NYSEARCA:XBI SPDR S&P Biotech ETF (XBI) Price, Holdings, & News $156.86 -2.53 (-1.59%) As of 08/13/2026 04:10 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartDividendHeadlinesHoldingsOwnershipRatingsShort InterestBuy This Stock About SPDR S&P Biotech ETF (NYSEARCA:XBI) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SPDR S&P Biotech ETF alerts:Sign Up Key Stats Today's Range$156.55▼$160.6750-Day Range$128.43▼$164.2852-Week Range$88.18▼$165.71Volume7.52 million shsAverage Volume9.18 million shsMarket Capitalization$10.24 billionAssets Under Management$10.77 billionDividend Yield0.36%Net Expense Ratio0.35%Aggregate RatingModerate Buy ETF Overview SPDR S&P Biotech ETF (the Fund) seeks to closely match the returns and characteristics of the S&P Biotechnology Select Industry Index. The S&P Biotechnology Select Industry Index represents the biotechnology sub-industry portion of the S&P Total Markets Index. The S&P TMI tracks all the United States common stocks listed on the New York Stock Exchange, American Stock Exchange, National Association of Securities Dealers Automated Quotation (NASDAQ) National Market and NASDAQ Small Cap exchanges. The Biotech Index is a modified equal weight index. SSgA Funds Management, Inc. is the Fund's investment advisor. Read More SPDR S&P Biotech ETF ExpensesTypeXBIHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.35%0.55%0.57%0.51%0.53%Other Expenses0.00%0.52%0.53%0.60%0.54%Total Expense0.35%0.76%0.75%0.75%0.73%Fee Waiver0.00%-0.85%-0.67%-0.77%-0.68%Net Expense0.35%0.58%0.63%0.57%0.60% Receive XBI Stock News and Ratings via Email Sign-up to receive the latest news and ratings for SPDR S&P Biotech ETF and its competitors with MarketBeat's FREE daily newsletter. 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XBI ETF News HeadlinesiShares Global Healthcare ETF vs State Street SPDR Biotech ETF. Which Healthcare-Focused Fund Will Bring You Profits in 2026 and Beyond?August 8, 2026 | fool.comThese New Drugs Could Fuel Fresh Highs for Biotech and Pharma StocksAugust 7, 2026 | barrons.comMan who Predicted Trump 2016 Win: “Prepare for Mid-Term Meltdown”In 2016, major election models gave Hillary Clinton a 99% chance of winning - but former CIA and Pentagon adviser Jim Rickards publicly predicted a Trump victory before election night. Now Rickards is issuing a new forecast he calls a potential mid-term meltdown, one he believes could send shockwaves through financial markets.August 14 at 1:00 AM | Paradigm Press (Ad)ETF Showdown: XBI vs PBE, Which Biotech Fund Wins?July 24, 2026 | 247wallst.comBiotech remains compelling even after major comeback. Here’s what investors sayJuly 22, 2026 | cnbc.comBuying Biotech's Policy Discount With XBI And IBB: Most 'Feared' Nation Policy, Less-Than-Feared DamageJuly 21, 2026 | seekingalpha.comSee More Headlines XBI ETF - Frequently Asked Questions How have XBI shares performed this year? SPDR S&P Biotech ETF's stock was trading at $121.93 at the start of the year. Since then, XBI stock has increased by 28.6% and is now trading at $156.86. Who are SPDR S&P Biotech ETF's major shareholders? SPDR S&P Biotech ETF's top institutional investors include Annex Advisory Services LLC (0.37%), Polymer Capital Management HK LTD (0.16%), S&CO Inc. (0.14%) and Crescent Grove Advisors LLC (0.10%). How do I buy shares of SPDR S&P Biotech ETF? Shares of XBI stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of SPDR S&P Biotech ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that SPDR S&P Biotech ETF investors own include American Water Works (AWK), Waste Connections (WCN), The RMR Group (RMR), iShares Micro-Cap ETF (IWC), Voyager Therapeutics (VYGR), DiamondRock Hospitality (DRH) and Humana (HUM). Fund Details IssuerSSgA Fund NameSPDR S&P Biotech ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:XBI Inception Date1/31/2006 Fund ManagerMichael Feehily, Karl Schneider, Raymond Donofrio Webwww.spdrs.com Phone+1-866-7872257Fund Focus Asset ClassEquity BenchmarkS&P Biotechnology Select Industry Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings165 Fund Statistics Assets Under Management$10.77 billion Average Daily Volume$8.04 million Discount/Premium0.05% Administrator, Advisor and Custodian AdministratorState Street Global Advisors Funds Management, Inc. AdvisorSSgA Funds Management, Inc. CustodianState Street Bank and Trust Company DistributorState Street Global Advisors Funds Distributors, LLC Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerVirtu Financial Options OptionableOptionable Options Volume14,338 Put Options6,702 Call Options7,636 Short Interest78,847,922 shs Miscellaneous Outstanding Shares65,300,000Beta0.83 Creation Unit50,000 Creation Fee$250.00 7 Stocks That Will Be Magnificent in 2026Discover the next wave of investment opportunities with our report, 7 Stocks That Will Be Magnificent in 2026. Explore companies poised to replicate the growth, innovation, and value creation of the tech giants dominating today's markets.Get This Free Report Top 10 XBI HoldingsApogee Therapeutics (NASDAQ:APGE)Holding Weight: 1.65%Oruka Therapeutics (NASDAQ:ORKA)Holding Weight: 1.53%Dianthus Therapeutics (NASDAQ:DNTH)Holding Weight: 1.42%Erasca (NASDAQ:ERAS)Holding Weight: 1.38%Twist Bioscience (NASDAQ:TWST)Holding Weight: 1.37%Kymera Therapeutics (NASDAQ:KYMR)Holding Weight: 1.34%Spyre Therapeutics (NASDAQ:SYRE)Holding Weight: 1.33%CG Oncology (NASDAQ:CGON)Holding Weight: 1.32%Revolution Medicines (NASDAQ:RVMD)Holding Weight: 1.32%Protagonist Therapeutics (NASDAQ:PTGX)Holding Weight: 1.31%Full Holdings DetailsXBI Sector ExposureXBI Industry Exposure This page (NYSEARCA:XBI) was last updated on 8/14/2026 by MarketBeat.com Staff. From Our PartnersTrump’s New Currency ResetTrump is launching a new $250 bill - but that may be a distraction. 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