NYSEARCA:XBI SPDR S&P Biotech ETF (XBI) Price, Holdings, & News $131.66 0.00 (0.00%) As of 05/22/2026 04:10 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartDividendHeadlinesHoldingsOwnershipRatingsShort InterestBuy This Stock About SPDR S&P Biotech ETF (NYSEARCA:XBI) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SPDR S&P Biotech ETF alerts:Sign Up Key Stats Today's Range$131.47▼$134.2950-Day Range$118.78▼$138.6752-Week Range$78.00▼$139.19Volume6.47 million shsAverage Volume9.33 million shsMarket Capitalization$8.40 billionAssets Under Management$8.22 billionDividend Yield0.33%Net Expense Ratio0.35%Aggregate RatingModerate Buy ETF Overview SPDR S&P Biotech ETF (the Fund) seeks to closely match the returns and characteristics of the S&P Biotechnology Select Industry Index. The S&P Biotechnology Select Industry Index represents the biotechnology sub-industry portion of the S&P Total Markets Index. The S&P TMI tracks all the United States common stocks listed on the New York Stock Exchange, American Stock Exchange, National Association of Securities Dealers Automated Quotation (NASDAQ) National Market and NASDAQ Small Cap exchanges. The Biotech Index is a modified equal weight index. SSgA Funds Management, Inc. is the Fund's investment advisor. Read More SPDR S&P Biotech ETF ExpensesTypeXBIHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.35%0.56%0.57%0.51%0.53%Other Expenses0.00%0.47%0.55%0.58%0.55%Total Expense0.35%0.74%0.76%0.74%0.73%Fee Waiver0.00%-0.71%-0.64%-0.70%-0.62%Net Expense0.35%0.59%0.63%0.58%0.60% Receive XBI Stock News and Ratings via Email Sign-up to receive the latest news and ratings for SPDR S&P Biotech ETF and its competitors with MarketBeat's FREE daily newsletter. 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XBI ETF News HeadlinesBiotech Investors Are Tuning Out the MAHA ChaosMay 20, 2026 | wsj.comTrade Tracker: Joe Terranova sells the biotech ETF XBIMay 19, 2026 | msn.comI was right about SpaceXJeff Brown predicted Bitcoin before it climbed as high as 52,400%, Tesla before 2,150%, and Nvidia before 32,000%. Now he says SpaceX is shaping up to be the biggest IPO of the decade - and three key milestones just confirmed it. In the past 21 days: SpaceX crossed 10,000 active satellites, Elon filed confidential IPO paperwork with the SEC, and another rocket launched 25 more satellites. Two-thirds of every satellite in orbit now belongs to one company. The public filing could drop any day.May 25 at 1:00 AM | Brownstone Research (Ad)If You Hold This Healthcare ETF, You're Losing BigMay 19, 2026 | 247wallst.com2 Ways to Play the Big Pharma Patent CliffWith hundreds of billions in sales on the line for drugs that will lose their patent exclusivity in the coming years, two biotech ETFs can help capitalize.May 14, 2026 | marketbeat.comWhy this biotech ETF — the IBD stock of the day — just reentered its buy zoneMay 4, 2026 | msn.comSee More Headlines XBI ETF - Frequently Asked Questions How have XBI shares performed this year? SPDR S&P Biotech ETF's stock was trading at $121.93 at the beginning of the year. Since then, XBI stock has increased by 8.0% and is now trading at $131.66. Who are SPDR S&P Biotech ETF's major shareholders? Top institutional shareholders of SPDR S&P Biotech ETF include Bank of America Corp DE (22.76%), Healthcare of Ontario Pension Plan Trust Fund (15.28%), Bessemer Group Inc. (2.83%) and Meitav Investment House Ltd. (1.27%). How do I buy shares of SPDR S&P Biotech ETF? Shares of XBI stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of SPDR S&P Biotech ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that SPDR S&P Biotech ETF investors own include American Water Works (AWK), Waste Connections (WCN), The RMR Group (RMR), iShares Micro-Cap ETF (IWC), Voyager Therapeutics (VYGR), DiamondRock Hospitality (DRH) and Humana (HUM). Fund Details IssuerSSgA Fund NameSPDR S&P Biotech ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:XBI Inception Date1/31/2006 Fund ManagerMichael Feehily, Karl Schneider, Raymond Donofrio Webwww.spdrs.com Phone+1-866-7872257Fund Focus Asset ClassEquity BenchmarkS&P Biotechnology Select Industry Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings161 Fund Statistics Assets Under Management$8.22 billion Average Daily Volume$8.18 million Discount/Premium-0.05% Administrator, Advisor and Custodian AdministratorState Street Global Advisors Funds Management, Inc. AdvisorSSgA Funds Management, Inc. CustodianState Street Bank and Trust Company DistributorState Street Global Advisors Funds Distributors, LLC Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerVirtu Financial Options OptionableOptionable Options Volume15,381 Put Options8,619 Call Options6,762 Short Interest74,760,000 shs Miscellaneous Outstanding Shares63,800,000Beta0.85 Creation Unit50,000 Creation Fee$250.00 Beginner's Guide To Retirement StocksClick the link to see MarketBeat's list of seven best retirement stocks and why they should be in your portfolio. Get This Free Report Top 10 XBI HoldingsTG Therapeutics (NASDAQ:TGTX)Holding Weight: 1.70%Revolution Medicines (NASDAQ:RVMD)Holding Weight: 1.68%Travere Therapeutics (NASDAQ:TVTX)Holding Weight: 1.68%Alkermes (NASDAQ:ALKS)Holding Weight: 1.57%Arrowhead Pharmaceuticals (NASDAQ:ARWR)Holding Weight: 1.50%Neurocrine Biosciences (NASDAQ:NBIX)Holding Weight: 1.39%Beam Therapeutics (NASDAQ:BEAM)Holding Weight: 1.37%Exelixis (NASDAQ:EXEL)Holding Weight: 1.37%Krystal Biotech (NASDAQ:KRYS)Holding Weight: 1.37%Cytokinetics (NASDAQ:CYTK)Holding Weight: 1.36%Full Holdings DetailsXBI Sector ExposureXBI Industry Exposure This page (NYSEARCA:XBI) was last updated on 5/25/2026 by MarketBeat.com Staff. 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