NYSEARCA:XBI SPDR S&P Biotech ETF (XBI) Price, Holdings, & News $149.78 +3.01 (+2.05%) Closing price 04:10 PM EasternExtended Trading$149.73 -0.05 (-0.03%) As of 04:48 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisChartDividendHoldingsNews and TrendsOwnershipRatingsShort Interest About SPDR S&P Biotech ETF (NYSEARCA:XBI) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SPDR S&P Biotech ETF alerts:Sign Up Key Stats Today's Range$146.93▼$150.8650-Day Range$146.77▼$169.5552-Week Range$106.30▼$169.89Volume11.45 million shsAverage Volume9.17 million shsMarket Capitalization$10.04 billionAssets Under Management$10.14 billionDividend Yield0.36%Net Expense Ratio0.35%Aggregate RatingModerate Buy ETF Overview SPDR S&P Biotech ETF (the Fund) seeks to closely match the returns and characteristics of the S&P Biotechnology Select Industry Index. The S&P Biotechnology Select Industry Index represents the biotechnology sub-industry portion of the S&P Total Markets Index. The S&P TMI tracks all the United States common stocks listed on the New York Stock Exchange, American Stock Exchange, National Association of Securities Dealers Automated Quotation (NASDAQ) National Market and NASDAQ Small Cap exchanges. The Biotech Index is a modified equal weight index. SSgA Funds Management, Inc. is the Fund's investment advisor. Read More SPDR S&P Biotech ETF ExpensesTypeXBIHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.35%0.55%0.57%0.50%0.53%Other Expenses0.00%0.52%0.53%0.60%0.54%Total Expense0.35%0.76%0.75%0.75%0.73%Fee Waiver0.00%-0.85%-0.67%-0.78%-0.68%Net Expense0.35%0.58%0.63%0.57%0.60% Receive XBI Stock News and Ratings via Email Sign-up to receive the latest news and ratings for SPDR S&P Biotech ETF and its competitors with MarketBeat's FREE daily newsletter. 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XBI ETF News HeadlinesBetter State Street Healthcare ETF: XBI's Biotech Focus vs. XPH Targeting PharmaceuticalsOctober 3, 2026 | fool.comBiotech lagged the broader market in September — did retail favorites SLS, IBRX, VNDA and IOVA dodge XBI’s slump?September 30, 2026 | msn.comIran War Shock: What I Was Told In That Private MeetingYou’re Being LIED To About The Iran War Forget EVERYTHING you’ve heard about the Iran war. Especially the reasons why we’re bombing the country.October 15 at 1:00 AM | Banyan Hill Publishing (Ad)SPDR S&P Biotech (XBI)September 29, 2026 | es.investing.comBiotech week ahead: XLV beats the market — here are the stocks, readouts and events to watch nextSeptember 21, 2026 | msn.comBiotech midweek pulse: XBI loses steam after hot 2026 run — here are the stocks and catalysts to watch nextSeptember 15, 2026 | msn.comSee More Headlines XBI ETF - Frequently Asked Questions How have XBI shares performed this year? SPDR S&P Biotech ETF's stock was trading at $121.93 at the beginning of the year. Since then, XBI stock has increased by 22.8% and is now trading at $149.78. Who are SPDR S&P Biotech ETF's major shareholders? SPDR S&P Biotech ETF's top institutional investors include Sivik Global Healthcare LLC (0.27%), Edge Wealth Management LLC (0.17%), Lake Hills Wealth Management LLC (0.16%) and Ayalon Insurance Comp Ltd. (0.15%). How do I buy shares of SPDR S&P Biotech ETF? Shares of XBI stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of SPDR S&P Biotech ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that SPDR S&P Biotech ETF investors own include NVIDIA (NVDA), Advanced Micro Devices (AMD), Tesla (TSLA), Micron Technology (MU), Invesco QQQ (QQQ), PayPal (PYPL) and SPDR S&P 500 ETF Trust (SPY). Fund Details IssuerSSgA Fund NameSPDR S&P Biotech ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:XBI Inception Date1/31/2006 Fund ManagerMichael Feehily, Karl Schneider, Raymond Donofrio Webwww.spdrs.com Phone+1-866-7872257Fund Focus Asset ClassEquity BenchmarkS&P Biotechnology Select Industry Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings173 Fund Statistics Assets Under Management$10.14 billion Average Daily Volume$9.77 million Discount/Premium0.04% Administrator, Advisor and Custodian AdministratorState Street Global Advisors Funds Management, Inc. AdvisorSSgA Funds Management, Inc. CustodianState Street Bank and Trust Company DistributorState Street Global Advisors Funds Distributors, LLC Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerVirtu Financial Options OptionableOptionable Options Volume28,287 Put Options20,102 Call Options8,185 Short Interest74,208,736 shs Miscellaneous Outstanding Shares67,030,000Beta0.83 Creation Unit50,000 Creation Fee$250.00 The 10 Best High-Yield Dividend Stocks for 2026Discover the 10 Best High-Yield Dividend Stocks for 2026 and secure reliable income in uncertain markets. Download the report now to identify top dividend payers and avoid common yield traps.Get This Free Report Top 10 XBI HoldingsTwist Bioscience (NASDAQ:TWST)Holding Weight: 2.37%Moderna (NASDAQ:MRNA)Holding Weight: 2.17%Natera (NASDAQ:NTRA)Holding Weight: 1.87%Iovance Biotherapeutics (NASDAQ:IOVA)Holding Weight: 1.56%Spyre Therapeutics (NASDAQ:SYRE)Holding Weight: 1.55%AbbVie (NYSE:ABBV)Holding Weight: 1.54%Biogen (NASDAQ:BIIB)Holding Weight: 1.54%United Therapeutics (NASDAQ:UTHR)Holding Weight: 1.54%CRISPR Therapeutics (NASDAQ:CRSP)Holding Weight: 1.53%Amgen (NASDAQ:AMGN)Holding Weight: 1.49%Full Holdings DetailsXBI Sector ExposureXBI Industry Exposure This page (NYSEARCA:XBI) was last updated on 10/15/2026 by MarketBeat.com Staff. 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