NYSEARCA:XBI SPDR S&P Biotech ETF (XBI) Price, Holdings, & News $163.81 -0.57 (-0.35%) As of 09/4/2026 04:10 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartDividendHoldingsNews and TrendsOwnershipRatingsShort Interest About SPDR S&P Biotech ETF (NYSEARCA:XBI) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SPDR S&P Biotech ETF alerts:Sign Up Key Stats Today's Range$162.51▼$164.3550-Day Range$147.01▼$169.5552-Week Range$92.64▼$169.89Volume3.80 million shsAverage Volume9.11 million shsMarket Capitalization$10.70 billionAssets Under Management$11.47 billionDividend Yield0.35%Net Expense Ratio0.35%Aggregate RatingModerate Buy ETF Overview SPDR S&P Biotech ETF (the Fund) seeks to closely match the returns and characteristics of the S&P Biotechnology Select Industry Index. The S&P Biotechnology Select Industry Index represents the biotechnology sub-industry portion of the S&P Total Markets Index. The S&P TMI tracks all the United States common stocks listed on the New York Stock Exchange, American Stock Exchange, National Association of Securities Dealers Automated Quotation (NASDAQ) National Market and NASDAQ Small Cap exchanges. The Biotech Index is a modified equal weight index. SSgA Funds Management, Inc. is the Fund's investment advisor. Read More SPDR S&P Biotech ETF ExpensesTypeXBIHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.35%0.55%0.57%0.50%0.53%Other Expenses0.00%0.52%0.53%0.60%0.54%Total Expense0.35%0.76%0.75%0.75%0.73%Fee Waiver0.00%-0.85%-0.67%-0.78%-0.68%Net Expense0.35%0.58%0.63%0.57%0.60% Receive XBI Stock News and Ratings via Email Sign-up to receive the latest news and ratings for SPDR S&P Biotech ETF and its competitors with MarketBeat's FREE daily newsletter. 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XBI ETF News HeadlinesAfter-hours Gainers: HOWL Jumps 90%, MODD To Begin Pivot Pump Rollout, BIVI Awaits Long COVID Data August 20, 2026 | rttnews.comXBI: Biotech's Breakthrough Moment Happend This Week (Upgrade)August 20, 2026 | seekingalpha.comLouis Navellier: My #1 AI stock for 2026 (name & ticker inside)Louis Navellier's Stock Grader system helped him flag Nvidia before its 82,000% run and has identified the top S&P 500 stock for 12 years running—and today, he's giving away his #1 AI stock pick for 2026, free. This company's sales are up 28% year over year, it holds over 30,000 patents in wireless and video technology, and it just earned an A-rating in his proprietary Stock Grader system that has cost him $9 million to build and maintain.September 5 at 1:00 AM | InvestorPlace (Ad)XBI vs. FBT: Broad Biotech Exposure or Concentrated Bets?August 19, 2026 | finance.yahoo.comWhich Healthcare ETF Is the Better Buy: VanEck's Pharma PPH or State Street's Biotech XBI?August 18, 2026 | finance.yahoo.comiShares Global Healthcare ETF vs State Street SPDR Biotech ETF. Which Healthcare-Focused Fund Will Bring You Profits in 2026 and Beyond?August 8, 2026 | fool.comSee More Headlines XBI ETF - Frequently Asked Questions How have XBI shares performed this year? SPDR S&P Biotech ETF's stock was trading at $121.93 at the beginning of 2026. Since then, XBI shares have increased by 34.3% and is now trading at $163.81. Who are SPDR S&P Biotech ETF's major shareholders? Top institutional investors of SPDR S&P Biotech ETF include Northwestern Mutual Wealth Management Co. (0.48%), Annex Advisory Services LLC (0.37%), Wellington Management Group LLP (0.19%) and Polymer Capital Management HK LTD (0.16%). How do I buy shares of SPDR S&P Biotech ETF? Shares of XBI stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of SPDR S&P Biotech ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that SPDR S&P Biotech ETF investors own include American Water Works (AWK), Waste Connections (WCN), The RMR Group (RMR), iShares Micro-Cap ETF (IWC), Voyager Therapeutics (VYGR), DiamondRock Hospitality (DRH) and Humana (HUM). Fund Details IssuerSSgA Fund NameSPDR S&P Biotech ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:XBI Inception Date1/31/2006 Fund ManagerMichael Feehily, Karl Schneider, Raymond Donofrio Webwww.spdrs.com Phone+1-866-7872257Fund Focus Asset ClassEquity BenchmarkS&P Biotechnology Select Industry Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings165 Fund Statistics Assets Under Management$11.47 billion Average Daily Volume$8.13 million Discount/Premium-0.07% Administrator, Advisor and Custodian AdministratorState Street Global Advisors Funds Management, Inc. AdvisorSSgA Funds Management, Inc. CustodianState Street Bank and Trust Company DistributorState Street Global Advisors Funds Distributors, LLC Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerVirtu Financial Options OptionableOptionable Options Volume19,684 Put Options9,356 Call Options10,328 Short Interest77,134,345 shs Miscellaneous Outstanding Shares65,300,000Beta0.84 Creation Unit50,000 Creation Fee$250.00 7 Stocks to Buy Before the Robotics RevolutionRobotics and automation are rapidly becoming essential infrastructure across healthcare, manufacturing, logistics, and many other industries. "Physical AI" is coming. Learn which seven companies are most positioned to benefit as intelligent robots enter the workforce.Get This Free Report Top 10 XBI HoldingsTwist Bioscience (NASDAQ:TWST)Holding Weight: 1.76%Oruka Therapeutics (NASDAQ:ORKA)Holding Weight: 1.61%Apogee Therapeutics (NASDAQ:APGE)Holding Weight: 1.55%Praxis Precision Medicines (NASDAQ:PRAX)Holding Weight: 1.46%Kymera Therapeutics (NASDAQ:KYMR)Holding Weight: 1.39%Dianthus Therapeutics (NASDAQ:DNTH)Holding Weight: 1.37%Natera (NASDAQ:NTRA)Holding Weight: 1.37%Halozyme Therapeutics (NASDAQ:HALO)Holding Weight: 1.36%Protagonist Therapeutics (NASDAQ:PTGX)Holding Weight: 1.36%Revolution Medicines (NASDAQ:RVMD)Holding Weight: 1.33%Full Holdings DetailsXBI Sector ExposureXBI Industry Exposure This page (NYSEARCA:XBI) was last updated on 9/5/2026 by MarketBeat.com Staff. 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