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Vertex Pharmaceuticals (VRTX) Stock Forecast & Price Target

Vertex Pharmaceuticals logo
$447.97 +10.75 (+2.46%)
Closing price 04:00 PM Eastern
Extended Trading
$447.50 -0.47 (-0.10%)
As of 04:17 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Vertex Pharmaceuticals - Analysts' Recommendations and Stock Price Forecast (2026)

Consensus Rating

Sell
0
Hold
3
Buy
22

Based on 25 Wall Street analysts who have issued ratings for Vertex Pharmaceuticals in the last 12 months, the stock has a consensus rating of "Moderate Buy." Out of the 25 analysts, 3 have given a hold rating, and 22 have given a buy rating for VRTX.

Consensus Price Target

$555.91
24.10% Upside
According to the 25 analysts' twelve-month price targets for Vertex Pharmaceuticals, the average price target is $555.91. The highest price target for VRTX is $641.00, while the lowest price target for VRTX is $436.00. The average price target represents a forecasted upside of 24.10% from the current price of $447.97.
MarketBeat calculates consensus analyst ratings for stocks using the most recent rating from each Wall Street analyst that has rated a stock within the last twelve months. Each analyst's rating is normalized to a standardized rating score of 1 (sell), 2 (hold), 3 (buy) or 4 (strong buy). Analyst consensus ratings scores are calculated using the mean average of the number of normalized sell, hold, buy and strong buy ratings from Wall Street analysts. Each stock's consensus analyst rating is derived from its calculated consensus ratings score (0 to .5 = Strong Sell, .5 to 1 = Sell, 1 to 1.5 = Reduce, 1.5 to 2.5 = Hold, 2.5 to 3.0 = Moderate Buy, 3.0 to 3.5 = Buy, >3.5 = Strong Buy). MarketBeat's consensus price targets are a mean average of the most recent available price targets set by each analyst that has set a price target for the stock in the last twelve months. MarketBeat's consensus ratings and consensus price targets may differ from those calculated by other firms due to differences in methodology and available data.
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VRTX Analyst Ratings Over Time

TypeCurrent Forecast
5/28/25 to 5/28/26
1 Month Ago
4/28/25 to 4/28/26
3 Months Ago
2/27/25 to 2/27/26
1 Year Ago
5/28/24 to 5/28/25
Strong Buy
0 Strong Buy rating(s)
1 Strong Buy rating(s)
0 Strong Buy rating(s)
1 Strong Buy rating(s)
Buy
22 Buy rating(s)
22 Buy rating(s)
22 Buy rating(s)
15 Buy rating(s)
Hold
3 Hold rating(s)
6 Hold rating(s)
5 Hold rating(s)
13 Hold rating(s)
Sell
0 Sell rating(s)
0 Sell rating(s)
0 Sell rating(s)
0 Sell rating(s)
Consensus Price Target$555.91$555.00$542.00$515.04
Forecasted Upside24.10% Upside29.03% Upside9.09% Upside15.71% Upside
Consensus RatingModerate BuyModerate BuyModerate BuyModerate Buy

VRTX Analyst Recommendations By Month

The chart below shows how a company's ratings by analysts have changed over time. Each bar represents the previous year of ratings for that month. Within each bar, the sell ratings are shown in red, the hold ratings are shown in yellow, the buy ratings are shown in green, and the strong buy ratings are shown in dark green.
Skip Chart & View Analyst Rating History

VRTX Price Targets by Month

The chart below shows how a company's share price and consensus price target have changed over time. The dark blue line represents the company's actual price. The lighter blue line represents the stock's consensus price target. The even lighter blue range in the background of the two lines represents the low price target and the high price target for each stock.
Skip Chart and View Analyst Price Target HistorySkip Chart & View Price History Table

Vertex Pharmaceuticals Stock vs. The Competition

TypeVertex PharmaceuticalsMedical CompaniesBroader Market
Consensus Rating Score
2.88
2.30
2.52
Consensus RatingModerate BuyHoldModerate Buy
Predicted Upside27.15% Upside1,703.48% Upside14.88% Upside
News Sentiment Rating
Positive News

See Recent VRTX News
Neutral News
Positive News
DateBrokerageAnalystActionRatingPrice TargetReport Date
Upside/Downside
Details
5/27/2026
Truist Financial Corporation logo
Truist Financial
3 of 5 stars
 Initiated CoverageBuy$542.00+23.08%
5/18/2026 UpgradeHold (C+)Buy (B-)
5/6/2026
Barclays PLC logo
Barclays
3 of 5 stars
Eliana Merle
Not Rated
Boost TargetOverweight$607.00 ➝ $615.00+44.92%
5/5/2026Boost TargetOverweight$612.00 ➝ $616.00+47.34%
5/5/2026Boost TargetOutperform$541.00 ➝ $543.00+26.32%
5/5/2026Lower TargetOutperform$577.00 ➝ $572.00+33.07%
5/5/2026Lower TargetHold$437.00 ➝ $436.00+1.43%
3/18/2026UpgradeHoldBuy$575.00+24.33%
3/10/2026Boost TargetBuy$571.00 ➝ $598.00+18.47%
3/10/2026Boost TargetBuy$575.00 ➝ $585.00+16.38%
3/10/2026Initiated CoverageBuy$580.00+25.85%
3/10/2026Boost TargetOutperform$540.00 ➝ $600.00+30.19%
3/10/2026Boost TargetBuy$591.00 ➝ $641.00+39.08%
2/13/2026Boost TargetOutperform$495.00 ➝ $558.00+12.34%
2/13/2026 Reiterated RatingOverweight$590.00+20.98%
2/13/2026Boost TargetHold$445.00 ➝ $466.00+0.21%
1/26/2026Boost TargetBuy$535.00 ➝ $545.00+15.02%
1/23/2026Boost TargetOutperform$475.00 ➝ $530.00+13.41%
1/6/2026UpgradePeer PerformOutperform$548.00+22.10%
12/29/2025Boost TargetOutperform$456.00 ➝ $525.00+13.42%
12/10/2025Boost TargetOverweight$460.00 ➝ $515.00+15.74%
10/8/2025Boost TargetOverweight$517.00 ➝ $530.00+26.34%
9/2/2025Initiated CoverageMarket Perform
8/6/2025Lower TargetBuy$558.00 ➝ $546.00+40.91%
8/5/2025Set TargetOutperform$557.00 ➝ $530.00+12.22%
5/23/2025DowngradeStrong-BuyHold
5/6/2025 Reiterated RatingBuy
5/6/2025 Reiterated RatingOutperform
5/6/2025Reiterated RatingHold
1/27/2025Lower TargetOverweight$535.00 ➝ $533.00+20.72%
7/23/2024 Boost TargetBuy$450.00 ➝ $500.00+1.60%
6/27/2024Initiated CoverageBuy$545.00+14.98%
6/17/2024 Boost TargetBuy$465.00 ➝ $550.00+15.48%

Analyst ratings data on MarketBeat is provided by Benzinga and other data providers. This page was last refreshed on Thursday at 04:19 PM ET.


Should I Buy Vertex Pharmaceuticals Stock? VRTX Pros and Cons Explained

These pros and cons were generated based on recent news and financial data from MarketBeat in order to provide readers with the fastest and most accurate insights. They were last updated on Wednesday, May 20, 2026. Please send any questions or comments about these Vertex Pharmaceuticals pros and cons to contact@marketbeat.com.

Vertex Pharmaceuticals
Bull Case

green Wall Street bull icon

Here are some ways that investors could benefit from investing in Vertex Pharmaceuticals Incorporated:

  • The company recently reported earnings per share of $4.47, exceeding analysts' expectations, which indicates strong financial performance and potential for future growth.
  • Vertex Pharmaceuticals Incorporated has a robust return on equity of 23.86%, suggesting effective management and profitability relative to shareholder equity.
  • With a net margin of 35.51%, the company demonstrates a strong ability to convert revenue into profit, which is attractive for investors seeking companies with solid financial health.
  • The current stock price is around $500, reflecting a significant market capitalization of approximately $110.80 billion, indicating strong investor confidence and market presence.
  • Analysts forecast earnings per share of approximately 16.97 for the current year, suggesting continued growth and profitability potential for investors.

Vertex Pharmaceuticals
Bear Case

red Wall Street bear icon

Investors should be bearish about investing in Vertex Pharmaceuticals Incorporated for these reasons:

  • The stock has a P/E ratio of 25.89, which may indicate that it is overvalued compared to its earnings, potentially leading to a correction in stock price.
  • Despite recent growth, the company operates in a highly competitive biotechnology sector, which could impact its market share and profitability in the future.
  • Vertex Pharmaceuticals Incorporated's beta of 0.30 suggests lower volatility compared to the market, which may limit potential high returns for investors looking for aggressive growth.
  • Institutional investors hold a significant 90.96% of the company's stock, which could lead to less liquidity and more volatility if these investors decide to sell.
  • Recent target price adjustments by analysts indicate mixed sentiments, with some lowering their expectations, which could signal potential challenges ahead for the company.

VRTX Forecast - Frequently Asked Questions

According to the research reports of 25 Wall Street equities research analysts, the average twelve-month stock price forecast for Vertex Pharmaceuticals is $555.91, with a high forecast of $641.00 and a low forecast of $436.00.

25 Wall Street research analysts have issued "buy," "hold," and "sell" ratings for Vertex Pharmaceuticals in the last twelve months. There are currently 3 hold ratings and 22 buy ratings for the stock. The consensus among Wall Street research analysts is that investors should "moderate buy" VRTX shares.

According to analysts, Vertex Pharmaceuticals's stock has a predicted upside of 24.10% based on their 12-month stock forecasts.

Over the previous 90 days, Vertex Pharmaceuticals's stock had 4 upgrades and 1 downgrade by analysts.

Analysts like Vertex Pharmaceuticals more than other "medical" companies. The consensus rating for Vertex Pharmaceuticals is Moderate Buy while the average consensus rating for "medical" companies is Hold. Learn more on how VRTX compares to other companies.


This page (NASDAQ:VRTX) was last updated on 5/28/2026 by MarketBeat.com Staff.
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