| 07/09/2026 3:44 PM | ORBIMED ADVISORS LLC (1055951) Reporting OrbiMed Capital GP VIII LLC (1845804) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 07/09/2026 3:47 PM | Sionna Therapeutics (2036042) Issuer Thompson Peter A. (1357522) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 07/07/2026 3:38 PM | Fitzpatrick Jennifer (2061851) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 07/06/2026 3:39 PM | Fitzpatrick Jennifer (2061851) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 07/02/2026 3:42 PM | ORBIMED ADVISORS LLC (1055951) Reporting OrbiMed Capital GP VIII LLC (1845804) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 07/02/2026 3:45 PM | Sionna Therapeutics (2036042) Issuer Thompson Peter A. (1357522) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/18/2026 4:58 PM | Sionna Therapeutics (2036042) Issuer Stelzer Laurie (1644348) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/18/2026 4:39 PM | Ruddy Marcella K. (2023849) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/18/2026 4:41 PM | Kolchinsky Peter (1384859) Reporting RA Capital Healthcare Fund LP (1315082) Reporting RA CAPITAL MANAGEMENT, L.P. (1346824) Reporting RA Capital Nexus Fund III, L.P. (1883840) Reporting RA Capital Nexus Fund, L.P. (1780117) Reporting Shah Rajeev M. (1619841) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/18/2026 4:45 PM | Sionna Therapeutics (2036042) Issuer Thompson Peter A. (1357522) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/18/2026 4:48 PM | Sionna Therapeutics (2036042) Issuer Viney Joanne L. (1816744) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
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| 06/18/2026 4:29 PM | Booth Bruce (1451612) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/18/2026 4:33 PM | Clancy Paul J (1409601) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/18/2026 4:35 PM | Fleming Harold Edward (1857250) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/18/2026 4:37 PM | Resnick Joshua (1690959) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/18/2026 3:05 PM | Sionna Therapeutics (2036042) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 06/01/2026 11:39 AM | ORBIMED ADVISORS LLC (1055951) Reporting Sionna Therapeutics (2036042) Subject | Form 144/A | |
| 05/29/2026 7:57 PM | ORBIMED ADVISORS LLC (1055951) Reporting OrbiMed Capital GP VIII LLC (1845804) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 05/29/2026 8:02 PM | Sionna Therapeutics (2036042) Issuer Thompson Peter A. (1357522) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 05/29/2026 5:44 PM | ORBIMED ADVISORS LLC (1055951) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 05/15/2026 4:48 PM | Sionna Therapeutics (2036042) Subject VIKING GLOBAL INVESTORS LP (1103804) Filed by | Form SCHEDULE 13G/A | |
| 05/12/2026 6:39 AM | Qatar Investment Authority (1441449) Filed by Sionna Therapeutics (2036042) Subject | Form SCHEDULE 13G/A | |
| 05/12/2026 6:08 AM | Sionna Therapeutics (2036042) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 05/12/2026 6:17 AM | Sionna Therapeutics (2036042) Filer | Form 10-Q General form for quarterly reports under Section 13 or 15(d) | |
| 05/11/2026 6:14 PM | Sionna Therapeutics (2036042) Issuer Thompson Peter A. (1357522) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 05/11/2026 5:58 PM | ORBIMED ADVISORS LLC (1055951) Reporting OrbiMed Capital GP VIII LLC (1845804) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/27/2026 3:13 PM | Sionna Therapeutics (2036042) Filer | Form ARS | |
| 04/21/2026 7:40 PM | ORBIMED ADVISORS LLC (1055951) Reporting OrbiMed Capital GP VIII LLC (1845804) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/21/2026 7:42 PM | Sionna Therapeutics (2036042) Issuer Thompson Peter A. (1357522) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/20/2026 5:46 PM | ORBIMED ADVISORS LLC (1055951) Filed by Sionna Therapeutics (2036042) Subject | Form SCHEDULE 13D/A | |
| 04/16/2026 6:15 PM | Sionna Therapeutics (2036042) Issuer Thompson Peter A. (1357522) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/16/2026 6:03 PM | ORBIMED ADVISORS LLC (1055951) Reporting OrbiMed Capital GP VIII LLC (1845804) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/06/2026 5:56 PM | Fitzpatrick Jennifer (2061851) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/05/2026 3:28 PM | Fitzpatrick Jennifer (2061851) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 03/02/2026 7:18 AM | Sionna Therapeutics (2036042) Filer | Form S-3ASR | |
| 03/02/2026 7:25 AM | Sionna Therapeutics (2036042) Filer | Form S-8 Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans | |
| 03/02/2026 6:19 AM | Sionna Therapeutics (2036042) Filer | Form 10-K Annual report pursuant to Section 13 or 15(d) | |
| 03/02/2026 6:09 AM | Sionna Therapeutics (2036042) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 02/04/2026 6:39 PM | ORBIMED ADVISORS LLC (1055951) Reporting OrbiMed Capital GP VIII LLC (1845804) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/04/2026 6:43 PM | Sionna Therapeutics (2036042) Issuer Thompson Peter A. (1357522) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 01/26/2026 4:24 PM | COULTER JAMES G (1099776) Reporting Sionna Therapeutics (2036042) Issuer TPG GP A, LLC (1903793) Reporting WINKELRIED JON (1366946) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
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| 01/22/2026 7:47 PM | Rise Fund Sling II, L.P. (2103141) Reporting Rise Fund Sling II, L.P. (2103141) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 01/22/2026 7:47 PM | Rise Fund Sling, L.P. (2103170) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 01/06/2026 3:26 PM | McKee Charlotte (2046433) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 12/29/2025 7:42 PM | Sionna Therapeutics (2036042) Issuer Thompson Peter A. (1357522) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 12/29/2025 7:44 PM | ORBIMED ADVISORS LLC (1055951) Reporting OrbiMed Capital GP VIII LLC (1845804) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 12/19/2025 6:24 PM | Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 12/19/2025 6:24 PM | Sionna Therapeutics (2036042) Issuer Thompson Peter A. (1357522) Reporting Thompson Peter A. (1357522) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 12/19/2025 6:29 PM | Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 12/19/2025 6:29 PM | ORBIMED ADVISORS LLC (1055951) Reporting ORBIMED ADVISORS LLC (1055951) Reporting OrbiMed Capital GP VIII LLC (1845804) Reporting OrbiMed Capital GP VIII LLC (1845804) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 12/09/2025 3:57 PM | Fitzpatrick Jennifer (2061851) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 12/05/2025 3:27 PM | Fitzpatrick Jennifer (2061851) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/26/2025 5:41 PM | Sionna Therapeutics (2036042) Issuer Thompson Peter A. (1357522) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 11/26/2025 5:45 PM | ORBIMED ADVISORS LLC (1055951) Reporting OrbiMed Capital GP VIII LLC (1845804) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 11/24/2025 7:22 PM | ORBIMED ADVISORS LLC (1055951) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/24/2025 4:43 PM | Kolchinsky Peter (1384859) Reporting RA Capital Healthcare Fund LP (1315082) Reporting RA CAPITAL MANAGEMENT, L.P. (1346824) Reporting RA Capital Nexus Fund III, L.P. (1883840) Reporting RA Capital Nexus Fund, L.P. (1780117) Reporting Shah Rajeev M. (1619841) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 11/21/2025 3:17 PM | BLACKWELL PARTNERS LLC - SERIES A (1426672) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/21/2025 3:19 PM | RA Capital Nexus Fund, L.P. (1780117) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/21/2025 3:21 PM | RA Capital Nexus Fund III, L.P. (1883840) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/21/2025 3:24 PM | RA Capital Healthcare Fund LP (1315082) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/20/2025 3:30 PM | BLACKWELL PARTNERS LLC - SERIES A (1426672) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/20/2025 3:34 PM | RA Capital Healthcare Fund LP (1315082) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/20/2025 3:35 PM | RA Capital Nexus Fund, L.P. (1780117) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/20/2025 3:40 PM | RA Capital Nexus Fund III, L.P. (1883840) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/19/2025 7:43 PM | Kolchinsky Peter (1384859) Reporting RA Capital Healthcare Fund LP (1315082) Reporting RA CAPITAL MANAGEMENT, L.P. (1346824) Reporting RA Capital Nexus Fund III, L.P. (1883840) Reporting RA Capital Nexus Fund, L.P. (1780117) Reporting Shah Rajeev M. (1619841) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 11/19/2025 4:16 PM | BLACKWELL PARTNERS LLC - SERIES A (1426672) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/19/2025 4:21 PM | RA Capital Healthcare Fund LP (1315082) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/19/2025 4:04 PM | RA Capital Nexus Fund III, L.P. (1883840) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/19/2025 4:10 PM | RA Capital Nexus Fund, L.P. (1780117) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/18/2025 4:22 PM | BLACKWELL PARTNERS LLC - SERIES A (1426672) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/18/2025 4:17 PM | RA Capital Nexus Fund, L.P. (1780117) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/18/2025 4:09 PM | RA Capital Nexus Fund III, L.P. (1883840) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/17/2025 4:12 PM | BLACKWELL PARTNERS LLC - SERIES A (1426672) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/17/2025 3:56 PM | RA Capital Nexus Fund III, L.P. (1883840) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/17/2025 4:04 PM | RA Capital Nexus Fund, L.P. (1780117) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/17/2025 3:46 PM | RA Capital Healthcare Fund LP (1315082) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 11/07/2025 3:59 PM | RA CAPITAL MANAGEMENT, L.P. (1346824) Filed by Sionna Therapeutics (2036042) Subject | Form SCHEDULE 13D/A | |
| 11/05/2025 6:28 AM | Sionna Therapeutics (2036042) Filer | Form 10-Q General form for quarterly reports under Section 13 or 15(d) | |
| 11/05/2025 6:14 AM | Sionna Therapeutics (2036042) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 10/31/2025 8:48 AM | JPMORGAN CHASE & CO (19617) Filed by JPMORGAN CHASE & CO (19617) Filed by JPMORGAN CHASE & CO (19617) Filed by JPMORGAN CHASE & CO (19617) Filed by Sionna Therapeutics (2036042) Subject | Form SCHEDULE 13G/A | |
| 10/28/2025 8:05 PM | Kolchinsky Peter (1384859) Reporting RA Capital Healthcare Fund LP (1315082) Reporting RA CAPITAL MANAGEMENT, L.P. (1346824) Reporting RA Capital Nexus Fund III, L.P. (1883840) Reporting RA Capital Nexus Fund, L.P. (1780117) Reporting Shah Rajeev M. (1619841) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 10/28/2025 4:05 PM | RA Capital Nexus Fund, L.P. (1780117) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/28/2025 4:07 PM | RA Capital Healthcare Fund LP (1315082) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/28/2025 4:13 PM | RA Capital Nexus Fund III, L.P. (1883840) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/24/2025 5:00 PM | RA Capital Nexus Fund III, L.P. (1883840) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/24/2025 5:05 PM | RA Capital Nexus Fund, L.P. (1780117) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/24/2025 4:39 PM | BLACKWELL PARTNERS LLC - SERIES A (1426672) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/24/2025 4:53 PM | RA Capital Healthcare Fund LP (1315082) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/22/2025 4:39 PM | Cloonan Michael (1704336) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 10/21/2025 4:12 PM | Booth Bruce (1451612) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 10/21/2025 3:19 PM | Cloonan Michael (1704336) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
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| 10/21/2025 3:21 PM | Atlas Venture Fund XI, L.P. (1708269) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/21/2025 3:22 PM | Atlas Venture Opportunity Fund II, L.P. (1885327) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/20/2025 8:39 PM | Booth Bruce (1451612) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 10/20/2025 8:40 PM | Atlas Venture Fund XI, L.P. (1708269) Filed by Sionna Therapeutics (2036042) Subject | Form SCHEDULE 13D/A | |
| 10/17/2025 4:11 PM | Cloonan Michael (1704336) Reporting Sionna Therapeutics (2036042) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 10/17/2025 3:27 PM | Atlas Venture Fund XI, L.P. (1708269) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/17/2025 3:27 PM | Atlas Venture Opportunity Fund II, L.P. (1885327) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/16/2025 4:00 PM | Atlas Venture Opportunity Fund II, L.P. (1885327) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |
| 10/16/2025 4:01 PM | Atlas Venture Fund XI, L.P. (1708269) Reporting Sionna Therapeutics (2036042) Subject | Form 144 Notice of proposed sale of securities pursuant to Rule 144 | |