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Vertex Pharmaceuticals (VRTX) Competitors

Vertex Pharmaceuticals logo
$526.73 -0.94 (-0.18%)
Closing price 04:00 PM Eastern
Extended Trading
$522.69 -4.04 (-0.77%)
As of 05:38 PM Eastern
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VRTX vs. AMZN, AXSM, CRSP, EDIT, and GOOG

Should you buy Vertex Pharmaceuticals stock or one of its competitors? Vertex Pharmaceuticals's main competitors and comparable companies include Amazon.com (AMZN), Axsome Therapeutics (AXSM), CRISPR Therapeutics (CRSP), Editas Medicine (EDIT), and Alphabet (GOOG). Companies are selected based on similarities in market, industry, and size.

How does Vertex Pharmaceuticals compare to Amazon.com?

Vertex Pharmaceuticals (NASDAQ:VRTX) and Amazon.com (NASDAQ:AMZN) are related large-cap companies, but which is the better investment? We will compare the two companies based on the strength of their institutional ownership, valuation, media sentiment, risk, analyst recommendations, earnings, dividends and profitability.

Vertex Pharmaceuticals has a net margin of 35.00% compared to Amazon.com's net margin of 17.44%. Vertex Pharmaceuticals' return on equity of 23.09% beat Amazon.com's return on equity.

Company Net Margins Return on Equity Return on Assets
Vertex Pharmaceuticals35.00% 23.09% 16.72%
Amazon.com 17.44%18.00%8.97%

In the previous week, Amazon.com had 345 more articles in the media than Vertex Pharmaceuticals. MarketBeat recorded 362 mentions for Amazon.com and 17 mentions for Vertex Pharmaceuticals. Amazon.com's average media sentiment score of 1.02 beat Vertex Pharmaceuticals' score of 0.93 indicating that Amazon.com is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vertex Pharmaceuticals
9 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Amazon.com
243 Very Positive mention(s)
46 Positive mention(s)
35 Neutral mention(s)
26 Negative mention(s)
11 Very Negative mention(s)
Positive

Vertex Pharmaceuticals presently has a consensus price target of $575.13, indicating a potential upside of 9.19%. Amazon.com has a consensus price target of $321.19, indicating a potential upside of 30.21%. Given Amazon.com's higher probable upside, analysts plainly believe Amazon.com is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vertex Pharmaceuticals
0 Sell rating(s)
2 Hold rating(s)
20 Buy rating(s)
1 Strong Buy rating(s)
2.96
Amazon.com
0 Sell rating(s)
3 Hold rating(s)
56 Buy rating(s)
0 Strong Buy rating(s)
2.95

Vertex Pharmaceuticals has a beta of 0.32, indicating that its stock price is 68% less volatile than the broader market. Comparatively, Amazon.com has a beta of 1.44, indicating that its stock price is 44% more volatile than the broader market.

91.0% of Vertex Pharmaceuticals shares are owned by institutional investors. Comparatively, 72.2% of Amazon.com shares are owned by institutional investors. 0.2% of Vertex Pharmaceuticals shares are owned by company insiders. Comparatively, 8.9% of Amazon.com shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Amazon.com has higher revenue and earnings than Vertex Pharmaceuticals. Amazon.com is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Vertex Pharmaceuticals$12.00B11.14$3.95B$17.1830.66
Amazon.com$716.92B3.71$77.67B$12.4319.84

Summary

Vertex Pharmaceuticals beats Amazon.com on 9 of the 17 factors compared between the two stocks.

How does Vertex Pharmaceuticals compare to Axsome Therapeutics?

Vertex Pharmaceuticals (NASDAQ:VRTX) and Axsome Therapeutics (NASDAQ:AXSM) are both healthcare companies, but which is the superior stock? We will contrast the two businesses based on the strength of their dividends, analyst recommendations, profitability, risk, earnings, media sentiment, valuation and institutional ownership.

Vertex Pharmaceuticals has a net margin of 35.00% compared to Axsome Therapeutics' net margin of -24.68%. Vertex Pharmaceuticals' return on equity of 23.09% beat Axsome Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Vertex Pharmaceuticals35.00% 23.09% 16.72%
Axsome Therapeutics -24.68%-265.55%-28.10%

In the previous week, Vertex Pharmaceuticals had 11 more articles in the media than Axsome Therapeutics. MarketBeat recorded 17 mentions for Vertex Pharmaceuticals and 6 mentions for Axsome Therapeutics. Vertex Pharmaceuticals' average media sentiment score of 0.93 beat Axsome Therapeutics' score of 0.61 indicating that Vertex Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vertex Pharmaceuticals
9 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Axsome Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Vertex Pharmaceuticals has higher revenue and earnings than Axsome Therapeutics. Axsome Therapeutics is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Vertex Pharmaceuticals$12.00B11.14$3.95B$17.1830.66
Axsome Therapeutics$638.50M15.27-$183.17M-$3.75N/A

Vertex Pharmaceuticals has a beta of 0.32, indicating that its share price is 68% less volatile than the broader market. Comparatively, Axsome Therapeutics has a beta of 0.71, indicating that its share price is 29% less volatile than the broader market.

91.0% of Vertex Pharmaceuticals shares are held by institutional investors. Comparatively, 81.5% of Axsome Therapeutics shares are held by institutional investors. 0.2% of Vertex Pharmaceuticals shares are held by company insiders. Comparatively, 20.6% of Axsome Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Vertex Pharmaceuticals currently has a consensus price target of $575.13, suggesting a potential upside of 9.19%. Axsome Therapeutics has a consensus price target of $271.00, suggesting a potential upside of 45.59%. Given Axsome Therapeutics' higher probable upside, analysts clearly believe Axsome Therapeutics is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vertex Pharmaceuticals
0 Sell rating(s)
2 Hold rating(s)
20 Buy rating(s)
1 Strong Buy rating(s)
2.96
Axsome Therapeutics
1 Sell rating(s)
2 Hold rating(s)
18 Buy rating(s)
1 Strong Buy rating(s)
2.86

Summary

Vertex Pharmaceuticals beats Axsome Therapeutics on 12 of the 16 factors compared between the two stocks.

How does Vertex Pharmaceuticals compare to CRISPR Therapeutics?

Vertex Pharmaceuticals (NASDAQ:VRTX) and CRISPR Therapeutics (NASDAQ:CRSP) are both healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their institutional ownership, dividends, media sentiment, risk, earnings, profitability, analyst recommendations and valuation.

91.0% of Vertex Pharmaceuticals shares are owned by institutional investors. Comparatively, 69.2% of CRISPR Therapeutics shares are owned by institutional investors. 0.2% of Vertex Pharmaceuticals shares are owned by company insiders. Comparatively, 5.2% of CRISPR Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Vertex Pharmaceuticals presently has a consensus price target of $575.13, suggesting a potential upside of 9.19%. CRISPR Therapeutics has a consensus price target of $67.94, suggesting a potential upside of 21.32%. Given CRISPR Therapeutics' higher probable upside, analysts clearly believe CRISPR Therapeutics is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vertex Pharmaceuticals
0 Sell rating(s)
2 Hold rating(s)
20 Buy rating(s)
1 Strong Buy rating(s)
2.96
CRISPR Therapeutics
1 Sell rating(s)
6 Hold rating(s)
9 Buy rating(s)
2 Strong Buy rating(s)
2.67

Vertex Pharmaceuticals has a net margin of 35.00% compared to CRISPR Therapeutics' net margin of -3,368.72%. Vertex Pharmaceuticals' return on equity of 23.09% beat CRISPR Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Vertex Pharmaceuticals35.00% 23.09% 16.72%
CRISPR Therapeutics -3,368.72%-24.39%-18.25%

Vertex Pharmaceuticals has a beta of 0.32, meaning that its share price is 68% less volatile than the broader market. Comparatively, CRISPR Therapeutics has a beta of 1.76, meaning that its share price is 76% more volatile than the broader market.

In the previous week, Vertex Pharmaceuticals and Vertex Pharmaceuticals both had 17 articles in the media. Vertex Pharmaceuticals' average media sentiment score of 0.93 beat CRISPR Therapeutics' score of 0.75 indicating that Vertex Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vertex Pharmaceuticals
9 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
CRISPR Therapeutics
6 Very Positive mention(s)
4 Positive mention(s)
4 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Vertex Pharmaceuticals has higher revenue and earnings than CRISPR Therapeutics. CRISPR Therapeutics is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Vertex Pharmaceuticals$12.00B11.14$3.95B$17.1830.66
CRISPR Therapeutics$3.51M1,542.63-$581.60M-$4.76N/A

Summary

Vertex Pharmaceuticals beats CRISPR Therapeutics on 11 of the 16 factors compared between the two stocks.

How does Vertex Pharmaceuticals compare to Editas Medicine?

Vertex Pharmaceuticals (NASDAQ:VRTX) and Editas Medicine (NASDAQ:EDIT) are both healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their institutional ownership, media sentiment, dividends, valuation, risk, profitability, earnings and analyst recommendations.

In the previous week, Vertex Pharmaceuticals had 9 more articles in the media than Editas Medicine. MarketBeat recorded 17 mentions for Vertex Pharmaceuticals and 8 mentions for Editas Medicine. Vertex Pharmaceuticals' average media sentiment score of 0.93 beat Editas Medicine's score of 0.44 indicating that Vertex Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vertex Pharmaceuticals
9 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Editas Medicine
0 Very Positive mention(s)
1 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

91.0% of Vertex Pharmaceuticals shares are owned by institutional investors. Comparatively, 71.9% of Editas Medicine shares are owned by institutional investors. 0.2% of Vertex Pharmaceuticals shares are owned by company insiders. Comparatively, 3.1% of Editas Medicine shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Vertex Pharmaceuticals has a beta of 0.32, meaning that its stock price is 68% less volatile than the broader market. Comparatively, Editas Medicine has a beta of 2.09, meaning that its stock price is 109% more volatile than the broader market.

Vertex Pharmaceuticals presently has a consensus price target of $575.13, suggesting a potential upside of 9.19%. Editas Medicine has a consensus price target of $5.80, suggesting a potential upside of 123.94%. Given Editas Medicine's higher probable upside, analysts plainly believe Editas Medicine is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vertex Pharmaceuticals
0 Sell rating(s)
2 Hold rating(s)
20 Buy rating(s)
1 Strong Buy rating(s)
2.96
Editas Medicine
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.67

Vertex Pharmaceuticals has higher revenue and earnings than Editas Medicine. Editas Medicine is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Vertex Pharmaceuticals$12.00B11.14$3.95B$17.1830.66
Editas Medicine$40.52M9.82-$160.06M-$0.75N/A

Vertex Pharmaceuticals has a net margin of 35.00% compared to Editas Medicine's net margin of -157.32%. Vertex Pharmaceuticals' return on equity of 23.09% beat Editas Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Vertex Pharmaceuticals35.00% 23.09% 16.72%
Editas Medicine -157.32%-196.63%-38.17%

Summary

Vertex Pharmaceuticals beats Editas Medicine on 14 of the 17 factors compared between the two stocks.

How does Vertex Pharmaceuticals compare to Alphabet?

Alphabet (NASDAQ:GOOG) and Vertex Pharmaceuticals (NASDAQ:VRTX) are related large-cap companies, but which is the better stock? We will compare the two companies based on the strength of their valuation, profitability, earnings, media sentiment, risk, analyst recommendations, institutional ownership and dividends.

Alphabet has a net margin of 54.77% compared to Vertex Pharmaceuticals' net margin of 35.00%. Alphabet's return on equity of 51.32% beat Vertex Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Alphabet54.77% 51.32% 35.42%
Vertex Pharmaceuticals 35.00%23.09%16.72%

27.3% of Alphabet shares are held by institutional investors. Comparatively, 91.0% of Vertex Pharmaceuticals shares are held by institutional investors. 13.0% of Alphabet shares are held by insiders. Comparatively, 0.2% of Vertex Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

In the previous week, Alphabet had 105 more articles in the media than Vertex Pharmaceuticals. MarketBeat recorded 122 mentions for Alphabet and 17 mentions for Vertex Pharmaceuticals. Vertex Pharmaceuticals' average media sentiment score of 0.93 beat Alphabet's score of 0.46 indicating that Vertex Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alphabet
46 Very Positive mention(s)
14 Positive mention(s)
38 Neutral mention(s)
16 Negative mention(s)
6 Very Negative mention(s)
Neutral
Vertex Pharmaceuticals
9 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Alphabet has higher revenue and earnings than Vertex Pharmaceuticals. Alphabet is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alphabet$402.84B10.24$132.17B$19.9116.94
Vertex Pharmaceuticals$12.00B11.14$3.95B$17.1830.66

Alphabet currently has a consensus price target of $419.93, suggesting a potential upside of 24.49%. Vertex Pharmaceuticals has a consensus price target of $575.13, suggesting a potential upside of 9.19%. Given Alphabet's stronger consensus rating and higher possible upside, equities analysts clearly believe Alphabet is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alphabet
0 Sell rating(s)
4 Hold rating(s)
34 Buy rating(s)
6 Strong Buy rating(s)
3.05
Vertex Pharmaceuticals
0 Sell rating(s)
2 Hold rating(s)
20 Buy rating(s)
1 Strong Buy rating(s)
2.96

Alphabet has a beta of 1.21, meaning that its stock price is 21% more volatile than the broader market. Comparatively, Vertex Pharmaceuticals has a beta of 0.32, meaning that its stock price is 68% less volatile than the broader market.

Summary

Alphabet beats Vertex Pharmaceuticals on 13 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding VRTX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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VRTX vs. The Competition

MetricVertex PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$133.68B$3.94B$7.26B$13.03B
Dividend YieldN/A3.63%2.52%14.03%
P/E Ratio30.6613.73274.7225.67
Price / Sales11.141,309.75606.7080.64
Price / Cash29.9440.8828.0235.00
Price / Book7.1615.3310.496.43
Net Income$3.95B-$22.71M$3.50B$360.21M
7 Day Performance2.28%-4.79%-3.03%-2.82%
1 Month Performance-2.76%-8.35%-4.16%-4.06%
1 Year Performance33.24%27.10%13.20%3.86%

Vertex Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
VRTX
Vertex Pharmaceuticals
3.668 of 5 stars
$526.73
-0.2%
$575.13
+9.2%
+36.8%$133.68B$12.00B30.666,400
AMZN
Amazon.com
4.9824 of 5 stars
$258.45
+1.9%
$321.19
+24.3%
+12.0%$2.79T$775.68B20.791,576,000
AXSM
Axsome Therapeutics
3.154 of 5 stars
$205.49
-1.1%
$267.60
+30.2%
+66.1%$10.76B$638.50MN/A925
CRSP
CRISPR Therapeutics
2.5326 of 5 stars
$58.33
+3.1%
$67.94
+16.5%
-12.3%$5.64B$3.51MN/A393
EDIT
Editas Medicine
2.2763 of 5 stars
$2.83
+4.8%
$6.00
+112.0%
-22.5%$434.63M$40.52MN/A87

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This page (NASDAQ:VRTX) was last updated on 9/29/2026 by MarketBeat.com Staff.
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