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Vertex Pharmaceuticals (VRTX) Competitors

Vertex Pharmaceuticals logo
$538.60 -4.02 (-0.74%)
Closing price 04:00 PM Eastern
Extended Trading
$542.36 +3.76 (+0.70%)
As of 05:42 PM Eastern
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VRTX vs. AMZN, AXSM, CRSP, EDIT, and GOOG

Should you buy Vertex Pharmaceuticals stock or one of its competitors? Vertex Pharmaceuticals's main competitors and comparable companies include Amazon.com (AMZN), Axsome Therapeutics (AXSM), CRISPR Therapeutics (CRSP), Editas Medicine (EDIT), and Alphabet (GOOG). Companies are selected based on similarities in market, industry, and size.

How does Vertex Pharmaceuticals compare to Amazon.com?

Amazon.com (NASDAQ:AMZN) and Vertex Pharmaceuticals (NASDAQ:VRTX) are related large-cap companies, but which is the better investment? We will compare the two companies based on the strength of their analyst recommendations, institutional ownership, earnings, dividends, media sentiment, profitability, risk and valuation.

Vertex Pharmaceuticals has a net margin of 30.70% compared to Amazon.com's net margin of 16.90%. Vertex Pharmaceuticals' return on equity of 21.98% beat Amazon.com's return on equity.

Company Net Margins Return on Equity Return on Assets
Amazon.com16.90% 15.72% 7.79%
Vertex Pharmaceuticals 30.70%21.98%15.50%

72.2% of Amazon.com shares are owned by institutional investors. Comparatively, 91.0% of Vertex Pharmaceuticals shares are owned by institutional investors. 8.9% of Amazon.com shares are owned by insiders. Comparatively, 0.2% of Vertex Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Amazon.com has a beta of 1.49, indicating that its stock price is 49% more volatile than the broader market. Comparatively, Vertex Pharmaceuticals has a beta of 0.28, indicating that its stock price is 72% less volatile than the broader market.

Amazon.com has higher revenue and earnings than Vertex Pharmaceuticals. Amazon.com is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amazon.com$716.92B4.03$77.67B$12.3721.62
Vertex Pharmaceuticals$12.00B11.46$3.95B$15.5434.92

In the previous week, Amazon.com had 259 more articles in the media than Vertex Pharmaceuticals. MarketBeat recorded 275 mentions for Amazon.com and 16 mentions for Vertex Pharmaceuticals. Amazon.com's average media sentiment score of 0.95 beat Vertex Pharmaceuticals' score of 0.83 indicating that Amazon.com is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amazon.com
177 Very Positive mention(s)
56 Positive mention(s)
25 Neutral mention(s)
12 Negative mention(s)
4 Very Negative mention(s)
Positive
Vertex Pharmaceuticals
8 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive

Amazon.com currently has a consensus price target of $321.74, indicating a potential upside of 20.30%. Vertex Pharmaceuticals has a consensus price target of $596.44, indicating a potential upside of 9.92%. Given Amazon.com's stronger consensus rating and higher probable upside, analysts plainly believe Amazon.com is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amazon.com
0 Sell rating(s)
3 Hold rating(s)
55 Buy rating(s)
2 Strong Buy rating(s)
2.98
Vertex Pharmaceuticals
0 Sell rating(s)
2 Hold rating(s)
25 Buy rating(s)
1 Strong Buy rating(s)
2.96

Summary

Amazon.com beats Vertex Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

How does Vertex Pharmaceuticals compare to Axsome Therapeutics?

Vertex Pharmaceuticals (NASDAQ:VRTX) and Axsome Therapeutics (NASDAQ:AXSM) are both healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their profitability, risk, analyst recommendations, dividends, media sentiment, earnings, institutional ownership and valuation.

Vertex Pharmaceuticals presently has a consensus price target of $596.44, indicating a potential upside of 9.92%. Axsome Therapeutics has a consensus price target of $267.58, indicating a potential upside of 85.34%. Given Axsome Therapeutics' higher possible upside, analysts clearly believe Axsome Therapeutics is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vertex Pharmaceuticals
0 Sell rating(s)
2 Hold rating(s)
25 Buy rating(s)
1 Strong Buy rating(s)
2.96
Axsome Therapeutics
1 Sell rating(s)
2 Hold rating(s)
17 Buy rating(s)
1 Strong Buy rating(s)
2.86

Vertex Pharmaceuticals has a beta of 0.28, suggesting that its share price is 72% less volatile than the broader market. Comparatively, Axsome Therapeutics has a beta of 0.86, suggesting that its share price is 14% less volatile than the broader market.

Vertex Pharmaceuticals has a net margin of 30.70% compared to Axsome Therapeutics' net margin of -18.18%. Vertex Pharmaceuticals' return on equity of 21.98% beat Axsome Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Vertex Pharmaceuticals30.70% 21.98% 15.50%
Axsome Therapeutics -18.18%-198.73%-22.03%

In the previous week, Axsome Therapeutics had 2 more articles in the media than Vertex Pharmaceuticals. MarketBeat recorded 18 mentions for Axsome Therapeutics and 16 mentions for Vertex Pharmaceuticals. Vertex Pharmaceuticals' average media sentiment score of 0.83 beat Axsome Therapeutics' score of 0.23 indicating that Vertex Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vertex Pharmaceuticals
8 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive
Axsome Therapeutics
4 Very Positive mention(s)
3 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

Vertex Pharmaceuticals has higher revenue and earnings than Axsome Therapeutics. Axsome Therapeutics is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Vertex Pharmaceuticals$12.00B11.46$3.95B$15.5434.92
Axsome Therapeutics$638.50M11.89-$183.17M-$3.06N/A

91.0% of Vertex Pharmaceuticals shares are owned by institutional investors. Comparatively, 81.5% of Axsome Therapeutics shares are owned by institutional investors. 0.2% of Vertex Pharmaceuticals shares are owned by company insiders. Comparatively, 20.6% of Axsome Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Summary

Vertex Pharmaceuticals beats Axsome Therapeutics on 10 of the 15 factors compared between the two stocks.

How does Vertex Pharmaceuticals compare to CRISPR Therapeutics?

CRISPR Therapeutics (NASDAQ:CRSP) and Vertex Pharmaceuticals (NASDAQ:VRTX) are both healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their risk, institutional ownership, media sentiment, dividends, valuation, earnings, profitability and analyst recommendations.

Vertex Pharmaceuticals has a net margin of 30.70% compared to CRISPR Therapeutics' net margin of -1,812.07%. Vertex Pharmaceuticals' return on equity of 21.98% beat CRISPR Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
CRISPR Therapeutics-1,812.07% -25.59% -17.89%
Vertex Pharmaceuticals 30.70%21.98%15.50%

In the previous week, CRISPR Therapeutics had 10 more articles in the media than Vertex Pharmaceuticals. MarketBeat recorded 26 mentions for CRISPR Therapeutics and 16 mentions for Vertex Pharmaceuticals. Vertex Pharmaceuticals' average media sentiment score of 0.83 beat CRISPR Therapeutics' score of 0.47 indicating that Vertex Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
CRISPR Therapeutics
3 Very Positive mention(s)
4 Positive mention(s)
14 Neutral mention(s)
2 Negative mention(s)
2 Very Negative mention(s)
Neutral
Vertex Pharmaceuticals
8 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive

CRISPR Therapeutics currently has a consensus target price of $72.93, suggesting a potential upside of 71.11%. Vertex Pharmaceuticals has a consensus target price of $596.44, suggesting a potential upside of 9.92%. Given CRISPR Therapeutics' higher probable upside, equities analysts plainly believe CRISPR Therapeutics is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
CRISPR Therapeutics
1 Sell rating(s)
6 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
2.65
Vertex Pharmaceuticals
0 Sell rating(s)
2 Hold rating(s)
25 Buy rating(s)
1 Strong Buy rating(s)
2.96

CRISPR Therapeutics has a beta of 1.92, suggesting that its share price is 92% more volatile than the broader market. Comparatively, Vertex Pharmaceuticals has a beta of 0.28, suggesting that its share price is 72% less volatile than the broader market.

Vertex Pharmaceuticals has higher revenue and earnings than CRISPR Therapeutics. CRISPR Therapeutics is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
CRISPR Therapeutics$3.51M1,177.82-$581.60M-$4.74N/A
Vertex Pharmaceuticals$12.00B11.46$3.95B$15.5434.92

69.2% of CRISPR Therapeutics shares are held by institutional investors. Comparatively, 91.0% of Vertex Pharmaceuticals shares are held by institutional investors. 5.2% of CRISPR Therapeutics shares are held by insiders. Comparatively, 0.2% of Vertex Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Summary

Vertex Pharmaceuticals beats CRISPR Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Vertex Pharmaceuticals compare to Editas Medicine?

Vertex Pharmaceuticals (NASDAQ:VRTX) and Editas Medicine (NASDAQ:EDIT) are both healthcare companies, but which is the better business? We will compare the two companies based on the strength of their valuation, dividends, profitability, institutional ownership, risk, analyst recommendations, earnings and media sentiment.

Vertex Pharmaceuticals presently has a consensus target price of $596.44, suggesting a potential upside of 9.92%. Editas Medicine has a consensus target price of $5.83, suggesting a potential upside of 172.59%. Given Editas Medicine's higher possible upside, analysts clearly believe Editas Medicine is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vertex Pharmaceuticals
0 Sell rating(s)
2 Hold rating(s)
25 Buy rating(s)
1 Strong Buy rating(s)
2.96
Editas Medicine
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.71

91.0% of Vertex Pharmaceuticals shares are owned by institutional investors. Comparatively, 71.9% of Editas Medicine shares are owned by institutional investors. 0.2% of Vertex Pharmaceuticals shares are owned by company insiders. Comparatively, 3.1% of Editas Medicine shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Vertex Pharmaceuticals has higher revenue and earnings than Editas Medicine. Editas Medicine is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Vertex Pharmaceuticals$12.00B11.46$3.95B$15.5434.92
Editas Medicine$40.52M8.15-$160.06M-$0.62N/A

Vertex Pharmaceuticals has a net margin of 30.70% compared to Editas Medicine's net margin of -144.95%. Vertex Pharmaceuticals' return on equity of 21.98% beat Editas Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Vertex Pharmaceuticals30.70% 21.98% 15.50%
Editas Medicine -144.95%-130.43%-36.45%

In the previous week, Editas Medicine had 1 more articles in the media than Vertex Pharmaceuticals. MarketBeat recorded 17 mentions for Editas Medicine and 16 mentions for Vertex Pharmaceuticals. Vertex Pharmaceuticals' average media sentiment score of 0.83 beat Editas Medicine's score of 0.15 indicating that Vertex Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vertex Pharmaceuticals
8 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive
Editas Medicine
2 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
4 Negative mention(s)
1 Very Negative mention(s)
Neutral

Vertex Pharmaceuticals has a beta of 0.28, meaning that its stock price is 72% less volatile than the broader market. Comparatively, Editas Medicine has a beta of 2.08, meaning that its stock price is 108% more volatile than the broader market.

Summary

Vertex Pharmaceuticals beats Editas Medicine on 12 of the 16 factors compared between the two stocks.

How does Vertex Pharmaceuticals compare to Alphabet?

Vertex Pharmaceuticals (NASDAQ:VRTX) and Alphabet (NASDAQ:GOOG) are related large-cap companies, but which is the better stock? We will compare the two companies based on the strength of their institutional ownership, profitability, earnings, dividends, media sentiment, valuation, risk and analyst recommendations.

91.0% of Vertex Pharmaceuticals shares are owned by institutional investors. Comparatively, 27.3% of Alphabet shares are owned by institutional investors. 0.2% of Vertex Pharmaceuticals shares are owned by company insiders. Comparatively, 13.0% of Alphabet shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Alphabet has a net margin of 50.03% compared to Vertex Pharmaceuticals' net margin of 30.70%. Alphabet's return on equity of 43.33% beat Vertex Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Vertex Pharmaceuticals30.70% 21.98% 15.50%
Alphabet 50.03%43.33%29.24%

In the previous week, Alphabet had 150 more articles in the media than Vertex Pharmaceuticals. MarketBeat recorded 166 mentions for Alphabet and 16 mentions for Vertex Pharmaceuticals. Vertex Pharmaceuticals' average media sentiment score of 0.83 beat Alphabet's score of 0.60 indicating that Vertex Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vertex Pharmaceuticals
8 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive
Alphabet
90 Very Positive mention(s)
9 Positive mention(s)
52 Neutral mention(s)
13 Negative mention(s)
1 Very Negative mention(s)
Positive

Vertex Pharmaceuticals has a beta of 0.28, suggesting that its stock price is 72% less volatile than the broader market. Comparatively, Alphabet has a beta of 1.21, suggesting that its stock price is 21% more volatile than the broader market.

Vertex Pharmaceuticals presently has a consensus target price of $596.44, indicating a potential upside of 9.92%. Alphabet has a consensus target price of $413.38, indicating a potential upside of 39.96%. Given Alphabet's stronger consensus rating and higher possible upside, analysts plainly believe Alphabet is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vertex Pharmaceuticals
0 Sell rating(s)
2 Hold rating(s)
25 Buy rating(s)
1 Strong Buy rating(s)
2.96
Alphabet
1 Sell rating(s)
5 Hold rating(s)
35 Buy rating(s)
6 Strong Buy rating(s)
2.98

Alphabet has higher revenue and earnings than Vertex Pharmaceuticals. Alphabet is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Vertex Pharmaceuticals$12.00B11.46$3.95B$15.5434.92
Alphabet$402.84B9.01$132.17B$19.1615.41

Summary

Alphabet beats Vertex Pharmaceuticals on 13 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding VRTX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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VRTX vs. The Competition

MetricVertex PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$136.56B$4.10B$7.87B$12.09B
Dividend YieldN/A3.62%2.46%4.50%
P/E Ratio34.6624.5634.6130.52
Price / Sales11.3816.888.895.88
Price / Cash31.1226.8922.2322.80
Price / Book6.534.144.403.79
Net Income$3.95B-$22.78M$3.51B$390.55M
7 Day Performance-1.55%-2.71%-1.49%-0.29%
1 Month Performance11.00%-5.71%-3.90%-6.63%
1 Year Performance23.95%-0.30%0.94%-5.76%

Vertex Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
VRTX
Vertex Pharmaceuticals
3.1352 of 5 stars
$538.60
-0.7%
$596.44
+10.7%
+25.0%$136.56B$12.00B34.666,400
AMZN
Amazon.com
4.8025 of 5 stars
$266.93
+2.9%
$321.74
+20.5%
+9.5%$2.89T$797.46B21.581,576,000
AXSM
Axsome Therapeutics
3.5804 of 5 stars
$133.96
+1.2%
$267.58
+99.7%
+2.5%$7.05B$638.50MN/A925
CRSP
CRISPR Therapeutics
2.9499 of 5 stars
$50.04
-0.1%
$69.69
+39.3%
-18.3%$4.85B$3.51MN/A393
EDIT
Editas Medicine
2.3198 of 5 stars
$2.75
+7.0%
$5.83
+112.1%
-20.7%$422.35M$40.52MN/A87

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This page (NASDAQ:VRTX) was last updated on 11/13/2026 by MarketBeat.com Staff.
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