SPDR S&P Biotech ETF (XBI) Holdings List

$128.67 -4.75 (-3.56%)

As of 06/5/2026 04:10 PM Eastern

What stocks does XBI hold?

The SPDR S&P Biotech ETF (XBI) top stock holdings include Revolution Medicines, Travere Therapeutics, and TG Therapeutics. The top 25 XBI holdings ordered by weight make up 34.22% of the total fund. XBI is an equity fund in the sector category that invests in publicly traded companies, focused on health care strategies within the North America region. This page includes a complete XBI stock holdings list ranked by weight, along with a full breakdown of sector, geographic, industry, and currency exposure.

Top 25 XBI Holdings

Rank	Company	Current Price	Weight	Shares Held
1	RVMD Revolution Medicines	$149.23 -4.1%	1.78%	981,670
2	TVTX Travere Therapeutics	$45.81 -0.8%	1.75%	3,304,362
3	TGTX TG Therapeutics	$40.16 -1.0%	1.62%	3,485,679
4	ALKS Alkermes	$42.80 -1.3%	1.55%	3,520,987
5	TWST Twist Bioscience	$69.22 -6.4%	1.51%	2,086,682
6	ARWR Arrowhead Pharmaceuticals	$73.09 -2.8%	1.51%	1,682,875
7	NBIX Neurocrine Biosciences	$163.88 -2.1%	1.41%	754,748
8	CYTK Cytokinetics	$71.48 -1.1%	1.41%	1,536,699
9	EXEL Exelixis	$52.70 +0.4%	1.40%	2,342,030
10	MDGL Madrigal Pharmaceuticals	$486.98 -1.2%	1.40%	226,597
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11	CELC Celcuity	$88.28 -4.5%	1.39%	844,619
12	KRYS Krystal Biotech	$301.00 -2.2%	1.37%	383,472
13	PRAX Praxis Precision Medicines	$254.00 -4.1%	1.35%	329,332
14	SRRK Scholar Rock	$44.30 -2.3%	1.30%	2,264,539
15	BEAM Beam Therapeutics	$29.40 -10.5%	1.28%	3,749,419
16	APGE Apogee Therapeutics	$86.92 -4.4%	1.27%	1,309,295
17	MIRM Mirum Pharmaceuticals	$93.48 +1.1%	1.25%	1,065,641
18	PTCT PTC Therapeutics	$70.97 +0.5%	1.22%	1,489,005
19	UTHR United Therapeutics	$549.87 +0.4%	1.22%	179,550
20	VCYT Veracyte	$48.73 -2.4%	1.21%	2,259,425
21	IMVT Immunovant	$31.11 -4.8%	1.21%	2,962,118
22	NTRA Natera	$215.31 -3.1%	1.21%	497,324
23	PTGX Protagonist Therapeutics	$97.38 -5.3%	1.20%	1,013,595
24	HALO Halozyme Therapeutics	$71.53 -0.1%	1.20%	1,470,953
25	INCY Incyte	$102.38 +1.1%	1.20%	1,033,134

XBI Geographic Exposure

XBI's largest geographic exposure is United States at 93.2%, followed by Ireland at 1.9%.

United States
93.2%
Ireland
1.9%
Switzerland
1.3%
Bermuda
1.2%
Netherlands
0.6%
Virgin Islands, British
0.6%
Canada
0.1%

XBI Currency Exposure

XBI is exclusively exposed to USD.

USD
100.0%

XBI Sector Exposure

XBI's largest sector exposure is Health Care at 98.9%, followed by Consumer Discretionary at 0.2%.

Health Care
98.9%
Consumer Discretionary
0.2%
Energy
0.1%

XBI Industry Exposure

XBI's largest industry exposure is Biotechnology at 94.1%, followed by Health Care Equipment & Supplies at 2.6%.

Biotechnology
94.1%
Health Care Equipment & Supplies
2.6%
Health Care Providers & Services
1.3%
Diversified Consumer Services
1.1%
Renewable Energy
0.1%

XBI Sub-Industry Exposure

XBI's largest sub-industry exposure is Biotechnology at 93.1%, followed by Life Sciences Tools & Services at 2.0%.

Biotechnology
93.1%
Life Sciences Tools & Services
2.0%
Health Care Services
1.3%
Pharmaceuticals
0.8%
Health Care Equipment
0.5%
Renewable Energy Equipment
0.1%
Health Care Supplies
0.1%

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This page (NYSEARCA:XBI) was last updated on 6/7/2026 by MarketBeat.com Staff.

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SPDR S&P Biotech ETF (XBI) Holdings List