SPDR S&P Biotech ETF Rating $150.90 -5.29 (-3.39%) Closing price 10/6/2026 04:10 PM EasternExtended Trading$150.28 -0.62 (-0.41%) As of 06:37 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Ratings Stock AnalysisChartDividendHoldingsNews and TrendsOwnershipRatingsShort Interest SPDR S&P Biotech ETF Aggregate Rating and Price Target (2026)How MarketBeat Aggregates ETF Rating and Price TargetMarketBeat calculates the aggregate rating and price target for an ETF by considering the weight of each stock in its portfolio. These ratings and price targets are based on the most recent ratings given by Wall Street analysts over the past year. The aggregate rating reviews the ETF's overall performance and is categorized as strong sell, sell, reduce, hold, moderate buy, buy, or strong buy. The aggegreate price target represents the average potential upside for the consensus price target of individual holdings in the ETF.XBI Aggregate RatingModerate Buy 2.65Holdings in XBI have an aggregate rating of Moderate Buy based on 475 analyst ratings issued in the past year covering 25 companies (38.3% of the portfolio).XBI Aggregate Price Target$150.90High Prediction$150.90Average Prediction$150.90Low Prediction$150.90Holdings in XBI have an aggregate price target of $150.90 and a range of $150.90 to $150.90 covering 25 companies (38.3% of the portfolio).XBI Consensus Ratings of HoldingsStrong Buy0 Strong Buy rating(s)Buy1 Buy rating(s)Moderate Buy19 Moderate Buy rating(s)Hold5 Hold rating(s)Reduce0 Reduce rating(s)Sell0 Sell rating(s)Strong Sell0 Strong Sell rating(s) Ratings for Stocks Held by SPDR S&P Biotech ETF Strong Sell Sell Reduce Hold Moderate Buy Buy Strong Buy Ratings for the Top 25 XBI Holdings ExportWeight In ETFCompanyShare PriceConsensus RatingConsensus Price TargetPossible UpsideNumber of RatingsMarketRank™Indicator(s)ViewRatings2.37%TWSTTwist Bioscience$166.97-18.6%Moderate Buy$115.27 -31.0%121.3629 of 5 starsTrending NewsInsider TradeGap UpHigh Trading Volume2.17%MRNAModerna$187.46-7.8%Hold$77.83 -58.5%251.9426 of 5 starsTrending News1.87%NTRANatera$400.65-5.9%Moderate Buy$347.02 -13.4%232.2271 of 5 starsTrending NewsAnalyst ForecastInsider Trade1.56%IOVAIovance Biotherapeutics$12.96-8.4%Moderate Buy$12.40 -4.3%121.8617 of 5 stars1.55%SYRESpyre Therapeutics$80.11-13.6%Moderate Buy$109.71 37.0%162.5647 of 5 starsTrending NewsHigh Trading Volume1.54%UTHRUnited Therapeutics$541.62+1.0%Moderate Buy$621.00 14.7%143.9227 of 5 starsInsider Trade1.54%ABBVAbbVie$266.65+0.3%Moderate Buy$273.82 2.7%304.1345 of 5 starsTrending NewsAnalyst Forecast1.54%BIIBBiogen$222.89-0.3%Moderate Buy$230.14 3.3%323.4526 of 5 starsTrending News1.53%CRSPCRISPR Therapeutics$54.00-5.8%Moderate Buy$67.94 25.8%183.0076 of 5 stars1.49%AMGNAmgen$402.60-0.1%Hold$385.25 -4.3%303.4369 of 5 starsAnalyst Forecast1.48%GRALGRAIL$137.28-10.9%Hold$102.70 -25.2%121.0519 of 5 starsGap Up1.46%HALOHalozyme Therapeutics$109.72+1.3%Moderate Buy$91.20 -16.9%123.037 of 5 stars1.46%EXELExelixis$58.33-0.9%Hold$50.29 -13.8%202.9337 of 5 stars1.45%RVMDRevolution Medicines$199.87-3.8%Moderate Buy$234.33 17.2%243.4849 of 5 stars1.44%GILDGilead Sciences$144.23-0.3%Moderate Buy$158.78 10.1%294.2412 of 5 starsAnalyst Revision1.44%PCVXVaxcyte$66.70-9.6%Moderate Buy$108.60 62.8%83.1615 of 5 starsTrending NewsAnalyst ForecastOptions VolumeHigh Trading Volume1.43%TGTXTG Therapeutics$52.19-3.2%Hold$63.00 20.7%93.8776 of 5 stars1.40%PTGXProtagonist Therapeutics$138.69-1.4%Moderate Buy$147.13 6.1%181.8006 of 5 stars1.40%VRTXVertex Pharmaceuticals$502.31-0.2%Moderate Buy$575.13 14.5%233.9707 of 5 stars1.40%KRYSKrystal Biotech$326.81-2.4%Buy$377.20 15.4%144.4614 of 5 starsPositive News1.37%PTCTPTC Therapeutics$63.70+0.1%Moderate Buy$99.08 55.5%153.6334 of 5 stars1.37%ALKSAlkermes$41.65-2.6%Moderate Buy$54.47 30.8%193.2617 of 5 stars1.35%NBIXNeurocrine Biosciences$145.51+0.9%Moderate Buy$202.05 38.9%244.6919 of 5 starsAnalyst Forecast1.34%ORKAOruka Therapeutics$80.18-5.0%Moderate Buy$128.91 60.8%112.9592 of 5 stars1.31%INCYIncyte$112.73-1.2%Moderate Buy$127.45 13.1%253.8964 of 5 starsAnalyst Forecast This page (NYSEARCA:XBI) was last updated on 10/7/2026 by MarketBeat.com Staff. 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