Perceptive Advisors LLC Top Holdings and 13F Report (2026) About Perceptive Advisors LLCInvestment ActivityPerceptive Advisors LLC has $5.11 billion in total holdings as of March 31, 2026.Perceptive Advisors LLC owns shares of 94 different stocks, but just 28 companies or ETFs make up 80% of its holdings.Approximately 15.60% of the portfolio was purchased this quarter.About 29.04% of the portfolio was sold this quarter.This quarter, Perceptive Advisors LLC has purchased 116 new stocks and bought additional shares in 23 stocks.Perceptive Advisors LLC sold shares of 34 stocks and completely divested from 42 stocks this quarter.Largest Holdings PRAXIS PRECISION MEDICINES I $655,974,329Celcuity $356,938,608Ascendis Pharma A/S $350,281,925Roivant Sciences $229,507,270Centessa Pharmaceuticals $208,883,627 Largest New Holdings this Quarter 60770K107 - Moderna $50,800,000 Holding462222100 - Ionis Pharmaceuticals $37,845,360 Holding23954D109 - Day One Biopharmaceuticals $37,644,331 Holding36322Q206 - DAMORA THERAPEUTICS INC $31,675,700 Holding76155X100 - Revolution Medicines $25,148,850 Holding Largest Purchases this Quarter Ascendis Pharma A/S 450,000 shares (about $102.93M)Centessa Pharmaceuticals 2,341,269 shares (about $93.00M)Relay Therapeutics 7,847,896 shares (about $78.09M)Moderna 1,000,000 shares (about $50.80M)BioCryst Pharmaceuticals 4,271,504 shares (about $40.66M) Largest Sales this Quarter APOGEE THERAPEUTICS INC 790,267 shares (about $66.52M)Belite Bio 262,260 shares (about $41.81M)Viridian Therapeutics 1,871,874 shares (about $36.61M)Neurocrine Biosciences 266,000 shares (about $35.04M)SIONNA THERAPEUTICS INC 520,659 shares (about $20.87M) Sector Allocation Over TimeMap of 500 Largest Holdings ofPerceptive Advisors LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorPRAXIS PRECISION MEDICINES I$655,974,329$12,887,600 â–²2.0%2,035,98612.8%COM NEWCELCCelcuity$356,938,608$3,766,620 â–¼-1.0%3,127,2007.0%MedicalASNDAscendis Pharma A/S$350,281,925$102,928,500 â–²41.6%1,531,4216.9%MedicalROIVRoivant Sciences$229,507,270$8,310,000 â–²3.8%8,285,4614.5%MedicalCNTACentessa Pharmaceuticals$208,883,627$92,995,205 â–²80.2%5,258,9034.1%MedicalRYTMRhythm Pharmaceuticals$206,448,951$15,010,674 â–¼-6.8%2,373,7954.0%MedicalSPYRE THERAPEUTICS INC$190,825,869$36,014,160 â–²23.3%3,783,2253.7%COM NEWNUVLNuvalent$161,922,737$8,667,270 â–¼-5.1%1,580,5053.2%MedicalEWTXEdgewise Therapeutics$139,355,181$1,071,000 â–¼-0.8%4,423,9742.7%MedicalPTGXProtagonist Therapeutics$129,734,647$12,600,148 â–¼-8.9%1,230,8792.5%MedicalAPOGEE THERAPEUTICS INC$129,654,121$66,516,773 â–¼-33.9%1,540,3842.5%COMTVTXTravere Therapeutics$123,075,190$4,029,538 â–¼-3.2%4,142,5512.4%MedicalAMLXAmylyx Pharmaceuticals$115,159,8600.0%8,284,8822.3%MedicalIMTXImmatics$102,173,2070.0%10,383,4562.0%MedicalRLAYRelay Therapeutics$97,023,853$78,086,565 â–²412.3%9,751,1411.9%MedicalINHIBRX BIOSCIENCES INC$96,993,192$672,300 â–¼-0.7%1,442,7071.9%COMMGTXMeiraGTx$89,312,8640.0%10,326,1031.7%MedicalZYMEWORKS INC$87,892,353$6,215,629 â–²7.6%3,510,0781.7%COMSLDBSolid Biosciences$85,727,851$526,370 â–²0.6%11,906,6461.7%MedicalDYNE THERAPEUTICS INC$84,646,051$21,572,796 â–²34.2%4,668,8391.7%COMBCRXBioCryst Pharmaceuticals$70,771,994$40,664,718 â–²135.1%7,434,0331.4%MedicalORUKA THERAPEUTICS INC$68,449,324$3,973,050 â–¼-5.5%1,395,5011.3%COMAORTArtivion$59,957,560$3,112,700 â–¼-4.9%1,637,2901.2%MedicalNRIXNurix Therapeutics$57,518,594$2,402,500 â–²4.4%3,710,8771.1%MedicalMRNAModerna$50,800,000$50,800,000 â–²New Holding1,000,0001.0%MedicalNAUTNautilus Biotechnology$48,865,5380.0%12,594,2111.0%MedicalCTMXCytomX Therapeutics$47,464,473$1,967,603 â–²4.3%10,098,8240.9%MedicalALTO NEUROSCIENCE INC$45,182,395$5,069,240 â–²12.6%2,009,8930.9%COM SHSENGENE HOLDINGS INC$39,685,316$283,092 â–¼-0.7%5,827,5060.8%COMIMVTImmunovant$39,678,994$9,874,074 â–¼-19.9%1,597,3830.8%MedicalISRGIntuitive Surgical$39,377,305$1,152,475 â–¼-2.8%85,4190.8%MedicalIONSIonis Pharmaceuticals$37,845,360$37,845,360 â–²New Holding504,0000.7%MedicalDAWNDay One Biopharmaceuticals$37,644,331$37,644,331 â–²New Holding1,755,7990.7%MedicalABIVAX SA$36,621,233$14,415,259 â–¼-28.2%328,8840.7%SPONSORED ADSCRVSCorvus Pharmaceuticals$33,538,412$23,408,000 â–²231.1%2,292,4410.7%MedicalRGENRepligen$33,053,341$4,123,700 â–¼-11.1%280,5410.6%MedicalJAZZJazz Pharmaceuticals$32,138,5000.0%170,0000.6%MedicalDAMORA THERAPEUTICS INC$31,675,700$31,675,700 â–²New Holding1,223,0000.6%COM NEWX4 PHARMACEUTICALS INC$27,826,486$1,747,799 â–²6.7%6,737,6480.5%COM NEWGHGuardant Health$27,711,000$12,931,800 â–²87.5%300,0000.5%MedicalBRIGHT MINDS BIOSCIENCES INC$27,549,386$5,235,306 â–¼-16.0%377,5440.5%COM NEWIVVDInvivyd$27,117,094$1,203,622 â–¼-4.2%20,859,3030.5%MedicalSIONNA THERAPEUTICS INC$26,396,820$20,873,220 â–¼-44.2%658,4390.5%COMAXSMAxsome Therapeutics$25,344,549$177,471 â–²0.7%149,9500.5%MedicalRVMDRevolution Medicines$25,148,850$25,148,850 â–²New Holding258,6000.5%MedicalSAB BIOTHERAPEUTICS INC$24,633,576$21,557,282 â–²700.8%6,431,7430.5%COM NEWBLTEBelite Bio$24,231,532$41,814,735 â–¼-63.3%151,9790.5%MedicalTENAX THERAPEUTICS INC$23,150,034$16,128,153 â–²229.7%1,447,7820.5%COM NEWAXGNAxoGen$23,101,947$2,876,612 â–¼-11.1%697,3120.5%MedicalVRDNViridian Therapeutics$22,901,415$36,613,855 â–¼-61.5%1,170,8290.4%MedicalOBIOOrchestra BioMed$21,411,101$379,738 â–¼-1.7%5,037,9060.4%MedicalRAPPORT THERAPEUTICS INC$21,087,0510.0%673,9230.4%COMDBV TECHNOLOGIES S A$20,146,128$20,146,128 â–²New Holding964,3910.4%SPONSORED ADSLEONABIO INC$19,113,8300.0%1,859,3220.4%COMANTERIS TECHNOLOGIES GLOBAL$19,011,392$9,712,500 â–²104.4%3,425,4760.4%COMSUTRO BIOPHARMA INC$17,818,297$17,818,297 â–²New Holding715,3070.3%COM SHSTNGXTango Therapeutics$16,906,561$6,173,869 â–²57.5%808,1530.3%MedicalCONTINEUM THERAPEUTICS INC$16,398,032$2,729,540 â–¼-14.3%1,255,5920.3%CL ACELCUITY INC$15,875,7740.0%6,500,0000.3%NOTE 2.750% 8/0PALISADE BIO INC$15,624,261$5,463,239 â–¼-25.9%8,928,1490.3%COMOCSOculis$13,130,8600.0%493,8270.3%MedicalIRTCiRhythm Technologies$12,395,169$350,991 â–¼-2.8%105,0260.2%MedicalEVOMMUNE INC$10,307,567$10,307,567 â–²New Holding448,3500.2%COM SHSPHATPhathom Pharmaceuticals$10,276,750$10,276,750 â–²New Holding925,0000.2%MedicalNEUMORA THERAPEUTICS INC.$9,952,989$9,952,989 â–²New Holding5,104,0970.2%COMOMADA HEALTH INC$9,884,168$20,237,700 â–¼-67.2%786,3300.2%COMNBIXNeurocrine Biosciences$8,569,687$35,042,840 â–¼-80.4%65,0500.2%MedicalBETA BIONICS INC$8,446,299$2,404,800 â–²39.8%842,9440.2%COMOPUS GENETICS INC$8,353,081$11,325,669 â–¼-57.6%1,835,8420.2%COMBILLIONTOONE INC$7,247,639$1,499,860 â–²26.1%91,8120.1%CL ATWSTTwist Bioscience$7,128,000$7,128,000 â–²New Holding150,0000.1%MedicalSURROZEN INC$6,682,218$6,682,218 â–²New Holding229,3930.1%COM NEWAGOMAB THERAPEUTICS NV$6,294,000$6,294,000 â–²New Holding600,0000.1%SPONSORED ADSEOLSEvolus$5,289,003$5,289,003 â–²New Holding1,286,8620.1%MedicalCOGTCogent Biosciences$4,660,4460.0%121,0820.1%MedicalADAGIO MED HLDGS INC$4,347,955$7,010,109 â–¼-61.7%3,780,8300.1%COMOCULOcular Therapeutix$4,235,000$4,235,000 â–²New Holding500,0000.1%MedicalADMAADMA Biologics$4,209,769$3,750,277 â–¼-47.1%467,2330.1%MedicalINHIBIKASE THERAPEUTICS INC$3,889,200$5,219,034 â–¼-57.3%2,315,0000.1%COM NEWCRESCENT BIOPHARMA INC.$3,801,525$4,532,688 â–¼-54.4%206,9420.1%COMAPLSApellis Pharmaceuticals$3,256,860$3,256,860 â–²New Holding80,9560.1%MedicalOUTSET MED INC$3,199,9980.0%833,3330.1%COM NEWEDESA BIOTECH INC$2,945,740$2,945,740 â–²New Holding563,2390.1%COM NEWADPTAdaptive Biotechnologies$2,116,700$2,116,700 â–²New Holding152,5000.0%MedicalAVALO THERAPEUTICS INC$2,085,2280.0%139,6670.0%COM NEWCONNECT BIOPHARMA HLDGS LTD$2,076,8640.0%792,6960.0%SHSCORTCorcept Therapeutics$2,015,500$2,015,500 â–²New Holding50,0000.0%MedicalMEDLINE INC$1,246,0000.0%28,0000.0%COM CL APALATIN TECHNOLOGIES INC$1,079,082$140,318 â–¼-11.5%61,9450.0%COM NEWCPIXCumberland Pharmaceuticals$640,179$468,355 â–¼-42.2%196,9780.0%MedicalREVOLUTION MEDICINES INC$447,5000.0%250,0000.0%*W EXP 12/17/202XGNExagen$344,679$344,679 â–²New Holding114,8930.0%MedicalENSYSCE BIOSCIENCES INC$46,6700.0%86,6660.0%COM NEWSRZNWSurrozen$2,6670.0%166,6660.0%MedicalXBISPDR S&P Biotech ETF$0$134,123,000 â–¼-100.0%00.0%ETFEXASExact Sciences$0$121,921,460 â–¼-100.0%00.0%MedicalACLXArcellx$0$95,587,829 â–¼-100.0%00.0%MedicalBSXBoston Scientific$0$93,347,650 â–¼-100.0%00.0%MedicalFOLDAmicus Therapeutics$0$90,720,918 â–¼-100.0%00.0%MedicalATXSAstria Therapeutics$0$84,894,147 â–¼-100.0%00.0%MedicalShowing largest 100 holdings. 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