Go Pro

Vertex Pharmaceuticals (VRTX) Competitors

Vertex Pharmaceuticals logo
$481.70 -1.63 (-0.34%)
Closing price 07/30/2026 04:00 PM Eastern
Extended Trading
$475.56 -6.13 (-1.27%)
As of 04:51 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

VRTX vs. AMZN, AXSM, CRSP, EDIT, and GOOG

Should you buy Vertex Pharmaceuticals stock or one of its competitors? MarketBeat compares Vertex Pharmaceuticals with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Vertex Pharmaceuticals include Amazon.com (AMZN), Axsome Therapeutics (AXSM), CRISPR Therapeutics (CRSP), Editas Medicine (EDIT), and Alphabet (GOOG).

How does Vertex Pharmaceuticals compare to Amazon.com?

Amazon.com (NASDAQ:AMZN) and Vertex Pharmaceuticals (NASDAQ:VRTX) are related large-cap companies, but which is the better business? We will contrast the two companies based on the strength of their dividends, media sentiment, valuation, institutional ownership, earnings, profitability, risk and analyst recommendations.

72.2% of Amazon.com shares are held by institutional investors. Comparatively, 91.0% of Vertex Pharmaceuticals shares are held by institutional investors. 8.9% of Amazon.com shares are held by insiders. Comparatively, 0.2% of Vertex Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Amazon.com has a beta of 1.46, suggesting that its share price is 46% more volatile than the broader market. Comparatively, Vertex Pharmaceuticals has a beta of 0.29, suggesting that its share price is 71% less volatile than the broader market.

Amazon.com currently has a consensus target price of $313.43, indicating a potential upside of 33.09%. Vertex Pharmaceuticals has a consensus target price of $559.61, indicating a potential upside of 16.17%. Given Amazon.com's stronger consensus rating and higher possible upside, equities research analysts plainly believe Amazon.com is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amazon.com
0 Sell rating(s)
3 Hold rating(s)
57 Buy rating(s)
0 Strong Buy rating(s)
2.95
Vertex Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
22 Buy rating(s)
0 Strong Buy rating(s)
2.88

Vertex Pharmaceuticals has a net margin of 35.51% compared to Amazon.com's net margin of 12.22%. Vertex Pharmaceuticals' return on equity of 23.86% beat Amazon.com's return on equity.

Company Net Margins Return on Equity Return on Assets
Amazon.com12.22% 19.92% 9.86%
Vertex Pharmaceuticals 35.51%23.86%17.13%

In the previous week, Amazon.com had 300 more articles in the media than Vertex Pharmaceuticals. MarketBeat recorded 342 mentions for Amazon.com and 42 mentions for Vertex Pharmaceuticals. Vertex Pharmaceuticals' average media sentiment score of 1.24 beat Amazon.com's score of 0.75 indicating that Vertex Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amazon.com
181 Very Positive mention(s)
71 Positive mention(s)
50 Neutral mention(s)
29 Negative mention(s)
6 Very Negative mention(s)
Positive
Vertex Pharmaceuticals
29 Very Positive mention(s)
4 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Amazon.com has higher revenue and earnings than Vertex Pharmaceuticals. Amazon.com is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amazon.com$716.92B3.53$77.67B$8.3628.17
Vertex Pharmaceuticals$12.00B10.19$3.95B$16.8628.57

Summary

Amazon.com and Vertex Pharmaceuticals tied by winning 8 of the 16 factors compared between the two stocks.

How does Vertex Pharmaceuticals compare to Axsome Therapeutics?

Axsome Therapeutics (NASDAQ:AXSM) and Vertex Pharmaceuticals (NASDAQ:VRTX) are both large-cap medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their dividends, institutional ownership, media sentiment, earnings, analyst recommendations, risk, profitability and valuation.

Axsome Therapeutics has a beta of 0.6, meaning that its share price is 40% less volatile than the broader market. Comparatively, Vertex Pharmaceuticals has a beta of 0.29, meaning that its share price is 71% less volatile than the broader market.

81.5% of Axsome Therapeutics shares are owned by institutional investors. Comparatively, 91.0% of Vertex Pharmaceuticals shares are owned by institutional investors. 20.6% of Axsome Therapeutics shares are owned by insiders. Comparatively, 0.2% of Vertex Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Vertex Pharmaceuticals has higher revenue and earnings than Axsome Therapeutics. Axsome Therapeutics is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Axsome Therapeutics$638.50M18.91-$183.17M-$3.73N/A
Vertex Pharmaceuticals$12.00B10.19$3.95B$16.8628.57

Axsome Therapeutics currently has a consensus target price of $261.48, indicating a potential upside of 11.44%. Vertex Pharmaceuticals has a consensus target price of $559.61, indicating a potential upside of 16.17%. Given Vertex Pharmaceuticals' higher possible upside, analysts plainly believe Vertex Pharmaceuticals is more favorable than Axsome Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Axsome Therapeutics
2 Sell rating(s)
0 Hold rating(s)
19 Buy rating(s)
2 Strong Buy rating(s)
2.91
Vertex Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
22 Buy rating(s)
0 Strong Buy rating(s)
2.88

Vertex Pharmaceuticals has a net margin of 35.51% compared to Axsome Therapeutics' net margin of -26.59%. Vertex Pharmaceuticals' return on equity of 23.86% beat Axsome Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Axsome Therapeutics-26.59% -267.16% -28.53%
Vertex Pharmaceuticals 35.51%23.86%17.13%

In the previous week, Vertex Pharmaceuticals had 29 more articles in the media than Axsome Therapeutics. MarketBeat recorded 42 mentions for Vertex Pharmaceuticals and 13 mentions for Axsome Therapeutics. Axsome Therapeutics' average media sentiment score of 1.29 beat Vertex Pharmaceuticals' score of 1.24 indicating that Axsome Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Axsome Therapeutics
11 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Vertex Pharmaceuticals
29 Very Positive mention(s)
4 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Vertex Pharmaceuticals beats Axsome Therapeutics on 11 of the 17 factors compared between the two stocks.

How does Vertex Pharmaceuticals compare to CRISPR Therapeutics?

CRISPR Therapeutics (NASDAQ:CRSP) and Vertex Pharmaceuticals (NASDAQ:VRTX) are both medical companies, but which is the superior business? We will compare the two businesses based on the strength of their institutional ownership, risk, analyst recommendations, earnings, valuation, profitability, media sentiment and dividends.

CRISPR Therapeutics has a beta of 1.71, meaning that its stock price is 71% more volatile than the broader market. Comparatively, Vertex Pharmaceuticals has a beta of 0.29, meaning that its stock price is 71% less volatile than the broader market.

69.2% of CRISPR Therapeutics shares are owned by institutional investors. Comparatively, 91.0% of Vertex Pharmaceuticals shares are owned by institutional investors. 5.2% of CRISPR Therapeutics shares are owned by insiders. Comparatively, 0.2% of Vertex Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

CRISPR Therapeutics presently has a consensus price target of $67.78, indicating a potential upside of 39.92%. Vertex Pharmaceuticals has a consensus price target of $559.61, indicating a potential upside of 16.17%. Given CRISPR Therapeutics' higher possible upside, analysts plainly believe CRISPR Therapeutics is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
CRISPR Therapeutics
1 Sell rating(s)
7 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.58
Vertex Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
22 Buy rating(s)
0 Strong Buy rating(s)
2.88

In the previous week, Vertex Pharmaceuticals had 34 more articles in the media than CRISPR Therapeutics. MarketBeat recorded 42 mentions for Vertex Pharmaceuticals and 8 mentions for CRISPR Therapeutics. Vertex Pharmaceuticals' average media sentiment score of 1.24 beat CRISPR Therapeutics' score of 0.88 indicating that Vertex Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
CRISPR Therapeutics
4 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Vertex Pharmaceuticals
29 Very Positive mention(s)
4 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Vertex Pharmaceuticals has a net margin of 35.51% compared to CRISPR Therapeutics' net margin of -13,856.54%. Vertex Pharmaceuticals' return on equity of 23.86% beat CRISPR Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
CRISPR Therapeutics-13,856.54% -25.66% -20.39%
Vertex Pharmaceuticals 35.51%23.86%17.13%

Vertex Pharmaceuticals has higher revenue and earnings than CRISPR Therapeutics. CRISPR Therapeutics is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
CRISPR Therapeutics$3.51M1,331.06-$581.60M-$6.22N/A
Vertex Pharmaceuticals$12.00B10.19$3.95B$16.8628.57

Summary

Vertex Pharmaceuticals beats CRISPR Therapeutics on 12 of the 17 factors compared between the two stocks.

How does Vertex Pharmaceuticals compare to Editas Medicine?

Editas Medicine (NASDAQ:EDIT) and Vertex Pharmaceuticals (NASDAQ:VRTX) are both medical companies, but which is the better stock? We will compare the two businesses based on the strength of their profitability, media sentiment, institutional ownership, earnings, risk, valuation, dividends and analyst recommendations.

Editas Medicine has a beta of 2.1, suggesting that its share price is 110% more volatile than the broader market. Comparatively, Vertex Pharmaceuticals has a beta of 0.29, suggesting that its share price is 71% less volatile than the broader market.

Vertex Pharmaceuticals has higher revenue and earnings than Editas Medicine. Editas Medicine is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Editas Medicine$40.52M6.50-$160.06M-$1.23N/A
Vertex Pharmaceuticals$12.00B10.19$3.95B$16.8628.57

Editas Medicine currently has a consensus price target of $5.40, indicating a potential upside of 100.74%. Vertex Pharmaceuticals has a consensus price target of $559.61, indicating a potential upside of 16.17%. Given Editas Medicine's higher probable upside, analysts plainly believe Editas Medicine is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Editas Medicine
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.57
Vertex Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
22 Buy rating(s)
0 Strong Buy rating(s)
2.88

In the previous week, Vertex Pharmaceuticals had 38 more articles in the media than Editas Medicine. MarketBeat recorded 42 mentions for Vertex Pharmaceuticals and 4 mentions for Editas Medicine. Vertex Pharmaceuticals' average media sentiment score of 1.24 beat Editas Medicine's score of 1.16 indicating that Vertex Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Editas Medicine
2 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Vertex Pharmaceuticals
29 Very Positive mention(s)
4 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Vertex Pharmaceuticals has a net margin of 35.51% compared to Editas Medicine's net margin of -281.59%. Vertex Pharmaceuticals' return on equity of 23.86% beat Editas Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Editas Medicine-281.59% -677.39% -58.25%
Vertex Pharmaceuticals 35.51%23.86%17.13%

71.9% of Editas Medicine shares are held by institutional investors. Comparatively, 91.0% of Vertex Pharmaceuticals shares are held by institutional investors. 3.1% of Editas Medicine shares are held by company insiders. Comparatively, 0.2% of Vertex Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Summary

Vertex Pharmaceuticals beats Editas Medicine on 13 of the 16 factors compared between the two stocks.

How does Vertex Pharmaceuticals compare to Alphabet?

Alphabet (NASDAQ:GOOG) and Vertex Pharmaceuticals (NASDAQ:VRTX) are related large-cap companies, but which is the superior business? We will contrast the two companies based on the strength of their profitability, institutional ownership, dividends, valuation, media sentiment, analyst recommendations, earnings and risk.

Alphabet has a beta of 1.23, meaning that its stock price is 23% more volatile than the broader market. Comparatively, Vertex Pharmaceuticals has a beta of 0.29, meaning that its stock price is 71% less volatile than the broader market.

In the previous week, Alphabet had 266 more articles in the media than Vertex Pharmaceuticals. MarketBeat recorded 308 mentions for Alphabet and 42 mentions for Vertex Pharmaceuticals. Vertex Pharmaceuticals' average media sentiment score of 1.24 beat Alphabet's score of 0.66 indicating that Vertex Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alphabet
188 Very Positive mention(s)
16 Positive mention(s)
42 Neutral mention(s)
37 Negative mention(s)
6 Very Negative mention(s)
Positive
Vertex Pharmaceuticals
29 Very Positive mention(s)
4 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Alphabet has higher revenue and earnings than Vertex Pharmaceuticals. Alphabet is trading at a lower price-to-earnings ratio than Vertex Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alphabet$402.84B10.04$132.17B$19.9116.76
Vertex Pharmaceuticals$12.00B10.19$3.95B$16.8628.57

Alphabet has a net margin of 54.77% compared to Vertex Pharmaceuticals' net margin of 35.51%. Alphabet's return on equity of 51.32% beat Vertex Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Alphabet54.77% 51.32% 35.42%
Vertex Pharmaceuticals 35.51%23.86%17.13%

Alphabet currently has a consensus target price of $410.09, indicating a potential upside of 22.90%. Vertex Pharmaceuticals has a consensus target price of $559.61, indicating a potential upside of 16.17%. Given Alphabet's stronger consensus rating and higher possible upside, equities analysts clearly believe Alphabet is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alphabet
0 Sell rating(s)
3 Hold rating(s)
29 Buy rating(s)
7 Strong Buy rating(s)
3.10
Vertex Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
22 Buy rating(s)
0 Strong Buy rating(s)
2.88

27.3% of Alphabet shares are owned by institutional investors. Comparatively, 91.0% of Vertex Pharmaceuticals shares are owned by institutional investors. 13.0% of Alphabet shares are owned by company insiders. Comparatively, 0.2% of Vertex Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Summary

Alphabet beats Vertex Pharmaceuticals on 13 of the 17 factors compared between the two stocks.

Get Vertex Pharmaceuticals News Delivered to You Automatically

Sign up to receive the latest news and ratings for VRTX and its competitors with MarketBeat's FREE daily newsletter.

Subscribe Now
SMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy.

New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding VRTX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
Skip Chart

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
Skip Chart

VRTX vs. The Competition

MetricVertex PharmaceuticalsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$122.67B$3.71B$7.04B$12.02B
Dividend YieldN/A2.13%2.65%10.11%
P/E Ratio28.5723.3527.6523.56
Price / Sales10.19183.26490.1877.94
Price / Cash27.50165.2551.7458.30
Price / Book6.558.0510.055.85
Net Income$3.95B$23.81M$3.60B$336.53M
7 Day Performance0.91%0.21%0.67%0.38%
1 Month Performance-3.03%-6.22%-3.28%-4.97%
1 Year Performance5.43%41.74%24.49%17.95%

Vertex Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
VRTX
Vertex Pharmaceuticals
4.2309 of 5 stars
$481.70
-0.3%
$559.61
+16.2%
+2.7%$122.67B$12.00B28.576,400
AMZN
Amazon.com
4.7796 of 5 stars
$231.39
-0.3%
$312.91
+35.2%
+2.3%$2.49T$716.92B27.681,576,000
AXSM
Axsome Therapeutics
3.0124 of 5 stars
$238.37
-1.1%
$261.48
+9.7%
+131.7%$12.40B$708.24MN/A380
CRSP
CRISPR Therapeutics
2.9042 of 5 stars
$46.73
+0.4%
$67.78
+45.0%
-16.0%$4.51B$1MN/A460
EDIT
Editas Medicine
3.0707 of 5 stars
$2.68
+3.1%
$5.40
+101.5%
+6.7%$262.39M$38.69MN/A230

Related Companies and Tools


This page (NASDAQ:VRTX) was last updated on 7/31/2026 by MarketBeat.com Staff.
From Our Partners