -7.1% | 0.014% | |
| 2/18/2026 | Wellington Management Group LLP | 38,347 | $1.58M | 0.0% | -9.2% | 0.086% | |
| 2/18/2026 | Superstring Capital Management LP | 180,593 | $7.43M | 4.0% | N/A | 0.405% | |
| 2/18/2026 | Orbimed Advisors LLC | 3,561,655 | $146.53M | 3.1% | -3.9% | 7.981% | |
| 2/18/2026 | Millennium Management LLC | 80,546 | $3.31M | 0.0% | -62.4% | 0.180% | |
| 2/18/2026 | Artia Global Partners LP | 119,741 | $4.93M | 0.7% | N/A | 0.268% | |
| 2/18/2026 | Balyasny Asset Management L.P. | 1,406 | $58K | 0.0% | N/A | 0.003% | |
| 2/17/2026 | RA Capital Management L.P. | 9,905,045 | $407.49M | 4.2% | -5.2% | 22.194% | |
| 2/17/2026 | Price T Rowe Associates Inc. MD | 831,373 | $34.20M | 0.0% | +30.4% | 1.863% | |
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| 2/17/2026 | Russell Investments Group Ltd. | 21,941 | $903K | 0.0% | +2,046.9% | 0.049% | |
| 2/16/2026 | Squarepoint Ops LLC | 16,360 | $673K | 0.0% | +61.0% | 0.037% | |
| 2/16/2026 | Kennedy Capital Management LLC | 6,752 | $278K | 0.0% | N/A | 0.015% | |
| 2/16/2026 | Eventide Asset Management LLC | 639,045 | $26.29M | 0.4% | N/A | 1.432% | |
| 2/16/2026 | Barclays PLC | 48,172 | $1.98M | 0.0% | +173.0% | 0.108% | |
| 2/13/2026 | The Manufacturers Life Insurance Company | 69,424 | $2.87M | 0.0% | +116.4% | 0.156% | |
| 2/13/2026 | Kalehua Capital Management LLC | 197,072 | $8.11M | 7.5% | N/A | 0.442% | |
| 2/13/2026 | Rafferty Asset Management LLC | 24,690 | $1.02M | 0.0% | N/A | 0.055% | |
| 2/13/2026 | Alyeska Investment Group L.P. | 136,222 | $5.60M | 0.0% | -26.8% | 0.305% | |
| 2/13/2026 | Siren L.L.C. | 300,000 | $12.34M | 0.4% | -7.7% | 0.672% | |
| 2/13/2026 | Charles Schwab Investment Management Inc. | 123,686 | $5.09M | 0.0% | +10.9% | 0.277% | |
| 2/13/2026 | Police & Firemen s Retirement System of New Jersey | 4,232 | $174K | 0.0% | +30.9% | 0.009% | |
| 2/13/2026 | State Street Corp | 693,395 | $28.53M | 0.0% | +188.7% | 1.554% | |
| 2/13/2026 | Wells Fargo & Company MN | 17,551 | $722K | 0.0% | +131.7% | 0.039% | |
| 2/13/2026 | Atlas Venture Life Science Advisors LLC | 2,995,602 | $123.24M | 14.2% | -17.1% | 6.712% | |
| 2/12/2026 | MetLife Investment Management LLC | 8,565 | $352K | 0.0% | +6.6% | 0.019% | |
| 2/12/2026 | Ensign Peak Advisors Inc | 79,862 | $3.29M | 0.0% | N/A | 0.179% | |
| 2/12/2026 | AlphaCentric Advisors LLC | 2,720 | $112K | 0.1% | N/A | 0.006% | |
| 2/12/2026 | CIBC Private Wealth Group LLC | 4,500 | $185K | 0.0% | N/A | 0.010% | |
| 2/12/2026 | Alps Advisors Inc. | 36,648 | $1.51M | 0.0% | N/A | 0.082% | |
| 2/12/2026 | Nuveen LLC | 23,734 | $976K | 0.0% | +48.0% | 0.053% | |
| 2/11/2026 | Deutsche Bank AG | 10,029 | $413K | 0.0% | +4.5% | 0.022% | |
| 2/11/2026 | Franklin Resources Inc. | 175,483 | $7.22M | 0.0% | -27.5% | 0.393% | |
| 2/11/2026 | JPMorgan Chase & Co. | 1,231,819 | $50.68M | 0.0% | -37.7% | 2.760% | |
| 2/11/2026 | Los Angeles Capital Management LLC | 5,189 | $197K | 0.0% | N/A | 0.012% | |
| 2/10/2026 | TD Asset Management Inc | 113,352 | $4.66M | 0.0% | +30.2% | 0.254% | |
| 2/10/2026 | Goldman Sachs Group Inc. | 36,269 | $1.49M | 0.0% | +197.8% | 0.081% | |
| 2/10/2026 | Seven Grand Managers LLC | 50,000 | $2.06M | 0.2% | N/A | 0.112% | |
| 2/9/2026 | Geode Capital Management LLC | 380,042 | $15.64M | 0.0% | +20.1% | 0.852% | |
| 2/6/2026 | ProShare Advisors LLC | 4,903 | $202K | 0.0% | N/A | 0.011% | |
| 1/30/2026 | Jennison Associates LLC | 1,115,278 | $45.88M | 0.0% | +11.8% | 2.499% | |
| 1/29/2026 | UBS Group AG | 89,177 | $3.67M | 0.0% | +91.1% | 0.200% | |
| 1/29/2026 | Vanguard Group Inc. | 1,184,951 | $48.75M | 0.0% | +3.7% | 2.655% | |
| 1/29/2026 | China Universal Asset Management Co. Ltd. | 10,272 | $423K | 0.0% | +105.4% | 0.023% | |
| 1/27/2026 | GF Fund Management CO. LTD. | 876 | $36K | 0.0% | N/A | 0.002% | |
| 1/26/2026 | Mirae Asset Global Investments Co. Ltd. | 2,169 | $89K | 0.0% | N/A | 0.005% | |
| 1/16/2026 | Aberdeen Group plc | 839,960 | $34.56M | 0.1% | -11.6% | 1.882% | |
| 1/9/2026 | SG Americas Securities LLC | 10,691 | $440K | 0.0% | N/A | 0.024% | |
| 11/26/2025 | JPMorgan Chase & Co. | 1,978,626 | $58.19M | 0.0% | -10.9% | 4.433% | |
| 11/17/2025 | Millennium Management LLC | 214,085 | $6.30M | 0.0% | +1,425.5% | 0.480% | |
| 11/17/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 5,643 | $166K | 0.0% | -16.4% | 0.013% | |
| 11/17/2025 | Jain Global LLC | 8,513 | $250K | 0.0% | N/A | 0.019% | |
| 11/17/2025 | Citadel Advisors LLC | 35,923 | $1.06M | 0.0% | -72.3% | 0.080% | |
| 11/17/2025 | Bank of America Corp DE | 6,541 | $192K | 0.0% | +8.8% | 0.015% | |
| 11/17/2025 | Braidwell LP | 314,013 | $9.24M | 0.3% | -71.0% | 0.704% | |
| 11/17/2025 | Ameriprise Financial Inc. | 153,151 | $4.50M | 0.0% | -35.3% | 0.343% | |
| 11/14/2025 | Longaeva Partners L.P. | 61,457 | $1.81M | 0.3% | N/A | 0.138% | |
| 11/14/2025 | Squarepoint Ops LLC | 10,162 | $299K | 0.0% | N/A | 0.023% | |
| 11/14/2025 | Atlas Venture Life Science Advisors LLC | 3,615,527 | $106.33M | 14.1% | -2.1% | 8.101% | |
| 11/13/2025 | UBS Group AG | 46,666 | $1.37M | 0.0% | -9.2% | 0.105% | |
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| 11/13/2025 | BNP Paribas Financial Markets | 2,380 | $70K | 0.0% | +35.2% | 0.005% | |
| 11/13/2025 | Franklin Resources Inc. | 242,147 | $7.12M | 0.0% | -51.6% | 0.543% | |
| 11/13/2025 | Legal & General Group Plc | 7,374 | $217K | 0.0% | +436.7% | 0.017% | |
| 11/13/2025 | Russell Investments Group Ltd. | 1,022 | $30K | 0.0% | N/A | 0.002% | |
| 11/12/2025 | Intech Investment Management LLC | 7,486 | $220K | 0.0% | N/A | 0.017% | |
| 11/10/2025 | TD Asset Management Inc | 87,082 | $2.56M | 0.0% | +74.3% | 0.195% | |
| 11/10/2025 | China Universal Asset Management Co. Ltd. | 5,000 | $147K | 0.0% | N/A | 0.011% | |
| 11/7/2025 | Vanguard Group Inc. | 1,143,154 | $33.62M | 0.0% | +81.4% | 2.590% | |
| 11/7/2025 | JPMorgan Chase & Co. | 1,978,626 | $58.19M | 0.0% | -10.9% | 4.483% | |
| 11/6/2025 | Rhumbline Advisers | 17,240 | $507K | 0.0% | -2.4% | 0.039% | |