SPDR S&P Biotech ETF (XBI) Holdings List

$130.80 -4.05 (-3.00%)

As of 02:41 PM Eastern

What stocks does XBI hold?

The SPDR S&P Biotech ETF (XBI) top stock holdings include Apellis Pharmaceuticals, Revolution Medicines, and Travere Therapeutics. The top 25 XBI holdings ordered by weight make up 32.66% of the total fund. XBI is an equity fund in the sector category that invests in publicly traded companies, focused on health care strategies within the North America region. This page includes a complete XBI stock holdings list ranked by weight, along with a full breakdown of sector, geographic, industry, and currency exposure.

Top 25 XBI Holdings

Rank	Company	Current Price	Weight	Shares Held
1	APLS Apellis Pharmaceuticals	$41.03	1.87%	3,778,549
2	RVMD Revolution Medicines	$142.34 -4.8%	1.65%	948,345
3	TVTX Travere Therapeutics	$42.87 -2.8%	1.62%	3,191,708
4	ARWR Arrowhead Pharmaceuticals	$76.81 -3.6%	1.44%	1,625,538
5	TWST Twist Bioscience	$48.79 -7.9%	1.42%	2,015,363
6	SMMT Summit Therapeutics	$16.94 -6.6%	1.40%	5,424,733
7	ALKS Alkermes	$37.83 -1.4%	1.38%	3,401,009
8	TGTX TG Therapeutics	$39.94 -2.1%	1.37%	3,367,048
9	MDGL Madrigal Pharmaceuticals	$529.53 -1.9%	1.36%	218,830
10	BEAM Beam Therapeutics	$27.78 -5.9%	1.32%	3,621,468
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11	APGE Apogee Therapeutics	$81.01 -3.5%	1.26%	1,264,718
12	SRRK Scholar Rock	$49.47 -3.5%	1.23%	2,187,361
13	PRAX Praxis Precision Medicines	$337.17 -2.4%	1.22%	318,014
14	EXEL Exelixis	$50.07 -2.0%	1.21%	2,262,253
15	MIRM Mirum Pharmaceuticals	$105.76 -5.1%	1.21%	1,029,446
16	UTHR United Therapeutics	$566.98 -1.5%	1.19%	173,369
17	NTRA Natera	$188.73 -4.2%	1.19%	480,406
18	CELC Celcuity	$134.35 -0.3%	1.19%	815,946
19	CRSP CRISPR Therapeutics	$48.42 -4.0%	1.19%	1,891,634
20	KRYS Krystal Biotech	$308.64 -2.4%	1.17%	370,357
21	PTGX Protagonist Therapeutics	$102.89 -2.5%	1.17%	979,024
22	NBIX Neurocrine Biosciences	$158.18 -0.5%	1.16%	729,133
23	INCY Incyte	$95.16 -2.5%	1.15%	997,827
24	CGON CG Oncology	$67.75 -2.6%	1.15%	1,423,574
25	CYTK Cytokinetics	$75.81 -3.6%	1.14%	1,484,440

XBI Geographic Exposure

XBI's largest geographic exposure is United States at 93.6%, followed by Ireland at 1.7%.

United States
93.6%
Ireland
1.7%
Switzerland
1.2%
Bermuda
1.1%
Netherlands
0.6%
Virgin Islands, British
0.4%
Canada
0.1%

XBI Currency Exposure

XBI is exclusively exposed to USD.

USD
100.0%

XBI Sector Exposure

XBI's largest sector exposure is Health Care at 97.2%, followed by Consumer Discretionary at 2.0%.

Health Care
97.2%
Consumer Discretionary
2.0%
Energy
0.2%

XBI Industry Exposure

XBI's largest industry exposure is Biotechnology at 92.8%, followed by Health Care Equipment & Supplies at 2.0%.

Biotechnology
92.8%
Health Care Equipment & Supplies
2.0%
Distributors
1.8%
Diversified Consumer Services
1.3%
Health Care Providers & Services
1.1%
Renewable Energy
0.2%

XBI Sub-Industry Exposure

XBI's largest sub-industry exposure is Biotechnology at 94.0%, followed by Life Sciences Tools & Services at 1.5%.

Biotechnology
94.0%
Life Sciences Tools & Services
1.5%
Health Care Services
1.1%
Pharmaceuticals
0.8%
Health Care Equipment
0.4%
Renewable Energy Equipment
0.2%
Health Care Supplies
0.1%

XBI Coupon Exposure

XBI's largest coupon exposure is 2-4 at 0.1%.

2-4
0.1%

XBI Maturity Exposure

XBI's largest maturity exposure is 3-5 at 0.1%.

3-5
0.1%

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This page (NYSEARCA:XBI) was last updated on 5/15/2026 by MarketBeat.com Staff.

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SPDR S&P Biotech ETF (XBI) Holdings List