SPDR S&P Biotech ETF Rating $154.18 +0.15 (+0.10%) Closing price 09/16/2026 04:10 PM EasternExtended Trading$154.40 +0.22 (+0.14%) As of 09/16/2026 07:53 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Ratings Stock AnalysisChartDividendHoldingsNews and TrendsOwnershipRatingsShort Interest SPDR S&P Biotech ETF Aggregate Rating and Price Target (2026)How MarketBeat Aggregates ETF Rating and Price TargetMarketBeat calculates the aggregate rating and price target for an ETF by considering the weight of each stock in its portfolio. These ratings and price targets are based on the most recent ratings given by Wall Street analysts over the past year. The aggregate rating reviews the ETF's overall performance and is categorized as strong sell, sell, reduce, hold, moderate buy, buy, or strong buy. The aggegreate price target represents the average potential upside for the consensus price target of individual holdings in the ETF.XBI Aggregate RatingModerate Buy 2.71Holdings in XBI have an aggregate rating of Moderate Buy based on 444 analyst ratings issued in the past year covering 25 companies (33.2% of the portfolio).XBI Aggregate Price Target$154.18High Prediction$154.18Average Prediction$154.18Low Prediction$154.18Holdings in XBI have an aggregate price target of $154.18 and a range of $154.18 to $154.18 covering 25 companies (33.2% of the portfolio).XBI Consensus Ratings of HoldingsStrong Buy0 Strong Buy rating(s)Buy1 Buy rating(s)Moderate Buy21 Moderate Buy rating(s)Hold3 Hold rating(s)Reduce0 Reduce rating(s)Sell0 Sell rating(s)Strong Sell0 Strong Sell rating(s) Ratings for Stocks Held by SPDR S&P Biotech ETF Strong Sell Sell Reduce Hold Moderate Buy Buy Strong Buy Ratings for the Top 25 XBI Holdings ExportWeight In ETFCompanyShare PriceMarketRank™Consensus Rating ScoreConsensus Price TargetPossible UpsideNumber of RatingsIndicator(s)ViewRatings1.76%TWSTTwist Bioscience$143.07+3.6%1.8159 of 5 stars2.50$98.45 -31.2%12Gap Up1.61%ORKAOruka Therapeutics$93.55+1.5%3.4307 of 5 stars2.82$133.00 42.2%11Trending NewsInsider Trade1.55%APGEApogee Therapeutics$135.071.5896 of 5 stars2.16$126.77 -6.1%19Positive News1.46%PRAXPraxis Precision Medicines$308.99-1.2%3.0628 of 5 stars2.95$585.95 89.6%21Positive News1.39%KYMRKymera Therapeutics$116.33+2.8%1.9117 of 5 stars2.88$131.63 13.1%25Analyst Forecast1.37%NTRANatera$345.34-1.6%1.9269 of 5 stars2.83$330.83 -4.2%23Positive News1.37%DNTHDianthus Therapeutics$102.49-2.2%2.281 of 5 stars2.93$129.83 26.7%151.36%HALOHalozyme Therapeutics$108.44+2.1%3.1329 of 5 stars2.62$91.20 -15.9%131.36%PTGXProtagonist Therapeutics$142.84-0.4%1.6907 of 5 stars2.89$147.13 3.0%181.33%RVMDRevolution Medicines$195.92-4.4%3.2609 of 5 stars2.95$226.17 15.4%21Insider Trade1.32%MRNAModerna$145.62+1.3%2.097 of 5 stars2.08$76.72 -47.3%24Trending NewsInsider Trade1.31%INSMInsmed$122.58+2.2%3.2132 of 5 stars3.00$204.91 67.2%25Analyst Forecast1.30%CGONCG Oncology$74.12+2.2%2.8755 of 5 stars2.73$87.78 18.4%11Positive News1.29%RYTMRhythm Pharmaceuticals$98.01+1.3%2.7547 of 5 stars2.75$140.67 43.5%20Positive NewsAnalyst ForecastInsider Trade1.29%SYRESpyre Therapeutics$91.17+0.2%2.592 of 5 stars2.87$109.69 20.3%15Positive News1.28%REGNRegeneron Pharmaceuticals$774.61+0.1%3.8427 of 5 stars2.58$802.18 3.6%241.27%ERASErasca$15.36-5.5%2.094 of 5 stars2.64$22.09 43.8%111.25%TVTXTravere Therapeutics$63.48+1.6%1.7437 of 5 stars2.75$68.00 7.1%12Positive News1.23%PCVXVaxcyte$58.77-0.7%2.0334 of 5 stars2.57$98.00 66.8%71.22%ROIVRoivant Sciences$39.57+0.2%1.7436 of 5 stars2.85$41.42 4.7%13Analyst Forecast1.20%RLAYRelay Therapeutics$18.84-0.7%2.3165 of 5 stars2.93$25.92 37.6%141.18%AMGNAmgen$376.35+0.2%3.5819 of 5 stars2.33$381.68 1.4%301.16%BMRNBioMarin Pharmaceutical$64.73+0.4%4.5955 of 5 stars2.70$89.17 37.8%23Analyst Forecast1.15%ARWRArrowhead Pharmaceuticals$65.79-6.9%2.801 of 5 stars2.64$99.15 50.7%14Trending NewsHigh Trading Volume1.15%BBIOBridgeBio Pharma$68.30-0.1%3.7477 of 5 stars2.83$102.61 50.2%23Options VolumeHigh Trading Volume This page (NYSEARCA:XBI) was last updated on 9/17/2026 by MarketBeat.com Staff. 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