NYSEARCA:XBI SPDR S&P Biotech ETF (XBI) Price, Holdings, & News $133.03 -0.47 (-0.35%) As of 02:29 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartDividendHeadlinesHoldingsOwnershipRatingsShort InterestBuy This Stock About SPDR S&P Biotech ETF (NYSEARCA:XBI) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SPDR S&P Biotech ETF alerts:Sign Up Key Stats Today's Range$131.96▼$136.3750-Day Range$118.78▼$138.6752-Week Range$75.68▼$139.19Volume6.33 million shsAverage Volume9.40 million shsMarket Capitalization$8.49 billionAssets Under Management$8.23 billionDividend Yield0.33%Net Expense Ratio0.35%Aggregate RatingModerate Buy ETF Overview SPDR S&P Biotech ETF (the Fund) seeks to closely match the returns and characteristics of the S&P Biotechnology Select Industry Index. The S&P Biotechnology Select Industry Index represents the biotechnology sub-industry portion of the S&P Total Markets Index. The S&P TMI tracks all the United States common stocks listed on the New York Stock Exchange, American Stock Exchange, National Association of Securities Dealers Automated Quotation (NASDAQ) National Market and NASDAQ Small Cap exchanges. The Biotech Index is a modified equal weight index. SSgA Funds Management, Inc. is the Fund's investment advisor. Read More SPDR S&P Biotech ETF ExpensesTypeXBIHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.35%0.56%0.57%0.51%0.53%Other Expenses0.00%0.47%0.55%0.58%0.55%Total Expense0.35%0.74%0.76%0.74%0.73%Fee Waiver0.00%-0.71%-0.64%-0.70%-0.61%Net Expense0.35%0.59%0.63%0.58%0.60% Receive XBI Stock News and Ratings via Email Sign-up to receive the latest news and ratings for SPDR S&P Biotech ETF and its competitors with MarketBeat's FREE daily newsletter. 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XBI ETF News HeadlinesWhy this biotech ETF — the IBD stock of the day — just reentered its buy zoneMay 4 at 5:35 PM | msn.comLocking in a quick gain in this biotech ETF made room for better swing trades; here's whyMay 1, 2026 | msn.comYour book is insideThe "Sucker's Bet" Most New Options Traders Fall For Most people who try options lose money the same way. They don't know the rules. They don't know what to avoid. And they hand their account to Wall Street on a silver platter. Normally $29.97. Free today.May 5 at 1:00 AM | Profits Run (Ad)Equal-Weight ETFs Are the Play for Small-Cap Drug Development. Here's How to Position NowApril 23, 2026 | 247wallst.comXBI vs. IBB: The Biotech ETF Showdown That Analysts Say Has a Clear Winner in 2026April 7, 2026 | 247wallst.comThis Biotech ETF Is Still Well Below Its 2021 Peak. Analysts Say That Is Exactly Why to Buy It.April 3, 2026 | 247wallst.comSee More Headlines XBI ETF - Frequently Asked Questions How have XBI shares performed this year? SPDR S&P Biotech ETF's stock was trading at $121.93 at the beginning of 2026. Since then, XBI shares have increased by 9.9% and is now trading at $134.00. Who are SPDR S&P Biotech ETF's major shareholders? SPDR S&P Biotech ETF's top institutional shareholders include Meitav Investment House Ltd. (1.27%), Main Street Research LLC (0.89%), Strs Ohio (0.63%) and SG Americas Securities LLC (0.61%). How do I buy shares of SPDR S&P Biotech ETF? Shares of XBI stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of SPDR S&P Biotech ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that SPDR S&P Biotech ETF investors own include American Water Works (AWK), Waste Connections (WCN), The RMR Group (RMR), iShares Micro-Cap ETF (IWC), Voyager Therapeutics (VYGR), DiamondRock Hospitality (DRH) and Humana (HUM). Fund Details IssuerSSgA Fund NameSPDR S&P Biotech ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:XBI Inception Date1/31/2006 Fund ManagerMichael Feehily, Karl Schneider, Raymond Donofrio Webwww.spdrs.com Phone+1-866-7872257Fund Focus Asset ClassEquity BenchmarkS&P Biotechnology Select Industry Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings156 Fund Statistics Assets Under Management$8.23 billion Average Daily Volume$7.75 million Discount/Premium-0.06% Administrator, Advisor and Custodian AdministratorState Street Global Advisors Funds Management, Inc. AdvisorSSgA Funds Management, Inc. CustodianState Street Bank and Trust Company DistributorState Street Global Advisors Funds Distributors, LLC Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerVirtu Financial Options OptionableOptionable Options Volume22,349 Put Options9,878 Call Options12,471 Short Interest73,330,000 shs Miscellaneous Outstanding Shares63,800,000Beta0.85 Creation Unit50,000 Creation Fee$250.00 Analysts Agree—These Gold Picks Outshine the RestUnlock the timeless value of gold with our exclusive 2026 Gold Forecasting Report. Explore why gold remains the ultimate investment for safeguarding wealth against inflation, economic shifts, and global uncertainties. Whether you're planning for future generations or seeking a reliable asset in turbulent times, this report is your essential guide to making informed decisions.Get This Free Report Top 10 XBI HoldingsApellis Pharmaceuticals (NASDAQ:APLS)Holding Weight: 1.87%Revolution Medicines (NASDAQ:RVMD)Holding Weight: 1.65%Travere Therapeutics (NASDAQ:TVTX)Holding Weight: 1.62%Arrowhead Pharmaceuticals (NASDAQ:ARWR)Holding Weight: 1.44%Twist Bioscience (NASDAQ:TWST)Holding Weight: 1.42%Summit Therapeutics (NASDAQ:SMMT)Holding Weight: 1.40%Alkermes (NASDAQ:ALKS)Holding Weight: 1.38%TG Therapeutics (NASDAQ:TGTX)Holding Weight: 1.37%Madrigal Pharmaceuticals (NASDAQ:MDGL)Holding Weight: 1.36%Beam Therapeutics (NASDAQ:BEAM)Holding Weight: 1.32%Full Holdings DetailsXBI Sector ExposureXBI Industry Exposure This page (NYSEARCA:XBI) was last updated on 5/5/2026 by MarketBeat.com Staff. 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