SPDR S&P Biotech ETF (XBI) Holdings List

$155.38 +3.79 (+2.50%)

As of 06/26/2026 04:10 PM Eastern

What stocks does XBI hold?

The SPDR S&P Biotech ETF (XBI) top stock holdings include TG Therapeutics, Travere Therapeutics, and Twist Bioscience. The top 25 XBI holdings ordered by weight make up 35.63% of the total fund. XBI is an equity fund in the sector category that invests in publicly traded companies, focused on health care strategies within the North America region. This page includes a complete XBI stock holdings list ranked by weight, along with a full breakdown of sector, geographic, industry, and currency exposure.

Top 25 XBI Holdings

Rank	Company	Current Price	Weight	Shares Held
1	TGTX TG Therapeutics	$55.83 +4.1%	2.03%	3,400,160
2	TVTX Travere Therapeutics	$58.85 -0.3%	2.03%	3,223,164
3	TWST Twist Bioscience	$99.84 +3.3%	1.96%	2,035,388
4	ALKS Alkermes	$55.08 +4.3%	1.77%	3,434,430
5	RVMD Revolution Medicines	$182.08 +2.2%	1.75%	957,730
6	ARWR Arrowhead Pharmaceuticals	$78.89 -0.5%	1.54%	1,641,689
7	KRYS Krystal Biotech	$372.25 +3.4%	1.48%	374,066
8	EXEL Exelixis	$54.77 +2.9%	1.39%	2,284,559
9	BEAM Beam Therapeutics	$34.81 +2.6%	1.38%	3,657,408
10	NUVL Nuvalent	$123.52 0.0%	1.36%	953,354
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11	CYTK Cytokinetics	$82.17 +1.7%	1.36%	1,499,091
12	NBIX Neurocrine Biosciences	$168.52 +2.6%	1.36%	736,290
13	PTCT PTC Therapeutics	$84.43 -0.1%	1.32%	1,452,465
14	VCYT Veracyte	$60.49 +3.3%	1.31%	2,203,821
15	APGE Apogee Therapeutics	$132.55 -0.1%	1.31%	1,277,267
16	MDGL Madrigal Pharmaceuticals	$512.65 -0.2%	1.28%	221,055
17	PTGX Protagonist Therapeutics	$121.88 -0.6%	1.28%	988,693
18	NTRA Natera	$261.91 +0.4%	1.27%	485,138
19	MIRM Mirum Pharmaceuticals	$123.59 +5.4%	1.23%	1,039,625
20	MRNA Moderna	$67.27 +12.6%	1.22%	1,704,425
21	SYRE Spyre Therapeutics	$87.89 -0.9%	1.22%	1,203,797
22	KYMR Kymera Therapeutics	$108.12 -7.2%	1.22%	1,170,133
23	SRRK Scholar Rock	$54.76 +1.8%	1.20%	2,209,091
24	RYTM Rhythm Pharmaceuticals	$109.84 +1.5%	1.18%	1,059,673
25	ARQT Arcutis Biotherapeutics	$27.00 +1.2%	1.18%	3,870,761

XBI Geographic Exposure

XBI's largest geographic exposure is United States at 93.3%, followed by Ireland at 1.3%.

United States
93.3%
Ireland
1.3%
Bermuda
1.2%
Netherlands
1.1%
Switzerland
1.1%
Virgin Islands, British
0.6%
Canada
0.2%

XBI Currency Exposure

XBI is exclusively exposed to USD.

USD
100.0%

XBI Sector Exposure

XBI's largest sector exposure is Health Care at 98.0%, followed by Consumer Discretionary at 0.2%.

Health Care
98.0%
Consumer Discretionary
0.2%
Energy
0.2%

XBI Industry Exposure

XBI's largest industry exposure is Biotechnology at 93.8%, followed by Health Care Equipment & Supplies at 1.9%.

Biotechnology
93.8%
Health Care Equipment & Supplies
1.9%
Diversified Consumer Services
1.3%
Health Care Providers & Services
1.2%
Renewable Energy
0.2%

XBI Sub-Industry Exposure

XBI's largest sub-industry exposure is Biotechnology at 92.8%, followed by Life Sciences Tools & Services at 1.5%.

Biotechnology
92.8%
Life Sciences Tools & Services
1.5%
Health Care Services
1.2%
Pharmaceuticals
1.0%
Health Care Equipment
0.3%
Renewable Energy Equipment
0.2%
Health Care Supplies
0.1%

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This page (NYSEARCA:XBI) was last updated on 6/27/2026 by MarketBeat.com Staff.

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SPDR S&P Biotech ETF (XBI) Holdings List